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HK1098071B - 能夠與配位體的共軛單甲基纈氨酸化合物 - Google Patents

能夠與配位體的共軛單甲基纈氨酸化合物 Download PDF

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Publication number
HK1098071B
HK1098071B HK07105547.0A HK07105547A HK1098071B HK 1098071 B HK1098071 B HK 1098071B HK 07105547 A HK07105547 A HK 07105547A HK 1098071 B HK1098071 B HK 1098071B
Authority
HK
Hong Kong
Prior art keywords
antibody
alkyl
pharmaceutically acceptable
solvate
acceptable salt
Prior art date
Application number
HK07105547.0A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1098071A1 (zh
Inventor
O. Doronina Svetlana
D. Senter Peter
E. Toki Brian
J. Ebens Allen
Beth Kline Toni
Polakis Paul
X. Sliwkowski Mark
D. Spencer Susan
Original Assignee
Seattle Genetics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seattle Genetics, Inc. filed Critical Seattle Genetics, Inc.
Priority claimed from PCT/US2004/038392 external-priority patent/WO2005081711A2/en
Publication of HK1098071A1 publication Critical patent/HK1098071A1/zh
Publication of HK1098071B publication Critical patent/HK1098071B/zh

Links

HK07105547.0A 2003-11-06 2004-11-05 能夠與配位體的共軛單甲基纈氨酸化合物 HK1098071B (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US51853403P 2003-11-06 2003-11-06
US60/518,534 2003-11-06
US55711604P 2004-03-26 2004-03-26
US60/557,116 2004-03-26
US59889904P 2004-08-04 2004-08-04
US60/598,899 2004-08-04
US62245504P 2004-10-27 2004-10-27
US60/622,455 2004-10-27
PCT/US2004/038392 WO2005081711A2 (en) 2003-11-06 2004-11-05 Monomethylvaline compounds capable of conjugation to ligands

Related Parent Applications (3)

Application Number Title Priority Date Filing Date
HK13101170.5A Division HK1173682B (zh) 2003-11-06 2007-05-28 單甲基纈氨酸化合物與抗體結合
HK13101177.8A Division HK1173684B (zh) 2003-11-06 2007-05-28 單甲基纈氨酸化合物結合到抗體上
HK13100725.7A Division HK1173382B (zh) 2003-11-06 2007-05-28 具抗-her2或抗-cd22抗體的auristatin共軛及其治療用途

Related Child Applications (3)

Application Number Title Priority Date Filing Date
HK13101170.5A Addition HK1173682B (zh) 2003-11-06 2007-05-28 單甲基纈氨酸化合物與抗體結合
HK13101177.8A Addition HK1173684B (zh) 2003-11-06 2007-05-28 單甲基纈氨酸化合物結合到抗體上
HK13100725.7A Addition HK1173382B (zh) 2003-11-06 2007-05-28 具抗-her2或抗-cd22抗體的auristatin共軛及其治療用途

Publications (2)

Publication Number Publication Date
HK1098071A1 HK1098071A1 (zh) 2007-07-13
HK1098071B true HK1098071B (zh) 2014-06-06

Family

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