MX2017002489A - Agentes terapeuticos humanos. - Google Patents
Agentes terapeuticos humanos.Info
- Publication number
- MX2017002489A MX2017002489A MX2017002489A MX2017002489A MX2017002489A MX 2017002489 A MX2017002489 A MX 2017002489A MX 2017002489 A MX2017002489 A MX 2017002489A MX 2017002489 A MX2017002489 A MX 2017002489A MX 2017002489 A MX2017002489 A MX 2017002489A
- Authority
- MX
- Mexico
- Prior art keywords
- therapeutic agents
- human therapeutic
- human
- component
- agents
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- BXNJHAXVSOCGBA-UHFFFAOYSA-N Harmine Chemical compound N1=CC=C2C3=CC=C(OC)C=C3NC2=C1C BXNJHAXVSOCGBA-UHFFFAOYSA-N 0.000 abstract 2
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 abstract 2
- JVTZFYYHCGSXJV-UHFFFAOYSA-N isovanillin Chemical compound COC1=CC=C(C=O)C=C1O JVTZFYYHCGSXJV-UHFFFAOYSA-N 0.000 abstract 2
- RERZNCLIYCABFS-UHFFFAOYSA-N Harmaline hydrochloride Natural products C1CN=C(C)C2=C1C1=CC=C(OC)C=C1N2 RERZNCLIYCABFS-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229940109262 curcumin Drugs 0.000 abstract 1
- 235000012754 curcumin Nutrition 0.000 abstract 1
- 239000004148 curcumin Substances 0.000 abstract 1
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 abstract 1
- VJHLDRVYTQNASM-UHFFFAOYSA-N harmine Natural products CC1=CN=CC=2NC3=CC(=CC=C3C=21)OC VJHLDRVYTQNASM-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se relaciona con composiciones de tratamiento terapéuticas humanas que comprenden por lo menos dos de un componente de curcumina, un componente de harmina y un componente de isovainillina, y de preferencia, los tres en combinación. Los agentes son efectivos para el tratamiento de afecciones humanas, especialmente cánceres humanos.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462066686P | 2014-10-21 | 2014-10-21 | |
| US201562161090P | 2015-05-13 | 2015-05-13 | |
| US14/721,011 US9402834B2 (en) | 2014-10-21 | 2015-05-26 | Human therapeutic agents |
| US201562184051P | 2015-06-24 | 2015-06-24 | |
| PCT/US2015/055968 WO2016064676A1 (en) | 2014-10-21 | 2015-10-16 | Human therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2017002489A true MX2017002489A (es) | 2017-09-13 |
Family
ID=55761352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017002489A MX2017002489A (es) | 2014-10-21 | 2015-10-16 | Agentes terapeuticos humanos. |
Country Status (13)
| Country | Link |
|---|---|
| EP (2) | EP3188721B1 (es) |
| JP (1) | JP6937237B2 (es) |
| KR (1) | KR20170066425A (es) |
| CN (3) | CN115569136A (es) |
| AU (1) | AU2015336311B2 (es) |
| CA (1) | CA2955114C (es) |
| DK (1) | DK3188721T3 (es) |
| ES (1) | ES2744913T3 (es) |
| IL (1) | IL250990A0 (es) |
| MX (1) | MX2017002489A (es) |
| RU (1) | RU2017115885A (es) |
| TW (1) | TW201625230A (es) |
| WO (1) | WO2016064676A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016181220A2 (en) * | 2015-05-13 | 2016-11-17 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions and methods of use thereof |
| CA3086925A1 (en) | 2018-01-05 | 2019-07-11 | Ichan School Of Medicine At Mount Sinai | Method of increasing proliferation of pancreatic beta cells, treatment method, and composition |
| US11246902B2 (en) * | 2018-02-23 | 2022-02-15 | Ankh Life Sciences Limited | Nutritional supplement for mammals |
| CN112135613A (zh) | 2018-03-20 | 2020-12-25 | 西奈山伊坎医学院 | 激酶抑制剂化合物和组合物及使用方法 |
| US11452715B2 (en) | 2018-04-13 | 2022-09-27 | Ankh Life Sciences Limited | Thymoquinone/harmaline and related reaction products |
| US11453664B2 (en) | 2018-04-13 | 2022-09-27 | Ankh Life Sciences Limited | Thymoquinone/harmaline and related reaction products |
| US11453665B2 (en) | 2018-04-13 | 2022-09-27 | Ankh Life Sciences Limited | Thymoquinone/harmaline and related reaction products |
| US10875859B2 (en) | 2018-04-13 | 2020-12-29 | Ankh Life Sciences Limited | Thymoquinone/harmaline and related reaction products |
| US10947253B2 (en) | 2019-08-05 | 2021-03-16 | Ankh Life Sciences Limited | Fused polycyclic dimers |
| US12419872B2 (en) | 2020-03-05 | 2025-09-23 | Ankh Life Sciences Limited | Low-temperature synthesis of thymoquinone and harmaline compounds |
| WO2022019892A1 (en) * | 2020-07-21 | 2022-01-27 | Ankh Life Sciences Limited | Therapeutic agents and uses thereof |
| US12129265B2 (en) | 2020-07-21 | 2024-10-29 | Ankh Life Sciences Limited | Therapeutic agents and uses thereof |
| JP2023080697A (ja) * | 2021-11-30 | 2023-06-09 | 株式会社渡辺オイスター研究所 | 転移性ヒト前立腺がん細胞の増殖抑制剤 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54126731A (en) * | 1978-03-20 | 1979-10-02 | Rikagaku Kenkyusho | Carcinostatic agent |
| US7355081B2 (en) * | 2002-04-17 | 2008-04-08 | The University Of North Carolina At Chapel Hill | Curcumin analogues and uses thereof |
| JP2004075666A (ja) * | 2002-05-15 | 2004-03-11 | Keio Gijuku | 造血器腫瘍の治療薬、免疫抑制剤、およびp53を標的分子とする分子標的治療薬 |
| CN100503607C (zh) * | 2003-06-02 | 2009-06-24 | 新疆华世丹药物研究有限责任公司 | 去氢骆驼蓬碱衍生物类化合物及其应用 |
| FR2869540B1 (fr) * | 2004-04-30 | 2008-05-16 | Centre Nat Rech Scient Cnrse | Compositions pharmaceutiques contenant des derives de b-carboline, et leur utilisation pour le traitement des cancers |
| CN100553628C (zh) * | 2005-08-25 | 2009-10-28 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 2-溴-异香兰素在制备抗癌和/或辐射、化疗增敏药物中的应用 |
| US8735154B2 (en) | 2006-10-30 | 2014-05-27 | The University Of Kansas | Templated islet cells and small islet cell clusters for diabetes treatment |
| WO2008150899A1 (en) * | 2007-05-29 | 2008-12-11 | Emory University | Combination therapies for treatment of cancer and inflammatory diseases |
| CN101669931B (zh) * | 2008-09-08 | 2012-07-04 | 北京鼎国昌盛生物技术有限责任公司 | 长效姜黄素衍生物在制备抗肿瘤症药物中的应用 |
| EP2418943A4 (en) * | 2009-04-15 | 2012-08-29 | Univ Ohio State Res Found | CURCUMIN ANALOGUES AS DOUBLE JAK2 / STAT3 INHIBITORS AND METHODS FOR THE PREPARATION AND USE THEREOF |
| WO2011133795A2 (en) * | 2010-04-22 | 2011-10-27 | The Brigham And Women's Hospital, Inc. | Beta-carbolines as inhibitors of haspin and dyrk kinases |
| US20120058208A1 (en) * | 2010-09-04 | 2012-03-08 | Synthite Industries Ltd. | Synergistic Composition for Enhancing Bioavailability of Curcumin |
| WO2012047852A2 (en) * | 2010-10-07 | 2012-04-12 | The J. David Gladstone Institutes | Compositions and methods for modulating immunodeficiency virus transcription |
| US8039025B1 (en) | 2010-10-15 | 2011-10-18 | Life Plus, LLC | Methods and dosage forms for the treatment of human cancers |
| WO2015006646A1 (en) * | 2013-07-11 | 2015-01-15 | Specialty Nutrition Group, Inc. | Compositions comprising hydroxytyrosol, curcumin, and/or astaxanthin and use thereof |
-
2015
- 2015-10-16 CN CN202210871857.5A patent/CN115569136A/zh active Pending
- 2015-10-16 ES ES15853030T patent/ES2744913T3/es active Active
- 2015-10-16 KR KR1020177009791A patent/KR20170066425A/ko not_active Withdrawn
- 2015-10-16 AU AU2015336311A patent/AU2015336311B2/en active Active
- 2015-10-16 DK DK15853030.3T patent/DK3188721T3/da active
- 2015-10-16 MX MX2017002489A patent/MX2017002489A/es unknown
- 2015-10-16 WO PCT/US2015/055968 patent/WO2016064676A1/en not_active Ceased
- 2015-10-16 RU RU2017115885A patent/RU2017115885A/ru not_active Application Discontinuation
- 2015-10-16 JP JP2017522542A patent/JP6937237B2/ja active Active
- 2015-10-16 CN CN201911016462.1A patent/CN110772512A/zh active Pending
- 2015-10-16 EP EP15853030.3A patent/EP3188721B1/en active Active
- 2015-10-16 CN CN201580057827.9A patent/CN107106519B/zh active Active
- 2015-10-16 CA CA2955114A patent/CA2955114C/en active Active
- 2015-10-16 EP EP17185821.0A patent/EP3275465B1/en active Active
- 2015-10-21 TW TW104134465A patent/TW201625230A/zh unknown
-
2017
- 2017-03-07 IL IL250990A patent/IL250990A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN107106519A (zh) | 2017-08-29 |
| IL250990A0 (en) | 2017-04-30 |
| TW201625230A (zh) | 2016-07-16 |
| CA2955114C (en) | 2023-01-03 |
| AU2015336311A1 (en) | 2017-02-09 |
| CN107106519B (zh) | 2023-01-24 |
| WO2016064676A1 (en) | 2016-04-28 |
| ES2744913T3 (es) | 2020-02-26 |
| JP2017531689A (ja) | 2017-10-26 |
| DK3188721T3 (da) | 2019-08-12 |
| CN115569136A (zh) | 2023-01-06 |
| AU2015336311B2 (en) | 2020-05-14 |
| CN110772512A (zh) | 2020-02-11 |
| AU2015336311A2 (en) | 2020-02-06 |
| EP3188721A1 (en) | 2017-07-12 |
| JP6937237B2 (ja) | 2021-09-22 |
| EP3188721B1 (en) | 2019-06-12 |
| KR20170066425A (ko) | 2017-06-14 |
| BR112017006190A2 (pt) | 2017-12-26 |
| RU2017115885A (ru) | 2018-11-23 |
| EP3275465A1 (en) | 2018-01-31 |
| EP3188721A4 (en) | 2018-05-02 |
| EP3275465B1 (en) | 2020-05-06 |
| CA2955114A1 (en) | 2016-04-28 |
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