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FI972366A7 - Lipopolyaminer som transfekterande ämnen och deras farmaceutisk använd ning - Google Patents

Lipopolyaminer som transfekterande ämnen och deras farmaceutisk använd ning Download PDF

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Publication number
FI972366A7
FI972366A7 FI972366A FI972366A FI972366A7 FI 972366 A7 FI972366 A7 FI 972366A7 FI 972366 A FI972366 A FI 972366A FI 972366 A FI972366 A FI 972366A FI 972366 A7 FI972366 A7 FI 972366A7
Authority
FI
Finland
Prior art keywords
lipopolyamines
pharmaceutical use
transfecting agents
transfecting
agents
Prior art date
Application number
FI972366A
Other languages
English (en)
Finnish (fi)
Other versions
FI972366L (sv
FI972366A0 (sv
Inventor
Daniel Scherman
Gerardo Byk
Catherine Dubertret
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of FI972366L publication Critical patent/FI972366L/sv
Publication of FI972366A0 publication Critical patent/FI972366A0/sv
Publication of FI972366A7 publication Critical patent/FI972366A7/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
FI972366A 1994-12-05 1995-12-04 Lipopolyaminer som transfekterande ämnen och deras farmaceutisk använd ning FI972366A7 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9414596A FR2727679B1 (fr) 1994-12-05 1994-12-05 Nouveaux agents de transfection et leurs applications pharmaceutiques
PCT/FR1995/001595 WO1996017823A1 (fr) 1994-12-05 1995-12-04 Lipopolyamines comme agents de transfection et leurs applications pharmaceutiques

Publications (3)

Publication Number Publication Date
FI972366L FI972366L (sv) 1997-06-04
FI972366A0 FI972366A0 (sv) 1997-06-04
FI972366A7 true FI972366A7 (sv) 1997-06-04

Family

ID=9469480

Family Applications (1)

Application Number Title Priority Date Filing Date
FI972366A FI972366A7 (sv) 1994-12-05 1995-12-04 Lipopolyaminer som transfekterande ämnen och deras farmaceutisk använd ning

Country Status (22)

Country Link
US (1) US6107286A (sv)
EP (1) EP0796240B1 (sv)
JP (1) JPH10509958A (sv)
KR (1) KR100447517B1 (sv)
AT (1) ATE200662T1 (sv)
AU (1) AU713662B2 (sv)
BR (1) BR9510080A (sv)
CA (1) CA2208184A1 (sv)
CZ (1) CZ289513B6 (sv)
DE (1) DE69520748T2 (sv)
DK (1) DK0796240T3 (sv)
ES (1) ES2157351T3 (sv)
FI (1) FI972366A7 (sv)
FR (1) FR2727679B1 (sv)
GR (1) GR3035759T3 (sv)
HU (1) HUT77171A (sv)
IL (1) IL116251A (sv)
NO (1) NO972566L (sv)
PT (1) PT796240E (sv)
SK (1) SK282601B6 (sv)
WO (1) WO1996017823A1 (sv)
ZA (1) ZA9510326B (sv)

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* Cited by examiner, † Cited by third party
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EP0796240A1 (fr) 1997-09-24
FR2727679B1 (fr) 1997-01-03
DK0796240T3 (da) 2001-05-07
AU4307296A (en) 1996-06-26
CZ289513B6 (cs) 2002-02-13
JPH10509958A (ja) 1998-09-29
GR3035759T3 (en) 2001-07-31
KR100447517B1 (ko) 2004-11-20
EP0796240B1 (fr) 2001-04-18
CZ171197A3 (cs) 1998-03-18
WO1996017823A1 (fr) 1996-06-13
FI972366L (sv) 1997-06-04
IL116251A0 (en) 1996-03-31
FR2727679A1 (fr) 1996-06-07
SK282601B6 (sk) 2002-10-08
DE69520748T2 (de) 2001-09-13
HUT77171A (hu) 1998-03-02
PT796240E (pt) 2001-09-28
BR9510080A (pt) 1997-12-30
FI972366A0 (sv) 1997-06-04
CA2208184A1 (fr) 1996-06-13
ES2157351T3 (es) 2001-08-16
DE69520748D1 (de) 2001-05-23
ZA9510326B (en) 1996-06-11
AU713662B2 (en) 1999-12-09
US6107286A (en) 2000-08-22
IL116251A (en) 2000-11-21

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