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HRP20020404B1 - Otopine koje sadrže epinastin - Google Patents

Otopine koje sadrže epinastin

Info

Publication number
HRP20020404B1
HRP20020404B1 HR20020404A HRP20020404A HRP20020404B1 HR P20020404 B1 HRP20020404 B1 HR P20020404B1 HR 20020404 A HR20020404 A HR 20020404A HR P20020404 A HRP20020404 A HR P20020404A HR P20020404 B1 HRP20020404 B1 HR P20020404B1
Authority
HR
Croatia
Prior art keywords
optionally
agents
solution
adjusting
epinastine
Prior art date
Application number
HR20020404A
Other languages
English (en)
Inventor
Trach Volker
Duschler Gerold
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7928843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20020404(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of HRP20020404A2 publication Critical patent/HRP20020404A2/hr
Publication of HRP20020404B1 publication Critical patent/HRP20020404B1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F01—MACHINES OR ENGINES IN GENERAL; ENGINE PLANTS IN GENERAL; STEAM ENGINES
    • F01L—CYCLICALLY OPERATING VALVES FOR MACHINES OR ENGINES
    • F01L9/00—Valve-gear or valve arrangements actuated non-mechanically
    • F01L9/20—Valve-gear or valve arrangements actuated non-mechanically by electric means
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Detergent Compositions (AREA)

Abstract

Uporaba otopine, naznačena time, da se sastoji od: a) epinastina kao aktivne supstance, prema potrebi u obliku racemata, enantiomera i prema potrebi u obliku farmakološki prihvatljivih kiselinskih adicijskih soli, u koncentraciji od 0,0005 do 0,1 tež.%, b) vode ili fiziološke otopine soli kao otapala, c) pufera za namještanje pH vrijednosti od 6,5do 7,2, prema potrebi dodavanjem natrij hidroksida, d) konzervansa, te prema potrebie) sredstva za keliranje, f) sredstva za viskozitet, g) sredstva za poboljšanje penetracije, h) antioksidansa, i) i/ili fiziološki prihvatljivih sredstava za namještanje toniciteta otopine, za pripremu lijeka za površinsku primjenu na očnu spojnicu ili nosnu sluznicu za liječenje kasne faze reakcije kod alergijskog rinitisa ili konjuktivitisa. Patent sadrži još 11 patentnih zahtjeva.
HR20020404A 1999-11-12 2000-10-14 Otopine koje sadrže epinastin HRP20020404B1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19954516A DE19954516A1 (de) 1999-11-12 1999-11-12 Epinastin-haltige Lösungen
PCT/EP2000/010122 WO2001035962A1 (de) 1999-11-12 2000-10-14 Epinastin-haltige lösungen

Publications (2)

Publication Number Publication Date
HRP20020404A2 HRP20020404A2 (en) 2004-08-31
HRP20020404B1 true HRP20020404B1 (hr) 2007-08-31

Family

ID=7928843

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20020404A HRP20020404B1 (hr) 1999-11-12 2000-10-14 Otopine koje sadrže epinastin

Country Status (40)

Country Link
US (6) US20030050303A1 (hr)
EP (1) EP1231920B1 (hr)
JP (1) JP2003514021A (hr)
KR (1) KR100758842B1 (hr)
CN (1) CN1292752C (hr)
AR (1) AR026424A1 (hr)
AT (1) ATE353218T1 (hr)
AU (2) AU784017B2 (hr)
BG (1) BG65775B1 (hr)
BR (1) BR0015477A (hr)
CA (1) CA2391076C (hr)
CO (1) CO5251448A1 (hr)
CY (1) CY1106375T1 (hr)
CZ (1) CZ302483B6 (hr)
DE (2) DE19954516A1 (hr)
DK (1) DK1231920T3 (hr)
EA (1) EA006937B1 (hr)
EE (1) EE05395B1 (hr)
ES (1) ES2281359T3 (hr)
HK (1) HK1052303B (hr)
HR (1) HRP20020404B1 (hr)
HU (1) HU229502B1 (hr)
IL (2) IL149501A0 (hr)
ME (1) MEP36708A (hr)
MX (1) MXPA02004556A (hr)
MY (1) MY130441A (hr)
NO (1) NO329417B1 (hr)
NZ (1) NZ519425A (hr)
PE (1) PE20010826A1 (hr)
PL (1) PL198879B1 (hr)
PT (1) PT1231920E (hr)
RS (1) RS50173B (hr)
SA (1) SA01210658B1 (hr)
SI (1) SI1231920T1 (hr)
SK (1) SK287343B6 (hr)
TR (1) TR200201270T2 (hr)
TW (1) TWI225401B (hr)
UA (1) UA74563C2 (hr)
WO (1) WO2001035962A1 (hr)
ZA (1) ZA200203683B (hr)

Families Citing this family (26)

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DE19954516A1 (de) * 1999-11-12 2001-05-17 Boehringer Ingelheim Int Epinastin-haltige Lösungen
EP1531802A1 (en) * 2002-08-02 2005-05-25 Boehringer Ingelheim International GmbH Pharmaceutical formulations comprising combinations of epinastine, pseudoephedrine and methylephedrine
US20040247686A1 (en) * 2003-04-04 2004-12-09 Boehringer Ingelheim International Gmbh Pharmaceutical compositions comprising epinastine for the treatment of skin diseases
EP1468696A1 (en) * 2003-04-17 2004-10-20 Boehringer Ingelheim International GmbH Combinations of epinastine and antiphlogisitcs as new pharmaceutical compositions for the treatment of skin diseases
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
CN101217948A (zh) * 2005-07-08 2008-07-09 千寿制药株式会社 包含依匹那丁的透皮吸收眼科制剂
US20080194544A1 (en) * 2007-02-08 2008-08-14 Ramesh Krishnamoorthy Aqueous formulations of epinastine for treating allergic rhinitis
US7378082B1 (en) 2007-11-05 2008-05-27 Inspire Pharmaceuticals, Inc. Method for treating allergic rhinitis without adverse effects
WO2008098122A2 (en) * 2007-02-08 2008-08-14 Inspire Pharmaceuticals, Inc. Method for treating allergic rhinitis without adverse effects
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ITUB20153950A1 (it) * 2015-09-28 2017-03-28 Tred Srl Dispositivo nasale in grado di attivare il riflesso rino-palatale per l'igienizzazione rinofaringea
JP6134853B1 (ja) * 2016-10-28 2017-05-24 参天製薬株式会社 エピナスチン含有点眼液
JP6635974B2 (ja) * 2017-04-24 2020-01-29 参天製薬株式会社 エピナスチン含有点眼液
KR102582048B1 (ko) * 2017-05-01 2023-09-21 산텐 세이야꾸 가부시키가이샤 점안제
JP2019108320A (ja) * 2018-10-31 2019-07-04 参天製薬株式会社 ソフトコンタクトレンズの変質を抑制する眼科用組成物
JP7599838B2 (ja) * 2019-04-10 2024-12-16 参天製薬株式会社 エピナスチン又はその塩を含有する水性医薬組成物
JP6736752B2 (ja) * 2019-12-17 2020-08-05 参天製薬株式会社 エピナスチン含有点眼液
JP6963651B2 (ja) * 2020-04-16 2021-11-10 参天製薬株式会社 エピナスチン又はその塩を含有する水性組成物
JP7118579B1 (ja) 2020-04-16 2022-08-16 参天製薬株式会社 エピナスチン又はその塩を含有する水性組成物
JP2020169213A (ja) * 2020-07-15 2020-10-15 参天製薬株式会社 エピナスチン含有点眼液
JP7114668B2 (ja) * 2020-10-08 2022-08-08 参天製薬株式会社 エピナスチン又はその塩を含有する花粉破裂抑制剤
CN115448927A (zh) * 2022-10-20 2022-12-09 重庆瑞泊莱医药科技有限公司 一种氢溴酸依匹斯汀晶型ii及其制备方法

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Also Published As

Publication number Publication date
EA200200492A1 (ru) 2002-10-31
PL198879B1 (pl) 2008-07-31
JP2003514021A (ja) 2003-04-15
AU1138101A (en) 2001-05-30
CA2391076C (en) 2008-06-17
PT1231920E (pt) 2007-03-30
AR026424A1 (es) 2003-02-12
HU229502B1 (en) 2014-01-28
ZA200203683B (en) 2003-09-03
SA01210658B1 (ar) 2006-11-05
NO20022201D0 (no) 2002-05-08
TWI225401B (en) 2004-12-21
HUP0203773A3 (en) 2005-01-28
MY130441A (en) 2007-06-29
EE05395B1 (et) 2011-04-15
SK287343B6 (sk) 2010-07-07
TR200201270T2 (tr) 2002-12-23
DK1231920T3 (da) 2007-04-10
ATE353218T1 (de) 2007-02-15
RS50173B (sr) 2009-05-06
CZ302483B6 (cs) 2011-06-08
KR100758842B1 (ko) 2007-09-19
WO2001035962A1 (de) 2001-05-25
AU2006201541A1 (en) 2006-05-11
IL149501A0 (en) 2002-11-10
US20080009476A1 (en) 2008-01-10
EP1231920A1 (de) 2002-08-21
BG65775B1 (bg) 2009-11-30
CN1390129A (zh) 2003-01-08
BG106681A (en) 2002-12-29
EE200200246A (et) 2003-06-16
DE50014041D1 (de) 2007-03-22
CN1292752C (zh) 2007-01-03
UA74563C2 (uk) 2006-01-16
NO20022201L (no) 2002-05-08
CO5251448A1 (es) 2003-02-28
US20070185082A1 (en) 2007-08-09
CZ20021956A3 (cs) 2002-08-14
KR20020050273A (ko) 2002-06-26
BR0015477A (pt) 2002-06-25
HRP20020404A2 (en) 2004-08-31
HUP0203773A2 (hu) 2003-03-28
MEP36708A (en) 2011-02-10
ES2281359T3 (es) 2007-10-01
IL149501A (en) 2012-04-30
US20070197503A1 (en) 2007-08-23
NO329417B1 (no) 2010-10-18
YU33602A (sh) 2005-03-15
HK1052303A1 (en) 2003-09-11
DE19954516A1 (de) 2001-05-17
HK1052303B (zh) 2007-04-13
PE20010826A1 (es) 2001-08-20
PL364028A1 (en) 2004-11-29
US20030050303A1 (en) 2003-03-13
EP1231920B1 (de) 2007-02-07
AU784017B2 (en) 2006-01-12
NZ519425A (en) 2004-04-30
CY1106375T1 (el) 2011-10-12
CA2391076A1 (en) 2001-05-25
EA006937B1 (ru) 2006-06-30
US20090239842A1 (en) 2009-09-24
US7429602B2 (en) 2008-09-30
SK8302002A3 (en) 2002-09-10
MXPA02004556A (es) 2004-09-10
SI1231920T1 (sl) 2007-06-30
US20050288274A1 (en) 2005-12-29

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