HK1040921B - 含有多孔粒子形态的药物 - Google Patents

含有多孔粒子形态的药物 Download PDF

Info

Publication number: HK1040921B
Authority: HK; Hong Kong
Prior art keywords: dosage form; active agent; particles; liquid; drug
Prior art date: 1998-12-23

Application number

HK02102704.1A

Other languages

German (de)

English (en)

French (fr)

Other versions

HK1040921A1 (zh

Inventor

Wong Patrick

Edgren David

Dong Liang-Chang

Pollock-Dove Crystal

Original Assignee

Alza Corporation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-23

Filing date

1999-12-23

Publication date

2005-12-30

1999-12-23 Application filed by Alza Corporation filed Critical Alza Corporation

2002-06-28 Publication of HK1040921A1 publication Critical patent/HK1040921A1/zh

2005-12-30 Publication of HK1040921B publication Critical patent/HK1040921B/zh

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/501—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Inorganic Chemistry (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Endocrinology (AREA)
Obesity (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)
Child & Adolescent Psychology (AREA)
Rheumatology (AREA)
Psychiatry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Transplantation (AREA)
Gynecology & Obstetrics (AREA)
Reproductive Health (AREA)
Emergency Medicine (AREA)
Virology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Nutrition Science (AREA)
Physiology (AREA)

HK02102704.1A 1998-12-23 1999-12-23 含有多孔粒子形态的药物 HK1040921B (zh)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
US11361598P	1998-12-23	1998-12-23
US11355998P	1998-12-23	1998-12-23
US11375098P	1998-12-23	1998-12-23
US60/113,559		1998-12-23
US60/113,615		1998-12-23
US60/113,750		1998-12-23
PCT/GB1999/004426 WO2000038655A1 (en)	1998-12-23	1999-12-23	Dosage forms comprising porous particles

Publications (2)

Publication Number	Publication Date
HK1040921A1 HK1040921A1 (zh)	2002-06-28
HK1040921B true HK1040921B (zh)	2005-12-30

Family

ID=27381339

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK02102704.1A HK1040921B (zh)	1998-12-23	1999-12-23	含有多孔粒子形态的药物

Country Status (12)

Country	Link
EP (1)	EP1140027B1 (zh)
JP (1)	JP2002533380A (zh)
KR (1)	KR100618234B1 (zh)
AT (1)	ATE306250T1 (zh)
AU (1)	AU1881600A (zh)
CA (1)	CA2355860C (zh)
DE (1)	DE69927708T2 (zh)
DK (1)	DK1140027T3 (zh)
ES (1)	ES2251251T3 (zh)
HK (1)	HK1040921B (zh)
IL (2)	IL143846A0 (zh)
WO (1)	WO2000038655A1 (zh)

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GB9808052D0 (en)	1998-04-17	1998-06-17	Secr Defence	Implants for administering substances and methods of producing implants
US6793934B1 (en) *	1999-12-08	2004-09-21	Shire Laboratories, Inc.	Solid oral dosage form
WO2002028181A1 (en) *	2000-10-02	2002-04-11	Usv Limited	Sustained release pharmaceutical compositions containing metformin and method of its production
AU2002317466B2 (en)	2001-07-12	2008-02-28	Given Imaging Ltd	Device and method for examining a body lumen
KR20050043765A (ko) *	2001-11-06	2005-05-11	랜박시 래보러터리스 리미티드	방출 제어형 메트포르민 정제
CA2471096A1 (en) *	2001-12-19	2003-07-03	Alza Corporation	Formulation and dosage form for increasing oral bioavailability of hydrophilic macromolecules
SE0200895D0 (sv) *	2002-03-22	2002-03-22	Astrazeneca Ab	New pharmaceutical composition
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IL166023A0 (en) *	2002-06-28	2006-01-15	Alza Corp	Oral dosage from comprising a liquid active agent formulation and controlling release thereof by an expandable osmotic composition
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EP1771243A1 (en) *	2004-06-28	2007-04-11	H.Lundbeck A/S	Porous article for delivering chemical substances
FR2873923B1 (fr) *	2004-08-05	2007-01-12	Gattefosse Holding Sa	Particule solide anhydre contenant une composition lipidique liquide et composition pharmaceutique contenant lesdites particules
GB0420016D0 (en)	2004-09-09	2004-10-13	Leuven K U Res & Dev	Controlled release oral delivery system
WO2006056042A1 (en) *	2004-11-03	2006-06-01	Equitech Corporation	Nsaid compositions exhibiting clinical superiority
WO2006132307A1 (ja)	2005-06-10	2006-12-14	Pierre Fabre Medicament S.A.	安定化されたミルナシプラン製剤
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KR100669497B1 (ko) *	2005-08-17	2007-01-16	보람제약주식회사	안정성과 용출률이 뛰어난 약리학적 조성물 및 그 제조방법
KR101164516B1 (ko) *	2005-12-31	2012-07-13	태슬리 파마슈티컬 그룹 컴퍼니 리미티드	양명아주 추출물을 함유하는 약학 조성물, 및 이의 제조방법 및 용도
DK1973529T3 (da) *	2006-01-05	2011-09-12	Veloxis Pharmaceuticals As	Fyldbar tablet, som er i stand til at falde hen
GB0709541D0 (en) *	2007-05-17	2007-06-27	Jagotec Ag	Pharmaceutical excipient
EP2223702B1 (en) *	2007-12-03	2019-05-08	Tomita Pharmaceutical Co., Ltd.	Core particle for pharmaceutical preparation
US9150419B2 (en) *	2008-05-10	2015-10-06	Us Synthetic Corporation	Polycrystalline articles for reagent delivery
EP2135601A1 (en) *	2008-06-20	2009-12-23	Capsulution Nanoscience AG	Stabilization of amorphous drugs using sponge-like carrier matrices
JP5560701B2 (ja) *	2008-12-26	2014-07-30	ライオン株式会社	ラニチジン含有医薬固形製剤及びラニチジン担持粒子の製造方法
CN102413813B (zh) *	2009-03-24	2014-11-12	Adds制药有限责任公司	用于口服递送的稳定化的溶解性增强的制剂
CN105476951A (zh)	2009-05-04	2016-04-13	普西维达公司	多孔硅药物洗脱颗粒
US8798388B2 (en)	2009-12-03	2014-08-05	Qualcomm Incorporated	Digital image combining to produce optical effects
EP2515759A4 (en)	2009-12-23	2015-01-21	Given Imaging Inc	METHOD OF ASSESSING CONSTIPATION USING INGREDIENT CAPSULE
US20110244031A1 (en) *	2010-03-31	2011-10-06	Lifecycle Pharma A/S	Porous tablets as carriers for liquid formulations
AU2011264941B2 (en) *	2010-06-07	2014-10-16	Suda Ltd	Oral spray formulations and methods for administration of sildenafil
JP6026424B2 (ja)	2010-11-01	2016-11-16	シヴィダ・ユーエス・インコーポレイテッドＰｓｉｖｉｄａＵｓ，Ｉｎｃ．	治療薬送達のための生物浸食性ケイ素ベースのデバイス
WO2012166949A1 (en)	2011-05-31	2012-12-06	Regents Of The University Of Minnesota	Silicate prodrugs and nanoparticles
US9186321B2 (en) *	2011-12-05	2015-11-17	Suda Ltd.	Oral spray formulations and methods for administration of sildenafil
PT3677252T (pt)	2012-03-19	2023-10-02	Cidara Therapeutics Inc	Regimes de dosagem para compostos da classe equinocandina
WO2013175303A1 (en)	2012-05-21	2013-11-28	Capsugel Belgium Nv	Acid resistant banding solution for two piece hard capsules
CA2875818A1 (en) *	2012-07-27	2014-01-30	Wellesley Pharmaceuticals, Llc	Pharmaceutical formulation for bedwetting and method of use thereof
US20140309610A1 (en) *	2013-03-12	2014-10-16	Psivida Corp.	Drug Delivery Device Comprising Silicon-Based Carrier Particles
WO2014151381A1 (en)	2013-03-15	2014-09-25	Psivida Us, Inc.	Bioerodible silicon-based compositions for delivery of therapeutic agents
US9962336B2 (en)	2014-05-01	2018-05-08	Sun Pharmaceutical Industries Limited	Extended release suspension compositions
WO2015166472A1 (en) *	2014-05-01	2015-11-05	Sun Pharmaceutical Industries Limited	Extended release liquid compositions of metformin
EP3137060B2 (en)	2014-05-01	2023-12-20	Sun Pharmaceutical Industries Ltd	Extended release suspension compositions
US10258583B2 (en)	2014-05-01	2019-04-16	Sun Pharmaceutical Industries Limited	Extended release liquid compositions of guanfacine
US20180104197A9 (en)	2014-05-01	2018-04-19	Sun Pharmaceutical Industries Limited	Extended release liquid compositions of metformin
CA2956902A1 (en)	2014-07-30	2016-02-04	Sun Pharmaceutical Industries Limited	Dual-chamber pack
MA41124A (fr) *	2014-12-05	2017-10-10	Sun Pharmaceutical Ind Ltd	Compositions en suspension à libération prolongée à rétention gastrique
EP3236946A1 (en) *	2014-12-23	2017-11-01	Lucideon Limited	Porous particles
GB201502073D0 (en)	2015-02-09	2015-03-25	Cubic Pharmaceuticals Ltd And Delta Pharmaceuticals Ltd	HDEG technology
US10238803B2 (en)	2016-05-02	2019-03-26	Sun Pharmaceutical Industries Limited	Drug delivery device for pharmaceutical compositions
US10369078B2 (en)	2016-05-02	2019-08-06	Sun Pharmaceutical Industries Limited	Dual-chamber pack for pharmaceutical compositions
JP2021528452A (ja) *	2018-06-25	2021-10-21	タイタンファーマシューティカルズインコーポレイテッド	インプラントとして使用するための装填可能な多孔質構造
CA3139217A1 (en)	2019-05-14	2020-11-19	Clexio Biosciences Ltd.	Treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease
WO2022195476A1 (en)	2021-03-15	2022-09-22	Clexio Biosciences Ltd.	Gastroretentive devices for assessment of intragastric conditions
CN115924903B (zh) *	2022-12-01	2024-08-20	复旦大学	一种二维单层有序介孔碳框架的制备方法

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GB8413191D0 (en) *	1984-05-23	1984-06-27	Beecham Group Plc	Pharmaceutical composition
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1999
- 1999-12-23 AU AU18816/00A patent/AU1881600A/en not_active Abandoned
- 1999-12-23 DE DE69927708T patent/DE69927708T2/de not_active Expired - Lifetime
- 1999-12-23 AT AT99962459T patent/ATE306250T1/de active
- 1999-12-23 CA CA2355860A patent/CA2355860C/en not_active Expired - Fee Related
- 1999-12-23 DK DK99962459T patent/DK1140027T3/da active
- 1999-12-23 KR KR1020017008072A patent/KR100618234B1/ko not_active Expired - Fee Related
- 1999-12-23 IL IL14384699A patent/IL143846A0/xx active IP Right Grant
- 1999-12-23 EP EP99962459A patent/EP1140027B1/en not_active Expired - Lifetime
- 1999-12-23 JP JP2000590609A patent/JP2002533380A/ja not_active Withdrawn
- 1999-12-23 HK HK02102704.1A patent/HK1040921B/zh not_active IP Right Cessation
- 1999-12-23 ES ES99962459T patent/ES2251251T3/es not_active Expired - Lifetime
- 1999-12-23 WO PCT/GB1999/004426 patent/WO2000038655A1/en not_active Ceased
2001
- 2001-06-19 IL IL143846A patent/IL143846A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL143846A (en)	2007-03-08
AU1881600A (en)	2000-07-31
WO2000038655A1 (en)	2000-07-06
DK1140027T3 (da)	2006-02-27
HK1040921A1 (zh)	2002-06-28
IL143846A0 (en)	2002-04-21
JP2002533380A (ja)	2002-10-08
EP1140027B1 (en)	2005-10-12
EP1140027A1 (en)	2001-10-10
CA2355860C (en)	2010-03-30
KR100618234B1 (ko)	2006-09-01
DE69927708T2 (de)	2006-07-06
DE69927708D1 (de)	2006-02-23
CA2355860A1 (en)	2000-07-06
KR20010093218A (ko)	2001-10-27
ATE306250T1 (de)	2005-10-15
ES2251251T3 (es)	2006-04-16

Publication	Publication Date	Title
EP1140027B1 (en)	2005-10-12	Dosage forms comprising porous particles
US6635281B2 (en)	2003-10-21	Gastric retaining oral liquid dosage form
US6797283B1 (en)	2004-09-28	Gastric retention dosage form having multiple layers
US6342249B1 (en)	2002-01-29	Controlled release liquid active agent formulation dosage forms
US6120803A (en)	2000-09-19	Prolonged release active agent dosage form adapted for gastric retention
EP2238975B1 (en)	2012-12-05	Gastric retention controlled drug delivery system
US20060057206A1 (en)	2006-03-16	Controlled release nanoparticle active agent formulation dosage forms and methods
JP2007516297A (ja)	2007-06-21	制御送達用薬剤組成物の溶解度を高くする方法および投薬形態物
JP2002528486A (ja)	2002-09-03	有効物質の送達制御
CZ189597A3 (cs)	1998-02-18	Dávkovací prostředek pro řízené uvolňování suspenze léčiva
AU710389B2 (en)	1999-09-16	Uniform drug delivery therapy
WO2000038650A1 (en)	2000-07-06	Gastric retention dosage form having multiple layers
US20030203029A1 (en)	2003-10-30	Controlled release liquid active agent formulation dosage forms
US20050048120A1 (en)	2005-03-03	Dosage form comprising self-destructive membrane
CA2586473C (en)	2011-05-31	Uniform drug delivery therapy
HK1028196B (zh)	2005-07-15	适用於留在胃中的延长释放的活性剂剂型
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