[go: up one dir, main page]

EE200300250A - 1,4-diasendatud piperasiini derivaadid, mis on kasulikud uroselektiivsete alfa1-adrenoretseptorite blokaatoritena - Google Patents

1,4-diasendatud piperasiini derivaadid, mis on kasulikud uroselektiivsete alfa1-adrenoretseptorite blokaatoritena

Info

Publication number
EE200300250A
EE200300250A EEP200300250A EEP200300250A EE200300250A EE 200300250 A EE200300250 A EE 200300250A EE P200300250 A EEP200300250 A EE P200300250A EE P200300250 A EEP200300250 A EE P200300250A EE 200300250 A EE200300250 A EE 200300250A
Authority
EE
Estonia
Prior art keywords
uroselective
alpha1
derivatives useful
piperazine derivatives
disubstituted piperazine
Prior art date
Application number
EEP200300250A
Other languages
English (en)
Estonian (et)
Inventor
Anand Nitya
Jain Sanjay
Sinha Neelima
Chugh Anita
G. Hegde Laxminarayan
Bahadur Gupta Jang
Original Assignee
Ranbaxy Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Limited filed Critical Ranbaxy Laboratories Limited
Publication of EE200300250A publication Critical patent/EE200300250A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
EEP200300250A 2000-11-30 2001-11-29 1,4-diasendatud piperasiini derivaadid, mis on kasulikud uroselektiivsete alfa1-adrenoretseptorite blokaatoritena EE200300250A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1097DE2000 2000-11-30
PCT/IB2001/002261 WO2002044151A1 (en) 2000-11-30 2001-11-29 1,4-disubstituted piperazine derivatives useful as uro-selective $g(a)1-adrenoceptor blockers

Publications (1)

Publication Number Publication Date
EE200300250A true EE200300250A (et) 2003-10-15

Family

ID=11097130

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300250A EE200300250A (et) 2000-11-30 2001-11-29 1,4-diasendatud piperasiini derivaadid, mis on kasulikud uroselektiivsete alfa1-adrenoretseptorite blokaatoritena

Country Status (25)

Country Link
US (1) US6914064B2 (xx)
EP (1) EP1339682A1 (xx)
JP (1) JP2004514711A (xx)
KR (1) KR20030068164A (xx)
CN (1) CN1230423C (xx)
AP (1) AP2003002810A0 (xx)
AR (1) AR035930A1 (xx)
AU (2) AU2231502A (xx)
BG (1) BG107943A (xx)
BR (1) BR0115865A (xx)
CA (1) CA2430343A1 (xx)
CZ (1) CZ20031698A3 (xx)
DO (1) DOP2001000296A (xx)
EA (1) EA006941B1 (xx)
EE (1) EE200300250A (xx)
HU (1) HUP0400545A3 (xx)
MA (1) MA26064A1 (xx)
MX (1) MXPA03004850A (xx)
NZ (1) NZ526226A (xx)
OA (1) OA12537A (xx)
PA (1) PA8534001A1 (xx)
PL (1) PL362210A1 (xx)
SK (1) SK8052003A3 (xx)
WO (1) WO2002044151A1 (xx)
ZA (1) ZA200304242B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2481888A1 (en) * 2002-04-08 2003-10-16 Ranbaxy Laboratories Limited Alpha, omega-dicarboximide derivatives as useful uro-selective a1a adrenoceptor blockers
AU2003278403A1 (en) * 2003-10-15 2005-05-05 Ranbaxy Laboratories Limited 1-alkylpiperazinyl-pyrrolidin-2, 5-dione derivatives as adrenergic receptor antagonist
WO2005092341A1 (en) * 2004-03-22 2005-10-06 Ranbaxy Laboratories Limited Combination therapy for lower urinary tract symptoms
WO2005113498A1 (en) * 2004-05-19 2005-12-01 Ranbaxy Laboratories Limited Adrenergic receptor antagonists
US20090312344A1 (en) * 2004-05-31 2009-12-17 Mohammad Salman Arylpiperazine derivatives as adrenergic receptor antagonists
WO2006018815A1 (en) * 2004-08-16 2006-02-23 Ranbaxy Laboratories Limited Piperazine derivatives as adrenergic receptor antagonists
WO2006051399A1 (en) * 2004-11-11 2006-05-18 Ranbaxy Laboratories Limited Piperazine derivatives useful as adrenergic receptor antagonists
WO2006051374A2 (en) * 2004-11-11 2006-05-18 Ranbaxy Laboratories Limited Arylpiperazines useful as adrenergic receptor antagonists
WO2006092710A1 (en) * 2005-03-02 2006-09-08 Ranbaxy Laboratories Limited Metabolites of 2-{3-[4-(2-isopropoxyphenyl) piperazin-1-yl]-propyl}-3a,4,7,7a-tetrahydro-1h-isoindole-1,3-(2h)-dione
WO2006117760A1 (en) * 2005-05-03 2006-11-09 Ranbaxy Laboratories Limited Adrenergic receptor antagonists
WO2007029156A2 (en) * 2005-09-05 2007-03-15 Ranbaxy Laboratories Limited Isoindoledione derivatives as adrenergic receptor antagonists
WO2007039809A1 (en) * 2005-10-05 2007-04-12 Ranbaxy Laboratories Limited Metabolites of 2- {3-[4-(5-fluoro-2-isopropoxy-phenyl)-piperazin-1-yl]-propyl} -5,6-dihydroxy-hexahydro-isoindole-1,3-dione
US9227944B2 (en) 2008-10-10 2016-01-05 Institute Of Pharmacology And Toxicology Academy Of Military Science P.L.A. China Dopamine D3 receptor ligands and preparation and medical uses of the same
CN102264733B (zh) 2008-10-10 2014-07-30 中国人民解放军军事医学科学院毒物药物研究所 新型多巴胺d3受体配体，其制备方法及其医药用途
SG10201402054UA (en) 2009-05-05 2014-09-26 Muthiah Manoharan Lipid compositions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57197265A (en) * 1981-05-29 1982-12-03 Eisai Co Ltd Carboxylic acid imide derivative, its preparation and medicament containing the same
JPS5936661A (ja) * 1982-08-26 1984-02-28 Eisai Co Ltd カルボン酸イミド誘導体およびその製造方法ならびにそれを含有する医薬
JPS5976059A (ja) * 1982-10-21 1984-04-28 Sumitomo Chem Co Ltd 環状イミド誘導体及びその酸付加塩
JPS5995267A (ja) * 1982-11-25 1984-06-01 Eisai Co Ltd カルボン酸イミド誘導体およびその製造方法
US4524206A (en) * 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
AT387773B (de) * 1983-09-12 1989-03-10 Bristol Myers Co Verfahren zur herstellung von 1-heteroaryl-4-((2,5-pyrrolidindion-1-yl)aklyl) iperazin-derivaten
JPS60204784A (ja) 1984-03-29 1985-10-16 Eisai Co Ltd カルボン酸イミド誘導体
JP2918899B2 (ja) 1989-03-09 1999-07-12 住友製薬株式会社 環状イミド誘導体の製造方法
US5688795A (en) * 1994-11-08 1997-11-18 Syntex (U.S.A.) Inc. 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists
DE69612698T2 (de) * 1995-06-09 2001-12-06 F. Hoffmann-La Roche Ag, Basel Pyrimidindion-, Pyrimidintrion-, Triazindion-Derivate als alpha-1-adrenergische Rezeptorantagonisten
AU6230698A (en) 1997-02-26 1998-09-18 Sumitomo Pharmaceuticals Company, Limited Dopamine d4 receptor antagonist
HUP0100048A3 (en) * 1997-05-12 2002-12-28 Ortho Mcneil Pharm Inc Arylsubstituted piperazine-derivatives, useful in the treatement of benign prostatic hyperlasia use of them for producing pharmaceutical compositions and pharmaceutical compositions containing them
US6083950A (en) * 1997-11-13 2000-07-04 Ranbaxy Laboratories Limited 1-(4-arylpiperazin-1-yl)-ω-[n-(α,ω-dicarboximido)]-alka nes useful as uro-selective α1-adrenoceptor blockers

Also Published As

Publication number Publication date
AP2003002810A0 (en) 2003-06-30
ZA200304242B (en) 2004-03-02
NZ526226A (en) 2004-05-28
AU2002222315B2 (en) 2007-06-21
PL362210A1 (en) 2004-10-18
CN1230423C (zh) 2005-12-07
JP2004514711A (ja) 2004-05-20
HUP0400545A3 (en) 2007-05-02
CN1486300A (zh) 2004-03-31
DOP2001000296A (es) 2003-03-15
US20020156085A1 (en) 2002-10-24
US6914064B2 (en) 2005-07-05
HUP0400545A2 (hu) 2004-07-28
MXPA03004850A (es) 2004-01-26
AR035930A1 (es) 2004-07-28
CZ20031698A3 (cs) 2003-11-12
BR0115865A (pt) 2003-12-23
EP1339682A1 (en) 2003-09-03
EA006941B1 (ru) 2006-06-30
OA12537A (en) 2006-06-05
SK8052003A3 (en) 2003-12-02
WO2002044151A1 (en) 2002-06-06
AU2231502A (en) 2002-06-11
EA200300620A1 (ru) 2003-12-25
BG107943A (bg) 2004-08-31
KR20030068164A (ko) 2003-08-19
CA2430343A1 (en) 2002-06-06
PA8534001A1 (es) 2002-12-11
MA26064A1 (fr) 2004-04-01

Similar Documents

Publication Publication Date Title
ATE414079T1 (de) 2,4-disubstituierte thiazolyl derivate
DE60131971D1 (de) 1,3,8-TRIAZA-SPIROi4,5 DECAN-4-ONDERIVATIVE ALS NEUROKININREZEPTORANTAGONISTEN
ATE397595T1 (de) Piperazin-derivate
DE60019577D1 (de) 4, 5, 6, 7-tetrahydroindazolderivate als antitumormittel
EE200200567A (et) Uued piperasiini derivaadid
DK1325008T3 (da) Piperazinderivater
ATE363463T1 (de) 2-(2,6-dichlorphenyl)-diarylimidazole
NO20021459L (no) Piperazin-derivater som 5-HT1B-antagonister
NO20022557D0 (no) 2,4-diaminopyrimidinforbindelser nyttige som immunosuppreserende midler
EE200300250A (et) 1,4-diasendatud piperasiini derivaadid, mis on kasulikud uroselektiivsete alfa1-adrenoretseptorite blokaatoritena
AR028357A1 (es) 4-bencil-1-[2-(4-hidroxi-fenoxi)-etil]-piperidin-3,4-diol
IT1320120B1 (it) 2-(3,5-bis-trifluorometil-fenil)-n-metil-n-(6-morfolin-4-il-4-0-tolil-piridin-3-il) -isobutirrammide.
NO20031572L (no) Brodannete piperazinderivater
DE50107988D1 (de) Substituierte 1,2,3,4-tetrahydrochinolin-2-carbonsäurederivate
DE60025958D1 (de) 14,15-beta-methylen substituierte androgene
NO20023954L (no) Substituerte piperasinforbindelser
NO20030868L (no) N-(3,5-diklor-2-metoksyfenyl)-4-metoksy-3-piperazin-1-yl- benzensulfonamid
NO20042980L (no) 3,4-dihydro-1H-isokinolin-2-yl-derivater
NO20011934D0 (no) 2,4-disubstituerte triazinderivater
NO20044405L (no) Neurotensinaktive 2,3-diaryl-pyrazolidin derivater
ITMI20021328A1 (it) Nuove piperazine 1,4 - disostituite
IS7131A (is) Nýjar 2,4-díamínóþíasól afleiður
AR027974A1 (es) 1-aril-ciclopropilmetilamino-1,3,5-triazinas substituidas
DK1274687T3 (da) 1,2,3,4-tetrahydroisoquinolinderivater
IS7299A (is) 3,4-díhýdró-1H-ísókínólóín-2-ýl-afleiður