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FI971536L - Keratinosyytti-kasvutekijän analogeja - Google Patents

Keratinosyytti-kasvutekijän analogeja Download PDF

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Publication number
FI971536L
FI971536L FI971536A FI971536A FI971536L FI 971536 L FI971536 L FI 971536L FI 971536 A FI971536 A FI 971536A FI 971536 A FI971536 A FI 971536A FI 971536 L FI971536 L FI 971536L
Authority
FI
Finland
Prior art keywords
growth factor
keratinocyte growth
factor analogs
analogs
keratinocyte
Prior art date
Application number
FI971536A
Other languages
English (en)
Swedish (sv)
Other versions
FI120040B (fi
FI971536A0 (fi
Inventor
Charles F Morris
William C Kenney
Bao-Lu Chen
Eric W Hsu
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of FI971536A0 publication Critical patent/FI971536A0/fi
Publication of FI971536L publication Critical patent/FI971536L/fi
Application granted granted Critical
Publication of FI120040B publication Critical patent/FI120040B/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1825Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FI971536A 1994-10-13 1997-04-11 Keratinosyytti-kasvutekijän analogeja FI120040B (fi)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US32347594A 1994-10-13 1994-10-13
US32334094A 1994-10-13 1994-10-13
US32347594 1994-10-13
US32334094 1994-10-13
US48782595A 1995-06-07 1995-06-07
US48782595 1995-06-07
IB9500992 1995-10-12
PCT/IB1995/000992 WO1996011950A1 (en) 1994-10-13 1995-10-12 Method of treating diabetes mellitus using kgf

Publications (3)

Publication Number Publication Date
FI971536A0 FI971536A0 (fi) 1997-04-11
FI971536L true FI971536L (fi) 1997-06-09
FI120040B FI120040B (fi) 2009-06-15

Family

ID=27406268

Family Applications (2)

Application Number Title Priority Date Filing Date
FI971420A FI971420A0 (fi) 1994-10-13 1995-10-12 Menetelmä diabetes mellituksen hoitamiseksi KGF:ää käyttämällä
FI971536A FI120040B (fi) 1994-10-13 1997-04-11 Keratinosyytti-kasvutekijän analogeja

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI971420A FI971420A0 (fi) 1994-10-13 1995-10-12 Menetelmä diabetes mellituksen hoitamiseksi KGF:ää käyttämällä

Country Status (23)

Country Link
EP (2) EP0785948B1 (fi)
JP (2) JP4426646B2 (fi)
KR (1) KR100278597B1 (fi)
CN (1) CN1168678A (fi)
AT (2) ATE237633T1 (fi)
AU (1) AU3707795A (fi)
BG (2) BG101392A (fi)
BR (2) BR9509269A (fi)
CA (2) CA2201940C (fi)
CZ (3) CZ98197A3 (fi)
DE (2) DE69530403T2 (fi)
DK (2) DK0804479T3 (fi)
EE (2) EE03975B1 (fi)
ES (2) ES2196082T3 (fi)
FI (2) FI971420A0 (fi)
HU (2) HU226168B1 (fi)
NO (2) NO971566L (fi)
NZ (2) NZ505502A (fi)
PL (2) PL320484A1 (fi)
PT (2) PT785948E (fi)
SI (2) SI0804479T1 (fi)
SK (2) SK43197A3 (fi)
WO (2) WO1996011950A1 (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2153816T3 (es) 1989-01-31 2001-03-16 Jeffrey S Rubin Adn que codifica un factor de crecimiento especifico contra celulas epiteliales.
US7084119B2 (en) 1993-06-29 2006-08-01 Chiron Corporation Truncated keratinocyte growth factor (KGF) having increased biological activity
EP1493812A3 (en) 1993-06-29 2006-02-08 Chiron Corporation A truncated keratinocyte growth factor (KGF) having increased biological activity
PT785949E (pt) * 1994-10-13 2003-09-30 Amgen Inc Metodo para purificar factores de crescimento de queratinocitos
US7232667B2 (en) 1995-02-14 2007-06-19 Human Genome Sciences, Inc. Keratinocyte growth factor-2 polynucleotides
US6077692A (en) * 1995-02-14 2000-06-20 Human Genome Sciences, Inc. Keratinocyte growth factor-2
US6693077B1 (en) 1995-02-14 2004-02-17 Human Genome Sciences, Inc. Keratinocyte growth factor-2
DE69603269T3 (de) * 1995-04-27 2007-02-22 Coöperatie Cosun U.A. Derivate von inulin
SI0935652T1 (en) * 1996-10-15 2004-06-30 Amgen Inc. Keratinocyte growth factor-2 products
ATE263239T1 (de) * 1996-10-15 2004-04-15 Amgen Inc Produkte des keratinocyten-wachstumsfaktors 2 (kgf-2)
US6743422B1 (en) 1996-10-15 2004-06-01 Amgen, Inc. Keratinocyte growth factor-2 products
US7495087B2 (en) 1997-07-14 2009-02-24 Bolder Biotechnology, Inc. Cysteine muteins in the C-D loop of human interleukin-11
US7153943B2 (en) 1997-07-14 2006-12-26 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins, and methods of use thereof
DE69838552T2 (de) 1997-07-14 2008-05-21 Bolder Biotechnology, Inc., Louisville Derivate des wachstumshormons und verwandte proteine
US20080076706A1 (en) 1997-07-14 2008-03-27 Bolder Biotechnology, Inc. Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
US6869927B1 (en) 1997-12-22 2005-03-22 Human Genome Sciences, Inc. Keratinocyte growth factor-2 formulations
KR20010033484A (ko) 1997-12-22 2001-04-25 휴먼 게놈 사이언시즈, 인크. 각질세포 성장 인자-2 제제
US6242666B1 (en) * 1998-12-16 2001-06-05 The Scripps Research Institute Animal model for identifying a common stem/progenitor to liver cells and pancreatic cells
US8288126B2 (en) 1999-01-14 2012-10-16 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
EP1144613B2 (en) * 1999-01-14 2020-05-06 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
US6248725B1 (en) 1999-02-23 2001-06-19 Amgen, Inc. Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction
JP2004526437A (ja) * 2001-02-06 2004-09-02 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 低減された免疫原性を有する修飾されたケラチノサイト成長因子(kgf)
PL374269A1 (en) * 2001-08-21 2005-10-03 Chiron Corporation Kgf polypeptide compositions
AU2007214362B2 (en) * 2001-08-21 2009-11-26 Novartis Vaccines And Diagnostics, Inc. KGF polypeptide compositions
CA2589889C (en) 2004-12-15 2013-07-30 Amgen Inc. Therapeutic formulations of keratinocyte growth factor
CN102242124B (zh) * 2010-05-10 2013-05-22 齐鲁制药有限公司 改造的角化细胞生长因子基因及其在酵母中的表达
KR102440312B1 (ko) * 2020-08-28 2022-09-05 한국해양과학기술원 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959314A (en) * 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
JPH01137994A (ja) * 1987-08-10 1989-05-30 Shionogi & Co Ltd reg蛋白質
WO1990000877A1 (en) * 1988-07-27 1990-02-08 Marjan International Pty Ltd Carpet stretcher
ES2153816T3 (es) * 1989-01-31 2001-03-16 Jeffrey S Rubin Adn que codifica un factor de crecimiento especifico contra celulas epiteliales.
JP3303211B2 (ja) * 1991-04-26 2002-07-15 武田薬品工業株式会社 bFGFムテインおよびその製造法
HU220641B1 (hu) * 1993-03-26 2002-03-28 Amgen Inc. Keratinocita növekedési faktor alkalmazása
US5348563A (en) * 1993-06-29 1994-09-20 Honeywell Inc. Air purifying apparatus
EP1493812A3 (en) * 1993-06-29 2006-02-08 Chiron Corporation A truncated keratinocyte growth factor (KGF) having increased biological activity
GB9315501D0 (en) * 1993-07-27 1993-09-08 Ici Plc Surfactant compositions
AU7475694A (en) * 1993-08-02 1995-02-28 Prizm Pharmaceuticals, Inc. Monogenous preparations of cytotoxic conjugates

Also Published As

Publication number Publication date
HU226168B1 (en) 2008-05-28
EP0804479A1 (en) 1997-11-05
NO971568L (no) 1997-06-12
CA2201940A1 (en) 1996-04-25
PL182888B1 (pl) 2002-03-29
CZ98197A3 (cs) 1998-11-11
FI971420A7 (fi) 1997-04-04
FI971420L (fi) 1997-04-04
NZ505502A (en) 2005-01-28
CZ105097A3 (cs) 1998-10-14
DK0785948T3 (da) 2003-08-04
JP4426646B2 (ja) 2010-03-03
ATE237633T1 (de) 2003-05-15
BG63167B1 (bg) 2001-05-31
DE69535264T2 (de) 2007-02-01
BG101392A (en) 1997-10-31
AU3708395A (en) 1996-05-06
SK45597A3 (en) 1999-02-11
EE9700225A (et) 1998-02-16
CA2202075A1 (en) 1996-04-25
CZ297328B6 (cs) 2006-11-15
SI0785948T1 (en) 2003-08-31
PT804479E (pt) 2007-02-28
WO1996011949A2 (en) 1996-04-25
BG101408A (bg) 1997-12-30
EP0785948A1 (en) 1997-07-30
BR9509329A (pt) 1997-10-14
CN1168678A (zh) 1997-12-24
ES2196082T3 (es) 2003-12-16
SK43197A3 (en) 1999-03-12
NO971566L (no) 1997-04-14
ES2273338T3 (es) 2007-05-01
CA2201940C (en) 2009-05-12
NO318761B1 (no) 2005-05-02
WO1996011950A1 (en) 1996-04-25
SI0804479T1 (sl) 2006-12-31
EP0785948B1 (en) 2003-04-16
DE69530403D1 (de) 2003-05-22
FI120040B (fi) 2009-06-15
KR100278597B1 (ko) 2001-01-15
EP0804479B1 (en) 2006-10-11
PL319784A1 (en) 1997-08-18
NZ335109A (en) 2000-08-25
NO971568D0 (no) 1997-04-04
CZ297329B6 (cs) 2006-11-15
EE9700081A (et) 1997-10-15
NO971566D0 (no) 1997-04-04
JP4216329B2 (ja) 2009-01-28
SK284534B6 (sk) 2005-06-02
DE69535264D1 (de) 2006-11-23
CA2202075C (en) 2003-12-09
DK0804479T3 (da) 2007-01-29
JPH10507080A (ja) 1998-07-14
EE03975B1 (et) 2003-02-17
AU3707795A (en) 1996-05-06
WO1996011949A3 (en) 1996-12-12
PL320484A1 (en) 1997-09-29
FI971536A0 (fi) 1997-04-11
ATE342278T1 (de) 2006-11-15
HUT78050A (hu) 1999-07-28
AU681546B2 (en) 1997-08-28
DE69530403T2 (de) 2003-10-30
FI971420A0 (fi) 1997-04-04
PT785948E (pt) 2003-09-30
JPH10507193A (ja) 1998-07-14
BR9509269A (pt) 1997-12-23
HUT78058A (hu) 1999-07-28

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