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FI953841L - Substituoituja kinoliinijohdannaisia, menetelmä niiden valmistamseksi - Google Patents

Substituoituja kinoliinijohdannaisia, menetelmä niiden valmistamseksi Download PDF

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Publication number
FI953841L
FI953841L FI953841A FI953841A FI953841L FI 953841 L FI953841 L FI 953841L FI 953841 A FI953841 A FI 953841A FI 953841 A FI953841 A FI 953841A FI 953841 L FI953841 L FI 953841L
Authority
FI
Finland
Prior art keywords
preparation
quinoline derivatives
substituted quinoline
substituted
derivatives
Prior art date
Application number
FI953841A
Other languages
English (en)
Swedish (sv)
Other versions
FI953841A0 (fi
FI953841A7 (fi
Inventor
Reinhard Kirch
Joerg-Peter Kleim
Guenter Riess
Manfred Roesner
Irvin Winkler
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI953841A0 publication Critical patent/FI953841A0/fi
Publication of FI953841A7 publication Critical patent/FI953841A7/fi
Publication of FI953841L publication Critical patent/FI953841L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/24Oxygen atoms attached in position 8
    • C07D215/26Alcohols; Ethers thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20Spiro-condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
FI953841A 1994-08-16 1995-08-14 Substituoituja kinoliinijohdannaisia, menetelmä niiden valmistamseksi FI953841L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4428932A DE4428932A1 (de) 1994-08-16 1994-08-16 Substituierte-Chinolinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung

Publications (3)

Publication Number Publication Date
FI953841A0 FI953841A0 (fi) 1995-08-14
FI953841A7 FI953841A7 (fi) 1996-02-17
FI953841L true FI953841L (fi) 1996-02-17

Family

ID=6525747

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953841A FI953841L (fi) 1994-08-16 1995-08-14 Substituoituja kinoliinijohdannaisia, menetelmä niiden valmistamseksi

Country Status (24)

Country Link
US (1) US5798365A (fi)
EP (1) EP0697405B1 (fi)
JP (1) JP3860618B2 (fi)
KR (1) KR960007567A (fi)
CN (1) CN1123275A (fi)
AT (1) ATE222239T1 (fi)
AU (1) AU710238B2 (fi)
CA (1) CA2156128A1 (fi)
CZ (1) CZ209095A3 (fi)
DE (2) DE4428932A1 (fi)
DK (1) DK0697405T3 (fi)
ES (1) ES2179857T3 (fi)
FI (1) FI953841L (fi)
HR (1) HRP950446A2 (fi)
HU (1) HUT73133A (fi)
IL (1) IL114937A0 (fi)
NO (1) NO306296B1 (fi)
NZ (1) NZ272730A (fi)
PL (1) PL310030A1 (fi)
PT (1) PT697405E (fi)
SI (1) SI9500260A (fi)
SK (1) SK100695A3 (fi)
TW (1) TW407151B (fi)
ZA (1) ZA956798B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7397363B2 (en) * 1993-06-08 2008-07-08 Raymond Anthony Joao Control and/or monitoring apparatus and method
US6658833B2 (en) * 2000-11-09 2003-12-09 Bestrake, Llc Collector and separator apparatus for lawn and garden
AU2005316739A1 (en) * 2004-12-13 2006-06-22 Galileo Pharmaceuticals, Inc. Spiro derivatives as lipoxygenase inhibitors
DE102008022221A1 (de) * 2008-05-06 2009-11-12 Universität des Saarlandes Inhibitoren der humanen Aldosteronsynthase CYP11B2
CA2802492C (en) * 2010-07-02 2018-10-16 Gilead Sciences, Inc. 2-quinolinyl-acetic acid derivatives as hiv antiviral compounds
ES2634490T3 (es) 2010-07-02 2017-09-28 Gilead Sciences, Inc. Derivados de ácido napht-2-ylacetico para tratar el sida
AP2013007249A0 (en) 2011-04-21 2013-11-30 Gilead Sciences Inc Benzothiazole compounds and their pharmaceutical use
WO2013103724A1 (en) 2012-01-04 2013-07-11 Gilead Sciences, Inc. 2- (tert - butoxy) -2- (7 -methylquinolin- 6 - yl) acetic acid derivatives for treating aids
WO2013103738A1 (en) 2012-01-04 2013-07-11 Gilead Sciences, Inc. Napthalene acetic acid derivatives against hiv infection
PH12014500842A1 (en) 2012-04-20 2014-06-09 Gilead Sciences Inc Benzothiazol-6-yl acetic acid derivatives and their use for treating an hiv infection
EP4452255A4 (en) * 2021-12-23 2025-12-31 The Katholieke Univ Leuven SPIROS AND ASSOCIATED ANALOGUES TO INHIBIT YAP/TAZ-TEAD

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2101335A1 (en) * 1991-03-14 1992-09-15 Paul Adrian Aristoff Reissert compounds as anti-hiv agents
DE4142322A1 (de) * 1991-12-20 1993-07-01 Hoechst Ag Chinoxaline, verfahren zu ihrer herstellung und ihreverwendung
TW304945B (fi) * 1992-06-27 1997-05-11 Hoechst Ag

Also Published As

Publication number Publication date
HU9502403D0 (en) 1995-10-30
DE4428932A1 (de) 1996-02-22
PT697405E (pt) 2002-12-31
NO953204D0 (no) 1995-08-15
SK100695A3 (en) 1996-06-05
CA2156128A1 (en) 1996-02-17
CN1123275A (zh) 1996-05-29
FI953841A0 (fi) 1995-08-14
JPH0859621A (ja) 1996-03-05
DE59510318D1 (de) 2002-09-19
TW407151B (en) 2000-10-01
CZ209095A3 (en) 1996-03-13
ATE222239T1 (de) 2002-08-15
FI953841A7 (fi) 1996-02-17
HRP950446A2 (en) 1997-08-31
EP0697405A1 (de) 1996-02-21
ZA956798B (en) 1996-03-19
EP0697405B1 (de) 2002-08-14
SI9500260A (en) 1996-02-29
NZ272730A (en) 1998-01-26
NO953204L (no) 1996-02-19
AU2853195A (en) 1996-02-29
AU710238B2 (en) 1999-09-16
US5798365A (en) 1998-08-25
IL114937A0 (en) 1995-12-08
HUT73133A (en) 1996-06-28
NO306296B1 (no) 1999-10-18
ES2179857T3 (es) 2003-02-01
JP3860618B2 (ja) 2006-12-20
KR960007567A (ko) 1996-03-22
DK0697405T3 (da) 2002-12-16
PL310030A1 (en) 1996-02-19

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