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HK1228925B - 降低脱靶效应的crispr酶突变 - Google Patents

降低脱靶效应的crispr酶突变 Download PDF

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Publication number
HK1228925B
HK1228925B HK17102493.9A HK17102493A HK1228925B HK 1228925 B HK1228925 B HK 1228925B HK 17102493 A HK17102493 A HK 17102493A HK 1228925 B HK1228925 B HK 1228925B
Authority
HK
Hong Kong
Prior art keywords
sequence
crispr
target
cell
protein
Prior art date
Application number
HK17102493.9A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1228925A1 (zh
Inventor
Feng Zhang
Linyi GAO
Bernd ZETSCHE
Ian SLAYMAKER
Original Assignee
Massachusetts Institute Of Technology
The Broad Institute Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute Of Technology, The Broad Institute Inc. filed Critical Massachusetts Institute Of Technology
Publication of HK1228925A1 publication Critical patent/HK1228925A1/zh
Publication of HK1228925B publication Critical patent/HK1228925B/zh

Links

HK17102493.9A 2015-06-18 2016-06-17 降低脱靶效应的crispr酶突变 HK1228925B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US62/181,453 2015-06-18
US62/207,312 2015-08-19
US62/237,360 2015-10-05
US62/255,256 2015-11-13
US62/269,876 2015-12-18

Publications (2)

Publication Number Publication Date
HK1228925A1 HK1228925A1 (zh) 2017-11-10
HK1228925B true HK1228925B (zh) 2022-02-11

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