HN2009001131A - Derivados de 2,3-dihidroimidazol [1,2-c] quinazolinas sustituidas de utilidad en el tratamiento de trastornos hiperproliferativos y enfermedades asociadas con la angiogenesis - Google Patents
Derivados de 2,3-dihidroimidazol [1,2-c] quinazolinas sustituidas de utilidad en el tratamiento de trastornos hiperproliferativos y enfermedades asociadas con la angiogenesisInfo
- Publication number
- HN2009001131A HN2009001131A HN2009001131A HN2009001131A HN2009001131A HN 2009001131 A HN2009001131 A HN 2009001131A HN 2009001131 A HN2009001131 A HN 2009001131A HN 2009001131 A HN2009001131 A HN 2009001131A HN 2009001131 A HN2009001131 A HN 2009001131A
- Authority
- HN
- Honduras
- Prior art keywords
- treatment
- dihydroimidazol
- angiogenesis
- hyperproliferative disorders
- kinazolines
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 238000011282 treatment Methods 0.000 title abstract 3
- LWTIGYSPAXKMDG-UHFFFAOYSA-N 2,3-dihydro-1h-imidazole Chemical class C1NC=CN1 LWTIGYSPAXKMDG-UHFFFAOYSA-N 0.000 title abstract 2
- 230000033115 angiogenesis Effects 0.000 title abstract 2
- 230000003463 hyperproliferative effect Effects 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000009266 disease activity Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical compound N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 abstract 1
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
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- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
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- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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Abstract
ESTA INVENCION SE REFIERE A NUEVOS COMPUESTOS DE 2,3- DIHIDROIMIDAZOL [1,2-C] QUINAZOLINA, CON COMPOSICIONES FARMACEUTICAS QUE CONTIENEN A DICHOS COMPUESTOS Y CON EL USO DE DICHOS COMPUESTOS O COMPOSICIONES EN LA INHIBICION Y EL TRATAMIENTO DE ENFERMEDADES ASOCIADAS CON LA ACTIVIDAD DE LA FOSFOTIDILINOSITOL-3-QUINASA (P13K), EN PARTICULAR CON EL TRATMIENTO DE TRASTORNOS HIPERPROLIFERATIVOS Y/O DE ANGIOGENESIS, COMO AGENTE UNICO O EN COMBINACIONES CON OTROS INGREDIENTES ACTIVOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87309006P | 2006-12-05 | 2006-12-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HN2009001131A true HN2009001131A (es) | 2012-02-06 |
Family
ID=39492563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HN2009001131A HN2009001131A (es) | 2006-12-05 | 2009-06-04 | Derivados de 2,3-dihidroimidazol [1,2-c] quinazolinas sustituidas de utilidad en el tratamiento de trastornos hiperproliferativos y enfermedades asociadas con la angiogenesis |
Country Status (41)
| Country | Link |
|---|---|
| US (3) | USRE46856E1 (es) |
| EP (1) | EP2096919B1 (es) |
| JP (1) | JP5326092B2 (es) |
| KR (1) | KR101501785B1 (es) |
| CN (4) | CN115724847A (es) |
| AR (1) | AR064106A1 (es) |
| AU (1) | AU2007328008B2 (es) |
| BR (1) | BRPI0720178B8 (es) |
| CA (1) | CA2671614C (es) |
| CL (1) | CL2007003508A1 (es) |
| CO (1) | CO6220908A2 (es) |
| CR (1) | CR10838A (es) |
| CU (1) | CU23796B7 (es) |
| DK (1) | DK2096919T3 (es) |
| DO (1) | DOP2009000135A (es) |
| EA (1) | EA018839B1 (es) |
| EC (1) | ECSP099387A (es) |
| ES (1) | ES2572189T3 (es) |
| GT (1) | GT200900154A (es) |
| HN (1) | HN2009001131A (es) |
| HU (1) | HUE028773T2 (es) |
| IL (1) | IL198273A (es) |
| JO (1) | JO3147B1 (es) |
| MA (1) | MA31283B1 (es) |
| MX (1) | MX2009006001A (es) |
| MY (1) | MY157944A (es) |
| NO (1) | NO342348B1 (es) |
| NZ (1) | NZ577342A (es) |
| PA (1) | PA8759601A1 (es) |
| PE (1) | PE20081444A1 (es) |
| PL (1) | PL2096919T3 (es) |
| RS (1) | RS56045B1 (es) |
| SG (1) | SG177170A1 (es) |
| SI (1) | SI2096919T1 (es) |
| SV (1) | SV2009003288A (es) |
| TN (1) | TN2009000137A1 (es) |
| TW (1) | TWI406662B (es) |
| UA (1) | UA96965C2 (es) |
| UY (1) | UY30761A1 (es) |
| WO (1) | WO2008070150A1 (es) |
| ZA (1) | ZA200904691B (es) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009091550A2 (en) * | 2008-01-14 | 2009-07-23 | Bayer Healthcare Llc | Sulfone substituted 2,3-dihydroimidazo [1,2-c] quinazoline derivatives useful for treating hyper-proliferative disorders and diseases with angiogenesis |
| EP2168583A1 (en) * | 2008-09-24 | 2010-03-31 | Bayer Schering Pharma Aktiengesellschaft | Use of substituted 2,3-dihydroimidazo[1,2-c]quinazolines for the treatment of myeloma |
| EP2168582A1 (en) | 2008-09-24 | 2010-03-31 | Bayer Schering Pharma Aktiengesellschaft | Combinations of substituted 2,3-dihydroimidazo[1,2-c]quinazolines |
| CA2735932C (en) * | 2008-09-30 | 2013-07-09 | Pfizer Inc. | Imidazo[1,5]naphthyridine compounds, their pharmaceutical use and compositions |
| EP2184276A1 (en) | 2008-11-07 | 2010-05-12 | Universite Paul Cezanne Aix-Marseille Iii | Process to prepare new substituted 1H-Benzo(d) imidazol-2(3h)-Ones, New intermediates and their use as bace 1 inhibitors |
| EP2388252B1 (en) | 2009-01-16 | 2013-07-24 | Daiso Co., Ltd. | Process for producing 2-hydroxymethylmorpholine salt |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| CA2796253A1 (en) | 2010-04-16 | 2011-10-20 | Bayer Intellectual Property Gmbh | Substituted 2,3-dihydroimidazo[1,2-c]quinazoline-containing combinations |
| US8933024B2 (en) | 2010-06-18 | 2015-01-13 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| JP2013538215A (ja) | 2010-08-31 | 2013-10-10 | エスエヌユー アールアンドディービー ファウンデーション | PPARδアゴニストの胎児再プログラミング用途 |
| UA113280C2 (xx) * | 2010-11-11 | 2017-01-10 | АМІНОСПИРТЗАМІЩЕНІ ПОХІДНІ 2,3-ДИГІДРОІМІДАЗО$1,2-c]ХІНАЗОЛІНУ, ПРИДАТНІ ДЛЯ ЛІКУВАННЯ ГІПЕРПРОЛІФЕРАТИВНИХ ПОРУШЕНЬ І ЗАХВОРЮВАНЬ, ПОВ'ЯЗАНИХ З АНГІОГЕНЕЗОМ | |
| CA2817287A1 (en) | 2010-11-11 | 2012-05-18 | Bayer Intellectual Property Gmbh | Arylaminoalcohol-substituted 2,3-dihydroimidazo[1,2-c]quinolines |
| CA2817312A1 (en) * | 2010-11-11 | 2012-05-18 | Bayer Intellectual Property Gmbh | Alkoxy-substituted 2,3-dihydroimidazo[1,2-c]quinazolines |
| JO3733B1 (ar) * | 2011-04-05 | 2021-01-31 | Bayer Ip Gmbh | استخدام 3,2-دايهيدروايميدازو[1, 2 -c]كوينازولينات مستبدلة |
| EP2508525A1 (en) * | 2011-04-05 | 2012-10-10 | Bayer Pharma Aktiengesellschaft | Substituted 2,3-dihydroimidazo[1,2-c]quinazoline salts |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
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| WO2014068070A1 (en) | 2012-10-31 | 2014-05-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for preventing antiphospholipid syndrome (aps) |
| DK3150256T3 (da) * | 2012-11-02 | 2020-08-24 | Tg Therapeutics Inc | Kombination af anti-cd20-antistof og pi3-kinaseselektiv hæmmer |
| CN103214489B (zh) * | 2013-02-25 | 2016-10-26 | 中国人民解放军第二军医大学 | 一类具有抗肿瘤活性的多靶点激酶抑制剂及其制备方法 |
| UA119537C2 (uk) * | 2013-04-08 | 2019-07-10 | Байєр Фарма Акцієнгезелльшафт | ЗАСТОСУВАННЯ ЗАМІЩЕНИХ 2,3-ДИГІДРОІМІДАЗО[1,2-c]ХІНАЗОЛІНІВ ДЛЯ ЛІКУВАННЯ ЛІМФОМ |
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