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HRP20031063A2 - New derivatives of oxazolidinones as antibacterial agents - Google Patents

New derivatives of oxazolidinones as antibacterial agents

Info

Publication number
HRP20031063A2
HRP20031063A2 HR20031063A HRP20031063A HRP20031063A2 HR P20031063 A2 HRP20031063 A2 HR P20031063A2 HR 20031063 A HR20031063 A HR 20031063A HR P20031063 A HRP20031063 A HR P20031063A HR P20031063 A2 HRP20031063 A2 HR P20031063A2
Authority
HR
Croatia
Prior art keywords
oxazolidinones
antibacterial agents
new derivatives
derivatives
new
Prior art date
Application number
HR20031063A
Other languages
English (en)
Inventor
Marisabel Mourelle Mancini
Juan Huguet Clotet
Jose Hidalgo Rodriguez
Juan Carlos Del Castillo
Original Assignee
Vita Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vita Lab filed Critical Vita Lab
Publication of HRP20031063A2 publication Critical patent/HRP20031063A2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HR20031063A 2001-06-27 2002-06-24 New derivatives of oxazolidinones as antibacterial agents HRP20031063A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200101559A ES2186550B2 (es) 2001-06-27 2001-06-27 Nuevos derivados de oxazolidinonas como antibacterianos.
PCT/IB2002/002408 WO2003002560A1 (en) 2001-06-27 2002-06-24 New derivatives of oxazolidinones as antibacterial agents

Publications (1)

Publication Number Publication Date
HRP20031063A2 true HRP20031063A2 (en) 2004-04-30

Family

ID=8498288

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20031063A HRP20031063A2 (en) 2001-06-27 2002-06-24 New derivatives of oxazolidinones as antibacterial agents

Country Status (29)

Country Link
US (1) US20040147545A1 (is)
EP (1) EP1401834A1 (is)
JP (1) JP2004521147A (is)
KR (1) KR20040030712A (is)
CN (1) CN1520412A (is)
AP (1) AP2003002942A0 (is)
AR (1) AR035254A1 (is)
BG (1) BG108498A (is)
BR (1) BR0210667A (is)
CA (1) CA2450982A1 (is)
CO (1) CO5540387A2 (is)
CR (1) CR7195A (is)
CZ (1) CZ2004101A3 (is)
EA (1) EA200400086A1 (is)
EE (1) EE200400004A (is)
ES (1) ES2186550B2 (is)
HR (1) HRP20031063A2 (is)
HU (1) HUP0400370A2 (is)
IL (1) IL159434A0 (is)
IS (1) IS7088A (is)
MA (1) MA27046A1 (is)
MX (1) MXPA04000185A (is)
NO (1) NO20035791L (is)
NZ (1) NZ530206A (is)
OA (1) OA12639A (is)
PE (1) PE20030134A1 (is)
PL (1) PL365476A1 (is)
SK (1) SK572004A3 (is)
WO (1) WO2003002560A1 (is)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003031443A1 (en) * 2001-10-04 2003-04-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety
BRPI0409955A (pt) 2003-04-30 2006-04-25 Morphochem Ag Komb Chemie uso de antibióticos hìbridos de oxazolidinona - quinolina para o tratamento de antrax e outras infecções
DE10340485B4 (de) 2003-09-03 2015-05-13 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
WO2005051933A1 (en) * 2003-11-28 2005-06-09 Ranbaxy Laboratories Limited An improved process for the synthesis of 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, a key intermediate for oxazolidinone antimicrobials and compounds prepared thereby
EP1557416A1 (en) * 2004-01-23 2005-07-27 Morphochem Aktiengesellschaft Für Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
US8158797B2 (en) 2003-12-18 2012-04-17 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
DK1709044T4 (da) * 2003-12-18 2014-01-20 Morphochem Ag Komb Chemie Oxazolidinon-quinolon-hybridantibiotika
US20060105941A1 (en) * 2004-11-12 2006-05-18 Allergan, Inc. Mixed antibiotic codrugs
TW200804358A (en) 2006-03-31 2008-01-16 Res Found Itsuu Lab Novel compound having heterocycle
EP2208729A4 (en) 2007-10-02 2011-04-27 Res Found Itsuu Lab OXAZOLIDINONE DERIVATIVE WITH 7-CHAIN HETEROCYCLE
SI2296651T1 (sl) * 2008-05-09 2012-10-30 Actelion Pharmaceuticals Ltd Derivati 5-hidroksimetil-oksazolidin-2-ona za zdravljenje bakterijskih ÄŤrevesnih bolezni
EP3003289B1 (en) 2013-05-28 2019-02-20 Morphochem Aktiengesellschaft für kombinatorische Chemie Administration of oxazolidinone-quinolone hybrid antibacterials
US9993469B2 (en) 2013-05-28 2018-06-12 Morphochem Aktiengesellschaft Für Kombinatorishe Chemie Combination therapy comprising oxazolidinone-quinolones for use in treating bacterial infections
CN107286111B (zh) * 2016-03-30 2020-06-19 广东赛法洛药业有限公司 一种噁唑烷酮化合物的制备方法
CN107286182A (zh) * 2016-04-12 2017-10-24 李靖 新型噁唑烷酮‑氟喹诺酮衍生物及用途
US10087171B2 (en) 2016-12-19 2018-10-02 Actelion Pharmaceuticals Ltd Crystalline forms of cadazolid
GB201708606D0 (en) * 2017-05-30 2017-07-12 King S College London Antibiotic resistance breakers
WO2019106693A1 (en) * 2017-11-29 2019-06-06 Bugworks Research India Pvt Ltd Anti-bacterial heterocyclic compounds and their synthesis
CN111087409B (zh) * 2018-10-24 2021-06-08 江阴安博生物医药有限公司 一种喹诺酮类化合物及其制备方法和应用
CN112940038A (zh) 2019-12-11 2021-06-11 华创合成制药股份有限公司 新型噁唑烷酮类化合物及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE444566B (sv) * 1977-09-20 1986-04-21 Bellon Labor Sa Roger 7-dialkylamin-6-halogen-4-oxo-1,4-dihydrokinolin-3-karboxylsyra, forfarande for framstellning derav och farmaceutiskt preparat derav
ATE123494T1 (de) * 1989-03-30 1995-06-15 Wakunaga Seiyaku Kk Chinolon-derivate und deren salze, verfahren zu deren herstellung und diese enthaltende antibakterielle wirkstoffe.
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
EP0788498B1 (en) * 1994-10-26 2001-08-16 PHARMACIA & UPJOHN COMPANY Phenyloxazolidinone antimicrobials
CZ238698A3 (cs) * 1996-01-31 1998-12-16 Sankyo Company, Limited Prostředky pro léčení a prevenci AIDS
US5837870A (en) * 1996-04-11 1998-11-17 Pharmacia & Upjohn Company Process to prepare oxazolidinones
GB9614236D0 (en) * 1996-07-06 1996-09-04 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
NO20035791L (no) 2004-02-19
PE20030134A1 (es) 2003-04-04
OA12639A (en) 2006-06-15
NZ530206A (en) 2005-07-29
ES2186550A1 (es) 2003-05-01
BG108498A (en) 2005-03-31
SK572004A3 (en) 2004-08-03
EA200400086A1 (ru) 2004-06-24
CN1520412A (zh) 2004-08-11
CZ2004101A3 (cs) 2004-07-14
IL159434A0 (en) 2004-06-01
CR7195A (es) 2004-03-05
US20040147545A1 (en) 2004-07-29
PL365476A1 (en) 2005-01-10
KR20040030712A (ko) 2004-04-09
IS7088A (is) 2003-12-22
JP2004521147A (ja) 2004-07-15
EP1401834A1 (en) 2004-03-31
ES2186550B2 (es) 2003-11-16
EE200400004A (et) 2004-02-16
MA27046A1 (fr) 2004-12-20
BR0210667A (pt) 2004-10-05
HUP0400370A2 (hu) 2004-08-30
CO5540387A2 (es) 2005-07-29
CA2450982A1 (en) 2003-01-09
AP2003002942A0 (en) 2003-12-24
WO2003002560A1 (en) 2003-01-09
AR035254A1 (es) 2004-05-05
MXPA04000185A (es) 2004-03-18

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
OBST Application withdrawn