HUP0400545A3 - 1,4-disubstituted piperazine derivatives useful as uro-selectives alpha1-adrenoceptor blockers, and pharmaceutical compositions containing them - Google Patents

1,4-disubstituted piperazine derivatives useful as uro-selectives alpha1-adrenoceptor blockers, and pharmaceutical compositions containing them

Info

Publication number: HUP0400545A3
Authority: HU; Hungary
Prior art keywords: selectives; uro; alpha1; pharmaceutical compositions; compositions containing
Prior art date: 2000-11-30

Application number

HU0400545A

Other languages

English (en)

Original Assignee

Ranbaxy Lab Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-30

Filing date

2001-11-29

Publication date

2007-05-02

2001-11-29 Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd

2004-07-28 Publication of HUP0400545A2 publication Critical patent/HUP0400545A2/hu

2007-05-02 Publication of HUP0400545A3 publication Critical patent/HUP0400545A3/hu

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)

HU0400545A 2000-11-30 2001-11-29 1,4-disubstituted piperazine derivatives useful as uro-selectives alpha1-adrenoceptor blockers, and pharmaceutical compositions containing them HUP0400545A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IN1097DE2000		2000-11-30
PCT/IB2001/002261 WO2002044151A1 (en)	2000-11-30	2001-11-29	1,4-disubstituted piperazine derivatives useful as uro-selective $g(a)1-adrenoceptor blockers

Publications (2)

Publication Number	Publication Date
HUP0400545A2 HUP0400545A2 (hu)	2004-07-28
HUP0400545A3 true HUP0400545A3 (en)	2007-05-02

Family

ID=11097130

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0400545A HUP0400545A3 (en)	2000-11-30	2001-11-29	1,4-disubstituted piperazine derivatives useful as uro-selectives alpha1-adrenoceptor blockers, and pharmaceutical compositions containing them

Country Status (25)

Country	Link
US (1)	US6914064B2 (hu)
EP (1)	EP1339682A1 (hu)
JP (1)	JP2004514711A (hu)
KR (1)	KR20030068164A (hu)
CN (1)	CN1230423C (hu)
AP (1)	AP2003002810A0 (hu)
AR (1)	AR035930A1 (hu)
AU (2)	AU2231502A (hu)
BG (1)	BG107943A (hu)
BR (1)	BR0115865A (hu)
CA (1)	CA2430343A1 (hu)
CZ (1)	CZ20031698A3 (hu)
DO (1)	DOP2001000296A (hu)
EA (1)	EA006941B1 (hu)
EE (1)	EE200300250A (hu)
HU (1)	HUP0400545A3 (hu)
MA (1)	MA26064A1 (hu)
MX (1)	MXPA03004850A (hu)
NZ (1)	NZ526226A (hu)
OA (1)	OA12537A (hu)
PA (1)	PA8534001A1 (hu)
PL (1)	PL362210A1 (hu)
SK (1)	SK8052003A3 (hu)
WO (1)	WO2002044151A1 (hu)
ZA (1)	ZA200304242B (hu)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2481888A1 (en) *	2002-04-08	2003-10-16	Ranbaxy Laboratories Limited	Alpha, omega-dicarboximide derivatives as useful uro-selective a1a adrenoceptor blockers
AU2003278403A1 (en) *	2003-10-15	2005-05-05	Ranbaxy Laboratories Limited	1-alkylpiperazinyl-pyrrolidin-2, 5-dione derivatives as adrenergic receptor antagonist
WO2005092341A1 (en) *	2004-03-22	2005-10-06	Ranbaxy Laboratories Limited	Combination therapy for lower urinary tract symptoms
WO2005113498A1 (en) *	2004-05-19	2005-12-01	Ranbaxy Laboratories Limited	Adrenergic receptor antagonists
US20090312344A1 (en) *	2004-05-31	2009-12-17	Mohammad Salman	Arylpiperazine derivatives as adrenergic receptor antagonists
WO2006018815A1 (en) *	2004-08-16	2006-02-23	Ranbaxy Laboratories Limited	Piperazine derivatives as adrenergic receptor antagonists
WO2006051399A1 (en) *	2004-11-11	2006-05-18	Ranbaxy Laboratories Limited	Piperazine derivatives useful as adrenergic receptor antagonists
WO2006051374A2 (en) *	2004-11-11	2006-05-18	Ranbaxy Laboratories Limited	Arylpiperazines useful as adrenergic receptor antagonists
WO2006092710A1 (en) *	2005-03-02	2006-09-08	Ranbaxy Laboratories Limited	Metabolites of 2-{3-[4-(2-isopropoxyphenyl) piperazin-1-yl]-propyl}-3a,4,7,7a-tetrahydro-1h-isoindole-1,3-(2h)-dione
WO2006117760A1 (en) *	2005-05-03	2006-11-09	Ranbaxy Laboratories Limited	Adrenergic receptor antagonists
WO2007029156A2 (en) *	2005-09-05	2007-03-15	Ranbaxy Laboratories Limited	Isoindoledione derivatives as adrenergic receptor antagonists
WO2007039809A1 (en) *	2005-10-05	2007-04-12	Ranbaxy Laboratories Limited	Metabolites of 2- {3-[4-(5-fluoro-2-isopropoxy-phenyl)-piperazin-1-yl]-propyl} -5,6-dihydroxy-hexahydro-isoindole-1,3-dione
US9227944B2 (en)	2008-10-10	2016-01-05	Institute Of Pharmacology And Toxicology Academy Of Military Science P.L.A. China	Dopamine D3 receptor ligands and preparation and medical uses of the same
CN102264733B (zh)	2008-10-10	2014-07-30	中国人民解放军军事医学科学院毒物药物研究所	新型多巴胺d3受体配体，其制备方法及其医药用途
SG10201402054UA (en)	2009-05-05	2014-09-26	Muthiah Manoharan	Lipid compositions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS57197265A (en) *	1981-05-29	1982-12-03	Eisai Co Ltd	Carboxylic acid imide derivative, its preparation and medicament containing the same
JPS5936661A (ja) *	1982-08-26	1984-02-28	Eisai Co Ltd	カルボン酸イミド誘導体およびその製造方法ならびにそれを含有する医薬
JPS5976059A (ja) *	1982-10-21	1984-04-28	Sumitomo Chem Co Ltd	環状イミド誘導体及びその酸付加塩
JPS5995267A (ja) *	1982-11-25	1984-06-01	Eisai Co Ltd	カルボン酸イミド誘導体およびその製造方法
US4524206A (en) *	1983-09-12	1985-06-18	Mead Johnson & Company	1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
AT387773B (de) *	1983-09-12	1989-03-10	Bristol Myers Co	Verfahren zur herstellung von 1-heteroaryl-4-((2,5-pyrrolidindion-1-yl)aklyl) iperazin-derivaten
JPS60204784A (ja)	1984-03-29	1985-10-16	Eisai Co Ltd	カルボン酸イミド誘導体
JP2918899B2 (ja)	1989-03-09	1999-07-12	住友製薬株式会社	環状イミド誘導体の製造方法
US5688795A (en) *	1994-11-08	1997-11-18	Syntex (U.S.A.) Inc.	3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists
DE69612698T2 (de) *	1995-06-09	2001-12-06	F. Hoffmann-La Roche Ag, Basel	Pyrimidindion-, Pyrimidintrion-, Triazindion-Derivate als alpha-1-adrenergische Rezeptorantagonisten
AU6230698A (en)	1997-02-26	1998-09-18	Sumitomo Pharmaceuticals Company, Limited	Dopamine d4 receptor antagonist
HUP0100048A3 (en) *	1997-05-12	2002-12-28	Ortho Mcneil Pharm Inc	Arylsubstituted piperazine-derivatives, useful in the treatement of benign prostatic hyperlasia use of them for producing pharmaceutical compositions and pharmaceutical compositions containing them
US6083950A (en) *	1997-11-13	2000-07-04	Ranbaxy Laboratories Limited	1-(4-arylpiperazin-1-yl)-ω-[n-(α,ω-dicarboximido)]-alka nes useful as uro-selective α1-adrenoceptor blockers

2001
- 2001-11-29 EE EEP200300250A patent/EE200300250A/xx unknown
- 2001-11-29 HU HU0400545A patent/HUP0400545A3/hu unknown
- 2001-11-29 KR KR10-2003-7007305A patent/KR20030068164A/ko not_active Withdrawn
- 2001-11-29 CA CA002430343A patent/CA2430343A1/en not_active Abandoned
- 2001-11-29 EP EP01998540A patent/EP1339682A1/en not_active Withdrawn
- 2001-11-29 PL PL01362210A patent/PL362210A1/xx not_active Application Discontinuation
- 2001-11-29 BR BR0115865-1A patent/BR0115865A/pt not_active IP Right Cessation
- 2001-11-29 MX MXPA03004850A patent/MXPA03004850A/es unknown
- 2001-11-29 WO PCT/IB2001/002261 patent/WO2002044151A1/en not_active Ceased
- 2001-11-29 JP JP2002546521A patent/JP2004514711A/ja not_active Withdrawn
- 2001-11-29 AU AU2231502A patent/AU2231502A/xx active Pending
- 2001-11-29 AP APAP/P/2003/002810A patent/AP2003002810A0/en unknown
- 2001-11-29 CZ CZ20031698A patent/CZ20031698A3/cs unknown
- 2001-11-29 SK SK805-2003A patent/SK8052003A3/sk not_active Application Discontinuation
- 2001-11-29 NZ NZ526226A patent/NZ526226A/en unknown
- 2001-11-29 AU AU2002222315A patent/AU2002222315B2/en not_active Ceased
- 2001-11-29 OA OA1200300149A patent/OA12537A/en unknown
- 2001-11-29 CN CNB018220460A patent/CN1230423C/zh not_active Expired - Fee Related
- 2001-11-29 EA EA200300620A patent/EA006941B1/ru not_active IP Right Cessation
- 2001-11-29 PA PA20018534001A patent/PA8534001A1/es unknown
- 2001-11-30 US US09/998,115 patent/US6914064B2/en not_active Expired - Fee Related
- 2001-11-30 AR ARP010105588A patent/AR035930A1/es not_active Application Discontinuation
- 2001-11-30 DO DO2001000296A patent/DOP2001000296A/es unknown
2003
- 2003-05-30 MA MA27188A patent/MA26064A1/fr unknown
- 2003-05-30 ZA ZA200304242A patent/ZA200304242B/en unknown
- 2003-06-25 BG BG107943A patent/BG107943A/bg unknown

Also Published As

Publication number	Publication date
AP2003002810A0 (en)	2003-06-30
ZA200304242B (en)	2004-03-02
NZ526226A (en)	2004-05-28
AU2002222315B2 (en)	2007-06-21
PL362210A1 (en)	2004-10-18
CN1230423C (zh)	2005-12-07
JP2004514711A (ja)	2004-05-20
CN1486300A (zh)	2004-03-31
DOP2001000296A (es)	2003-03-15
US20020156085A1 (en)	2002-10-24
US6914064B2 (en)	2005-07-05
HUP0400545A2 (hu)	2004-07-28
MXPA03004850A (es)	2004-01-26
AR035930A1 (es)	2004-07-28
CZ20031698A3 (cs)	2003-11-12
BR0115865A (pt)	2003-12-23
EP1339682A1 (en)	2003-09-03
EA006941B1 (ru)	2006-06-30
OA12537A (en)	2006-06-05
SK8052003A3 (en)	2003-12-02
WO2002044151A1 (en)	2002-06-06
AU2231502A (en)	2002-06-11
EA200300620A1 (ru)	2003-12-25
EE200300250A (et)	2003-10-15
BG107943A (bg)	2004-08-31
KR20030068164A (ko)	2003-08-19
CA2430343A1 (en)	2002-06-06
PA8534001A1 (es)	2002-12-11
MA26064A1 (fr)	2004-04-01

Publication	Publication Date	Title
IL152718A0 (en)	2003-06-24	Piperidine derivatives and pharmaceutical compositions containing the same
HUP0303835A3 (en)	2009-08-28	Anti-allergic piperidine compounds, their use and pharmaceutical compositions containing them
DZ3311A1 (fr)	2001-09-07	Compositions pharmaceutiques contenant des derives de 3-amino-azetidine, les nouveaux derives et leur preparation
HUP0300203A3 (en)	2006-01-30	Novel cyclic amide derivatives, and pharmaceutical compositions containing same
IL157029A0 (en)	2004-02-08	Azaindoleoxoacetic piperazine derivatives and pharmaceutical compositions containing the same
IL151923A0 (en)	2003-04-10	Novel piperazine derivatives
HUP0301391A3 (en)	2010-03-29	Piperazine and piperidine derivatives pharmaceutical compositions containing them and their use
HUP0400636A3 (en)	2004-09-28	Pharmaceutical compositions containing azetidine derivatives, novel azetidine derivatives and preparation thereof
HUP0300207A3 (en)	2005-07-28	1,2,3,4-tetrahydroisquinoline derivatives, pharmaceutical compositions containing them and their preparation processes
EP1194120A4 (en)	2005-06-15	TRANSPARENT PHARMACEUTICAL COMPOSITIONS CONTAINING OIL
IL152451A0 (en)	2003-05-29	2-chloro-2-nitrophenylcarboxamide derivatives and pharmaceutical compositions containing the same
HUP0301178A3 (en)	2009-08-28	Glucopyranosyloxybenzylbenzene derivatives and pharmaceutical compositions containing the same
IL153123A0 (en)	2003-06-24	N-ureidoheterocycloalkyl-piperidine derivatives and pharmaceutical compositions containing the same
DZ3313A1 (fr)	2001-09-07	Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant
IL155841A0 (en)	2003-12-23	Heterocyclylalkyl piperidine derivatives, their preparation and compositions containing same
HUP0400551A2 (en)	2006-02-28	Piperazine derivatives, their preparation and pharmaceutical compositions containing them
IL158898A0 (en)	2004-05-12	PHARMACEUTICAL COMPOSITIONS CONTAINING APOMORPHINE, 6aR-(-)-N-PROPYL-NORAPOMORPHINE AND DERIVATIVES THEREOF
HUP9904167A3 (en)	2000-07-28	1,4-disubstituted piperazine and piperidine derivatives, their use and pharmaceutical compositions containing the same
PL355654A1 (en)	2004-05-04	Piperidine and piperazine derivatives which function as 5-ht2a
HUP0400545A3 (en)	2007-05-02	1,4-disubstituted piperazine derivatives useful as uro-selectives alpha1-adrenoceptor blockers, and pharmaceutical compositions containing them
IL161430A0 (en)	2004-09-27	Pharmaceutical compositions containing ecteinascidin 743
HUP0401403A3 (en)	2005-11-28	2,4-diaminothiazole derivatives, their use and pharmaceutical compositions containing them
IL153363A0 (en)	2003-07-06	Pharmaceutical compositions containing propenone derivatives
HUP0301442A3 (en)	2007-03-28	Bridged piperazine derivatives and pharmaceutical compositions containing them
HUP0203722A3 (en)	2005-03-29	Substituted phenyl-piperazine derivatives, pharmaceutical compositions containing them and their use

Legal Events

Date	Code	Title	Description
2006-10-30	HC9A	Change of name, address	Owner name: RANBAXY LABORATORIES LIMITED, IN Free format text: FORMER OWNER(S): RANBAXY LABORATORIES LIMITED, IN
2008-02-28	FA9A	Lapse of provisional patent protection due to relinquishment or protection considered relinquished

Date

Code

Title

Description

2006-10-30

HC9A

Change of name, address

Owner name: RANBAXY LABORATORIES LIMITED, IN

Free format text: FORMER OWNER(S): RANBAXY LABORATORIES LIMITED, IN

2008-02-28

FA9A

Lapse of provisional patent protection due to relinquishment or protection considered relinquished