GB860336A - N-substituted 2-phenyl-7-aminoalkoxy chromones and a process for preparing them - Google Patents
N-substituted 2-phenyl-7-aminoalkoxy chromones and a process for preparing themInfo
- Publication number
- GB860336A GB860336A GB18457/59A GB1845759A GB860336A GB 860336 A GB860336 A GB 860336A GB 18457/59 A GB18457/59 A GB 18457/59A GB 1845759 A GB1845759 A GB 1845759A GB 860336 A GB860336 A GB 860336A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenyl
- substituted
- chromones
- radicals
- aminoalkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- OMICQBVLCVRFGN-UHFFFAOYSA-N 2-(4-methoxyphenyl)-1-benzopyran-4-one Chemical group C1=CC(OC)=CC=C1C1=CC(=O)C2=CC=CC=C2O1 OMICQBVLCVRFGN-UHFFFAOYSA-N 0.000 abstract 1
- MQGPSCMMNJKMHQ-UHFFFAOYSA-N 7-hydroxyflavone Chemical compound C=1C(O)=CC=C(C(C=2)=O)C=1OC=2C1=CC=CC=C1 MQGPSCMMNJKMHQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N flavone Chemical group O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises 7-aminoalkoxy-2-phenyl chromones substituted at the nitrogen atom by two alkyl radicals which may, together with the nitrogen atom, form part of a saturated heterocyclic ring, and optionally bearing alkoxy groups in the phenyl ring and acid addition salts thereof, together with a process for their preparation by reacting an alkali metal salt of 2-phenyl-7-hydroxy chromone with a basically substituted alkyl halide in the presence of an inert organic solvent, preferably dioxane. Examples detail the preparation of 2-phenylchromones bearing in position 7 N-g -dimethyl-aminopropoxy-, b -piperidinoethoxy-, N-b -dimethylaminoethoxy-, N - b - diethylaminoethoxy- and N-b -morpholinoethoxy - radicals and of 2-(p-methoxyphenyl) chromones substituted in position 7 by the above groups (excepting the last) and also by b -pyrrolidinoethoxy- and g -pyrrolidinopropoxy-radicals.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE860336X | 1958-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB860336A true GB860336A (en) | 1961-02-01 |
Family
ID=6791463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB18457/59A Expired GB860336A (en) | 1958-05-30 | 1959-05-29 | N-substituted 2-phenyl-7-aminoalkoxy chromones and a process for preparing them |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB860336A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2137730A1 (en) * | 1971-05-14 | 1972-12-29 | Boehringer Mannheim Gmbh | |
| FR2156469A1 (en) * | 1971-10-21 | 1973-06-01 | Blaise Rolland | Tetrahydroisoquinolinoylalkoxy-7-(2-phenyl)-gamma - -benzopyrones - as spasmolytics and vascular protecting agents |
| FR2191892A1 (en) * | 1972-07-13 | 1974-02-08 | Blaise Rolland | Tetrahydroisoquinolinoylalkoxy-7-(2-phenyl)-gamma - -benzopyrones - as spasmolytics and vascular protecting agents |
-
1959
- 1959-05-29 GB GB18457/59A patent/GB860336A/en not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2137730A1 (en) * | 1971-05-14 | 1972-12-29 | Boehringer Mannheim Gmbh | |
| FR2156469A1 (en) * | 1971-10-21 | 1973-06-01 | Blaise Rolland | Tetrahydroisoquinolinoylalkoxy-7-(2-phenyl)-gamma - -benzopyrones - as spasmolytics and vascular protecting agents |
| FR2191892A1 (en) * | 1972-07-13 | 1974-02-08 | Blaise Rolland | Tetrahydroisoquinolinoylalkoxy-7-(2-phenyl)-gamma - -benzopyrones - as spasmolytics and vascular protecting agents |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2093013T3 (en) | DERIVATIVES OF ALCOXIIMINOACETAMIDA AND ITS APPLICATION AS FUNGICIDES. | |
| FR1159125A (en) | Process for preparing phenyl-thiazine derivatives having as basic substituent a heterocyclic ring containing a nitrogen atom | |
| GB852795A (en) | Substituted furyl-thiadiazoles and a process for their production | |
| GB860336A (en) | N-substituted 2-phenyl-7-aminoalkoxy chromones and a process for preparing them | |
| FR2364922A1 (en) | SOLID SALT OF CEPHALOSPORIN AND METHOD FOR PREPARING IT | |
| SE7608306L (en) | NEW 5-FLUOROPYRIMIDIN-4-ON DERIVATIVES | |
| ES332645A1 (en) | Procedure for the preparation of new N-heterocicles. (Machine-translation by Google Translate, not legally binding) | |
| ES307984A1 (en) | Procedure for the preparation of new amidas of ariloxyacetic acid. (Machine-translation by Google Translate, not legally binding) | |
| GB901312A (en) | Pyridylcarbamyl lower alkane derivatives and processes for preparing them | |
| ES404601A1 (en) | A PROCEDURE FOR THE PRODUCTION OF PENICILLIN-NA ESTERS OR PENICILLIN SULFOXIDE. | |
| GB1079224A (en) | Process for the production of pyridazinone derivatives | |
| GB810917A (en) | Salts of oestrone sulphate and the manufacture thereof | |
| YU39078B (en) | Process for obtaining 1-thiadiazolyl-5-acylimidazolidinones | |
| GB1022040A (en) | Process for the preparation of sulphonyl carbodiimides and of n-sulphonyl ureas | |
| GB1061766A (en) | A process for preparing 2-alkoxycycloheptimidazole derivatives | |
| GB878603A (en) | Salicyclic acid derivatives | |
| GB1323020A (en) | Process for the preparation of 1-substituted 4-amino-3-pyrrolin- 2-ones | |
| ES336289A1 (en) | Procedure for preparing fluoracilaminotriclorometilmetano derivatives of insecticides and acaricides effects. (Machine-translation by Google Translate, not legally binding) | |
| GB1113783A (en) | Improvements in or relating to esters of 4-alkyl-2,6-dinitrophenols and pesticides containing them | |
| ES398973A1 (en) | PROCEDURE FOR OBTAINING A DERIVATIVE OF RIFAMICI-NA SV. | |
| GB869807A (en) | Process for the preparation of 3-substituted oxazolid-2:4-diones | |
| ES219534A1 (en) | A PROCEDURE FOR OBTAINING NEW DERIVATIVES OF 7-9-PIRIMIDO-PIRIMIDINA- (1,3) | |
| ES237579A1 (en) | PROCEDURE FOR THE MANUFACTURE OF NEW DERIVATIVES OF SULFANILAMIDO-ISOXAZOLE | |
| ES407902A1 (en) | Procedure for the obtaining of i- (m-trifluoromethyl-phenyl) -3-alkylaminoalcaxi-indazoles and its adhesive salts. (Machine-translation by Google Translate, not legally binding) | |
| ES229834A1 (en) | Procedure for the preparation of a 1-azafenotiazine (Machine-translation by Google Translate, not legally binding) |