HRP20020816A2 - Pyridazinyl phenyl hydrazones useful against congestive heart failure - Google Patents

Pyridazinyl phenyl hydrazones useful against congestive heart failure Download PDF

Info

Publication number: HRP20020816A2
Authority: HR; Croatia
Prior art keywords: methyl; phenyl; hydrogen; pyridazin; hydroxy
Prior art date: 2000-03-13

Application number

Other languages

English (en)

Croatian (hr)

Inventor

Jarmo Pystynen

Aino Pippuri

Anne Luiro

Pentti Nore

Reijo Bockstroem

Kari Loennberg

Heimo Haikala

Jouko Levijoki

Petri Kaheinen

Juha Kaivola

Original Assignee

Orion Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-13

Filing date

2001-03-12

Publication date

2004-12-31

2001-03-12 Application filed by Orion Corp filed Critical Orion Corp

2004-12-31 Publication of HRP20020816A2 publication Critical patent/HRP20020816A2/hr

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

HRP20020816 2000-03-13 2001-03-12 Pyridazinyl phenyl hydrazones useful against congestive heart failure HRP20020816A2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FI20000577A FI20000577A0 (fi)	2000-03-13	2000-03-13	Pyridatsinyylifenyylihydratsoneja
PCT/FI2001/000241 WO2001068611A1 (en)	2000-03-13	2001-03-12	Pyridazinyl phenyl hydrazones useful against congestive heart failure

Publications (1)

Publication Number	Publication Date
HRP20020816A2 true HRP20020816A2 (en)	2004-12-31

Family

ID=8557913

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HRP20020816 HRP20020816A2 (en)	2000-03-13	2001-03-12	Pyridazinyl phenyl hydrazones useful against congestive heart failure

Country Status (31)

Country	Link
US (1)	US6699868B2 (et)
EP (1)	EP1265871B1 (et)
JP (1)	JP2003527375A (et)
KR (1)	KR20030001379A (et)
CN (1)	CN1191241C (et)
AR (1)	AR027644A1 (et)
AT (1)	ATE317388T1 (et)
AU (2)	AU4657701A (et)
BG (1)	BG65859B1 (et)
BR (1)	BR0109136A (et)
CA (1)	CA2403188A1 (et)
CZ (1)	CZ20022997A3 (et)
DE (1)	DE60117131T2 (et)
DK (1)	DK1265871T3 (et)
EA (1)	EA005574B1 (et)
EE (1)	EE200200520A (et)
ES (1)	ES2256222T3 (et)
FI (1)	FI20000577A0 (et)
HR (1)	HRP20020816A2 (et)
HU (1)	HUP0300177A3 (et)
IL (2)	IL151492A0 (et)
MX (1)	MXPA02008997A (et)
NO (1)	NO324172B1 (et)
NZ (1)	NZ521162A (et)
PL (1)	PL357107A1 (et)
RS (1)	RS50439B (et)
SI (1)	SI1265871T1 (et)
SK (1)	SK287163B6 (et)
UA (1)	UA74571C2 (et)
WO (1)	WO2001068611A1 (et)
ZA (1)	ZA200206917B (et)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0015228D0 (en) *	2000-06-21	2000-08-16	Portela & Ca Sa	Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders
JP4561698B2 (ja) *	2002-02-19	2010-10-13	小野薬品工業株式会社	縮合ピリダジン誘導体化合物およびその化合物を有効成分として含有する薬剤
WO2004087641A1 (ja) *	2003-03-31	2004-10-14	Daiichi Pharmaceutical Co., Ltd.	ヒドラゾン誘導体
GB0503962D0 (en)	2005-02-25	2005-04-06	Kudos Pharm Ltd	Compounds
MX2009000884A (es)	2006-07-25	2009-06-05	Cephalon Inc	Derivados de piridizinona.
EP2117551A1 (en) *	2007-01-17	2009-11-18	Orion Corporation	Levosimendan for use in treating chronic valvular disease
US9447059B2 (en)	2011-09-27	2016-09-20	Zeon Corporation	Intermediate for manufacture of polymerizable compound and process for manufacture thereof
US9926282B2 (en) *	2013-01-18	2018-03-27	Bristol-Myers Squibb Company	Phthalazinones and isoquinolinones as rock inhibitors
EP3804707A4 (en) *	2018-06-08	2022-03-16	Nissan Chemical Corporation	KINASE INHIBITOR

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3531658A1 (de)	1985-09-05	1987-03-12	Boehringer Mannheim Gmbh	Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel
GB8903130D0 (en)	1989-02-11	1989-03-30	Orion Yhtymae Oy	Substituted pyridazinones
US5185332A (en) *	1989-02-11	1993-02-09	Orion-Yhtyma Oy	Thiadiazines and pharmaceutical compositions thereof as well as method of use
FI973804A7 (fi) *	1997-09-26	1999-03-27	Orion Yhtymae Oy	Levosimendaanin oraalisia koostumuksia

2000
- 2000-03-13 FI FI20000577A patent/FI20000577A0/fi unknown
2001
- 2001-03-12 PL PL01357107A patent/PL357107A1/xx not_active Application Discontinuation
- 2001-03-12 HU HU0300177A patent/HUP0300177A3/hu unknown
- 2001-03-12 CA CA002403188A patent/CA2403188A1/en not_active Abandoned
- 2001-03-12 ES ES01919489T patent/ES2256222T3/es not_active Expired - Lifetime
- 2001-03-12 IL IL15149201A patent/IL151492A0/xx active IP Right Grant
- 2001-03-12 DE DE60117131T patent/DE60117131T2/de not_active Expired - Fee Related
- 2001-03-12 MX MXPA02008997A patent/MXPA02008997A/es active IP Right Grant
- 2001-03-12 AU AU4657701A patent/AU4657701A/xx active Pending
- 2001-03-12 SK SK1288-2002A patent/SK287163B6/sk not_active IP Right Cessation
- 2001-03-12 KR KR1020027012066A patent/KR20030001379A/ko not_active Ceased
- 2001-03-12 EA EA200200973A patent/EA005574B1/ru not_active IP Right Cessation
- 2001-03-12 AT AT01919489T patent/ATE317388T1/de not_active IP Right Cessation
- 2001-03-12 CN CNB018065309A patent/CN1191241C/zh not_active Expired - Fee Related
- 2001-03-12 AR ARP010101149A patent/AR027644A1/es unknown
- 2001-03-12 DK DK01919489T patent/DK1265871T3/da active
- 2001-03-12 EE EEP200200520A patent/EE200200520A/et unknown
- 2001-03-12 AU AU2001246577A patent/AU2001246577B2/en not_active Ceased
- 2001-03-12 WO PCT/FI2001/000241 patent/WO2001068611A1/en not_active Ceased
- 2001-03-12 BR BR0109136-0A patent/BR0109136A/pt not_active IP Right Cessation
- 2001-03-12 CZ CZ20022997A patent/CZ20022997A3/cs unknown
- 2001-03-12 RS YUP-685/02A patent/RS50439B/sr unknown
- 2001-03-12 EP EP01919489A patent/EP1265871B1/en not_active Expired - Lifetime
- 2001-03-12 US US10/221,348 patent/US6699868B2/en not_active Expired - Fee Related
- 2001-03-12 HR HRP20020816 patent/HRP20020816A2/hr not_active Application Discontinuation
- 2001-03-12 NZ NZ521162A patent/NZ521162A/en unknown
- 2001-03-12 SI SI200130518T patent/SI1265871T1/sl unknown
- 2001-03-12 JP JP2001567705A patent/JP2003527375A/ja not_active Withdrawn
- 2001-12-03 UA UA2002108100A patent/UA74571C2/uk unknown
2002
- 2002-08-26 IL IL151492A patent/IL151492A/en not_active IP Right Cessation
- 2002-08-28 ZA ZA200206917A patent/ZA200206917B/en unknown
- 2002-09-05 NO NO20024247A patent/NO324172B1/no not_active IP Right Cessation
- 2002-10-08 BG BG107175A patent/BG65859B1/bg unknown

Also Published As

Publication number	Publication date
HUP0300177A3 (en)	2003-09-29
NO324172B1 (no)	2007-09-03
HUP0300177A2 (hu)	2003-07-28
EA200200973A1 (ru)	2003-02-27
YU68502A (sh)	2005-11-28
EA005574B1 (ru)	2005-04-28
NO20024247D0 (no)	2002-09-05
BR0109136A (pt)	2002-12-24
EP1265871A1 (en)	2002-12-18
IL151492A0 (en)	2003-04-10
HK1052008A1 (en)	2003-08-29
ES2256222T3 (es)	2006-07-16
SK12882002A3 (sk)	2003-06-03
NZ521162A (en)	2003-11-28
US6699868B2 (en)	2004-03-02
CA2403188A1 (en)	2001-09-20
PL357107A1 (en)	2004-07-12
DK1265871T3 (da)	2006-06-06
ATE317388T1 (de)	2006-02-15
DE60117131D1 (de)	2006-04-20
IL151492A (en)	2007-09-20
KR20030001379A (ko)	2003-01-06
US20030158200A1 (en)	2003-08-21
SI1265871T1 (sl)	2006-06-30
AU2001246577B2 (en)	2006-08-31
RS50439B (sr)	2009-12-31
NO20024247L (no)	2002-10-25
AU4657701A (en)	2001-09-24
CZ20022997A3 (cs)	2003-04-16
WO2001068611A1 (en)	2001-09-20
AR027644A1 (es)	2003-04-09
ZA200206917B (en)	2003-07-30
FI20000577A0 (fi)	2000-03-13
JP2003527375A (ja)	2003-09-16
CN1418196A (zh)	2003-05-14
BG65859B1 (bg)	2010-03-31
UA74571C2 (en)	2006-01-16
SK287163B6 (sk)	2010-02-08
MXPA02008997A (es)	2003-04-25
DE60117131T2 (de)	2006-10-26
EE200200520A (et)	2004-04-15
CN1191241C (zh)	2005-03-02
BG107175A (bg)	2003-05-30
EP1265871B1 (en)	2006-02-08

Similar Documents

Publication	Publication Date	Title
FI105183B (fi)	2000-06-30	Menetelmä sydämen vajaatoiminnan hoidossa käyttökelpoisen (-)-[[4-(1,4,5,6-tetrahydro-4-metyyli-6-okso-3-pyridatsinyyli)-fenyyli]hydratsono]propaanidinitriilin valmistamiseksi
US6121266A (en)	2000-09-19	Pyridazines as interleukin-1β converting enzyme inhibitors
US20090306078A1 (en)	2009-12-10	Compounds that inhibit hif-1 activity, the method for preparation thereof and the pharmaceutical composition containing them as an effective component
JP7469522B2 (ja)	2024-04-16	ベンゾチアゾール類誘導体及びその使用
HRP20020816A2 (en)	2004-12-31	Pyridazinyl phenyl hydrazones useful against congestive heart failure
JPH0570347A (ja)	1993-03-23	臓器用保護剤
JPH06508375A (ja)	1994-09-22	インダン−１，３−ジオンおよびインダン−１，２，３−トリオンの誘導体、それらの調製方法およびそれらの治療上の使用
RU2156252C2 (ru)	2000-09-20	Триазолопиридазины, способ их получения, фармацевтические композиции на их основе и способ лечения
CN117903126B (zh)	2025-06-20	含炔基噻唑甲酰基的甘氨酰胺类化合物及其制备方法和应用
CN115724857B (zh)	2024-06-21	一种芳杂环类化合物、含其的药物组合物及其应用
Sircar et al.	1987	Cardiotonic agents. 6. Synthesis and inotropic activity of 2, 4-dihydro-5-[4-(1H-imidazol-1-yl) phenyl]-3H-pyrazol-3-ones: ring-contracted analogs of imazodan (CI-914)
US6323238B1 (en)	2001-11-27	Benzopyranyl guanidine derivatives, process for preparation thereof, and pharmaceutical compositions containing them
CN113831323A (zh)	2021-12-24	芳杂环酰胺类化合物及其用途
CN112876419A (zh)	2021-06-01	烯丙胺衍生物及其制备方法和用途
HUP0201738A2 (hu)	2003-02-28	Piridazinszármazékok alkalmazása ischémiás szövetkárosodás kezelésére alkalmas gyógyászati készítmények előállítására
JP3159995B2 (ja)	2001-04-23	トルイジン誘導体及びその製造方法
JP3553158B2 (ja)	2004-08-11	ピリダジノインドール誘導体
EP3115359B1 (en)	2019-11-13	Pyridazin-3(2h)-one derivatives which are selective inhibitors of the isoform b of monoamine oxidase
HK40107460A (en)	2024-10-18	Aromatic heterocyclic compound, pharmaceutical composition containing same, and use thereof
CN104003983B (zh)	2016-08-17	含苯硒基取代的双杂环化合物及其制备与应用
WO2003067979A1 (fr)	2003-08-21	Medicaments destines a etre utilises dans la transplantation d'organes
JPS60197660A (ja)	1985-10-07	ピリダジノン誘導体またはその塩類

Legal Events

Date	Code	Title
2004-12-31	A1OB	Publication of a patent application
2005-06-30	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2011-03-02	ODBC	Application rejected