HUP0200358A3 - Process for the preparation of (2r)-2-propyloctanoic acid - Google Patents
Process for the preparation of (2r)-2-propyloctanoic acidInfo
- Publication number
- HUP0200358A3 HUP0200358A3 HU0200358A HUP0200358A HUP0200358A3 HU P0200358 A3 HUP0200358 A3 HU P0200358A3 HU 0200358 A HU0200358 A HU 0200358A HU P0200358 A HUP0200358 A HU P0200358A HU P0200358 A3 HUP0200358 A3 HU P0200358A3
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- propyloctanoic acid
- propyloctanoic
- acid
- Prior art date
Links
- YCYMCMYLORLIJX-SNVBAGLBSA-N (2r)-2-propyloctanoic acid Chemical compound CCCCCC[C@H](C(O)=O)CCC YCYMCMYLORLIJX-SNVBAGLBSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
- B01J23/42—Platinum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J21/00—Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
- B01J21/18—Carbon
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3975899 | 1999-02-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0200358A2 HUP0200358A2 (hu) | 2002-05-29 |
| HUP0200358A3 true HUP0200358A3 (en) | 2003-03-28 |
Family
ID=12561862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0200358A HUP0200358A3 (en) | 1999-02-18 | 2000-02-17 | Process for the preparation of (2r)-2-propyloctanoic acid |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6608221B1 (hu) |
| EP (3) | EP1721882A1 (hu) |
| JP (2) | JP4752989B2 (hu) |
| KR (1) | KR100666423B1 (hu) |
| CN (4) | CN101100422A (hu) |
| AT (1) | ATE359256T1 (hu) |
| AU (1) | AU776927B2 (hu) |
| BR (1) | BR0008261A (hu) |
| CA (1) | CA2364308C (hu) |
| DE (1) | DE60034316T2 (hu) |
| ES (1) | ES2283287T3 (hu) |
| HU (1) | HUP0200358A3 (hu) |
| MX (1) | MXPA01008241A (hu) |
| NO (1) | NO20013971L (hu) |
| NZ (1) | NZ513569A (hu) |
| RU (1) | RU2297406C2 (hu) |
| TW (1) | TWI268921B (hu) |
| WO (1) | WO2000048982A1 (hu) |
| ZA (1) | ZA200106500B (hu) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI268921B (en) * | 1999-02-18 | 2006-12-21 | Ono Pharmaceutical Co | A process for preparing (2R)-2-propyloctanoic acid |
| JP4178405B2 (ja) | 2001-07-18 | 2008-11-12 | 小野薬品工業株式会社 | 脳虚血疾患治療剤 |
| JP2005298334A (ja) * | 2001-12-19 | 2005-10-27 | Ono Pharmaceut Co Ltd | 新規な中間体化合物およびそれを用いる化合物の製造方法 |
| CA2540670A1 (en) * | 2003-10-03 | 2005-04-14 | Ono Pharmaceutical Co., Ltd. | Drug containing (2r)-2-propyloctanoic acid as the active ingredient |
| AU2004277828A1 (en) * | 2003-10-03 | 2005-04-14 | Ono Pharmaceutical Co., Ltd. | Infusion preparation containing (2R)-2-propyloctanoic acid as the active ingredient |
| US7928143B2 (en) * | 2003-10-03 | 2011-04-19 | Ono Pharmaceutical Co., Ltd. | Method for preventing and/or treating neurodegenerative diseases |
| WO2005105722A1 (ja) * | 2004-04-28 | 2005-11-10 | Ono Pharmaceutical Co., Ltd. | (2r)−2−プロピルオクタン酸とアミンとからなる結晶 |
| US7495029B2 (en) * | 2004-11-16 | 2009-02-24 | Merck & Co., Inc | Prodrugs of (2R)-2-propyloctanoic acid for the treatment of stroke |
| JPWO2006075596A1 (ja) * | 2005-01-13 | 2008-06-12 | 株式会社クラレ | 2−アリルカルボン酸化合物の製造方法 |
| JPWO2006098292A1 (ja) | 2005-03-15 | 2008-08-21 | 小野薬品工業株式会社 | 眼疾患治療剤 |
| JP5050851B2 (ja) | 2005-06-27 | 2012-10-17 | 小野薬品工業株式会社 | 疼痛治療剤 |
| RU2008119454A (ru) | 2005-10-18 | 2009-11-27 | Оно Фармасьютикал Ко., Лтд. (Jp) | Лекарственное средство для защиты моторного нейрона у пациентов с боковым амиотрофическим склерозом |
| US20090203783A1 (en) | 2005-12-22 | 2009-08-13 | Ono Pharmaceutical Co., Ltd. | Therapeutic agent for acute cerebral infarct |
| US20090118542A1 (en) * | 2006-02-16 | 2009-05-07 | Shigeya Yamazaki | Process for Production of Optically Active Carboxlic Acid Compound |
| US20090325862A1 (en) * | 2006-05-04 | 2009-12-31 | Christian Steinkuhler | Histone Deacetylase Inhibitors for the Treatment of Neurodegeneration |
| CN102417445B (zh) * | 2011-11-05 | 2013-11-13 | 中国科学院山西煤炭化学研究所 | 一种由马来酸合成丁二酸的方法 |
| CN102675166B (zh) * | 2012-05-11 | 2014-03-26 | 山东齐都药业有限公司 | 用于制备2-丙基庚酸的新中间体、其制备方法及2-丙基庚酸的制备方法 |
| CN102786407B (zh) * | 2012-08-15 | 2014-04-16 | 湖北大学 | 一种制备(2r)-2-丙基辛酸的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2317019A1 (de) * | 1972-04-27 | 1973-11-08 | Upjohn Co | Neue 4,5-didehydro-prostaglandine |
| JPH0672123B2 (ja) | 1986-08-21 | 1994-09-14 | セントラル硝子株式会社 | トリフルオロメチル基を有するシクロヘキサンカルボン酸の製造方法 |
| JP2868183B2 (ja) * | 1988-02-29 | 1999-03-10 | 株式式社三和化学研究所 | 光学活性を有する4−オキソ−1−ベンゾピラン−2−カルボン酸誘導体の製法、その合成用中間体並びに該中間体の製法 |
| US5202474A (en) * | 1989-06-22 | 1993-04-13 | Monsanto Company | Asymmetric catalytic hydrogenation of α-arylpropenoic acids |
| DK0632008T3 (da) | 1993-06-01 | 1998-09-23 | Ono Pharmaceutical Co | Pentansyrederivater |
| JP3032447B2 (ja) | 1995-04-24 | 2000-04-17 | 小野薬品工業株式会社 | 光学活性な2−プロピルオクタン酸の製造方法 |
| JP3084345B2 (ja) * | 1995-04-26 | 2000-09-04 | 小野薬品工業株式会社 | 光学活性な2−プロピルオクタン酸の製造方法 |
| TW509672B (en) | 1998-05-12 | 2002-11-11 | Ono Pharmaceutical Co | Novel intermediate compounds and processes for the production of optical active octanoic acid derivatives |
| TWI268921B (en) * | 1999-02-18 | 2006-12-21 | Ono Pharmaceutical Co | A process for preparing (2R)-2-propyloctanoic acid |
| WO2005105722A1 (ja) * | 2004-04-28 | 2005-11-10 | Ono Pharmaceutical Co., Ltd. | (2r)−2−プロピルオクタン酸とアミンとからなる結晶 |
-
2000
- 2000-02-16 TW TW089102580A patent/TWI268921B/zh not_active IP Right Cessation
- 2000-02-17 EP EP06012510A patent/EP1721882A1/en not_active Withdrawn
- 2000-02-17 BR BR0008261-9A patent/BR0008261A/pt not_active Application Discontinuation
- 2000-02-17 WO PCT/JP2000/000900 patent/WO2000048982A1/ja not_active Ceased
- 2000-02-17 DE DE60034316T patent/DE60034316T2/de not_active Expired - Lifetime
- 2000-02-17 CN CNA2006100997275A patent/CN101100422A/zh active Pending
- 2000-02-17 EP EP06012511A patent/EP1714956A1/en not_active Withdrawn
- 2000-02-17 CN CNB2004100927127A patent/CN100430364C/zh not_active Expired - Fee Related
- 2000-02-17 AU AU25730/00A patent/AU776927B2/en not_active Ceased
- 2000-02-17 ES ES00904007T patent/ES2283287T3/es not_active Expired - Lifetime
- 2000-02-17 EP EP00904007A patent/EP1153910B1/en not_active Expired - Lifetime
- 2000-02-17 JP JP2000599723A patent/JP4752989B2/ja not_active Expired - Fee Related
- 2000-02-17 US US09/890,651 patent/US6608221B1/en not_active Expired - Fee Related
- 2000-02-17 CA CA002364308A patent/CA2364308C/en not_active Expired - Fee Related
- 2000-02-17 MX MXPA01008241A patent/MXPA01008241A/es active IP Right Grant
- 2000-02-17 NZ NZ513569A patent/NZ513569A/xx not_active IP Right Cessation
- 2000-02-17 AT AT00904007T patent/ATE359256T1/de not_active IP Right Cessation
- 2000-02-17 RU RU2001125501/04A patent/RU2297406C2/ru active
- 2000-02-17 CN CNB008040133A patent/CN1183082C/zh not_active Expired - Fee Related
- 2000-02-17 CN CNA2006101002245A patent/CN1907938A/zh active Pending
- 2000-02-17 HU HU0200358A patent/HUP0200358A3/hu unknown
- 2000-02-17 KR KR1020017010357A patent/KR100666423B1/ko not_active Expired - Fee Related
-
2001
- 2001-08-07 ZA ZA200106500A patent/ZA200106500B/en unknown
- 2001-08-15 NO NO20013971A patent/NO20013971L/no not_active Application Discontinuation
-
2010
- 2010-05-20 JP JP2010116000A patent/JP5343925B2/ja not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |