FI971609L - Menetelmä 4a,5,9,10,11,12-heksahydro-6H-bentsofuro-(3a,3,2-ef)(2)-bentsatsepiinijohdannaisten valmistamiseksi - Google Patents

Menetelmä 4a,5,9,10,11,12-heksahydro-6H-bentsofuro-(3a,3,2-ef)(2)-bentsatsepiinijohdannaisten valmistamiseksi Download PDF

Info

Publication number: FI971609L
Authority: FI; Finland
Prior art keywords: benzofuro; hexahydro; preparation; benzazepine derivatives; benzazepine
Prior art date: 1994-10-21

Application number

FI971609A

Other languages

English (en)

Swedish (sv)

Other versions

FI114477B (fi

FI971609A0 (fi

Inventor

Laszlo Czollner

Johannes Froehlich

Ulrich Jordis

Bernhard Kueenburg

Original Assignee

Waldheim Pharmazeutika Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-21

Filing date

1997-04-16

Publication date

1997-06-02

1994-10-21 Priority claimed from AT198094A external-priority patent/AT401058B/de

1997-04-16 Application filed by Waldheim Pharmazeutika Gmbh filed Critical Waldheim Pharmazeutika Gmbh

1997-04-16 Publication of FI971609A0 publication Critical patent/FI971609A0/fi

1997-06-02 Publication of FI971609L publication Critical patent/FI971609L/fi

2004-10-29 Application granted granted Critical

2004-10-29 Publication of FI114477B publication Critical patent/FI114477B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Other In-Based Heterocyclic Compounds (AREA)

FI971609A 1994-10-21 1997-04-16 Menetelmä uusien ja tunnettujen 4a,5,9,10,11,12-heksahydro-6H-bentsofuro-[3a,3,2-ef][2]bentsatsepiinijohdannaisten valmistamiseksi sekä uusia yhdisteitä FI114477B (fi)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
AT198094A AT401058B (de)	1994-10-21	1994-10-21	Verfahren zum herstellen von derivaten des 4a,5, 9,10,11,12,-hexahydro-6h-benzofuro(3a,-3,2-ef) (2)benzazepins
AT198094		1994-10-21
US48710295A	1995-06-07	1995-06-07
US48710295		1995-06-07
AT9500208		1995-10-23
PCT/AT1995/000208 WO1996012692A1 (de)	1994-10-21	1995-10-23	VERFAHREN ZUM HERSTELLEN VON DERIVATEN DES 4a,5,9,10,11,12,-HEXAHYDRO-6H-BENZOFURO[3a,3,2-ef][2]BENZAZEPINS

Publications (3)

Publication Number	Publication Date
FI971609A0 FI971609A0 (fi)	1997-04-16
FI971609L true FI971609L (fi)	1997-06-02
FI114477B FI114477B (fi)	2004-10-29

Family

ID=25597335

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI971609A FI114477B (fi)	1994-10-21	1997-04-16	Menetelmä uusien ja tunnettujen 4a,5,9,10,11,12-heksahydro-6H-bentsofuro-[3a,3,2-ef][2]bentsatsepiinijohdannaisten valmistamiseksi sekä uusia yhdisteitä

Country Status (27)

Country	Link
US (1)	US6043359A (fi)
EP (1)	EP0787115B1 (fi)
JP (1)	JP4187786B2 (fi)
KR (1)	KR100352212B1 (fi)
CN (1)	CN1069624C (fi)
AT (1)	ATE188460T1 (fi)
AU (1)	AU695352B2 (fi)
BG (1)	BG62133B1 (fi)
BR (1)	BR9509406A (fi)
CA (1)	CA2203183C (fi)
CZ (1)	CZ295528B6 (fi)
DE (1)	DE59507585D1 (fi)
DK (1)	DK0787115T3 (fi)
ES (1)	ES2106700T3 (fi)
FI (1)	FI114477B (fi)
GR (2)	GR980300015T1 (fi)
HU (1)	HU217207B (fi)
MX (1)	MX9702892A (fi)
NO (2)	NO313234B1 (fi)
NZ (1)	NZ294191A (fi)
PL (1)	PL184590B1 (fi)
PT (1)	PT787115E (fi)
RO (1)	RO118419B1 (fi)
RU (1)	RU2146258C1 (fi)
SI (1)	SI0787115T1 (fi)
SK (1)	SK283877B6 (fi)
WO (1)	WO1996012692A1 (fi)

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GB9519267D0 (en) *	1995-09-21	1995-11-22	Chiroscience Ltd	Preparation of alkaloids
AT403803B (de)	1996-04-19	1998-05-25	Sanochemia Ltd	Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln
GB9610887D0 (en) *	1996-05-24	1996-07-31	N H S Trust	Process
GB9707413D0 (en) *	1997-04-11	1997-05-28	Chiroscience Ltd	Process
HUP0202233A3 (en) *	2000-03-31	2004-12-28	Sanochemia Pharmazeutika Ag	Derivatives and analogues of galanthamin, their use, pharmaceutical compositions containing them and process for the preparation of them
US6897228B2 (en) *	2000-07-07	2005-05-24	Medicure International Inc.	Pyridoxine and pyridoxal analogues: new uses
WO2002061457A2 (en) *	2001-01-30	2002-08-08	Decharms R Christopher	Methods for physiological monitoring, training, exercise and regulation
DE10129265A1 (de) *	2001-06-18	2003-01-02	Hf Arzneimittelforsch Gmbh	Wirkstoff-Kombination zur medikamentösen Sucht- oder Rauschmitteltherapie
DE10134038A1 (de) *	2001-07-12	2003-02-06	Hf Arzneimittelforsch Gmbh	Wirkstoff-Kombination zur medikamentösen Therapie der Nikotinabhängigkeit
AT414125B (de) *	2003-09-29	2006-09-15	Sanochemia Pharmazeutika Ag	Neue derivate des 4a,5,9,10,11,12-hexahydro- benzofuro(3a,3,2)(2) benzazepin, verfahren zu deren herstellung sowie deren verwendung zur herstellung von arzneimitteln
WO2005030332A2 (de) *	2003-09-29	2005-04-07	Sanochemia Pharmazeutika Ag	Verwendung von galanthamin und seinen derivaten zum herstellen von arzneimitteln
CA2552114A1 (en) *	2003-12-31	2005-07-21	Actavis Group Hf	Solid dosage formulations of galantamine
US20050191349A1 (en) *	2003-12-31	2005-09-01	Garth Boehm	Galantamine formulations
WO2006013546A2 (en) *	2004-07-28	2006-02-09	Ranbaxy Laboratories Limited	Process for the preparation of pure galantamine
WO2006018703A2 (en) *	2004-08-16	2006-02-23	Ranbaxy Laboratories Limited	Processes for preparation of narwedine and its use in the synthesis of galantamine
ATE459627T1 (de) *	2005-05-03	2010-03-15	Medichem Sa	Synthesen und herstellungen von narwedin und verwandten neuen verbindungen
AT504663B1 (de)	2007-02-22	2008-07-15	Sanochemia Pharmazeutika Ag	Verfahren zum herstellen von hochreinen 4a,5,9,10,11,12,-hexahydro-6h-benzofuro(3a,3,2- f)(2) benzazepinen sowie dessen derivaten
NZ580271A (en) *	2007-04-12	2011-03-31	Scinopharm Taiwan Ltd	Process for making galantamine
EP2009015B1 (en)	2007-06-18	2012-01-11	Aurobindo Pharma Limited	Process for the preparation of galantamine hydrobromide
AT507039A1 (de) *	2008-06-26	2010-01-15	Sanochemia Pharmazeutika Ag	Verfahren zum herstellen von hochreinen benzazepinderivaten
DE102008056086A1 (de) *	2008-11-06	2010-05-12	Gp Solar Gmbh	Additiv für alkalische Ätzlösungen, insbesondere für Texturätzlösungen sowie Verfahren zu dessen Herstellung
WO2013160728A1 (en)	2012-04-26	2013-10-31	Alma Mater Studiorum - Universita' Di Bologna	Dual targeting compounds for the treatment of alzheimer's disease
CN102924462B (zh) *	2012-10-24	2015-01-14	华东师范大学	1,2,3,4,5,9-取代苯并吖庚因类化合物的合成方法
CN103345954B (zh) *	2013-06-20	2016-06-08	哈尔滨工业大学	一种高锰酸盐与活性炭联用去除放射性碘污染的水处理方法
CN109336897A (zh) *	2018-12-06	2019-02-15	河南中帅医药科技股份有限公司	一种氢溴酸加兰他敏工业化制备方法
CN112521395B (zh) *	2019-09-17	2023-09-05	鲁南制药集团股份有限公司	一种加兰他敏的制备方法
CN112521364B (zh) *	2019-09-17	2023-09-05	鲁南制药集团股份有限公司	一种加兰他敏中间体化合物v
CN110714208B (zh) *	2019-10-30	2020-12-29	常州工学院	一种电催化制备6-(磺酰甲基)菲啶类化合物的方法
CN118908968B (zh) *	2024-10-09	2025-03-04	威胜生物医药(苏州)股份有限公司	一种加兰他敏中间体衍生物及其催化氧化制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BG28325A1 (en) *	1978-11-21	1980-04-15	Vlakhov	Method of obtaining of enons navedine type and their derivatives
US4290862A (en) *	1979-11-14	1981-09-22	Edinen Centar P Chimia	Method for the preparation of narwedine-type enones
US4663318A (en) *	1986-01-15	1987-05-05	Bonnie Davis	Method of treating Alzheimer's disease
DE3856594D1 (de) *	1987-05-04	2008-11-27	Bonnie Davis	Mittel zur behandlung der alzheimer-krankheit
US5428159A (en) *	1994-04-08	1995-06-27	Ciba-Geigy Corporation	Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine

1995
- 1995-10-23 RO RO97-00721A patent/RO118419B1/ro unknown
- 1995-10-23 CZ CZ19971195A patent/CZ295528B6/cs not_active IP Right Cessation
- 1995-10-23 DK DK95944807T patent/DK0787115T3/da active
- 1995-10-23 NZ NZ294191A patent/NZ294191A/xx not_active IP Right Cessation
- 1995-10-23 WO PCT/AT1995/000208 patent/WO1996012692A1/de not_active Ceased
- 1995-10-23 CA CA002203183A patent/CA2203183C/en not_active Expired - Lifetime
- 1995-10-23 CN CN95196432A patent/CN1069624C/zh not_active Expired - Lifetime
- 1995-10-23 DE DE59507585T patent/DE59507585D1/de not_active Expired - Lifetime
- 1995-10-23 EP EP95944807A patent/EP0787115B1/de not_active Expired - Lifetime
- 1995-10-23 AT AT95944807T patent/ATE188460T1/de active
- 1995-10-23 KR KR1019970702612A patent/KR100352212B1/ko not_active Expired - Lifetime
- 1995-10-23 JP JP51352796A patent/JP4187786B2/ja not_active Expired - Fee Related
- 1995-10-23 AU AU36938/95A patent/AU695352B2/en not_active Expired
- 1995-10-23 PT PT95944807T patent/PT787115E/pt unknown
- 1995-10-23 ES ES95944807T patent/ES2106700T3/es not_active Expired - Lifetime
- 1995-10-23 HU HU9800766A patent/HU217207B/hu unknown
- 1995-10-23 BR BR9509406A patent/BR9509406A/pt not_active Application Discontinuation
- 1995-10-23 RU RU97107848A patent/RU2146258C1/ru active
- 1995-10-23 SI SI9530182T patent/SI0787115T1/xx unknown
- 1995-10-23 SK SK483-97A patent/SK283877B6/sk not_active IP Right Cessation
- 1995-10-23 PL PL95319754A patent/PL184590B1/pl unknown
1997
- 1997-04-10 NO NO19971645A patent/NO313234B1/no not_active IP Right Cessation
- 1997-04-16 BG BG101417A patent/BG62133B1/bg unknown
- 1997-04-16 FI FI971609A patent/FI114477B/fi not_active IP Right Cessation
- 1997-04-18 NO NO971796A patent/NO971796L/no unknown
- 1997-04-18 US US08/839,350 patent/US6043359A/en not_active Expired - Lifetime
- 1997-04-21 MX MX9702892A patent/MX9702892A/es unknown
1998
- 1998-03-31 GR GR980300015T patent/GR980300015T1/el unknown
2000
- 2000-03-15 GR GR20000400665T patent/GR3032965T3/el unknown

Also Published As

Publication number	Publication date
ATE188460T1 (de)	2000-01-15
GR980300015T1 (en)	1998-03-31
SK283877B6 (sk)	2004-04-06
PL319754A1 (en)	1997-08-18
NO971645L (no)	1997-05-07
CZ295528B6 (cs)	2005-08-17
JPH10507457A (ja)	1998-07-21
JP4187786B2 (ja)	2008-11-26
PT787115E (pt)	2000-05-31
WO1996012692A1 (de)	1996-05-02
MX9702892A (es)	1998-07-31
DK0787115T3 (da)	2000-05-08
ES2106700T3 (es)	2000-05-16
RO118419B1 (ro)	2003-05-30
CN1069624C (zh)	2001-08-15
NO971796L (no)	1997-05-28
GR3032965T3 (en)	2000-07-31
CA2203183A1 (en)	1996-05-02
NZ294191A (en)	1998-10-28
BR9509406A (pt)	1998-11-03
ES2106700T1 (es)	1997-11-16
AU695352B2 (en)	1998-08-13
BG62133B1 (bg)	1999-03-31
US6043359A (en)	2000-03-28
DE59507585D1 (de)	2000-02-10
RU2146258C1 (ru)	2000-03-10
HUT77716A (hu)	1998-07-28
NO971645D0 (no)	1997-04-10
EP0787115A1 (de)	1997-08-06
BG101417A (en)	1997-12-30
CN1170395A (zh)	1998-01-14
FI114477B (fi)	2004-10-29
KR100352212B1 (ko)	2003-04-18
SK48397A3 (en)	1997-11-05
SI0787115T1 (en)	2000-04-30
NO313234B1 (no)	2002-09-02
NO971796D0 (no)	1997-04-18
CZ119597A3 (en)	1997-08-13
EP0787115B1 (de)	2000-01-05
AU3693895A (en)	1996-05-15
PL184590B1 (pl)	2002-11-29
CA2203183C (en)	2008-04-08
HU217207B (hu)	1999-12-28
FI971609A0 (fi)	1997-04-16

Publication	Publication Date	Title
FI971609L (fi)	1997-06-02	Menetelmä 4a,5,9,10,11,12-heksahydro-6H-bentsofuro-(3a,3,2-ef)(2)-bentsatsepiinijohdannaisten valmistamiseksi
NO981800L (no)	1998-06-11	FremgangsmÕte for fremstilling av 1,1,1,3,3-pentafluorpentan
FI973281L (fi)	1997-08-08	Menetelmä tiettyjen atsasykloheksapeptidien valmistamiseksi
FI20040310A7 (fi)	2004-02-27	Menetelmä bentsosykloalkyyliatsolitionijohdannaisten valmistamiseksi
FI903752A7 (fi)	1991-02-01	Menetelmä 1,2,3,4-tetrahydro-9-akridiiniamiinin johdannaisten valmistamiseksi
HUP9904034A3 (en)	2001-08-28	New process for the preparation of phenylimidazolidine derivatives
FI911080A7 (fi)	1991-09-09	Menetelmä 1,5-bentsotiatsepiinijohdannaisten valmistamiseksi
HUP9903481A3 (en)	2001-11-28	Process for the preparation of 1-aryl-1-cyanocyclobutane derivatives
FI973644A0 (fi)	1997-09-09	Uusi menetelmä 2,3-dihydrobentsofuranolijohdannaisten valmistamiseksi
NO985535L (no)	1999-01-27	FremgangsmÕte for fremstilling av 1,3-alkandioler
NO304110B1 (no)	1998-10-26	FremgangsmÕte for fremstilling av glutardialdehyd
FI952145L (fi)	1995-11-07	Menetelmä alfa-D-glukopyranosido-1,6-mannitolin ja -sorbitolin valmistamiseksi alfa-D-glukopyrano-sido-1,6-fruktoosista
FI964410A7 (fi)	1996-11-01	Menetelmä 4-amino-delta4-3-ketosteroidien valmistamiseksi 4-nitro-delt a4-3-ketosteroidien kautta
NO179101C (no)	1996-08-07	Fremgangsmåte for fremstilling av dibeskyttet 2,3-hydroksymetyl-cyklobutanol
FI943833A0 (fi)	1994-08-19	Menetelmä 2,3,5,6-tetraklooripyridiinin valmistamiseksi
FI964278A7 (fi)	1996-12-20	Menetelmä 5,6-dihydroksi-2-amino-1,2,3,4-tetrahydronaftaleenin johdann aisten valmistamiseksi
ZA988397B (en)	1999-03-24	Process for the preparation of substituted 5,6-dihydro-2H-pyran-2-ones
FI930237A7 (fi)	1993-07-24	Menetelmä 4,6-dialkoksipyrimidiinien valmistamiseksi
IL118731A0 (en)	1996-10-16	Process for the preparation of 2,2-dialkyl-arylidene-cycloalkanones
FI971964A7 (fi)	1997-05-07	Menetelmä 1-halo-3-trialkyylisilasnyylibentseenijohdannaisten valmista miseksi
HUP9901543A3 (en)	2000-03-28	Process for the preparation of hydroxysulfone derivatives
FI20040505A7 (fi)	2004-04-06	Menetelmä 1,3-dihydro-6-hydroksi-2H-indol-2-oni-johdannaisten valmistamiseksi
NO964519D0 (no)	1996-10-24	Fremgangsmåte for fremstilling av chitosanalkylderivater
IL120556A (en)	2000-11-21	Process for the preparation of 3,3,5-trichloroglutarimide
FI951441L (fi)	1995-09-29	Menetelmä 5-formyyliamino-pyrimidiinien valmistamiseksi

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2004-10-29	FG	Patent granted	Ref document number: 114477 Country of ref document: FI
2015-11-18	MA	Patent expired

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