IL128141A0 - Tetrahydroquinoline derivatives as eaa antagonists - Google Patents

Tetrahydroquinoline derivatives as eaa antagonists

Info

Publication number: IL128141A0
Authority: IL; Israel
Prior art keywords: tetrahydroquinoline derivatives; eaa antagonists; eaa; antagonists; tetrahydroquinoline
Prior art date: 1996-08-17

Application number

IL12814197A

Other languages

English (en)

Original Assignee

Glaxo Wellcome Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-17

Filing date

1997-08-14

Publication date

1999-11-30

1997-08-14 Application filed by Glaxo Wellcome Spa filed Critical Glaxo Wellcome Spa

1999-11-30 Publication of IL128141A0 publication Critical patent/IL128141A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Quinoline Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IL12814197A 1996-08-17 1997-08-14 Tetrahydroquinoline derivatives as eaa antagonists IL128141A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9617305.9A GB9617305D0 (en)	1996-08-17	1996-08-17	Heterocyclic compounds
PCT/EP1997/004440 WO1998007704A1 (en)	1996-08-17	1997-08-14	Tetrahydroquinoline derivatives as eaa antagonists

Publications (1)

Publication Number	Publication Date
IL128141A0 true IL128141A0 (en)	1999-11-30

Family

ID=10798623

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12814197A IL128141A0 (en)	1996-08-17	1997-08-14	Tetrahydroquinoline derivatives as eaa antagonists

Country Status (34)

Country	Link
US (1)	US6479488B1 (es)
EP (1)	EP0922034B1 (es)
JP (1)	JP4108129B2 (es)
KR (1)	KR100552864B1 (es)
CN (1)	CN1131214C (es)
AP (1)	AP877A (es)
AR (1)	AR008296A1 (es)
AT (1)	ATE221052T1 (es)
AU (1)	AU724473B2 (es)
BR (1)	BR9711311B1 (es)
CA (1)	CA2264118C (es)
CO (1)	CO4900066A1 (es)
CZ (1)	CZ296250B6 (es)
DE (1)	DE69714265T2 (es)
DK (1)	DK0922034T3 (es)
EA (1)	EA001704B1 (es)
ES (1)	ES2181030T3 (es)
GB (1)	GB9617305D0 (es)
HU (1)	HU225797B1 (es)
ID (1)	ID18095A (es)
IL (1)	IL128141A0 (es)
IS (1)	IS4953A (es)
MY (1)	MY116952A (es)
NO (1)	NO312241B1 (es)
NZ (1)	NZ333812A (es)
PE (1)	PE107098A1 (es)
PL (1)	PL194532B1 (es)
PT (1)	PT922034E (es)
SI (1)	SI0922034T1 (es)
TR (1)	TR199900336T2 (es)
TW (1)	TW449582B (es)
WO (1)	WO1998007704A1 (es)
YU (1)	YU6799A (es)
ZA (1)	ZA977326B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9706294D0 (en) *	1997-03-26	1997-05-14	Glaxo Wellcome Spa	Heterocyclic compound
MY125037A (en) *	1998-06-10	2006-07-31	Glaxo Wellcome Spa	1,2,3,4 tetrahydroquinoline derivatives
US6455734B1 (en)	2000-08-09	2002-09-24	Magnesium Diagnostics, Inc.	Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
GB9929037D0 (en)	1999-12-08	2000-02-02	Glaxo Wellcome Spa	Heterocyclic derivatives
DE10132725A1 (de)	2001-07-05	2006-08-03	Grünenthal GmbH	Substituierte γ-Lactonverbindungen
DE60206198T2 (de) *	2001-12-28	2006-06-14	Acadia Pharm Inc	Tetrahydrochinolinderivate als muscarinische agonisten
US20050250767A1 (en) *	2003-01-23	2005-11-10	Weiner David M	Use of N-desmethylclozapine to treat human neuropsychiatric disease
CN1741803A (zh) *	2003-01-23	2006-03-01	阿卡蒂亚药品公司	N－脱甲基氯氮平在治疗人神经精神疾病中的用途
US20050085463A1 (en) *	2003-01-23	2005-04-21	Weiner David M.	Use of N-desmethylclozapine to treat human neuropsychiatric disease
EP1596867A4 (en) *	2003-02-19	2006-03-22	Merck & Co Inc	TREATMENT OF PSYCHOSIS WITH A MUSCARIN M1 RECEPTOR ECTOPIC ACTIVATOR
CA2550735A1 (en) *	2003-12-22	2005-07-14	Acadia Pharmaceuticals Inc.	Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
JP2007536216A (ja) *	2004-04-01	2007-12-13	アカディアファーマシューティカルズ，インコーポレーテッド	固体ｎ−デスメチルクロザピンおよびその結晶形を合成および単離する方法
RU2451014C2 (ru) *	2005-07-22	2012-05-20	Мотида Фармасьютикал Ко., Лтд.	Новое производное гетероциклиден ацетамида
NZ565080A (en)	2005-07-22	2011-03-31	Mochida Pharm Co Ltd	Novel heterocyclidene acetamide derivative
WO2007033180A1 (en)	2005-09-12	2007-03-22	Abela Pharmaceuticals, Inc.	Materials for facilitating administration of dimethyl sulfoxide (dmso) and related compounds
EP1937286B1 (en)	2005-09-12	2016-03-09	Abela Pharmaceuticals, Inc.	Compositions comprising dimethyl sulfoxide (dmso)
US8480797B2 (en)	2005-09-12	2013-07-09	Abela Pharmaceuticals, Inc.	Activated carbon systems for facilitating use of dimethyl sulfoxide (DMSO) by removal of same, related compounds, or associated odors
EP1966229B1 (en)	2005-09-12	2015-10-21	Abela Pharmaceuticals, Inc.	Systems for removing dimethyl sulfoxide (dmso) or related compounds, or odors associated with same
WO2007053618A1 (en) *	2005-10-31	2007-05-10	Acadia Pharmaceuticals Inc.	Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders
BRPI0921494A2 (pt)	2008-11-03	2018-10-30	Prad Reasearch And Development Ltd	método de planejamento de uma operação de amostragem para uma formação subterrãnea, método de contolar uma operação de amostragem de formação subterrânea, método de controlar uma operação de perfuração para uma formação subterrãnea, e método de realizar uma amostragem durante a operação de perfuração.
JP5947721B2 (ja)	2009-10-30	2016-07-06	アベラファーマスーティカルズインコーポレイテッド	変形性関節症を治療するためのジメチルスルホキシド（ｄｍｓｏ）およびメチルスルホニルメタン（ｍｓｍ）製剤
EP3718547A1 (en)	2011-10-03	2020-10-07	The University of Utah Research Foundation	Application of 5-ht6 receptor antagonists for the alleviation of cognitive deficits of down syndrome

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69029668T2 (de) *	1989-03-08	1997-08-07	Merck Sharp & Dohme	Tetrahydroquinolin-Derivate, verwendbar bei neurodegenerativen Krankheiten
TR199800531T1 (xx) *	1995-09-29	1998-06-22	Glaxo Wellcome Spa	NMDA antagonistleri olarak tetrahidrokinolinler.

1996
- 1996-08-17 GB GBGB9617305.9A patent/GB9617305D0/en active Pending
1997
- 1997-08-14 WO PCT/EP1997/004440 patent/WO1998007704A1/en not_active Ceased
- 1997-08-14 AT AT97943809T patent/ATE221052T1/de not_active IP Right Cessation
- 1997-08-14 YU YU6799A patent/YU6799A/sh unknown
- 1997-08-14 DK DK97943809T patent/DK0922034T3/da active
- 1997-08-14 AR ARP970103703A patent/AR008296A1/es active IP Right Grant
- 1997-08-14 ZA ZA977326A patent/ZA977326B/xx unknown
- 1997-08-14 IL IL12814197A patent/IL128141A0/xx not_active IP Right Cessation
- 1997-08-14 ES ES97943809T patent/ES2181030T3/es not_active Expired - Lifetime
- 1997-08-14 AU AU45518/97A patent/AU724473B2/en not_active Ceased
- 1997-08-14 AP APAP/P/1999/001459A patent/AP877A/en active
- 1997-08-14 ID IDP972834A patent/ID18095A/id unknown
- 1997-08-14 US US09/147,568 patent/US6479488B1/en not_active Expired - Fee Related
- 1997-08-14 NZ NZ333812A patent/NZ333812A/xx active Application Revival
- 1997-08-14 MY MYPI97003742A patent/MY116952A/en unknown
- 1997-08-14 SI SI9730404T patent/SI0922034T1/xx unknown
- 1997-08-14 EA EA199900121A patent/EA001704B1/ru not_active IP Right Cessation
- 1997-08-14 CN CN97197233A patent/CN1131214C/zh not_active Expired - Fee Related
- 1997-08-14 EP EP97943809A patent/EP0922034B1/en not_active Expired - Lifetime
- 1997-08-14 PE PE1997000718A patent/PE107098A1/es not_active Application Discontinuation
- 1997-08-14 BR BRPI9711311-5A patent/BR9711311B1/pt not_active IP Right Cessation
- 1997-08-14 CO CO97046782A patent/CO4900066A1/es unknown
- 1997-08-14 HU HU9903108A patent/HU225797B1/hu not_active IP Right Cessation
- 1997-08-14 JP JP51037298A patent/JP4108129B2/ja not_active Expired - Fee Related
- 1997-08-14 PT PT97943809T patent/PT922034E/pt unknown
- 1997-08-14 KR KR1019997001280A patent/KR100552864B1/ko not_active Expired - Fee Related
- 1997-08-14 TR TR1999/00336T patent/TR199900336T2/xx unknown
- 1997-08-14 CZ CZ0052999A patent/CZ296250B6/cs not_active IP Right Cessation
- 1997-08-14 CA CA002264118A patent/CA2264118C/en not_active Expired - Fee Related
- 1997-08-14 PL PL97331562A patent/PL194532B1/pl not_active IP Right Cessation
- 1997-08-14 DE DE69714265T patent/DE69714265T2/de not_active Expired - Lifetime
- 1997-08-30 TW TW086112442A patent/TW449582B/zh not_active IP Right Cessation
1999
- 1999-01-22 IS IS4953A patent/IS4953A/is unknown
- 1999-02-16 NO NO19990723A patent/NO312241B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
US6479488B1 (en)	2002-11-12
HU225797B1 (en)	2007-09-28
ATE221052T1 (de)	2002-08-15
CA2264118A1 (en)	1998-02-26
JP4108129B2 (ja)	2008-06-25
AR008296A1 (es)	1999-12-29
EP0922034A1 (en)	1999-06-16
NO990723D0 (no)	1999-02-16
CZ296250B6 (cs)	2006-02-15
NO990723L (no)	1999-04-14
PE107098A1 (es)	1999-01-15
TW449582B (en)	2001-08-11
CZ52999A3 (cs)	1999-07-14
NO312241B1 (no)	2002-04-15
DK0922034T3 (da)	2002-11-18
MY116952A (en)	2004-04-30
GB9617305D0 (en)	1996-09-25
EP0922034B1 (en)	2002-07-24
ID18095A (id)	1998-02-26
YU6799A (sh)	2000-03-21
AU4551897A (en)	1998-03-06
PL331562A1 (en)	1999-07-19
CA2264118C (en)	2008-06-17
KR100552864B1 (ko)	2006-02-20
EA199900121A1 (ru)	1999-10-28
WO1998007704A1 (en)	1998-02-26
DE69714265T2 (de)	2003-03-06
BR9711311B1 (pt)	2009-01-13
JP2001508031A (ja)	2001-06-19
CN1131214C (zh)	2003-12-17
DE69714265D1 (de)	2002-08-29
BR9711311A (pt)	1999-08-17
PT922034E (pt)	2002-12-31
KR20000068172A (ko)	2000-11-25
NZ333812A (en)	2000-07-28
ES2181030T3 (es)	2003-02-16
AP9901459A0 (en)	1999-03-31
ZA977326B (en)	1999-02-15
HUP9903108A3 (en)	2004-04-28
PL194532B1 (pl)	2007-06-29
TR199900336T2 (xx)	1999-04-21
EA001704B1 (ru)	2001-06-25
CN1227544A (zh)	1999-09-01
AP877A (en)	2000-09-27
SI0922034T1 (en)	2003-02-28
AU724473B2 (en)	2000-09-21
IS4953A (is)	1999-01-22
CO4900066A1 (es)	2000-03-27

Publication	Publication Date	Title
IL143782A0 (en)	2002-04-21	Quinoline derivatives
AP2000001933A0 (en)	2000-12-31	Quinoline derivatives
IL140346A0 (en)	2002-02-10	Quinoline derivatives
IL128141A0 (en)	1999-11-30	Tetrahydroquinoline derivatives as eaa antagonists
CY2505B1 (en)	2005-12-23	Quinoline derivatives as nk3 antagonists
AP9500745A0 (en)	1995-07-31	Quinoline derivatives
ZA97913B (en)	1998-08-04	Substituted quinazolines derivatives
IL132192A0 (en)	2001-03-19	Substituted 3-cyano quinolines
IL140009A0 (en)	2002-02-10	Quinoline derivatives
IL127432A0 (en)	1999-10-28	Substituted benzimidazole derivatives
PL344694A1 (en)	2001-11-19	Tetrahydroquinoline derivatives as glycine antagonists
GB9404378D0 (en)	1994-04-20	Quinoline derivatives
ZA954269B (en)	1996-05-14	Quinoline derivatives
GB9413150D0 (en)	1994-08-24	Quinoline derivatives
GB9402275D0 (en)	1994-03-30	Quinoline derivatives
EG24161A (en)	2008-08-20	Carbostyril derivatives
HK1018452A (en)	1999-12-24	Tetrahydroquinoline derivatives as eaa antagonists
HUP9701548A3 (en)	2001-04-28	1-carba-(dethia)-cephalosporin derivatives
HU9603342D0 (en)	1997-01-28	Quinoline derivatives as leukotriene antagonists
GB9616476D0 (en)	1996-09-25	6-aryl-(methyl-or methylidone)-quinoline derivatives as voltage-gated
SI1086093T1 (sl)	2005-12-31	Derivati tetrahidrokinolina kot antagonisti glicina
GB9711030D0 (en)	1997-07-23	Quinoline leukrotriene antagonists
GB9402306D0 (en)	1994-03-30	Quinoline derivatives
IL139301A0 (en)	2001-11-25	Quinoline derivatives
GB9413937D0 (en)	1994-08-31	Quinoline derivatives

Legal Events

Date	Code	Title
2004-06-20	FF	Patent granted
2004-07-25	KB	Patent renewed
2007-09-20	KB	Patent renewed
2012-04-30	MM9K	Patent not in force due to non-payment of renewal fees