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GB1383647A - Process for the manufacture of benzodiazepine derivatives - Google Patents

Process for the manufacture of benzodiazepine derivatives

Info

Publication number
GB1383647A
GB1383647A GB3210771A GB3210771A GB1383647A GB 1383647 A GB1383647 A GB 1383647A GB 3210771 A GB3210771 A GB 3210771A GB 3210771 A GB3210771 A GB 3210771A GB 1383647 A GB1383647 A GB 1383647A
Authority
GB
United Kingdom
Prior art keywords
manufacture
july
benzodiazepine derivatives
formula
comptroller
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3210771A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Products Ltd
Original Assignee
Roche Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE785962D priority Critical patent/BE785962A/xx
Priority to BE785963D priority patent/BE785963A/xx
Application filed by Roche Products Ltd filed Critical Roche Products Ltd
Priority to GB3210771A priority patent/GB1383647A/en
Priority to CH859572A priority patent/CH569007A5/xx
Priority to CH932972A priority patent/CH570388A5/xx
Priority to PH13685A priority patent/PH10943A/en
Priority to IE927/72A priority patent/IE36885B1/xx
Priority to IE926/72A priority patent/IE36734B1/xx
Priority to ZA724577A priority patent/ZA724577B/xx
Priority to FR7224437A priority patent/FR2144830A1/fr
Priority to IL39847A priority patent/IL39847A/xx
Priority to CA146,477A priority patent/CA963903A/en
Priority to YU01769/72A priority patent/YU176972A/xx
Priority to ZA724639A priority patent/ZA724639B/xx
Priority to IL39844A priority patent/IL39844A/xx
Priority to YU01770/72A priority patent/YU177072A/xx
Priority to AU44362/72A priority patent/AU463475B2/en
Priority to HUHO1496A priority patent/HU166414B/hu
Priority to SE7209050A priority patent/SE416807B/xx
Priority to AT584672A priority patent/AT334376B/de
Priority to AT584472A priority patent/AT327198B/de
Priority to DE19722233483 priority patent/DE2233483C3/de
Priority to ES404627A priority patent/ES404627A1/es
Priority to DK341372A priority patent/DK147482C/da
Priority to FI1932/72A priority patent/FI57258C/fi
Priority to NO2454/72A priority patent/NO132320C/no
Priority to AU44361/72A priority patent/AU458347B2/en
Priority to HUHO1497A priority patent/HU168636B/hu
Priority to NL7209490.A priority patent/NL164282C/xx
Priority to ES404626A priority patent/ES404626A1/es
Priority to AR242957A priority patent/AR192656A1/es
Priority to SE7209051A priority patent/SE416651B/xx
Priority to DE2233482A priority patent/DE2233482A1/de
Priority to FR7224668A priority patent/FR2144868B1/fr
Priority to NO02453/72*[A priority patent/NO130189B/no
Priority to AR242956A priority patent/AR192655A1/es
Priority to NL7209489.A priority patent/NL167426C/xx
Priority to JP6811472A priority patent/JPS5331878B1/ja
Publication of GB1383647A publication Critical patent/GB1383647A/en
Priority to KE286178A priority patent/KE2861A/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Sealing Material Composition (AREA)
  • Paints Or Removers (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
GB3210771A 1971-07-08 1971-07-08 Process for the manufacture of benzodiazepine derivatives Expired GB1383647A (en)

Priority Applications (39)

Application Number Priority Date Filing Date Title
BE785962D BE785962A (fr) 1971-07-08 Procede pour la preparation de derives de benzodiazepine
BE785963D BE785963A (fr) 1971-07-08 Procede pour la preparation de derives de benzodiazepine
GB3210771A GB1383647A (en) 1971-07-08 1971-07-08 Process for the manufacture of benzodiazepine derivatives
CH859572A CH569007A5 (es) 1971-07-08 1972-06-09
CH932972A CH570388A5 (es) 1971-07-08 1972-06-21
IE926/72A IE36734B1 (en) 1971-07-08 1972-07-03 A process for the manufacture of benzodiazepine derivatives
IE927/72A IE36885B1 (en) 1971-07-08 1972-07-03 A process for the manufacture of benzodiazepine derivatives
PH13685A PH10943A (en) 1971-07-08 1972-07-03 An improved process for the manufacture of benzodiazepine derivatives
ZA724577A ZA724577B (en) 1971-07-08 1972-07-04 Process for the manufacture of benzodiazepine derivatives
FR7224437A FR2144830A1 (en) 1971-07-08 1972-07-06 1,3-dihydro-5-(2-pyridyl)-2h-1,4-benzodiazepine-2-ones prodn
IL39847A IL39847A (en) 1971-07-08 1972-07-06 Process for the manufacture of 1,3-dihydro-1-methyl-5-phenyl-(or substituted phenyl)-2h-1,4-benzodiazepin 2-one derivatives
CA146,477A CA963903A (en) 1971-07-08 1972-07-06 Process for the manufacture of benzodiazepine derivatives
YU01769/72A YU176972A (en) 1971-07-08 1972-07-06 Process for obtaining benzodiazepine derivatives
ZA724639A ZA724639B (en) 1971-07-08 1972-07-06 Process for the manufacture of benzodiazepine derivatives
IL39844A IL39844A (en) 1971-07-08 1972-07-06 Process for the manufacture of 1,3-dihydro-5-(2-pyridyl)-2h-1,4-benzodiazepin-2-one derivatives
YU01770/72A YU177072A (en) 1971-07-08 1972-07-06 Process for preparing benzodiazepine derivatives
AT584672A AT334376B (de) 1971-07-08 1972-07-07 Verfahren zur herstellung von benzodiazepin-derivaten
ES404626A ES404626A1 (es) 1971-07-08 1972-07-07 Un procedimiento para la preparacion de derivados de benzo-diacepina.
SE7209050A SE416807B (sv) 1971-07-08 1972-07-07 Sett att framstella 1,4-bensodiazepinderivat
AU44362/72A AU463475B2 (en) 1971-07-08 1972-07-07 Process forthe manufacture of benzodiazepine derivatives
AT584472A AT327198B (de) 1971-07-08 1972-07-07 Verfahren zur herstellung von benzodiazepinderivaten
DE19722233483 DE2233483C3 (de) 1971-07-08 1972-07-07 Verfahren zur Herstellung von 7-Brom-l,3-dihydro-5-<2-pvridyl)-2H-l,4benzodiazepin-2-on
ES404627A ES404627A1 (es) 1971-07-08 1972-07-07 Un procedimiento para la preparacion de derivados de benzo-diacepina.
DK341372A DK147482C (da) 1971-07-08 1972-07-07 Fremgangsmaade til fremstilling af benzodiazepinderivater
FI1932/72A FI57258C (fi) 1971-07-08 1972-07-07 Foerfarande foer framstaellning av 1,3-dihydro-5-pyridyl-2h-1,4-bensodiazepin-derivat
NO2454/72A NO132320C (es) 1971-07-08 1972-07-07
AU44361/72A AU458347B2 (en) 1971-07-08 1972-07-07 Process forthe manufacture of benzodiazepine derivatives
HUHO1497A HU168636B (es) 1971-07-08 1972-07-07
NL7209490.A NL164282C (nl) 1971-07-08 1972-07-07 Werkwijze voor de bereiding van benzodiazepine- derivaten.
HUHO1496A HU166414B (es) 1971-07-08 1972-07-07
AR242957A AR192656A1 (es) 1971-07-08 1972-07-07 Procedimiento para la preparacion de derivados de benzodiacepina
SE7209051A SE416651B (sv) 1971-07-08 1972-07-07 Sett att framstella 1,4-bensodiazepinderivat
DE2233482A DE2233482A1 (de) 1971-07-08 1972-07-07 Verfahren zur herstellung von benzodiazepin-derivaten
FR7224668A FR2144868B1 (es) 1971-07-08 1972-07-07
NO02453/72*[A NO130189B (es) 1971-07-08 1972-07-07
AR242956A AR192655A1 (es) 1971-07-08 1972-07-07 Procedimiento para la preparacion de derivados de benzodiacepina
NL7209489.A NL167426C (nl) 1971-07-08 1972-07-07 Werkwijze voor de bereiding van benzodiazepinederivaten.
JP6811472A JPS5331878B1 (es) 1971-07-08 1972-07-07
KE286178A KE2861A (en) 1971-07-08 1978-07-22 A process for the manufacture of benzodiazepine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3210771A GB1383647A (en) 1971-07-08 1971-07-08 Process for the manufacture of benzodiazepine derivatives

Publications (1)

Publication Number Publication Date
GB1383647A true GB1383647A (en) 1974-02-12

Family

ID=10333351

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3210771A Expired GB1383647A (en) 1971-07-08 1971-07-08 Process for the manufacture of benzodiazepine derivatives

Country Status (18)

Country Link
AR (1) AR192655A1 (es)
AT (1) AT334376B (es)
AU (1) AU463475B2 (es)
BE (1) BE785962A (es)
CA (1) CA963903A (es)
CH (1) CH570388A5 (es)
DE (1) DE2233482A1 (es)
ES (1) ES404627A1 (es)
FR (1) FR2144868B1 (es)
GB (1) GB1383647A (es)
HU (1) HU168636B (es)
IE (1) IE36885B1 (es)
IL (1) IL39847A (es)
NL (1) NL167426C (es)
NO (1) NO130189B (es)
PH (1) PH10943A (es)
YU (1) YU176972A (es)
ZA (2) ZA724577B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH578544A5 (es) * 1972-08-21 1976-08-13 Hoffmann La Roche
JPS52106881A (en) * 1976-03-05 1977-09-07 Crc Ricerca Chim Production of 1*44 benzodiazepine derivative
FR2364207A1 (fr) * 1976-09-09 1978-04-07 Scherico Ltd Procede ameliore pour la preparation de 1,4-benzodiazepines
CN103804310A (zh) * 2013-11-19 2014-05-21 华中药业股份有限公司 一种制备高纯度7-氯-5-苯基-苯并二氮杂卓-2-酮的方法

Also Published As

Publication number Publication date
IL39847A0 (en) 1972-09-28
DE2233482A1 (de) 1973-01-25
CH570388A5 (es) 1975-12-15
PH10943A (en) 1977-10-05
HU168636B (es) 1976-06-28
IE36885L (en) 1973-01-08
CA963903A (en) 1975-03-04
NL167426B (nl) 1981-07-16
AT334376B (de) 1976-01-10
NL167426C (nl) 1981-12-16
ZA724639B (en) 1973-03-28
AU4436272A (en) 1974-01-10
YU176972A (en) 1979-07-10
FR2144868A1 (es) 1973-02-16
BE785962A (fr) 1973-01-08
NO130189B (es) 1974-07-22
FR2144868B1 (es) 1976-05-14
IL39847A (en) 1976-05-31
ZA724577B (en) 1973-03-28
IE36885B1 (en) 1977-03-16
ES404627A1 (es) 1975-06-16
ATA584672A (de) 1976-05-15
NL7209489A (es) 1973-01-10
AU463475B2 (en) 1975-07-31
AR192655A1 (es) 1973-02-28

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years