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IE801729L - A morpholine derivative - Google Patents

A morpholine derivative

Info

Publication number
IE801729L
IE801729L IE801729A IE172980A IE801729L IE 801729 L IE801729 L IE 801729L IE 801729 A IE801729 A IE 801729A IE 172980 A IE172980 A IE 172980A IE 801729 L IE801729 L IE 801729L
Authority
IE
Ireland
Prior art keywords
morpholine derivative
antimycotics
oxides
phenyl
salts
Prior art date
Application number
IE801729A
Other versions
IE52642B1 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH756079A external-priority patent/CH644113A5/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IE801729L publication Critical patent/IE801729L/en
Publication of IE52642B1 publication Critical patent/IE52642B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Morpholine derivatives of the formula:- <IMAGE> wherein R represents ethyl or phenyl, as well as their salts and N-oxides, possesses fungicidal activity and can be used as antimycotics, especially for combating Candida albicans. [EP0024334A1]
IE1729/80A 1979-08-17 1980-08-15 Morpholine derivatives,process for preparing them and use of said morpholine derivatives in pharmaceutical preparations IE52642B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH756079A CH644113A5 (en) 1979-08-17 1979-08-17 N-substituted 2,6-dimethylmorpholine compounds
CH418780 1980-05-29

Publications (2)

Publication Number Publication Date
IE801729L true IE801729L (en) 1981-02-17
IE52642B1 IE52642B1 (en) 1988-01-06

Family

ID=25694874

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1729/80A IE52642B1 (en) 1979-08-17 1980-08-15 Morpholine derivatives,process for preparing them and use of said morpholine derivatives in pharmaceutical preparations

Country Status (31)

Country Link
EP (1) EP0024334B1 (en)
AR (1) AR225318A1 (en)
AT (1) ATE4206T1 (en)
AU (1) AU530398B2 (en)
BG (1) BG60798B2 (en)
CA (1) CA1128943A (en)
CS (1) CS402091A3 (en)
CU (1) CU35298A (en)
DE (3) DE3029966A1 (en)
DK (1) DK150509C (en)
ES (2) ES8200355A1 (en)
FI (1) FI69455C (en)
FR (1) FR2463767B1 (en)
GB (1) GB2056454B (en)
HR (1) HRP930340B1 (en)
HU (1) HU182189B (en)
IE (1) IE52642B1 (en)
IL (1) IL60813A (en)
IT (1) IT1220970B (en)
LU (1) LU82713A1 (en)
MC (1) MC1345A1 (en)
MY (1) MY8500272A (en)
NL (1) NL8004537A (en)
NO (1) NO153176C (en)
NZ (1) NZ194628A (en)
PH (1) PH15480A (en)
PT (1) PT71708B (en)
SE (1) SE447730B (en)
SI (1) SI8011754A8 (en)
YU (1) YU43475B (en)
ZW (1) ZW15780A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3421810A1 (en) * 1984-06-12 1985-12-12 Basf Ag, 6700 Ludwigshafen PHENYLALKYLAMINE - BIOREGULATORS
CA2008775C (en) * 1989-02-24 1998-12-22 Alberto Ferro Nail lacquer
EP0446585A1 (en) * 1990-03-12 1991-09-18 F. Hoffmann-La Roche Ag Control of fungal infections in aquaculture
EP1749825A1 (en) * 2005-07-28 2007-02-07 Galderma S.A. Process of producing amorolfine
EP1749826A1 (en) * 2005-07-28 2007-02-07 Galderma S.A. Process of producing bepromoline
EP1842848A1 (en) * 2006-04-03 2007-10-10 Galderma S.A. Process for producing 3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propionaldehyde and cis-4{3-[4-(1,1-dimethyl-propyl)-phenyl]2-methyl-propyl}-2,6-dimethyl-morpholine (amorolfine)
EP1935889A1 (en) * 2006-12-21 2008-06-25 Galderma S.A. Process of producing amorolfine
ITFI20090032A1 (en) 2009-02-20 2010-08-21 Synteco S P A Prodotti Di Sintesi Per L Ind INDUSTRIAL PRODUCTION PROCESS OF CHLORIDATED AMOROLFIN

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT354187B (en) * 1976-11-22 1979-12-27 Hoffmann La Roche FUNGICIDE AGENT
DE2656747C2 (en) * 1976-12-15 1984-07-05 Basf Ag, 6700 Ludwigshafen Morpholine derivatives
ZA792242B (en) * 1978-05-16 1980-05-28 Hoffmann La Roche Heterocyclic compounds
DE2830127A1 (en) * 1978-07-08 1980-01-17 Basf Ag N-ARYL PROPYL SUBSTITUTED CYCLIC AMINES
DE2830999A1 (en) * 1978-07-14 1980-01-31 Basf Ag METHOD FOR PRODUCING STEREOISOMERS N-ARALKYL-2,6-DIMETHYLMORPHOLINES
EP0008686B1 (en) * 1978-08-08 1983-04-20 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Synthesis of phenyl-propyl morpholine and piperidine derivatives
DE2907614A1 (en) * 1979-02-27 1980-09-04 Basf Ag OPTICAL ACTIVE SHAPES OF THE 1- CORNER CLAMP ON 3- (P-TERT.-BUTHYLPHENYL) -2- METHYLPROPYL CORNER CLAMP ON -CIS-3,5- DIMETHYLMORPHOLINS

Also Published As

Publication number Publication date
ES494314A0 (en) 1981-11-01
HU182189B (en) 1983-12-28
LU82713A1 (en) 1982-05-10
AU530398B2 (en) 1983-07-14
IL60813A0 (en) 1980-10-26
FI69455C (en) 1986-02-10
BG60798B2 (en) 1996-03-29
EP0024334A1 (en) 1981-03-04
DK150509C (en) 1987-10-12
SI8011754A8 (en) 1997-06-30
YU175480A (en) 1983-02-28
SE447730B (en) 1986-12-08
SE8005784L (en) 1981-02-18
GB2056454A (en) 1981-03-18
FI69455B (en) 1985-10-31
FR2463767B1 (en) 1985-07-12
DE19375077I2 (en) 2001-04-12
AR225318A1 (en) 1982-03-15
IT1220970B (en) 1990-06-21
NO153176C (en) 1986-01-29
IT8023283A0 (en) 1980-07-07
ZW15780A1 (en) 1981-03-18
DE3029966A1 (en) 1981-03-26
ATE4206T1 (en) 1983-08-15
HRP930340B1 (en) 1996-12-31
CS402091A3 (en) 1992-05-13
AU6132180A (en) 1981-02-19
NL8004537A (en) 1981-02-19
NO802453L (en) 1981-02-18
MY8500272A (en) 1985-12-31
FR2463767A1 (en) 1981-02-27
DE3064267D1 (en) 1983-08-25
EP0024334B1 (en) 1983-07-20
CA1128943A (en) 1982-08-03
IE52642B1 (en) 1988-01-06
YU43475B (en) 1989-08-31
GB2056454B (en) 1983-11-09
ES8201563A1 (en) 1982-01-01
NO153176B (en) 1985-10-21
FI802418A7 (en) 1981-02-18
ES8200355A1 (en) 1981-11-01
PT71708A (en) 1980-10-01
IL60813A (en) 1984-06-29
CU35298A (en) 1982-03-28
DK150509B (en) 1987-03-16
NZ194628A (en) 1984-09-28
PT71708B (en) 1982-04-06
ES499957A0 (en) 1982-01-01
PH15480A (en) 1983-01-27
DK355180A (en) 1981-02-18
MC1345A1 (en) 1981-06-22

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Legal Events

Date Code Title Description
MM9A Patent lapsed through non-payment of renewal fee