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FI964936L - Bensopyraner och deras användning som terapeutiska medel - Google Patents

Bensopyraner och deras användning som terapeutiska medel Download PDF

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Publication number
FI964936L
FI964936L FI964936A FI964936A FI964936L FI 964936 L FI964936 L FI 964936L FI 964936 A FI964936 A FI 964936A FI 964936 A FI964936 A FI 964936A FI 964936 L FI964936 L FI 964936L
Authority
FI
Finland
Prior art keywords
benzopyrans
therapeutic agents
therapeutic
agents
Prior art date
Application number
FI964936A
Other languages
English (en)
Finnish (fi)
Other versions
FI964936A0 (sv
FI120686B (sv
Inventor
Wai Ngor Chan
Helen Kate Ann Morgan
Mervyn Thompson
John Morris Evans
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9411632A external-priority patent/GB9411632D0/en
Priority claimed from GB9411798A external-priority patent/GB9411798D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of FI964936A0 publication Critical patent/FI964936A0/sv
Publication of FI964936L publication Critical patent/FI964936L/sv
Application granted granted Critical
Publication of FI120686B publication Critical patent/FI120686B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
FI964936A 1994-06-10 1996-12-10 Bensopyraner och deras användning som terapeutiska medel FI120686B (sv)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB9411632A GB9411632D0 (en) 1994-06-10 1994-06-10 Novel treatment
GB9411632 1994-06-10
GB9411798A GB9411798D0 (en) 1994-06-13 1994-06-13 Novel treatment
GB9411798 1994-06-13
EP9502076 1995-05-31
PCT/EP1995/002076 WO1995034545A1 (en) 1994-06-10 1995-05-31 Benzopyrans and their use as therapeutic agents

Publications (3)

Publication Number Publication Date
FI964936A0 FI964936A0 (sv) 1996-12-10
FI964936L true FI964936L (sv) 1997-02-06
FI120686B FI120686B (sv) 2010-01-29

Family

ID=26305044

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964936A FI120686B (sv) 1994-06-10 1996-12-10 Bensopyraner och deras användning som terapeutiska medel

Country Status (29)

Country Link
US (1) US5760074A (sv)
EP (2) EP1114821B1 (sv)
JP (2) JP3575767B2 (sv)
KR (1) KR100397721B1 (sv)
CN (2) CN1234702C (sv)
AP (1) AP714A (sv)
AT (2) ATE250052T1 (sv)
AU (1) AU701060B2 (sv)
BG (1) BG63339B1 (sv)
BR (1) BR9507980A (sv)
CA (1) CA2192480C (sv)
CY (1) CY2508B1 (sv)
CZ (1) CZ286081B6 (sv)
DE (2) DE69524871T2 (sv)
DK (2) DK0764157T3 (sv)
ES (2) ES2170798T3 (sv)
FI (1) FI120686B (sv)
HK (1) HK1039115B (sv)
HU (1) HUT76136A (sv)
NO (1) NO315651B1 (sv)
NZ (1) NZ287872A (sv)
OA (1) OA10593A (sv)
PL (1) PL188134B1 (sv)
PT (2) PT1114821E (sv)
RO (1) RO113463B1 (sv)
SG (1) SG67930A1 (sv)
SI (2) SI0764157T1 (sv)
SK (1) SK281456B6 (sv)
WO (1) WO1995034545A1 (sv)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010021780A1 (en) * 1992-12-11 2001-09-13 Smithkline Beecham P.L.C. Pharmaceutical composition containing bicyclic type compounds
GB9411635D0 (en) * 1994-06-10 1994-08-03 Smithkline Beecham Plc Novel treatment
US6492415B2 (en) * 1996-09-18 2002-12-10 Smithkline Beecham P.L.C. Use of benzopyranols to treat neurological disorders
GB9619492D0 (en) * 1996-09-18 1996-10-30 Smithkline Beecham Plc Novel treatment
GB9726543D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel compositions
GB9813949D0 (en) * 1998-06-29 1998-08-26 Smithkline Beecham Plc Novel compounds
GB0028697D0 (en) * 2000-11-23 2001-01-10 S P A Novel process
KR20070118103A (ko) * 2005-04-04 2007-12-13 다케다 야쿠힌 고교 가부시키가이샤 우울증 또는 불안신경증의 예방 또는 치료제
WO2009147441A2 (en) * 2008-06-05 2009-12-10 Minster Research Limited Novel treatments
CA2726878A1 (en) * 2008-06-05 2009-12-10 Minster Research Limited Novel treatments
CN102770134A (zh) 2009-12-03 2012-11-07 普罗克西梅根有限公司 传染性失调的治疗
EP2506846A1 (en) * 2009-12-03 2012-10-10 Proximagen Limited Treatment of allodynia and hyperalgesia
WO2014006407A1 (en) 2012-07-03 2014-01-09 Proximagen Limited Pro-drug compounds
GB201304814D0 (en) * 2013-03-15 2013-05-01 Proximagen Ltd Pro-drug compounds
GB201322932D0 (en) * 2013-12-23 2014-02-12 Proximagen Ltd Pro-drug compounds
GB201322934D0 (en) 2013-12-23 2014-02-12 Proximagen Ltd Prodrug compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3479726D1 (de) * 1983-05-18 1989-10-19 Beecham Group Plc Benzopyran derivatives.
GB9112721D0 (en) * 1991-06-13 1991-07-31 Smithkline Beecham Plc Novel treatment
SG49907A1 (en) * 1992-12-11 1998-06-15 Smithkline Beecham Corp Pharmaceutical composition containing bicyclic type compounds
AU679475B2 (en) * 1992-12-11 1997-07-03 Smithkline Beecham Corporation Bicyclic compounds with pharmaceutical activity
US5536718A (en) * 1995-01-17 1996-07-16 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists

Also Published As

Publication number Publication date
RO113463B1 (ro) 1998-07-30
CN1234702C (zh) 2006-01-04
SK281456B6 (sk) 2001-03-12
JP3575767B2 (ja) 2004-10-13
CZ361796A3 (en) 1997-08-13
SG67930A1 (en) 1999-10-19
HU9603415D0 (en) 1997-02-28
BR9507980A (pt) 1997-08-12
DE69524871D1 (de) 2002-02-07
ES2207590T3 (es) 2004-06-01
AP714A (en) 1998-12-23
ATE250052T1 (de) 2003-10-15
CN1174975C (zh) 2004-11-10
BG101040A (en) 1997-08-29
FI964936A0 (sv) 1996-12-10
HK1039115B (en) 2004-08-13
DK1114821T3 (da) 2004-02-02
AP9600889A0 (en) 1997-01-31
JP2003238554A (ja) 2003-08-27
PL317579A1 (en) 1997-04-14
OA10593A (en) 2002-07-10
CA2192480C (en) 2007-07-24
US5760074A (en) 1998-06-02
ES2170798T3 (es) 2002-08-16
ATE211469T1 (de) 2002-01-15
EP0764157B1 (en) 2002-01-02
PT1114821E (pt) 2004-02-27
NZ287872A (en) 1998-05-27
PT764157E (pt) 2002-06-28
CY2508B1 (en) 2005-12-23
KR100397721B1 (ko) 2004-04-28
HK1001286A1 (en) 1998-06-12
SI0764157T1 (en) 2002-06-30
SK158796A3 (en) 1997-07-09
DK0764157T3 (da) 2002-04-22
NO315651B1 (no) 2003-10-06
PL188134B1 (pl) 2004-12-31
WO1995034545A1 (en) 1995-12-21
BG63339B1 (bg) 2001-10-31
EP1114821A1 (en) 2001-07-11
HK1039115A1 (en) 2002-04-12
SI1114821T1 (en) 2004-02-29
NO965260D0 (no) 1996-12-09
CN1154698A (zh) 1997-07-16
DE69524871T2 (de) 2002-08-22
HUT76136A (en) 1997-06-30
DE69531801T2 (de) 2004-07-01
CA2192480A1 (en) 1995-12-21
AU701060B2 (en) 1999-01-21
FI120686B (sv) 2010-01-29
JPH10501251A (ja) 1998-02-03
CZ286081B6 (cs) 2000-01-12
DE69531801D1 (de) 2003-10-23
NO965260L (no) 1997-02-06
EP1114821B1 (en) 2003-09-17
AU2672795A (en) 1996-01-05
CN1336369A (zh) 2002-02-20
EP0764157A1 (en) 1997-03-26

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