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CR7195A - Nuevos derivados de oxazolidinonas como antibacterianos - Google Patents

Nuevos derivados de oxazolidinonas como antibacterianos

Info

Publication number
CR7195A
CR7195A CR7195A CR7195A CR7195A CR 7195 A CR7195 A CR 7195A CR 7195 A CR7195 A CR 7195A CR 7195 A CR7195 A CR 7195A CR 7195 A CR7195 A CR 7195A
Authority
CR
Costa Rica
Prior art keywords
antibacterials
oxazolidinones
new derivatives
derivatives
new
Prior art date
Application number
CR7195A
Other languages
English (en)
Inventor
Mourelle Manzini Marisabel
Huguet Clotet Juan
Hidalgo Rodriguez Jose
Carlos Del Castillo Juan
Original Assignee
Laboratoiros Vita S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoiros Vita S A filed Critical Laboratoiros Vita S A
Publication of CR7195A publication Critical patent/CR7195A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Proporciona nuevos derivados fluorquinologicos de oxazolidinosas de formula general (I) asi como procedimientos para su obtencion , las correspondientes composiciones farmaceuticas y su utilizacion para la fabricacion de un medicamento destinado al tratamiento de infecciones microbianas. Estos nuevos compuestos son utiles como antibacterianos.
CR7195A 2001-06-27 2003-12-10 Nuevos derivados de oxazolidinonas como antibacterianos CR7195A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200101559A ES2186550B2 (es) 2001-06-27 2001-06-27 Nuevos derivados de oxazolidinonas como antibacterianos.

Publications (1)

Publication Number Publication Date
CR7195A true CR7195A (es) 2004-03-05

Family

ID=8498288

Family Applications (1)

Application Number Title Priority Date Filing Date
CR7195A CR7195A (es) 2001-06-27 2003-12-10 Nuevos derivados de oxazolidinonas como antibacterianos

Country Status (29)

Country Link
US (1) US20040147545A1 (es)
EP (1) EP1401834A1 (es)
JP (1) JP2004521147A (es)
KR (1) KR20040030712A (es)
CN (1) CN1520412A (es)
AP (1) AP2003002942A0 (es)
AR (1) AR035254A1 (es)
BG (1) BG108498A (es)
BR (1) BR0210667A (es)
CA (1) CA2450982A1 (es)
CO (1) CO5540387A2 (es)
CR (1) CR7195A (es)
CZ (1) CZ2004101A3 (es)
EA (1) EA200400086A1 (es)
EE (1) EE200400004A (es)
ES (1) ES2186550B2 (es)
HR (1) HRP20031063A2 (es)
HU (1) HUP0400370A2 (es)
IL (1) IL159434A0 (es)
IS (1) IS7088A (es)
MA (1) MA27046A1 (es)
MX (1) MXPA04000185A (es)
NO (1) NO20035791L (es)
NZ (1) NZ530206A (es)
OA (1) OA12639A (es)
PE (1) PE20030134A1 (es)
PL (1) PL365476A1 (es)
SK (1) SK572004A3 (es)
WO (1) WO2003002560A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003031443A1 (en) * 2001-10-04 2003-04-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety
US20070155714A1 (en) * 2003-04-30 2007-07-05 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Use of oxazolidinone-quinoline hybrid antibiotics for the treatment of anthrax and other infections
DE10340485B4 (de) 2003-09-03 2015-05-13 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
WO2005051933A1 (en) * 2003-11-28 2005-06-09 Ranbaxy Laboratories Limited An improved process for the synthesis of 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, a key intermediate for oxazolidinone antimicrobials and compounds prepared thereby
EP1557416A1 (en) * 2004-01-23 2005-07-27 Morphochem Aktiengesellschaft Für Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
JP2007516263A (ja) 2003-12-18 2007-06-21 モルフォケム アクチェンゲゼルシャフト フュア コンビナトリシェ ヘミー オキサゾリジノン−キノロンハイブリッド抗生物質
US8158797B2 (en) 2003-12-18 2012-04-17 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
US20060105941A1 (en) * 2004-11-12 2006-05-18 Allergan, Inc. Mixed antibiotic codrugs
JP5161070B2 (ja) 2006-03-31 2013-03-13 財団法人乙卯研究所 ヘテロ環を有する新規化合物
US8530646B2 (en) 2007-10-02 2013-09-10 Research Foundation Itsuu Laboratory Oxazolidinone derivative having 7-membered hetero ring
MY156304A (en) * 2008-05-09 2016-01-29 Actelion Pharmaceuticals Ltd 5-hydroxymethyl-oxazolidin-2-one derivatives for treating bacterial intestinal diseases
HUE043786T2 (hu) 2013-05-28 2019-09-30 Morphochem Gmbh Oxazolidinon-kinolon hibrid antibakteriális hatóanyagok adagolása
KR102242998B1 (ko) 2013-05-28 2021-04-21 모르포켐 게엠베하 박테리아 감염 치료의 용도를 위한 옥사졸리디논-퀴놀론을 포함하는 병용 용법
CN107286111B (zh) * 2016-03-30 2020-06-19 广东赛法洛药业有限公司 一种噁唑烷酮化合物的制备方法
CN107286182A (zh) * 2016-04-12 2017-10-24 李靖 新型噁唑烷酮‑氟喹诺酮衍生物及用途
US10087171B2 (en) 2016-12-19 2018-10-02 Actelion Pharmaceuticals Ltd Crystalline forms of cadazolid
GB201708606D0 (en) * 2017-05-30 2017-07-12 King S College London Antibiotic resistance breakers
US11401277B2 (en) * 2017-11-29 2022-08-02 Bugworks Research, Inc. Anti-bacterial heterocyclic compounds and their synthesis
CN111087409B (zh) * 2018-10-24 2021-06-08 江阴安博生物医药有限公司 一种喹诺酮类化合物及其制备方法和应用
CN117567455A (zh) 2019-12-11 2024-02-20 华创合成制药股份有限公司 一种新型噁唑烷酮类化合物及其合成方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE444566B (sv) * 1977-09-20 1986-04-21 Bellon Labor Sa Roger 7-dialkylamin-6-halogen-4-oxo-1,4-dihydrokinolin-3-karboxylsyra, forfarande for framstellning derav och farmaceutiskt preparat derav
US5153203A (en) * 1989-03-30 1992-10-06 Wakunaga Seiyaku Kabushiki Kaisha Quinolone derivatives and salts thereof, preparation processes thereof, and antibacterial agents containing the same
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
PT788498E (pt) * 1994-10-26 2002-02-28 Upjohn Co Compostos antimicrobianos de feniloxazolidinona
CZ238698A3 (cs) * 1996-01-31 1998-12-16 Sankyo Company, Limited Prostředky pro léčení a prevenci AIDS
CZ298060B6 (cs) * 1996-04-11 2007-06-06 Pharmacia & Upjohn Company Zpusob prípravy oxazolidinonu
GB9614236D0 (en) * 1996-07-06 1996-09-04 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
BG108498A (en) 2005-03-31
AR035254A1 (es) 2004-05-05
CN1520412A (zh) 2004-08-11
NZ530206A (en) 2005-07-29
BR0210667A (pt) 2004-10-05
HUP0400370A2 (hu) 2004-08-30
AP2003002942A0 (en) 2003-12-24
MXPA04000185A (es) 2004-03-18
EA200400086A1 (ru) 2004-06-24
CA2450982A1 (en) 2003-01-09
IL159434A0 (en) 2004-06-01
ES2186550B2 (es) 2003-11-16
ES2186550A1 (es) 2003-05-01
KR20040030712A (ko) 2004-04-09
NO20035791L (no) 2004-02-19
PE20030134A1 (es) 2003-04-04
MA27046A1 (fr) 2004-12-20
EP1401834A1 (en) 2004-03-31
IS7088A (is) 2003-12-22
US20040147545A1 (en) 2004-07-29
PL365476A1 (en) 2005-01-10
OA12639A (en) 2006-06-15
CO5540387A2 (es) 2005-07-29
HRP20031063A2 (en) 2004-04-30
EE200400004A (et) 2004-02-16
WO2003002560A1 (en) 2003-01-09
JP2004521147A (ja) 2004-07-15
CZ2004101A3 (cs) 2004-07-14
SK572004A3 (en) 2004-08-03

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