[go: up one dir, main page]

GR20010300003T1 - Regulation of quinolate phosphoribosyl transferase expression - Google Patents

Regulation of quinolate phosphoribosyl transferase expression

Info

Publication number
GR20010300003T1
GR20010300003T1 GR20010300003T GR20010300003T GR20010300003T1 GR 20010300003 T1 GR20010300003 T1 GR 20010300003T1 GR 20010300003 T GR20010300003 T GR 20010300003T GR 20010300003 T GR20010300003 T GR 20010300003T GR 20010300003 T1 GR20010300003 T1 GR 20010300003T1
Authority
GR
Greece
Prior art keywords
regulation
phosphoribosyl transferase
quinolate phosphoribosyl
transferase expression
expression
Prior art date
Application number
GR20010300003T
Other languages
English (en)
Inventor
Mark A Conkling
Nandini Mendu
Wen Song
Original Assignee
Univ North Carolina State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21960004&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR20010300003(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ North Carolina State filed Critical Univ North Carolina State
Publication of GR20010300003T1 publication Critical patent/GR20010300003T1/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1077Pentosyltransferases (2.4.2)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Physiology (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Manufacture Of Tobacco Products (AREA)
GR20010300003T 1997-06-12 2001-06-29 Regulation of quinolate phosphoribosyl transferase expression GR20010300003T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4947197P 1997-06-12 1997-06-12
PCT/US1998/011893 WO1998056923A1 (en) 1997-06-12 1998-06-10 Regulation of quinolate phosphoribosyl transferase expression

Publications (1)

Publication Number Publication Date
GR20010300003T1 true GR20010300003T1 (en) 2001-06-29

Family

ID=21960004

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010300003T GR20010300003T1 (en) 1997-06-12 2001-06-29 Regulation of quinolate phosphoribosyl transferase expression

Country Status (37)

Country Link
US (9) US6586661B1 (el)
EP (3) EP0991766B1 (el)
JP (4) JP4095678B2 (el)
KR (1) KR100365969B1 (el)
CN (2) CN100482799C (el)
AP (1) AP1169A (el)
AT (1) ATE262039T1 (el)
AU (1) AU748514B2 (el)
BG (1) BG64319B1 (el)
BR (1) BRPI9810870B1 (el)
CA (2) CA2287776C (el)
CU (1) CU23174A3 (el)
CZ (1) CZ297379B6 (el)
DE (2) DE991766T1 (el)
DK (1) DK0991766T3 (el)
EA (2) EA004652B1 (el)
EE (1) EE04595B1 (el)
ES (1) ES2154624T3 (el)
GE (1) GEP20032871B (el)
GR (1) GR20010300003T1 (el)
HU (1) HU225888B1 (el)
ID (1) ID29311A (el)
IL (3) IL132184A0 (el)
LT (1) LT4706B (el)
LV (1) LV12507B (el)
NO (1) NO324872B1 (el)
NZ (1) NZ500963A (el)
OA (1) OA11219A (el)
PL (1) PL201266B1 (el)
PT (1) PT991766E (el)
RO (1) RO121968B1 (el)
RS (1) RS49677B (el)
SI (1) SI20215B (el)
SK (1) SK161899A3 (el)
TR (1) TR199902728T2 (el)
UA (1) UA72187C2 (el)
WO (1) WO1998056923A1 (el)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586661B1 (en) * 1997-06-12 2003-07-01 North Carolina State University Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid
US20100251425A9 (en) * 1998-05-15 2010-09-30 University Of Central Florida Expression of human interferon in transgenic chloroplasts
DE19926216A1 (de) * 1999-06-09 2001-02-22 Metallgesellschaft Ag Verfahren zur Herstellung von Bariumsulfat, Bariumsulfat und Verwendung des Bariumsulfats
ATE333506T1 (de) * 2000-08-30 2006-08-15 Univ North Carolina State Transgene pflanzen, die molekulare decoys enthalten, die den proteininhalt ändern
CA2427825A1 (en) * 2000-11-07 2002-05-16 North Carolina State University Putrescine-n-methyltransferase promoter
EP1408780A2 (en) 2000-11-10 2004-04-21 Vector Tobacco Ltd. Method and product for removing carcinogens from tobacco smoke
DE10055870A1 (de) * 2000-11-10 2002-05-29 Degussa Neue für das nadC-Gen kodierende Nukleotidsequenzen
CN1288248C (zh) * 2001-06-06 2006-12-06 二十二世纪有限责任公司 烟草生物质的用途
US20060157072A1 (en) * 2001-06-08 2006-07-20 Anthony Albino Method of reducing the harmful effects of orally or transdermally delivered nicotine
WO2005103296A2 (en) * 2004-03-30 2005-11-03 Vector Tobacco, Ltd. Global gene expression analysis of human bronchial epithelial cells exposed to cigarette smoke, smoke condensates, or components thereof
MXPA03011385A (es) * 2001-06-08 2005-03-07 Vector Tobacco Ltd Modeificacion de los niveles de nicotina y nitrosamina en el tabaco.
US6730832B1 (en) 2001-09-10 2004-05-04 Luis Mayan Dominguez High threonine producing lines of Nicotiana tobacum and methods for producing
AU2002340407A1 (en) * 2001-11-09 2003-05-26 Vector Tobacco Inc. Method and composition for mentholation of charcoal filtered cigarettes
WO2003053177A1 (en) * 2001-12-19 2003-07-03 Vector Tobacco Inc. Method and composition for mentholation of cigarettes
JP2005512554A (ja) * 2001-12-19 2005-05-12 ベクター・タバコ・インコーポレーテッド タバコ製品に清涼効果を付与する方法および組成物
JP2005522201A (ja) * 2002-04-09 2005-07-28 ベクター、タバコ、リミテッド ニコチンおよびニトロソアミンを減少させたタバコ
JP2007502621A (ja) * 2003-08-19 2007-02-15 22ンド センチュリー リミテッド,エルエルシー 曝露低減タバコ製品
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
EP1684603A2 (en) * 2003-10-02 2006-08-02 Vector Tobacco Ltd. Tobacco product labeling system
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US7538071B2 (en) 2003-11-21 2009-05-26 Carl Berger Methods of reducing the nicotine content of tobacco plants and tobacco plants obtained thereby
US8792955B2 (en) 2004-05-03 2014-07-29 Dexcom, Inc. Transcutaneous analyte sensor
US9044199B2 (en) 2004-07-13 2015-06-02 Dexcom, Inc. Transcutaneous analyte sensor
AP2014007807A0 (en) 2005-02-28 2014-07-31 22Nd Century Ltd Llc Reducing levels of nicotinic alkaloids in plants
AU2012203977B2 (en) * 2005-02-28 2015-01-29 22Nd Century Limited, Llc Reducing levels of nicotinic alkaloids in plants
NZ564025A (en) 2005-05-11 2012-03-30 Vector Tobacco Inc Reduced risk tobacco products and methods of making same
FR2889003A1 (fr) * 2005-07-22 2007-01-26 St Microelectronics Sa Adaptation automatique d'une source video a un recepteur
CA2853387C (en) 2006-06-19 2018-04-17 National Research Council Of Canada Nucleic acid encoding n-methylputrescine oxidase and uses thereof
ES2478633T3 (es) 2006-09-13 2014-07-22 22Nd Century Limited, Llc Aumento de los niveles de alcaloides nicotínicos
US9551003B2 (en) 2006-09-13 2017-01-24 22Nd Century Limited, Llc Increasing levels of nicotinic alkaloids in plants
US9102948B2 (en) 2006-11-17 2015-08-11 22Nd Century Limited, Llc Regulating alkaloids
US9106606B1 (en) 2007-02-05 2015-08-11 F5 Networks, Inc. Method, intermediate device and computer program code for maintaining persistency
CN104911204B (zh) 2007-05-25 2019-01-01 22世纪有限责任公司 编码调节生物碱合成之转录因子的核酸序列及其在改良植物代谢中的应用
US20100206317A1 (en) * 2007-09-28 2010-08-19 Vector Tobacco, Inc. Reduced risk tobacco products and use thereof
EP2231861B1 (en) * 2007-12-13 2014-10-29 Philip Morris Products S.A. Transgenic plants modified for reduced cadmium transport, derivative products, and related methods
EP2508603B1 (en) 2009-11-19 2015-05-13 National University Corporation Okayama University System for increasing gene expression, and vector supporting said system
EP2509656B1 (en) 2009-12-11 2015-03-25 Terumo BCT, Inc. System for blood separation with shielded extraction port and optical control
JP5540068B2 (ja) 2010-02-17 2014-07-02 日本たばこ産業株式会社 植物内容成分の調節因子、およびその利用
US9862923B2 (en) 2010-03-26 2018-01-09 Philip Morris Usa Inc. Cultured tobacco cells as a matrix for consumable products
EP2565265A1 (en) 2011-09-02 2013-03-06 Philip Morris Products S.A. Isopropylmalate synthase from Nicotiana tabacum and methods and uses thereof
US8716571B2 (en) 2011-09-21 2014-05-06 Reynolds Technologies, Inc. Tobacco having reduced amounts of amino acids and methods for producing such lines
US9137958B2 (en) 2012-02-08 2015-09-22 Reynolds Technologies, Inc. Tobacco having altered amounts of environmental contaminants
RU2735254C2 (ru) * 2012-12-21 2020-10-29 Филип Моррис Продактс С.А. Снижение табак-специфичных нитрозаминов в растениях
CN103173488B (zh) * 2013-03-14 2014-09-03 浙江省农业科学院 新的融合标签进行水稻转基因快速筛选的方法
US10375910B2 (en) 2013-03-15 2019-08-13 Altria Client Services Llc Development of tobacco varieties with no or significantly reduced anatabine content
JP2018516550A (ja) * 2015-05-05 2018-06-28 ノース カロライナ ステート ユニバーシティNorth Carolina State University タバコ中のタバコ特異的ニトロソアミンnnkを低減するための方法及び組成物
EP4218404A3 (en) 2015-06-26 2023-09-06 Altria Client Services LLC Compositions and methods for producing tobacco plants and products having altered alkaloid levels
EP3480314A1 (en) 2017-11-03 2019-05-08 Philip Morris Products S.A. Regulation of alkaloid content
US20200035118A1 (en) 2018-07-27 2020-01-30 Joseph Pandolfino Methods and products to facilitate smokers switching to a tobacco heating product or e-cigarettes
US10897925B2 (en) 2018-07-27 2021-01-26 Joseph Pandolfino Articles and formulations for smoking products and vaporizers
JP2022552261A (ja) * 2019-10-10 2022-12-15 アルトリア クライアント サーヴィシーズ リミテッド ライアビリティ カンパニー 変化したアルカロイドレベルを有するタバコ植物およびタバコ製品を作製するためのqpt操作に基づく組成物および方法
CN113528537A (zh) * 2021-08-11 2021-10-22 云南省烟草农业科学研究院 一种降低烟叶烟碱含量的NtQPT2基因突变体及其应用
CN116983432A (zh) * 2023-07-07 2023-11-03 深圳先进技术研究院 用于治疗类风湿性关节炎的药物

Family Cites Families (216)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US38123A (en) * 1863-04-07 Improvement in harvesters
US254285A (en) 1882-02-28 David w
US299541A (en) 1884-06-03 heae-n
US819751A (en) * 1905-01-04 1906-05-08 Giuseppe Gianoli Process of charging silk.
US2479526A (en) 1940-12-11 1949-08-16 Wurton Machine Company Apparatus for curing green tobacco
US2728803A (en) * 1951-12-28 1955-12-27 Standard Oil Co Separation of ethylbenzene from other c8 aromatic hydrocarbons by extraction with hf-bf3
US2728603A (en) 1954-12-13 1955-12-27 James H Stagg Lawn and garden sprinkler
DE1917552U (de) 1964-01-31 1965-06-10 Fritz Tautenhahn Flaechig-ornamentales gitterwerk.
US3693631A (en) 1971-04-28 1972-09-26 Reynolds Leasing Corp Tobacco expansion process
US3840025A (en) 1972-08-14 1974-10-08 Industrial Nucleonics Corp Tobacco moisture control system and method
US3905123A (en) 1973-10-15 1975-09-16 Industrial Nucleonics Corp Method and apparatus for controlling a tobacco dryer
US4319587A (en) 1975-06-09 1982-03-16 Irving S. Moser Smoking article
DE2531285C2 (de) 1975-07-12 1982-10-28 Deutsche Benkert Gmbh & Co Kg, 4690 Herne Filterzigarette
US4192323A (en) 1977-09-21 1980-03-11 Gas-Fired Products, Inc. Apparatus and method for automatically controlling curing conditions in a tobacco curing barn
US4557280A (en) 1978-06-15 1985-12-10 Brown & Williamson Tobacco Corporation Process for reduction of nitrate and nicotine content of tobacco by microbial treatment
US4243056A (en) 1979-01-12 1981-01-06 Philip Morris Incorporated Method for uniform incorporation of additives into tobacco
FR2478958A1 (fr) 1980-04-01 1981-10-02 Decoufle Dispositif d'alimentation en encre des appareils d'imprimerie pour machines a confectionner les cigarettes
US4499911A (en) 1980-12-09 1985-02-19 Johnson William H Energy efficient curing and drying system
GB2092149B (en) * 1981-02-03 1985-01-03 Searle & Co Imidazoline hydrazone and hydrazine derivatives production thereof and use in medicine
US4459355A (en) 1982-07-12 1984-07-10 International Paper Company Method for transforming plant cells
US4762785A (en) 1982-08-12 1988-08-09 Calgene, Inc. Novel method and compositions for introducting alien DNA in vivo
NL8203963A (nl) 1982-10-14 1984-05-01 Naarden International Nv Werkwijze voor het aromatiseren van droog plantaardig materiaal.
EP0320500B1 (en) 1983-01-13 2004-11-17 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Non-oncogenic ti plasmid vector system and recombinant DNA molecules for the introduction of expressible genes into plant cell genomes
US6051757A (en) 1983-01-14 2000-04-18 Washington University Regeneration of plants containing genetically engineered T-DNA
EP0131623B2 (en) 1983-01-17 1999-07-28 Monsanto Company Chimeric genes suitable for expression in plant cells
US5352605A (en) 1983-01-17 1994-10-04 Monsanto Company Chimeric genes for transforming plant cells using viral promoters
US6174724B1 (en) 1983-01-17 2001-01-16 Monsanto Company Chimeric genes suitable for expression in plant cells
US5034322A (en) 1983-01-17 1991-07-23 Monsanto Company Chimeric genes suitable for expression in plant cells
WO1984002919A1 (en) 1983-01-17 1984-08-02 Monsanto Co Plasmids for transforming plant cells
WO1984002920A1 (en) 1983-01-17 1984-08-02 Monsanto Co Genetically transformed plants
NL8300699A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; werkwijze voor het produceren van agrobacterium tumefaciens bacterien; stabiele cointegraat plasmiden; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
US4751348A (en) 1983-07-16 1988-06-14 Cold Spring Harbor Laboratory Nicotiana plants with both altered polyamine levels and flower structures and method for obtaining these plants
US4766855A (en) * 1983-07-20 1988-08-30 Cummins Engine Co., Inc. Plasma jet ignition apparatus
US5190931A (en) 1983-10-20 1993-03-02 The Research Foundation Of State University Of New York Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA
US5208149A (en) 1983-10-20 1993-05-04 The Research Foundation Of State University Of New York Nucleic acid constructs containing stable stem and loop structures
DE3486479T2 (de) 1983-10-20 2001-09-20 The Research Foundation Of State University Of New York, Albany Regulierung der Genexpression durch Translationshemmung unter Verwendung von mRNA hindernder Komplementär-RNA
US5272065A (en) 1983-10-20 1993-12-21 Research Foundation Of State University Of New York Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA
US4885248A (en) 1984-02-15 1989-12-05 Lubrizol Genetics, Inc. Transfer vector
US4771002A (en) 1984-02-24 1988-09-13 Lubrizol Genetics, Inc. Transcription in plants and bacteria
US5149645A (en) 1984-06-04 1992-09-22 Rijksuniversiteit Leiden Process for introducing foreign DNA into the genome of plants
NL8401780A (nl) 1984-06-04 1986-01-02 Rijksuniversiteit Leiden En Pr Werkwijze voor het inbouwen van vreemd dna in het genoom van planten.
US5036006A (en) 1984-11-13 1991-07-30 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5100792A (en) 1984-11-13 1992-03-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues
ATE93542T1 (de) 1984-12-28 1993-09-15 Plant Genetic Systems Nv Rekombinante dna, die in pflanzliche zellen eingebracht werden kann.
US6281410B1 (en) 1986-07-31 2001-08-28 Calgene Llc Methods and compositions for regulated transcription and expression of heterologous genes
US4943674A (en) 1987-05-26 1990-07-24 Calgene, Inc. Fruit specific transcriptional factors
US5753475A (en) 1985-01-17 1998-05-19 Calgene, Inc. Methods and compositions for regulated transcription and expression of heterologous genes
US6617496B1 (en) 1985-10-16 2003-09-09 Monsanto Company Effecting virus resistance in plants through the use of negative strand RNAs
NL8502948A (nl) 1985-10-29 1987-05-18 Rijksuniversiteit Leiden En Pr Werkwijze voor het inbouwen van "vreemd dna" in het genoom van dicotyle planten.
US4795855A (en) 1985-11-14 1989-01-03 Joanne Fillatti Transformation and foreign gene expression with woody species
GB8529851D0 (en) 1985-12-04 1986-01-15 Rothmans Of Pall Mall Linear layered cigarette
US5107065A (en) 1986-03-28 1992-04-21 Calgene, Inc. Anti-sense regulation of gene expression in plant cells
NZ219472A (en) 1986-03-28 1990-08-28 Calgene Inc Regulation of phenotype in plant cells using dsdna constructs
US5453566A (en) 1986-03-28 1995-09-26 Calgene, Inc. Antisense regulation of gene expression in plant/cells
US4700725A (en) 1986-04-17 1987-10-20 Philip Morris Incorporated Adjustable filter cigarette
US4699158A (en) 1986-04-17 1987-10-13 Philip Morris Incorporated Adjustable filter cigarette with tactile indicator
DE3661587D1 (en) 1986-04-23 1989-02-09 Reynolds Tobacco Gmbh Process for treating tobacco and similar organic materials
US4766911A (en) 1986-06-23 1988-08-30 R. J. Reynolds Tobacco Company Method for tracing smoking articles
US4962028A (en) 1986-07-09 1990-10-09 Dna Plant Technology Corporation Plant promotors
US5229292A (en) 1986-07-28 1993-07-20 Stine Seed Farm, Inc. Biological control of insects using pseudomonas strains transformed with bacillus thuringiensis insect toxingene
EP0265556A1 (en) 1986-10-31 1988-05-04 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Stable binary agrobacterium vectors and their use
US5268463A (en) 1986-11-11 1993-12-07 Jefferson Richard A Plant promoter α-glucuronidase gene construct
US5015580A (en) 1987-07-29 1991-05-14 Agracetus Particle-mediated transformation of soybean plants and lines
US4966916A (en) 1987-02-12 1990-10-30 Abood Leo G Agonists and antagonists to nicotine as smoking deterrents
US4835162A (en) 1987-02-12 1989-05-30 Abood Leo G Agonists and antagonists to nicotine as smoking deterents
US5356799A (en) 1988-02-03 1994-10-18 Pioneer Hi-Bred International, Inc. Antisense gene systems of pollination control for hybrid seed production
US5922602A (en) 1988-02-26 1999-07-13 Biosource Technologies, Inc. Cytoplasmic inhibition of gene expression
US5179022A (en) 1988-02-29 1993-01-12 E. I. Du Pont De Nemours & Co. Biolistic apparatus for delivering substances into cells and tissues in a non-lethal manner
US4954442A (en) 1988-08-31 1990-09-04 Purdue Research Foundation Opine enhancement of vir gene induction
US5023179A (en) 1988-11-14 1991-06-11 Eric Lam Promoter enhancer element for gene expression in plant roots
GB8827592D0 (en) 1988-11-25 1988-12-29 Taniguchi T Improvements in & relating to regulation of expression
US5223419A (en) 1989-03-14 1993-06-29 The Rockefeller University Alteration of gene expression in plants
US4990607A (en) 1989-03-14 1991-02-05 The Rockefeller University Alteration of gene expression in plants
US5034323A (en) 1989-03-30 1991-07-23 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5231020A (en) 1989-03-30 1993-07-27 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
GB8916213D0 (en) 1989-07-14 1989-08-31 Ici Plc Dna constructs,cells and plants derived therefrom
US5665543A (en) 1989-07-18 1997-09-09 Oncogene Science, Inc. Method of discovering chemicals capable of functioning as gene expression modulators
US6203976B1 (en) 1989-07-18 2001-03-20 Osi Pharmaceuticals, Inc. Methods of preparing compositions comprising chemicals capable of transcriptional modulation
US5776502A (en) 1989-07-18 1998-07-07 Oncogene Science, Inc. Methods of transcriptionally modulating gene expression
EP0483249B1 (en) 1989-07-18 2003-04-23 OSI Pharmaceuticals, Inc. Method of transcriptionally modulating gene expression and of discovering chemicals capable of functioning as gene expression modulators
US5580722A (en) 1989-07-18 1996-12-03 Oncogene Science, Inc. Methods of determining chemicals that modulate transcriptionally expression of genes associated with cardiovascular disease
NL8901931A (nl) 1989-07-26 1991-02-18 Mogen International N V En Rij Werkwijze voor het plaatsgericht introduceren van vreemd dna in het genoom van planten.
US5501967A (en) 1989-07-26 1996-03-26 Mogen International, N.V./Rijksuniversiteit Te Leiden Process for the site-directed integration of DNA into the genome of plants
US5097025A (en) 1989-08-01 1992-03-17 The Rockefeller University Plant promoters
US5062434A (en) 1989-09-22 1991-11-05 Brown & Williamson Tobacco Corporation Cigarette paper
GB8923716D0 (en) 1989-10-20 1989-12-06 Ici Plc Dna,constructs,cells and plants derived therefrom
US5177308A (en) 1989-11-29 1993-01-05 Agracetus Insecticidal toxins in plants
ATE130371T1 (de) 1989-12-19 1995-12-15 Ciba Geigy Ag Verfahren und vorrichtung zur genetischen transformation von zellen.
JPH0673478B2 (ja) * 1990-01-11 1994-09-21 旭化成工業株式会社 L―カルニチンの高感度測定法および測定用組成物
WO1991011535A1 (en) 1990-01-30 1991-08-08 Childrens Hospital Of Los Angeles Inhibition of transcription by double-stranded oligonucleotides
CA2036935A1 (en) 1990-02-26 1991-08-27 Paul Christou Plant transformation process with early identification of germ line transformation events
GB9005945D0 (en) 1990-03-16 1990-05-09 Cambridge Advanced Tech Plant promoter
WO1991014790A1 (en) 1990-03-27 1991-10-03 New England Medical Center Hospitals, Inc. Inhibitors of transcription activation activity of papillomaviruses
US5109876A (en) 1990-04-19 1992-05-05 R. J. Reynolds Tobacco Company Cigarette paper and cigarette incorporating same
US5204253A (en) 1990-05-29 1993-04-20 E. I. Du Pont De Nemours And Company Method and apparatus for introducing biological substances into living cells
US5932782A (en) 1990-11-14 1999-08-03 Pioneer Hi-Bred International, Inc. Plant transformation method using agrobacterium species adhered to microprojectiles
US5260205A (en) 1990-11-14 1993-11-09 Philip Morris Incorporated Method of purifying putrescine N-methyltransferase from tobacco plant extract with a polyamine
US5668295A (en) 1990-11-14 1997-09-16 Philip Morris Incorporated Protein involved in nicotine synthesis, DNA encoding, and use of sense and antisense DNAs corresponding thereto to affect nicotine content in transgenic tobacco cells and plants
US5035252A (en) 1990-12-14 1991-07-30 Mondre Steven J Nicotine-containing dental floss
US5459252A (en) 1991-01-31 1995-10-17 North Carolina State University Root specific gene promoter
JPH04265569A (ja) * 1991-02-19 1992-09-21 Canon Inc 音声信号記録装置及び再生装置
AU663702B2 (en) 1991-03-06 1995-10-19 Board Of Regents, The University Of Texas System Methods and compositions for the selective inhibition of gene expression
US5683985A (en) 1991-04-18 1997-11-04 The Salk Institute For Biological Studies Oligonucleotide decoys and methods relating thereto
FR2675803B1 (fr) 1991-04-25 1996-09-06 Genset Sa Oligonucleotides fermes, antisens et sens et leurs applications.
GB9109063D0 (en) 1991-04-26 1991-06-12 Ici Plc Modification of lignin synthesis in plants
WO1993000546A1 (en) 1991-06-20 1993-01-07 Reinforced Plastics/Composites Pty Ltd A connecting system
ATE165397T1 (de) 1991-06-27 1998-05-15 Genelabs Tech Inc Screeningtest für den nachweis von dna-bindenden molekülen
US5994629A (en) 1991-08-28 1999-11-30 Novartis Ag Positive selection
GB9304200D0 (en) 1993-03-02 1993-04-21 Sandoz Ltd Improvements in or relating to organic compounds
DK152291D0 (da) 1991-08-28 1991-08-28 Danisco Fremgangsmaade og kemiske forbindelser
WO1993005646A1 (en) * 1991-09-13 1993-04-01 Technology Management Services, S.A. Reduction of nicotine levels in tobacco
AU3584993A (en) 1992-01-27 1993-09-01 Trustees Of The University Of Pennsylvania, The Methods and compositions for neutralizing intracellular nucleic acid-binding protein biological activity in a cell, including methods and compositions useful to regulate gene function
US5635381A (en) 1992-02-26 1997-06-03 Mogen International Nv Agrobacterium bacteria capable of site-specific recombination
US5780051A (en) 1992-04-02 1998-07-14 Dynagen, Inc. Methods and articles of manufacture for nicotine cessation and monitoring nicotine use
AU678154B2 (en) 1992-04-02 1997-05-22 Sembiosys Genetics Inc. Oil-body protein cis-elements as regulatory signals
US5626152A (en) 1992-08-26 1997-05-06 Molins Plc Cigarette making machine
US5469871A (en) 1992-09-17 1995-11-28 R. J. Reynolds Tobacco Company Cigarette and method of making same
DE69327809T2 (de) 1992-11-27 2000-10-12 Voxel, Laguna Hills Verfahren und vorrichtung zur herstellung von hologrammen
WO1994012015A1 (en) 1992-11-30 1994-06-09 Chua Nam Hai Expression motifs that confer tissue- and developmental-specific expression in plants
IL108367A0 (en) 1993-01-27 1994-04-12 Hektoen Inst For Medical Resea Antisense polynzcleotide inhibition of human growth factor-sensitive cancer cells
ES2161245T3 (es) 1993-05-13 2001-12-01 Aventis Cropscience Nv Gen marcador.
KR960702865A (ko) * 1993-06-01 1996-05-23 에이. 스테판 로버츠 퓨트레신 n-메틸트랜스퍼라제와, 이를 코딩하는 재조합 dna 분자 및 알칼로이드 함량이 감소된 유전자 변이된 담배 식물(putrescine n-methyltransfera-se, recombinant dna molecules encoding putrescine n-methyltranferase, and transgenic tobacco plants with decreased alkaloid content)
US5540242A (en) 1993-07-07 1996-07-30 Brown & Williamson Tobacco Corporation Cigarette paper having reduced sidestream properties
US5377697A (en) 1993-08-27 1995-01-03 Hoechst Celanese Corporation Cigarette filter test apparatus and associated method for measuring filter hot collapse and tobacco consumption
US5810020A (en) 1993-09-07 1998-09-22 Osmotek, Inc. Process for removing nitrogen-containing anions and tobacco-specific nitrosamines from tobacco products
EP1350514A3 (en) 1993-10-29 2004-07-07 The Brigham And Women's Hospital, Inc. Therapeutic use of cis-element decoys in vivo
US6399376B1 (en) 1993-11-05 2002-06-04 Isis Pharmaceuticals, Inc. Modulation of vascular cell adhesive molecule expression through oligonucleotide interactions
JP3102888B2 (ja) 1993-12-08 2000-10-23 日本たばこ産業株式会社 植物の形質転換方法及びそのためのベクター
US5394894A (en) 1994-02-22 1995-03-07 Zade; Ismail Y. Method and apparatus for elimination of smoking
ES2081257B1 (es) 1994-05-12 1996-07-16 Sagrera Jorge Martinez Instalacion y procedimiento para el curado de tabaco.
US5858774A (en) 1994-05-12 1999-01-12 The Research Foundation Of State University Of New York Antisense DNA constructs for expression of hybrid MRNAs driven by inducible, tissue-specific promoters
US5750870A (en) 1994-06-17 1998-05-12 Agritope, Inc. Plant genetic transformation methods and transgenic plants
JP3235934B2 (ja) 1994-08-04 2001-12-04 三菱レイヨン株式会社 ロドコッカス属細菌由来カナマイシン耐性遺伝子
IT1275697B1 (it) 1994-12-20 1997-10-17 Olmo Giancarlo Dell Metodo per stampare direttamente su carta microincisioni di ologrammi,chinogrammi,reticoli di diffrazione o microincisioni
US5733744A (en) 1995-01-13 1998-03-31 Cornell Research Foundation, Inc. Binary BAC vector
WO1996029418A1 (en) 1995-03-22 1996-09-26 Novo Nordisk A/S Introduction of dna into bacillus strains by conjugation
EP0818532B1 (en) 1995-03-30 2005-11-16 Takara Bio Inc. Plant promoter and gene expression with the use of the same
EP0824918B1 (en) 1995-05-12 2007-03-28 AnGes MG, Inc. REMEDY AND PREVENTIVE FOR DISEASES CAUSED BY NF-kappaB
US5837876A (en) * 1995-07-28 1998-11-17 North Carolina State University Root cortex specific gene promoter
GB9517263D0 (en) 1995-08-23 1995-10-25 Cancer Res Campaign Tech Expression systems
PL191113B1 (pl) 1995-09-25 2006-03-31 Syngenta Participations Ag Sposób integrowania interesującego DNA z genomem komórki roślinnej, sposób wytwarzania płodnej transgenicznej rośliny z genomem mającym wintegrowany DNA, zastosowanie genu kodującego białka wirulencji Agrobacterium w niebiologicznych sposobach transformacji komórek roślinnych, transgeniczna komórka roślinna, roślina regenerowana z komórki roślinnej oraz potomstwo roślin otrzymanych ze zregenerowanej komórki roślinnej
US6051409A (en) 1995-09-25 2000-04-18 Novartis Finance Corporation Method for achieving integration of exogenous DNA delivered by non-biological means to plant cells
US6198827B1 (en) * 1995-12-26 2001-03-06 Rocktron Corporation 5-2-5 Matrix system
US5693512A (en) 1996-03-01 1997-12-02 The Ohio State Research Foundation Method for transforming plant tissue by sonication
CA2251738A1 (en) 1996-04-16 1997-10-23 Immusol Incorporated Targeted viral vectors
US5851804A (en) 1996-05-06 1998-12-22 Apollon, Inc. Chimeric kanamycin resistance gene
US5713376A (en) 1996-05-13 1998-02-03 Berger; Carl Non-addictive tobacco products
DE69738454D1 (de) 1996-05-20 2008-02-21 Us Gov Health & Human Serv Oligonukleotide welche spezifisch retrovirale nukleokapsid-proteine binden
US6022863A (en) 1996-05-21 2000-02-08 Yale University Regulation of gene expression
US5834236A (en) 1996-06-27 1998-11-10 The Salk Institute For Biological Studies AATT repeat transcription enhancer element
US5803081A (en) 1996-06-28 1998-09-08 Regent Court Technologies Tobacco and related products
US6135121A (en) 1996-06-28 2000-10-24 Regent Court Technologies Tobacco products having reduced nitrosamine content
US5845647A (en) 1996-06-28 1998-12-08 Regent Court Technologies Tobacco and related products
USRE38123E1 (en) 1996-06-28 2003-05-27 Regent Court Technologies, Llc. Tobacco products having reduced nitrosamine content
US6037525A (en) 1996-08-01 2000-03-14 North Carolina State University Method for reducing expression variability of transgenes in plant cells
US5830318A (en) 1996-10-25 1998-11-03 Schweitzer-Mauduit International, Inc. High opacity tipping paper
US5929306A (en) 1996-11-15 1999-07-27 University Of Kentucky Research Foundation KYRT1, a disarmed version of a highly tumorigenic Agrobacterium tumefaciens strain identified as Chry5
US6202649B1 (en) 1996-12-02 2001-03-20 Regent Court Technologies Method of treating tobacco to reduce nitrosamine content, and products produced thereby
US6096947A (en) 1997-01-14 2000-08-01 Pioneer Hi-Bred International, Inc. Methods for improving transformation efficiency
AU5918398A (en) 1997-01-28 1998-08-18 Ribozyme Pharmaceuticals, Inc. Compositions and method for modulation of alkaloid biosynthesis and flower formation in plants
US6166032A (en) 1997-02-07 2000-12-26 Synapse Pharmaceuticals International, Inc. Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use
ES1036967Y (es) * 1997-04-15 1998-05-01 Techpack Espana S L Cazoleta perfeccionada para estuche de lapiz de labios.
US6163521A (en) * 1997-04-16 2000-12-19 Matsushita Electric Industrial Co., Ltd. Disk having read-only and read-write areas
US6020989A (en) * 1997-05-14 2000-02-01 Affinity Co., Ltd. Laminated bodies and windows using them
US6586661B1 (en) 1997-06-12 2003-07-01 North Carolina State University Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid
AR015873A1 (es) 1997-06-13 2001-05-30 Shell Int Research Un proceso para producir material vegetal modificado geneticamente que comprende una o mas secuencias de adn de interes establemente incorporadas
US6020969A (en) 1997-07-11 2000-02-01 Philip Morris Incorporated Cigarette making machine including band inspection
US6641996B1 (en) 1997-09-09 2003-11-04 Cambia Microbial β-glucuronidase genes, gene products and uses thereof
US6391547B1 (en) 1997-09-09 2002-05-21 Center For The Application Of Molecular Biology To International Agriculture Microbial β-glucuronidase genes, gene products and uses thereof
CN1188525C (zh) 1997-08-25 2005-02-09 纽海姆·泽登有限公司 改良的农杆菌介导的植物转化
ZA988332B (en) 1997-09-12 1999-03-23 Performance Plants Inc In planta transformation of plants
CA2248622A1 (en) 1997-09-23 1999-03-23 Joe Celeste Biolistic apparatus for delivering substances into cells and tissues
DE69811378T2 (de) 1997-10-03 2004-02-12 Cary Pharmaceuticals Inc. (n.d.Ges.d. Staates Delaware) Zusammensetzungen zur behandlung von nikotinabhängigkeit, enthaltend mecamylamin und bupropion
US6077992A (en) 1997-10-24 2000-06-20 E. I. Du Pont De Nemours And Company Binary viral expression system in plants
EP1032693A1 (en) 1997-11-18 2000-09-06 Pioneer Hi-Bred International, Inc. A method for directional stable transformation of eukaryotic cells
US6060310A (en) 1997-11-24 2000-05-09 The United States Of America As Represented By The Department Of Health And Human Services Transcription factor decoy and tumor growth inhibitor
US6153811A (en) 1997-12-22 2000-11-28 Dekalb Genetics Corporation Method for reduction of transgene copy number
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
US6265538B1 (en) * 1998-02-27 2001-07-24 The Regents Of The University Of California Inhibitor of the inflammatory response induced by the TNFA and IL-1
CA2323726C (en) 1998-03-20 2005-02-08 Benitec Australia Ltd. Control of gene expression
JP3444191B2 (ja) 1998-03-31 2003-09-08 日本製紙株式会社 フェニルプロパノイド生合成経路を制御する転写因子
JP5015373B2 (ja) 1998-04-08 2012-08-29 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガニゼイション 改良表現型を得るための方法及び手段
US6136799A (en) 1998-04-08 2000-10-24 Abbott Laboratories Cosolvent formulations
US5938017A (en) 1998-05-04 1999-08-17 Wik; Dennis O. Article for assisting persons to quit smoking and method for same
AR020078A1 (es) 1998-05-26 2002-04-10 Syngenta Participations Ag Metodo para alterar la expresion de un gen objetivo en una celula de planta
CA2334186A1 (en) 1998-06-05 1999-12-09 Regent Court Technologies Monoamine oxidase (mao) inhibitors and uses thereof
US6271031B1 (en) 1998-08-12 2001-08-07 E.I. Du Pont De Nemours And Company Quinolinate metabolism enzymes
AU5796099A (en) 1998-08-31 2000-03-21 Monsanto Company A new method of identifying non-host plant disease resistance genes
US6265638B1 (en) 1998-10-01 2001-07-24 Pioneer Hi-Bred International, Inc. Method of plant transformation
DE19847767A1 (de) 1998-10-16 2000-04-20 Decoufle Sarl Anordnung zum Zuführen von fließfähiger Druckfarbe zu einem Druckwerk für einen Zigarettenpapierstreifen
DE19852757A1 (de) 1998-11-16 2000-05-18 Eth Zuerich Zuerich Promotoren zur Genexpression in Wurzeln von Pflanzen
DE69924005T2 (de) 1998-12-22 2006-04-13 National Research Council Canada, Ottawa Transgene pflanzen mit konditional lethalem gen
JP2002533090A (ja) 1998-12-23 2002-10-08 ザ、サミュアル、ラバツ、ノゥブル、ファウンデイシャン、インク 植物形質転換法
PL202067B1 (pl) 1999-04-19 2009-05-29 Biogemma S A S Sposoby transformacji roślin oraz zastosowanie Agrobacterium w sposobie transformacji
AU4991500A (en) 1999-05-06 2000-11-21 Michael Timko Regulation of gene expression in tobacco for manipulation of plant growth and secondary metabolism
US6603061B1 (en) 1999-07-29 2003-08-05 Monsanto Company Agrobacterium-mediated plant transformation method
US6314964B1 (en) 1999-09-15 2001-11-13 Schweitzer-Mauduit International, Inc. Cigarette paper containing carbon fibers for improved ash characteristics
US6809232B1 (en) 1999-11-29 2004-10-26 Midwest Oilseeds, Inc. Methods and compositions for the introduction of molecules into cells
EP1238090B1 (en) 1999-12-16 2007-05-09 CropDesign N.V. Optimized t-dna transfer and vectors therefor
US20050229272A1 (en) 1999-12-30 2005-10-13 Monica Driscoll Compositions and methods for gene silencing
AU2778801A (en) 2000-01-07 2001-07-24 Baylor University Antisense compositions and methods
JP2003526367A (ja) 2000-03-16 2003-09-09 ジェネティカ インコーポレイテッド Rna干渉の方法とrna干渉組成物
AU2001253255A1 (en) 2000-04-07 2001-10-23 Large Scale Biology Corporation Compositions and methods for inhibiting gene expression
WO2002000926A2 (en) 2000-06-30 2002-01-03 Epigenomics Ag Diagnosis of diseases associated with signal transduction
ATE333506T1 (de) 2000-08-30 2006-08-15 Univ North Carolina State Transgene pflanzen, die molekulare decoys enthalten, die den proteininhalt ändern
CA2427825A1 (en) 2000-11-07 2002-05-16 North Carolina State University Putrescine-n-methyltransferase promoter
CN1288248C (zh) 2001-06-06 2006-12-06 二十二世纪有限责任公司 烟草生物质的用途
US20060157072A1 (en) 2001-06-08 2006-07-20 Anthony Albino Method of reducing the harmful effects of orally or transdermally delivered nicotine
MXPA03011385A (es) 2001-06-08 2005-03-07 Vector Tobacco Ltd Modeificacion de los niveles de nicotina y nitrosamina en el tabaco.
US6557560B2 (en) 2001-06-18 2003-05-06 Ctc Canada Inc. Cigarette making machine
JP2007502621A (ja) 2003-08-19 2007-02-15 22ンド センチュリー リミテッド,エルエルシー 曝露低減タバコ製品
AP2014007807A0 (en) 2005-02-28 2014-07-31 22Nd Century Ltd Llc Reducing levels of nicotinic alkaloids in plants
CA2853387C (en) 2006-06-19 2018-04-17 National Research Council Of Canada Nucleic acid encoding n-methylputrescine oxidase and uses thereof
EP2087123B1 (en) 2006-10-13 2011-08-10 North Carolina State University Alteration of tobacco alkaloid content through modification of specific cytochrome p450 genes

Also Published As

Publication number Publication date
OA11219A (en) 2003-07-17
US7304220B2 (en) 2007-12-04
CN1257542A (zh) 2000-06-21
KR100365969B1 (ko) 2002-12-26
JP4459271B2 (ja) 2010-04-28
EP0991766A1 (en) 2000-04-12
AU748514B2 (en) 2002-06-06
KR20010013663A (ko) 2001-02-26
US6423520B1 (en) 2002-07-23
CU23174A3 (es) 2006-09-22
EA200400186A1 (ru) 2004-08-26
DK0991766T3 (da) 2004-07-12
HK1069411A1 (en) 2005-05-20
BG103886A (en) 2000-07-31
US20020108151A1 (en) 2002-08-08
US20060200872A1 (en) 2006-09-07
LT99142A (en) 2000-06-26
RO121968B1 (ro) 2008-09-30
WO1998056923A1 (en) 1998-12-17
YU64899A (sh) 2004-12-31
ES2154624T3 (es) 2004-11-01
CN100482799C (zh) 2009-04-29
HK1027379A1 (en) 2001-01-12
CA2484366A1 (en) 1998-12-17
EE04595B1 (et) 2006-02-15
US20040168211A1 (en) 2004-08-26
JP2009112316A (ja) 2009-05-28
AP1169A (en) 2003-06-30
EP1457562A1 (en) 2004-09-15
EP0991766B1 (en) 2004-03-17
US7645925B2 (en) 2010-01-12
SI20215A (sl) 2000-10-31
JP2004290201A (ja) 2004-10-21
TR199902728T2 (xx) 2000-09-21
NO996169D0 (no) 1999-12-13
AP9901680A0 (en) 1999-12-31
US7408098B2 (en) 2008-08-05
PL337442A1 (en) 2000-08-14
US7425670B2 (en) 2008-09-16
CZ367799A3 (cs) 2000-04-12
JP2008131950A (ja) 2008-06-12
CN1618972A (zh) 2005-05-25
SI20215B (sl) 2007-04-30
NO996169L (no) 1999-12-13
ATE262039T1 (de) 2004-04-15
DE69822463T2 (de) 2005-01-20
LT4706B (lt) 2000-09-25
US20060191036A1 (en) 2006-08-24
UA72187C2 (uk) 2005-02-15
BG64319B1 (bg) 2004-09-30
IL132184A0 (en) 2001-03-19
US6586661B1 (en) 2003-07-01
JP4095678B2 (ja) 2008-06-04
PL201266B1 (pl) 2009-03-31
US20060191035A1 (en) 2006-08-24
US7605308B2 (en) 2009-10-20
BRPI9810870B1 (pt) 2021-06-01
JP4288206B2 (ja) 2009-07-01
ID29311A (id) 2001-08-16
EP1457563A1 (en) 2004-09-15
GEP20032871B (en) 2003-01-27
DE69822463D1 (de) 2004-04-22
EP1457563B1 (en) 2012-08-08
CA2287776C (en) 2012-04-03
RS49677B (sr) 2007-11-15
JP2001522250A (ja) 2001-11-13
US7795509B2 (en) 2010-09-14
AU7829198A (en) 1998-12-30
HK1065066A1 (en) 2005-02-08
IL192232A0 (en) 2008-12-29
US20030140366A1 (en) 2003-07-24
EA200000007A1 (ru) 2000-06-26
EA009898B1 (ru) 2008-04-28
NZ500963A (en) 2001-09-28
NO324872B1 (no) 2007-12-17
EP1457562B1 (en) 2012-08-08
BR9810870A (pt) 2000-11-14
LV12507A (en) 2000-06-20
CA2287776A1 (en) 1998-12-17
CN1304576C (zh) 2007-03-14
CZ297379B6 (cs) 2006-11-15
LV12507B (en) 2000-11-20
IL132184A (en) 2010-11-30
EA004652B1 (ru) 2004-06-24
SK161899A3 (en) 2000-06-12
HU225888B1 (en) 2007-11-28
US20070011774A1 (en) 2007-01-11
ES2154624T1 (es) 2001-04-16
HUP0003767A3 (en) 2002-10-28
PT991766E (pt) 2004-08-31
EE9900575A (et) 2000-08-15
HUP0003767A2 (hu) 2001-02-28
DE991766T1 (de) 2002-04-04

Similar Documents

Publication Publication Date Title
IL192232A0 (en) Regulation of quinolate phosphoribosyl transferase expression
HUP0101225A3 (en) Control of gene expression
IL141471A0 (en) Regulation of substrate activity
PL339551A1 (en) Derivatives of rezorcin
PL339574A1 (en) Polymeric derivatives of camptotectin
PL338563A1 (en) Substituted derivatives of 1,2,3,4-tetrahydronaphtalene
EP1045844A4 (en) INHIBITORS OF FARNESYL PROTEIN TRANSFERASE
PL338144A1 (en) Derivatives of dolastatin 15
EP1049797A4 (en) REGULATION OF GENE EXPRESSION IN MUSHROOMS
PL348428A1 (en) Genes of the 1-desoxy-d-xylulose biosynthetic pathway
NO983775D0 (no) Regulering av gen-ekspresjon i eukaryoter
PL334769A1 (en) Derivatives of 5-aroylnaphtene
EP1012229A4 (en) REGULATORS OF UCP2 PROTEIN GENE EXPRESSION
AU2002300895A1 (en) Regulation of quinolate phosphoribosyl transferase expression
PL338777A1 (en) Derivative of piperidinylmethyloxazolydinone
GB9720533D0 (en) Regulation of gene expression
GB2326175B (en) Transition member for varying ceiling levels
GB9703672D0 (en) Inhibition of gene expression
GB9706060D0 (en) Inhibition of gene expression
GB9703663D0 (en) Inhibition of gene expression
AUPP414198A0 (en) Regulation of transgene expression
ZA985333B (en) Stabilizing of an object
GB9702211D0 (en) Inhibitors of farnesyl-protein transferase
GB9703014D0 (en) Inhibitors of farnesyl-protein transferase
GB9701589D0 (en) Inhibitors of farnesyl-protein transferase