IL137979A0 - Production, release preparation for aii antagonist-sustained and use thereof - Google Patents

Production, release preparation for aii antagonist-sustained and use thereof

Info

Publication number: IL137979A0
Authority: IL; Israel
Prior art keywords: sustained; release preparation; production; aii antagonist; angiotensin
Prior art date: 1998-03-04

Application number

IL13797999A

Other languages

English (en)

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-04

Filing date

1999-03-03

Publication date

2001-10-31

1999-03-03 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

2001-10-31 Publication of IL137979A0 publication Critical patent/IL137979A0/xx

Links

102000005862 Angiotensin II Human genes 0.000 abstract 2
101800000733 Angiotensin-2 Proteins 0.000 abstract 2
CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 abstract 2
229950006323 angiotensin ii Drugs 0.000 abstract 2
230000003042 antagnostic effect Effects 0.000 abstract 2
229920002988 biodegradable polymer Polymers 0.000 abstract 1
239000004621 biodegradable polymer Substances 0.000 abstract 1
230000036772 blood pressure Effects 0.000 abstract 1
230000027288 circadian rhythm Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003405 delayed action preparation Substances 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
229940002612 prodrug Drugs 0.000 abstract 1
239000000651 prodrug Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Inorganic Chemistry (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Plural Heterocyclic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IL13797999A 1998-03-04 1999-03-03 Production, release preparation for aii antagonist-sustained and use thereof IL137979A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP5236698		1998-03-04
PCT/JP1999/001011 WO1999044590A1 (en)	1998-03-04	1999-03-03	Sustained-release preparation for aii antagonist, production and use thereof

Publications (1)

Publication Number	Publication Date
IL137979A0 true IL137979A0 (en)	2001-10-31

Family

ID=12912818

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL13797999A IL137979A0 (en)	1998-03-04	1999-03-03	Production, release preparation for aii antagonist-sustained and use thereof

Country Status (21)

Country	Link
US (2)	US6589547B1 (pt)
EP (1)	EP1058541B1 (pt)
KR (1)	KR20010086245A (pt)
CN (1)	CN1291888A (pt)
AT (1)	ATE258430T1 (pt)
AU (1)	AU2745199A (pt)
BR (1)	BR9908474A (pt)
CA (1)	CA2318446C (pt)
DE (1)	DE69914460T2 (pt)
EE (1)	EE200000499A (pt)
ES (1)	ES2214013T3 (pt)
HU (1)	HUP0101439A3 (pt)
ID (1)	ID25640A (pt)
IL (1)	IL137979A0 (pt)
LT (1)	LT4800B (pt)
LV (1)	LV12585B (pt)
NO (1)	NO20004350L (pt)
PL (1)	PL342684A1 (pt)
SK (1)	SK11902000A3 (pt)
WO (1)	WO1999044590A1 (pt)
ZA (1)	ZA991706B (pt)

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KR20010086245A (ko) *	1998-03-04	2001-09-10	다케다 야쿠힌 고교 가부시키가이샤	Ａⅱ 길항제용 서방성 제제, 그것의 제조 및 용도
AU774799B2 (en)	1999-04-28	2004-07-08	Takeda Pharmaceutical Company Limited	Preventives / remedies / progression inhibitors for simplex retinopathy or preproliferating retinopathy
SE9903028D0 (sv) *	1999-08-27	1999-08-27	Astra Ab	New use
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CA2400845A1 (en) *	2000-02-21	2001-08-23	Takeda Chemical Industries, Ltd.	Sustained-release preparation of physiologically active compound slightly soluble in water and production process and use of the same
WO2002015935A1 (en) *	2000-08-25	2002-02-28	Takeda Chemical Industries, Ltd.	Fibrinogen lowering agents
WO2002034263A1 (en) *	2000-10-25	2002-05-02	Takeda Chemical Industries, Ltd.	Preventives/remedies for portal hypertension
US20040121008A1 (en) *	2001-03-16	2004-06-24	Keiko Shiraishi	Process for producing sustained release preparation
WO2003013609A1 (fr) *	2001-08-03	2003-02-20	Takeda Chemical Industries, Ltd.	Medicaments a liberation continue
BRPI0105509B8 (pt) *	2001-11-05	2021-05-25	Univ Minas Gerais	formulações do peptídeo angiotensina-(1-7) usando as ciclodextrinas, lipossomas e o polímero plga
WO2003041739A1 (fr)	2001-11-13	2003-05-22	Takeda Chemical Industries, Ltd.	Agents anticancer
WO2003047573A1 (en) *	2001-12-03	2003-06-12	Takeda Chemical Industries, Ltd.	Insulin resistance improving agents
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US7700074B2 (en) *	2002-02-07	2010-04-20	Pettegrew Jay W	Method and system for diagnosis of neuropsychiatric disorders including chronic alcoholism
AU2003292775A1 (en) *	2002-12-27	2004-07-29	Takeda Pharmaceutical Company Limited	Body weight gain inhibitor
US20050038093A1 (en) *	2003-05-02	2005-02-17	Boehringer Ingelheim International Gmbh	Treating diabetic retinopathy with angiotensin II receptor blockers
ATE437884T1 (de) *	2003-05-29	2009-08-15	Jay W Pettegrew	Glycerophosphocholin und derivate davon zur medizinischen abbildung von neuropsychiatrischen erkrankungen
US20060257842A1 (en) *	2003-05-29	2006-11-16	Pettegrew Jay W	Cryopreservation media and molecules
WO2005097109A1 (en) *	2004-04-01	2005-10-20	Daniel Batlle	Methods for achieving a protective ace2 expression level
EP1750862B1 (en)	2004-06-04	2011-01-05	Teva Pharmaceutical Industries Ltd.	Pharmaceutical composition containing irbesartan
KR20070073872A (ko) *	2004-10-07	2007-07-10	다케다 야쿠힌 고교 가부시키가이샤	대사 증후군의 예방 또는 치료용 제제
WO2006046528A1 (ja) *	2004-10-29	2006-05-04	Kowa Co., Ltd.	糸球体疾患治療剤
WO2006087394A1 (fr) *	2005-02-21	2006-08-24	Flamel Technologies	Forme pharmaceutique orale de losartan
US20090054502A1 (en) *	2005-03-30	2009-02-26	Takeda Pharmaceutical Company Limited	Benzimidazole Derivative and Use as Angiotensin II Antagonist
JP2009504800A (ja) *	2005-08-22	2009-02-05	アレンビクリミテッド	バルサルタンの調製方法
EA016728B1 (ru) *	2006-08-10	2012-07-30	Такеда Фармасьютикал Компани Лимитед	Фармацевтическая композиция
EP1897537A1 (en) *	2006-09-04	2008-03-12	Novartis AG	Composition comprising an angiotensin II receptor antagonist
PE20081364A1 (es) *	2006-09-04	2008-12-04	Novartis Ag	Composicion farmaceutica que comprende valsartan
EP1908469A1 (en)	2006-10-06	2008-04-09	Boehringer Ingelheim Vetmedica Gmbh	Angiotensin II receptor antagonist for the treatment of systemic diseases in cats
AR064381A1 (es)	2006-12-18	2009-04-01	Takeda Pharmaceutical	Composicion de liberacion sostenida y metodos para producirla
CN101011393B (zh) *	2007-02-16	2010-10-06	广州柏赛罗药业有限公司	厄贝沙坦胃内滞留型缓释药物组合物
AU2008235790B2 (en) *	2007-03-28	2013-06-06	Takeda Pharmaceutical Company Limited	Solid pharmaceutical composition comprising a benzimidazole-7-carboxylate derivative and a pH control agent
EP2281557A4 (en) *	2008-04-29	2011-08-31	Hanall Biopharma Co Ltd	PHARMACEUTICAL FORMULATION CONTAINING AN ANGIOTENSIN II RECEPTOR BLOCKING AGENT
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1999
- 1999-03-03 KR KR1020007008919A patent/KR20010086245A/ko not_active Abandoned
- 1999-03-03 CA CA002318446A patent/CA2318446C/en not_active Expired - Fee Related
- 1999-03-03 EE EEP200000499A patent/EE200000499A/xx unknown
- 1999-03-03 ID IDW20001680A patent/ID25640A/id unknown
- 1999-03-03 SK SK1190-2000A patent/SK11902000A3/sk unknown
- 1999-03-03 DE DE69914460T patent/DE69914460T2/de not_active Expired - Lifetime
- 1999-03-03 ES ES99907846T patent/ES2214013T3/es not_active Expired - Lifetime
- 1999-03-03 AU AU27451/99A patent/AU2745199A/en not_active Abandoned
- 1999-03-03 AT AT99907846T patent/ATE258430T1/de not_active IP Right Cessation
- 1999-03-03 HU HU0101439A patent/HUP0101439A3/hu unknown
- 1999-03-03 ZA ZA9901706A patent/ZA991706B/xx unknown
- 1999-03-03 IL IL13797999A patent/IL137979A0/xx unknown
- 1999-03-03 EP EP99907846A patent/EP1058541B1/en not_active Expired - Lifetime
- 1999-03-03 BR BR9908474-0A patent/BR9908474A/pt not_active IP Right Cessation
- 1999-03-03 PL PL99342684A patent/PL342684A1/xx unknown
- 1999-03-03 CN CN99803444A patent/CN1291888A/zh active Pending
- 1999-03-03 WO PCT/JP1999/001011 patent/WO1999044590A1/en not_active Ceased
- 1999-03-09 US US09/601,986 patent/US6589547B1/en not_active Expired - Fee Related
2000
- 2000-08-16 LV LVP-00-110A patent/LV12585B/en unknown
- 2000-08-31 LT LT2000082A patent/LT4800B/lt not_active IP Right Cessation
- 2000-09-01 NO NO20004350A patent/NO20004350L/no unknown
2003
- 2003-05-22 US US10/443,308 patent/US7294344B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EE200000499A (et)	2002-02-15
EP1058541A1 (en)	2000-12-13
CA2318446C (en)	2008-09-23
ID25640A (id)	2000-10-19
AU2745199A (en)	1999-09-20
PL342684A1 (en)	2001-07-02
LV12585B (en)	2001-03-20
CA2318446A1 (en)	1999-09-10
NO20004350L (no)	2000-10-03
US7294344B2 (en)	2007-11-13
ES2214013T3 (es)	2004-09-01
DE69914460D1 (de)	2004-03-04
SK11902000A3 (sk)	2001-02-12
WO1999044590A1 (en)	1999-09-10
LV12585A (en)	2000-12-20
EP1058541B1 (en)	2004-01-28
LT4800B (lt)	2001-06-25
ATE258430T1 (de)	2004-02-15
ZA991706B (en)	2000-10-03
KR20010086245A (ko)	2001-09-10
US20030198676A1 (en)	2003-10-23
CN1291888A (zh)	2001-04-18
US6589547B1 (en)	2003-07-08
LT2000082A (en)	2001-03-26
DE69914460T2 (de)	2004-10-28
BR9908474A (pt)	2000-12-05
HUP0101439A2 (hu)	2001-10-28
NO20004350D0 (no)	2000-09-01
HUP0101439A3 (en)	2002-09-30

Publication	Publication Date	Title
IL137979A0 (en)	2001-10-31	Production, release preparation for aii antagonist-sustained and use thereof
IS5404A (is)	2000-03-14	Lyfjablanda sem inniheldur klódrónat sem virkt innihaldsefni og síliseraðan örkristallaðan sellulósa sem burðarefni
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