[go: up one dir, main page]

HUP0002277A3 - Bicyclic amino-pyrazinone compounds, a process for their preparation and pharmaceutical compositions containing them - Google Patents

Bicyclic amino-pyrazinone compounds, a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
HUP0002277A3
HUP0002277A3 HU0002277A HUP0002277A HUP0002277A3 HU P0002277 A3 HUP0002277 A3 HU P0002277A3 HU 0002277 A HU0002277 A HU 0002277A HU P0002277 A HUP0002277 A HU P0002277A HU P0002277 A3 HUP0002277 A3 HU P0002277A3
Authority
HU
Hungary
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
bicyclic amino
pyrazinone compounds
Prior art date
Application number
HU0002277A
Other languages
English (en)
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of HU0002277D0 publication Critical patent/HU0002277D0/hu
Publication of HUP0002277A2 publication Critical patent/HUP0002277A2/hu
Publication of HUP0002277A3 publication Critical patent/HUP0002277A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU0002277A 1999-06-15 2000-06-15 Bicyclic amino-pyrazinone compounds, a process for their preparation and pharmaceutical compositions containing them HUP0002277A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9907538A FR2795072B1 (fr) 1999-06-15 1999-06-15 Nouveaux derives bicycliques d'amino-pyrazinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (3)

Publication Number Publication Date
HU0002277D0 HU0002277D0 (en) 2000-08-28
HUP0002277A2 HUP0002277A2 (hu) 2001-05-28
HUP0002277A3 true HUP0002277A3 (en) 2002-12-28

Family

ID=9546789

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0002277A HUP0002277A3 (en) 1999-06-15 2000-06-15 Bicyclic amino-pyrazinone compounds, a process for their preparation and pharmaceutical compositions containing them

Country Status (22)

Country Link
US (1) US6277851B1 (hu)
EP (1) EP1069132B1 (hu)
JP (1) JP3364472B2 (hu)
KR (1) KR100456796B1 (hu)
CN (1) CN1147489C (hu)
AT (1) ATE251177T1 (hu)
AU (1) AU766194B2 (hu)
BR (1) BR0002643A (hu)
CA (1) CA2312206C (hu)
DE (1) DE60005609T2 (hu)
DK (1) DK1069132T3 (hu)
EA (1) EA003209B1 (hu)
ES (1) ES2208239T3 (hu)
FR (1) FR2795072B1 (hu)
HU (1) HUP0002277A3 (hu)
NO (1) NO316650B1 (hu)
NZ (1) NZ505149A (hu)
PL (1) PL199522B1 (hu)
PT (1) PT1069132E (hu)
SE (1) SE1069132T5 (hu)
SI (1) SI1069132T1 (hu)
ZA (1) ZA200003034B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001064678A2 (en) * 2000-02-29 2001-09-07 Bristol-Myers Squibb Pharma Company Inhibitors of hepatitis c virus ns3 protease
FR2818277B1 (fr) * 2000-12-14 2003-01-24 Servier Lab Nouveaux derives bicycliques d'amino-pyrazinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2004002405A2 (en) * 2002-06-26 2004-01-08 Bristol-Myers Squibb Company Amino-bicyclic pyrazinones and pyridinones
FR2867780B1 (fr) * 2004-03-19 2006-05-19 Servier Lab Nouveaux derives de 4-oxo-4,6,7,8-tetrahydropyrrolo (1,2-a) pyrazine-6-carboxamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US20140350034A1 (en) * 2012-01-27 2014-11-27 Novartis Ag Aminopyridine derivatives as plasma kallikrein inhibitors
WO2025076476A2 (en) * 2023-10-06 2025-04-10 Omeros Corporation Masp-2 inhibitors and methods of use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05117276A (ja) * 1991-10-23 1993-05-14 Sumitomo Pharmaceut Co Ltd 新規な３環性キノキサリンジオン誘導体
SK83897A3 (en) * 1994-12-22 1998-05-06 Iaf Biochem Int Low molecular weight bicyclic thrombin inhibitors
WO1996030396A1 (en) * 1995-03-24 1996-10-03 Molecumetics Ltd. β-SHEET MIMETICS AND USE THEREOF AS PROTEASE INHIBITORS
WO1997030708A1 (en) * 1996-02-22 1997-08-28 Merck & Co., Inc. Pyridinone thrombin inhibitors
AU3232597A (en) * 1996-06-18 1998-01-07 Warner-Lambert Company Pyrrolo{1,2-a}pyrazine-1,4-dione serine protease inhibitors
WO1998009987A1 (en) * 1996-09-06 1998-03-12 Biochem Pharma, Inc. Lactam inhibitors of thrombin
WO1998017274A1 (en) * 1996-10-24 1998-04-30 Merck & Co., Inc. Thrombin inhibitors
US5792779A (en) * 1997-02-19 1998-08-11 Merck & Co., Inc. Pyridinone thrombin inhibitors
EP1017383A4 (en) * 1997-09-23 2001-11-28 Merck & Co Inc THROMBINE INHIBITORS

Also Published As

Publication number Publication date
CN1277198A (zh) 2000-12-20
ATE251177T1 (de) 2003-10-15
HU0002277D0 (en) 2000-08-28
NO316650B1 (no) 2004-03-22
ES2208239T3 (es) 2004-06-16
NO20002941L (no) 2000-12-18
CA2312206A1 (fr) 2000-12-15
HK1032236A1 (en) 2001-07-13
FR2795072B1 (fr) 2001-07-27
EA200000527A2 (ru) 2000-12-25
SI1069132T1 (en) 2003-12-31
KR20010066846A (ko) 2001-07-11
SE1069132T5 (sv) 2004-01-07
ZA200003034B (en) 2001-01-11
DE60005609T2 (de) 2004-08-05
FR2795072A1 (fr) 2000-12-22
DE60005609D1 (de) 2003-11-06
KR100456796B1 (ko) 2004-11-10
PL199522B1 (pl) 2008-09-30
US6277851B1 (en) 2001-08-21
NZ505149A (en) 2001-01-26
SE1069132T3 (sv) 2003-12-09
AU766194B2 (en) 2003-10-09
DK1069132T3 (da) 2004-02-02
BR0002643A (pt) 2001-01-02
JP2001026592A (ja) 2001-01-30
HUP0002277A2 (hu) 2001-05-28
PL340784A1 (en) 2000-12-18
EP1069132B1 (fr) 2003-10-01
NO20002941D0 (no) 2000-06-08
EP1069132A1 (fr) 2001-01-17
CA2312206C (fr) 2004-07-06
EA200000527A3 (ru) 2001-04-23
JP3364472B2 (ja) 2003-01-08
PT1069132E (pt) 2004-02-27
AU4086500A (en) 2000-12-21
CN1147489C (zh) 2004-04-28
EA003209B1 (ru) 2003-02-27

Similar Documents

Publication Publication Date Title
HUP0203107A3 (en) Novel spiro compounds, process for their preparation and pharmaceutical compositions containing them
HUP0002843A3 (en) New betha-carboline compounds, a process for their preparation and pharmaceutical compositions containing them
HUP0203052A3 (en) Bicyclic imidazo-3-yl-amine derivatives, process for their preparation, pharmaceutical compositions containing them and their use
PL350522A1 (en) Bicyclic heterocycles, pharmaceutical compositions containing these compounds, and processes for preparing them
HUP0203316A3 (en) Amino-triazolopyridine derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0201122A3 (en) Pyrimidinone compounds, process for their preparation and pharmaceutical compositions containing them
HUP0203136A3 (en) Piperazine compounds, process for their preparation, pharmaceutical compositions containing them and their use
HUP0203766A3 (en) 5-pyridyl-1,3-azole compounds, process for producing the same and use thereof and pharmaceutical compositions containing them
HUP0203183A3 (en) Novel heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use
HUP0202731A3 (en) O-anisamide derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0201206A3 (en) Antibacterial compounds, process for their preparation and pharmaceutical compositions containing them
HUP0105108A3 (en) Amide compounds, process for their preparation and pharmaceutical compositions containing them
HUP0203140A3 (en) Bicyclic imidazo-5-yl-amine derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0201516A3 (en) 13-methyl-erythromycin derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0201753A3 (en) Pyridopyranoazepine derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0201402A3 (en) Bis-sulfonamides, process for their preparation and pharmaceutical compositions containing them
HUP0203184A3 (en) Isoxazolecarboxamide derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0001961A3 (en) Substituted dimeric compounds, a process for their preparation and pharmaceutical compositions contaning them
HU0100489D0 (en) New piperidine-4-sulphonamide compounds, process for their preparation and pharmaceutical compositions containing them
HUP0203471A3 (en) Antithrombotic compound, process for their preparation, pharmaceutical compositions containing them and their use
HUP0104272A3 (en) New cyclobutendione compounds, a process for their preparation and pharmaceutical compositions containing them
HUP0202379A3 (en) New compounds, process for producing them and pharmaceutical compositions containing them
HUP0105328A3 (en) Bicyclic amino-pirazinone compounds, a process for their preparation and pharmaceutical compositions containing them
HUP0200376A3 (en) Thiaoloindolinone compounds, process for their preparation and pharmaceutical composions containing them and their use
HUP0002277A3 (en) Bicyclic amino-pyrazinone compounds, a process for their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished