HK1248588A1 - 用於癌症治疗中的天花疫苗 - Google Patents
用於癌症治疗中的天花疫苗 Download PDFInfo
- Publication number
- HK1248588A1 HK1248588A1 HK18108467.7A HK18108467A HK1248588A1 HK 1248588 A1 HK1248588 A1 HK 1248588A1 HK 18108467 A HK18108467 A HK 18108467A HK 1248588 A1 HK1248588 A1 HK 1248588A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cancer treatment
- smallpox vaccine
- compositions
- disclosed
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
- A61K39/285—Vaccinia virus or variola virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6006—Cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Botany (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562203835P | 2015-08-11 | 2015-08-11 | |
| US201562203835P | 2015-08-11 | ||
| US201562216292P | 2015-09-09 | 2015-09-09 | |
| US201562216292P | 2015-09-09 | ||
| US201662317226P | 2016-04-01 | 2016-04-01 | |
| US201662317226P | 2016-04-01 | ||
| PCT/US2016/046647 WO2017027757A2 (en) | 2015-08-11 | 2016-08-11 | Smallpox vaccine for cancer treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1248588A1 true HK1248588A1 (zh) | 2018-10-19 |
Family
ID=56787706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18108467.7A HK1248588A1 (zh) | 2015-08-11 | 2016-08-11 | 用於癌症治疗中的天花疫苗 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US10105436B2 (zh) |
| EP (1) | EP3334456A2 (zh) |
| JP (1) | JP6788663B2 (zh) |
| KR (1) | KR102201147B1 (zh) |
| CN (2) | CN108135996B (zh) |
| CA (1) | CA3004891C (zh) |
| EA (1) | EA201800148A1 (zh) |
| HK (1) | HK1248588A1 (zh) |
| MX (1) | MX393612B (zh) |
| WO (1) | WO2017027757A2 (zh) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3003133C (en) | 2014-10-24 | 2020-09-15 | StemImmune, Incorporated | Combination immunotherapy approach for treatment of cancer |
| EP3334456A2 (en) | 2015-08-11 | 2018-06-20 | Stemimmune, Incorporated | Smallpox vaccine for use in cancer treatment |
| SG11201903893PA (en) | 2016-11-02 | 2019-05-30 | David Evans | Synthetic chimeric poxviruses |
| KR102776166B1 (ko) | 2017-08-07 | 2025-03-04 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 안전한 세포 치료제를 생성하기 위한 플랫폼 |
| CA3083158A1 (en) | 2017-11-24 | 2019-05-31 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Methods and compositions for treating cancers |
| AR115069A1 (es) | 2018-05-02 | 2020-11-25 | David Evans | Virus vacuna quimérico sintético |
| EP3787681A4 (en) * | 2018-05-02 | 2022-01-19 | Tonix Pharma Holdings Limited | Stem cells comprising synthetic chimeric vaccinia virus and methods of using them |
| US11505782B2 (en) | 2018-06-04 | 2022-11-22 | Calidi Biotherapeutics, Inc. | Cell-based vehicles for potentiation of viral therapy |
| CA3116192C (en) * | 2018-11-06 | 2025-09-23 | Calidi Biotherapeutics (Nevada), Inc. | IMPROVED SYSTEMS FOR CELL-MEDIATED ONCOLYTIC VIRAL THERAPY |
| US20220228128A1 (en) * | 2019-05-30 | 2022-07-21 | Immunolux International Corp. | Use of poxvirus with autologous induced pluripotent stem cells for vaccination and disease therapy |
| WO2020247385A1 (en) * | 2019-06-03 | 2020-12-10 | Immunolux International Corp. | Smallpox vaccine and stem cells for treatment of disease |
| US11110165B2 (en) | 2019-10-10 | 2021-09-07 | Ricardo Rosales Ledezma | Therapeutic vaccine for the treatment of papillomavirus lesions |
| CN116056716B (zh) * | 2020-05-15 | 2025-10-31 | 首尔大学校产学协力团 | 利用从脂肪组织分离出来的基质血管组分的树突状细胞的激活功能的免疫反应增强用组合物 |
| CN116635060A (zh) * | 2020-10-23 | 2023-08-22 | Sk生物科学株式会社 | 包含编码外来抗原的遗传物质的用于减小靶组织的尺寸或体积的疫苗组合物或药盒 |
| KR102766523B1 (ko) * | 2022-04-22 | 2025-02-13 | 에스케이바이오사이언스(주) | 타겟 조직의 크기 또는 부피 축소용 조성물 또는 이를 포함하는 키트 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020010144A1 (en) | 1994-04-29 | 2002-01-24 | Robert Sobol | Enhancing the sensitivity of tumor cells to therapies |
| JP2003514024A (ja) | 1999-11-12 | 2003-04-15 | オンコリティクス バイオテク,インコーポレーテッド | 細胞増殖性疾患の治療のためのウイルス |
| SG179291A1 (en) * | 2003-06-18 | 2012-04-27 | Genelux Corp | Modified recombinant vaccinia viruses and other microorganisms, uses thereof |
| AU2005303912B2 (en) | 2004-11-12 | 2011-02-17 | Bayer Schering Pharma Aktiengesellschaft | Recombinant Newcastle Disease Virus |
| RU2009101783A (ru) | 2006-06-21 | 2010-07-27 | Апогеникс Гмбх (De) | Дифференциальная экспрессия цитокинов il-4 и/или il-10 в злокачественной опухоли человека |
| WO2008009115A1 (en) | 2006-07-18 | 2008-01-24 | Ottawa Health Research Institute | Disparate suicide carrier cells for tumor targeting of promiscuous oncolytic viruses |
| US8052968B2 (en) | 2006-10-16 | 2011-11-08 | Genelux Corporation | Modified vaccinia virus strains for use in diagnostic and therapeutic methods |
| US20100183542A1 (en) | 2006-10-24 | 2010-07-22 | University Of South Alabama | Synergism Between Activated Immune Cells and Conventional Cancer Therapies |
| US8445275B2 (en) | 2007-04-27 | 2013-05-21 | Bavarian Nordic A/S | Induction of dendritic cell development with macrophage-colony stimulating factor (M-CSF) |
| EP2173368A1 (en) | 2007-07-18 | 2010-04-14 | Genelux Corporation | Use of a chemotherapeutic agent in the preparation of a medicament for treating or ameliorating an adverse side effect associated with oncolytic viral therapy |
| WO2009139921A2 (en) * | 2008-05-16 | 2009-11-19 | Genelux Corporation | Microorganisms for preventing and treating neoplasms accompanying cellular therapy |
| PL2350129T3 (pl) | 2008-08-25 | 2015-12-31 | Amplimmune Inc | Kompozycje antagonistów PD-1 i sposoby stosowania |
| EP2352526A1 (en) | 2008-09-19 | 2011-08-10 | Protox Therapeutics Inc. | Treating cancer stem cells using targeted cargo proteins |
| US8691502B2 (en) | 2008-10-31 | 2014-04-08 | Tremrx, Inc. | T-cell vaccination with viral vectors via mechanical epidermal disruption |
| CA2758120C (en) | 2009-04-13 | 2014-08-19 | Apceth Gmbh & Co. Kg | Engineered mesenchymal stem cells and method of using same to treat tumors |
| US20100297072A1 (en) | 2009-05-19 | 2010-11-25 | Depinho Ronald A | Combinations of Immunostimulatory Agents, Oncolytic Virus, and Additional Anticancer Therapy |
| US20110027239A1 (en) | 2009-07-29 | 2011-02-03 | Tissue Genesis, Inc. | Adipose-derived stromal cells (asc) as delivery tool for treatment of cancer |
| WO2011070974A1 (ja) | 2009-12-07 | 2011-06-16 | 国立大学法人名古屋大学 | 脂肪組織由来間葉系幹細胞を含有する、前立腺癌治療用細胞製剤 |
| WO2012051210A2 (en) | 2010-10-11 | 2012-04-19 | The Administrators Of The Tulane Educational Fund | Mesenchymal stem cells and related therapies |
| CN103491978A (zh) | 2010-10-25 | 2014-01-01 | 明尼苏达大学评议会 | 用于治疗成胶质细胞瘤的治疗组合物 |
| EP2764119A2 (en) * | 2011-10-05 | 2014-08-13 | Genelux Corporation | Method for detecting replication or colonization of a biological therapeutic |
| US10238698B2 (en) | 2012-01-25 | 2019-03-26 | Dnatrix, Inc. | Biomarkers and combination therapies using oncolytic virus and immunomodulation |
| KR20170039774A (ko) | 2012-07-30 | 2017-04-11 | 알렉스 와 힌 영 | 종양 세포, 암세포파괴 바이러스 벡터 및 면역 체크포인트 조절인자를 갖는 암 백신 시스템 |
| WO2014066834A1 (en) | 2012-10-26 | 2014-05-01 | The University Of Chicago | Synergistic combination of immunologic inhibitors for the treatment of cancer |
| WO2014160475A1 (en) | 2013-03-13 | 2014-10-02 | Aboody Karen S | Tropic cell based virotherapy for the treatment of cancer |
| CA2905272A1 (en) | 2013-03-14 | 2014-10-02 | Icahn School Of Medicine At Mount Sinai | Newcastle disease viruses and uses thereof |
| US10350275B2 (en) | 2013-09-21 | 2019-07-16 | Advantagene, Inc. | Methods of cytotoxic gene therapy to treat tumors |
| WO2015089280A1 (en) | 2013-12-11 | 2015-06-18 | The General Hospital Corporation | Stem cell delivered oncolytic herpes simplex virus and methods for treating brain tumors |
| PT3169341T (pt) | 2014-07-16 | 2019-09-09 | Transgene Sa | Vírus oncolítico para a expressão de moduladores de pontos de controlo imunitário |
| CA3003133C (en) | 2014-10-24 | 2020-09-15 | StemImmune, Incorporated | Combination immunotherapy approach for treatment of cancer |
| AU2016232863A1 (en) | 2015-03-18 | 2017-11-09 | StemImmune, Incorporated | Virotherapy with an antibody combination |
| EP3334456A2 (en) | 2015-08-11 | 2018-06-20 | Stemimmune, Incorporated | Smallpox vaccine for use in cancer treatment |
| US11505782B2 (en) | 2018-06-04 | 2022-11-22 | Calidi Biotherapeutics, Inc. | Cell-based vehicles for potentiation of viral therapy |
| KR20240060879A (ko) | 2018-06-04 | 2024-05-08 | 카리디 바이오테라퓨틱스, 인크. | 바이러스 치료법의 강화를 위한 세포-기반 비히클 |
| CA3116192C (en) | 2018-11-06 | 2025-09-23 | Calidi Biotherapeutics (Nevada), Inc. | IMPROVED SYSTEMS FOR CELL-MEDIATED ONCOLYTIC VIRAL THERAPY |
| WO2020247385A1 (en) | 2019-06-03 | 2020-12-10 | Immunolux International Corp. | Smallpox vaccine and stem cells for treatment of disease |
-
2016
- 2016-08-11 EP EP16754618.3A patent/EP3334456A2/en active Pending
- 2016-08-11 CN CN201680058874.XA patent/CN108135996B/zh active Active
- 2016-08-11 MX MX2018001755A patent/MX393612B/es unknown
- 2016-08-11 KR KR1020187007019A patent/KR102201147B1/ko active Active
- 2016-08-11 JP JP2018507579A patent/JP6788663B2/ja active Active
- 2016-08-11 HK HK18108467.7A patent/HK1248588A1/zh unknown
- 2016-08-11 US US15/235,082 patent/US10105436B2/en active Active
- 2016-08-11 EA EA201800148A patent/EA201800148A1/ru unknown
- 2016-08-11 CN CN202210672164.3A patent/CN115212301A/zh active Pending
- 2016-08-11 CA CA3004891A patent/CA3004891C/en active Active
- 2016-08-11 WO PCT/US2016/046647 patent/WO2017027757A2/en not_active Ceased
-
2018
- 2018-07-24 US US16/044,136 patent/US10857225B2/en active Active
-
2020
- 2020-11-04 US US17/089,527 patent/US11607450B2/en active Active
-
2023
- 2023-01-30 US US18/103,214 patent/US12036278B2/en active Active
-
2024
- 2024-06-14 US US18/743,581 patent/US20240335530A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20210046178A1 (en) | 2021-02-18 |
| US20230173062A1 (en) | 2023-06-08 |
| CA3004891A1 (en) | 2017-02-16 |
| CN108135996B (zh) | 2022-06-21 |
| KR102201147B1 (ko) | 2021-01-11 |
| WO2017027757A2 (en) | 2017-02-16 |
| CN115212301A (zh) | 2022-10-21 |
| EP3334456A2 (en) | 2018-06-20 |
| US10105436B2 (en) | 2018-10-23 |
| EA201800148A1 (ru) | 2019-01-31 |
| MX2018001755A (es) | 2018-08-01 |
| JP6788663B2 (ja) | 2020-11-25 |
| JP2018527344A (ja) | 2018-09-20 |
| US12036278B2 (en) | 2024-07-16 |
| CN108135996A (zh) | 2018-06-08 |
| KR20180042284A (ko) | 2018-04-25 |
| US10857225B2 (en) | 2020-12-08 |
| US20240335530A1 (en) | 2024-10-10 |
| US20180326048A1 (en) | 2018-11-15 |
| CA3004891C (en) | 2020-04-14 |
| MX393612B (es) | 2025-03-24 |
| US20170043010A1 (en) | 2017-02-16 |
| US11607450B2 (en) | 2023-03-21 |
| WO2017027757A3 (en) | 2017-03-23 |
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Legal Events
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| CHRG | Changes in the register |