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IL141611A0 - Thiazoline acid derivatives - Google Patents

Thiazoline acid derivatives

Info

Publication number
IL141611A0
IL141611A0 IL14161199A IL14161199A IL141611A0 IL 141611 A0 IL141611 A0 IL 141611A0 IL 14161199 A IL14161199 A IL 14161199A IL 14161199 A IL14161199 A IL 14161199A IL 141611 A0 IL141611 A0 IL 141611A0
Authority
IL
Israel
Prior art keywords
acid derivatives
thiazoline acid
thiazoline
diagnosing
pyridyl
Prior art date
Application number
IL14161199A
Other languages
English (en)
Original Assignee
Univ Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida filed Critical Univ Florida
Publication of IL141611A0 publication Critical patent/IL141611A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/04Chelating agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Game Rules And Presentations Of Slot Machines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
IL14161199A 1998-08-31 1999-08-31 Thiazoline acid derivatives IL141611A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/144,103 US6083966A (en) 1998-08-31 1998-08-31 Thiazoline acid derivatives
PCT/US1999/019691 WO2000012493A1 (en) 1998-08-31 1999-08-31 Thiazoline acid derivatives

Publications (1)

Publication Number Publication Date
IL141611A0 true IL141611A0 (en) 2002-03-10

Family

ID=22507049

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14161199A IL141611A0 (en) 1998-08-31 1999-08-31 Thiazoline acid derivatives
IL141611A IL141611A (en) 1998-08-31 2001-02-22 History of thiazoline acid, optical antipodes, rheumatoids, salts and their pharmaceutical preparations in the preparation of drugs for the prevention and treatment of pathological diseases

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL141611A IL141611A (en) 1998-08-31 2001-02-22 History of thiazoline acid, optical antipodes, rheumatoids, salts and their pharmaceutical preparations in the preparation of drugs for the prevention and treatment of pathological diseases

Country Status (23)

Country Link
US (9) US6083966A (sh)
EP (1) EP1109795B1 (sh)
JP (3) JP4817498B2 (sh)
KR (1) KR20010074907A (sh)
CN (1) CN100455574C (sh)
AT (1) ATE317392T1 (sh)
AU (1) AU759851B2 (sh)
BR (1) BR9913441B1 (sh)
CA (1) CA2342210C (sh)
CZ (1) CZ2001711A3 (sh)
DE (1) DE69929807T2 (sh)
EA (1) EA200100261A1 (sh)
ES (1) ES2260933T3 (sh)
HU (1) HUP0103165A3 (sh)
IL (2) IL141611A0 (sh)
NO (1) NO321028B1 (sh)
NZ (1) NZ509899A (sh)
PL (1) PL346852A1 (sh)
PT (1) PT1109795E (sh)
TR (1) TR200100541T2 (sh)
UA (1) UA57161C2 (sh)
WO (1) WO2000012493A1 (sh)
YU (1) YU21801A (sh)

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US6083966A (en) * 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
CN1585639A (zh) * 1998-09-21 2005-02-23 佛罗里达大学研究基金会 抗疟疾制剂
EP1488791A3 (en) * 1998-09-21 2005-04-06 University Of Florida Research Foundation, Inc. Antimalarial agents
US6806363B1 (en) * 1999-04-16 2004-10-19 Mayo Foundation For Medical Education & Research Cobalamin conjugates useful as antitumor agents
AU785505B2 (en) 1999-10-15 2009-02-26 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
US6689788B1 (en) * 2000-08-25 2004-02-10 University Of Florida Method and composition for treatment of inflammatory bowel disease
TWI228512B (en) * 2000-10-25 2005-03-01 Mayo Foundation Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
EP1506162B1 (en) * 2002-05-15 2008-11-26 Genzyme Corporation Synthesis of benzonitriles and benzimidates
US20040044220A1 (en) * 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
WO2004017959A2 (en) * 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
US20060069134A1 (en) * 2002-10-01 2006-03-30 Kaneka Corporation Process for producing optically active alpha-substituted cysteine or salt thereof, intermediate therefor, and process for producing the same
US20040185028A1 (en) * 2003-03-19 2004-09-23 Zhenze Hu Antimicrobial compositions containing ethanolamine buffer and biguanide disinfectant
WO2005023310A2 (en) * 2003-09-09 2005-03-17 University Of Florida Research Foundation, Inc. Polyamine-metal chelator conjugates
AU2003270473A1 (en) * 2003-09-09 2005-04-27 University Of Florida Desferrithiocin derivatives and their use as iron chelators
WO2005055931A2 (en) * 2003-12-03 2005-06-23 University Of Medicine And Dentistry Of New Jersey Method of preventing survival of retrovirally cells and of inhibiting formation of infectious retroviruses
WO2005075475A1 (ja) * 2004-02-04 2005-08-18 Shionogi & Co., Ltd. Hivインテグラーゼ阻害活性を有するナフチリジン誘導体
BRPI0610644B8 (pt) * 2005-04-04 2021-05-25 Univ Florida composto e composição farmacêutica que compreende tal composto e um veículo ou diluente farmaceuticamente aceitável.
US7365371B2 (en) 2005-08-04 2008-04-29 Cree, Inc. Packages for semiconductor light emitting devices utilizing dispensed encapsulants
CA2684837A1 (en) * 2006-12-12 2008-10-30 Raymond J. Bergeron, Jr. Desferrithiocin analogue actinide decorporation agents
NZ579994A (en) 2007-03-15 2011-09-30 Univ Florida Desferrithiocin polyether analogues useful in the treatment of pathological conditions responsive to chelation or sequestration of trivalent metal
NZ590302A (en) * 2008-07-14 2013-02-22 Ferrokin Biosciences Inc Novel salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
CA2798082A1 (en) 2010-05-04 2011-11-10 Shire Llc Desazadesferrothiocin analogues as metal chelation agents
CN103562379A (zh) * 2011-05-19 2014-02-05 国立大学法人德岛大学 细胞分化诱导剂以及分化诱导方法
EP2790697B1 (en) 2011-12-16 2019-10-23 University of Florida Research Foundation, Inc. Uses of 4'-desferrithiocin analogs
JP6353751B2 (ja) * 2013-09-25 2018-07-04 国立大学法人電気通信大学 新規複素環式化合物及びその塩、並びに、発光基質組成物
WO2015077655A1 (en) 2013-11-22 2015-05-28 University Of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
WO2016176343A1 (en) 2015-04-27 2016-11-03 University Of Florida Research Foundation, Incorporated Metabolically programmed metal chelators and uses thereof

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MA26618A1 (fr) 1998-04-09 2004-12-20 Smithkline Beecham Corp Composes et compositions pharmaceutiques pour le traitement du paludisme
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US6083966A (en) 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
US6159983A (en) 1998-09-18 2000-12-12 University Of Florida Method and composition for treatment of inflammatory bowel disease
CN1585639A (zh) 1998-09-21 2005-02-23 佛罗里达大学研究基金会 抗疟疾制剂
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US20040044220A1 (en) * 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
AU2003270473A1 (en) * 2003-09-09 2005-04-27 University Of Florida Desferrithiocin derivatives and their use as iron chelators
WO2005023310A2 (en) 2003-09-09 2005-03-17 University Of Florida Research Foundation, Inc. Polyamine-metal chelator conjugates
CA2587558A1 (en) 2004-11-19 2006-05-26 Shiva Biomedical, Llc Methods of treating erythropoietin-resistance
BRPI0610644B8 (pt) * 2005-04-04 2021-05-25 Univ Florida composto e composição farmacêutica que compreende tal composto e um veículo ou diluente farmaceuticamente aceitável.
CA2684837A1 (en) * 2006-12-12 2008-10-30 Raymond J. Bergeron, Jr. Desferrithiocin analogue actinide decorporation agents
NZ579994A (en) * 2007-03-15 2011-09-30 Univ Florida Desferrithiocin polyether analogues useful in the treatment of pathological conditions responsive to chelation or sequestration of trivalent metal

Also Published As

Publication number Publication date
US6525080B1 (en) 2003-02-25
NZ509899A (en) 2003-12-19
BR9913441A (pt) 2001-10-23
JP2011178797A (ja) 2011-09-15
US7531563B2 (en) 2009-05-12
UA57161C2 (uk) 2003-06-16
EP1109795A1 (en) 2001-06-27
US20100094016A1 (en) 2010-04-15
US20030236417A1 (en) 2003-12-25
YU21801A (sh) 2005-07-19
NO321028B1 (no) 2006-02-27
HUP0103165A2 (hu) 2002-01-28
US7126004B2 (en) 2006-10-24
ATE317392T1 (de) 2006-02-15
WO2000012493A1 (en) 2000-03-09
ES2260933T3 (es) 2006-11-01
BR9913441B1 (pt) 2013-10-29
HUP0103165A3 (en) 2003-03-28
JP2002523500A (ja) 2002-07-30
NO20011003L (no) 2001-02-27
CN1313856A (zh) 2001-09-19
DE69929807D1 (de) 2006-04-20
DE69929807T2 (de) 2006-11-02
CN100455574C (zh) 2009-01-28
PL346852A1 (en) 2002-03-11
JP2014065730A (ja) 2014-04-17
KR20010074907A (ko) 2001-08-09
CA2342210C (en) 2009-03-10
US20050033057A1 (en) 2005-02-10
CZ2001711A3 (cs) 2001-09-12
CA2342210A1 (en) 2000-03-09
TR200100541T2 (tr) 2001-11-21
NO20011003D0 (no) 2001-02-27
JP4817498B2 (ja) 2011-11-16
PT1109795E (pt) 2006-06-30
IL141611A (en) 2006-12-31
EP1109795A4 (en) 2002-01-16
USRE39132E1 (en) 2006-06-13
JP5520875B2 (ja) 2014-06-11
US20070238767A1 (en) 2007-10-11
EA200100261A1 (ru) 2001-10-22
US6521652B1 (en) 2003-02-18
AU5789799A (en) 2000-03-21
US6083966A (en) 2000-07-04
AU759851B2 (en) 2003-05-01
US6559315B1 (en) 2003-05-06
US8008502B2 (en) 2011-08-30
HK1035720A1 (en) 2003-04-24
EP1109795B1 (en) 2006-02-08
WO2000012493A9 (en) 2002-04-11

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