GB942877A - Improvements in or relating to a thiaxanthene derivative - Google Patents
Improvements in or relating to a thiaxanthene derivativeInfo
- Publication number
- GB942877A GB942877A GB6404/63A GB640463A GB942877A GB 942877 A GB942877 A GB 942877A GB 6404/63 A GB6404/63 A GB 6404/63A GB 640463 A GB640463 A GB 640463A GB 942877 A GB942877 A GB 942877A
- Authority
- GB
- United Kingdom
- Prior art keywords
- thiaxanthene
- derivative
- relating
- reacting
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- MYGXGCCFTPKWIH-UHFFFAOYSA-N 4-chloro-1-methylpiperidine Chemical compound CN1CCC(Cl)CC1 MYGXGCCFTPKWIH-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 239000007818 Grignard reagent Substances 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004795 grignard reagents Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
The invention comprises the compound of formula: <FORM:0942877/C2/1> and its acid addition salts; and its preparation by reacting thiaxanthone-9 with a grignard reagent of formula: <FORM:0942877/C2/2> wherein Hal represents chlorine, bromine or iodine, and hydrolysing the resulting reaction product. Grignard starting material is prepared in an example by reacting N-methyl-4-chloropiperidine with magnesium filings in tetrahydrofuran. Specification 829,764 also is referred to.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH496560A CH387038A (en) | 1960-04-29 | 1960-04-29 | Process for the preparation of new thioxanthenol derivatives |
| CH496660A CH387039A (en) | 1960-04-29 | 1960-04-29 | Process for the preparation of new thioxanthene derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB942877A true GB942877A (en) | 1963-11-27 |
Family
ID=25696632
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6404/63A Expired GB942877A (en) | 1960-04-29 | 1961-03-27 | Improvements in or relating to a thiaxanthene derivative |
| GB11077/61A Expired GB942876A (en) | 1960-04-29 | 1961-03-27 | Improvements in or relating to piperidylidene-thiaxanthene |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB11077/61A Expired GB942876A (en) | 1960-04-29 | 1961-03-27 | Improvements in or relating to piperidylidene-thiaxanthene |
Country Status (5)
| Country | Link |
|---|---|
| CY (1) | CY374A (en) |
| FR (1) | FR1504M (en) |
| GB (2) | GB942877A (en) |
| MY (1) | MY6700086A (en) |
| NL (1) | NL121823C (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4777177A (en) * | 1984-10-19 | 1988-10-11 | Ciba-Geigy Corporation | Pesticidal thioxanthen-9-ylidenepiperidines |
| EP1655027A1 (en) * | 2004-11-04 | 2006-05-10 | Biofrontera Pharmaceuticals GmbH | 9-(N-methyl-piperidyliden-4)-thioxanthene for treatment of pulmonary hypertension and migraine |
-
1961
- 1961-03-27 GB GB6404/63A patent/GB942877A/en not_active Expired
- 1961-03-27 GB GB11077/61A patent/GB942876A/en not_active Expired
- 1961-04-19 NL NL263791A patent/NL121823C/en active
- 1961-07-26 FR FR869127A patent/FR1504M/en not_active Expired
-
1967
- 1967-03-01 CY CY37467A patent/CY374A/en unknown
- 1967-12-31 MY MY196786A patent/MY6700086A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL121823C (en) | 1967-02-15 |
| CY374A (en) | 1967-03-01 |
| MY6700086A (en) | 1967-12-31 |
| GB942876A (en) | 1963-11-27 |
| NL263791A (en) | 1964-06-10 |
| FR1504M (en) | 1962-10-01 |
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