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NO953204D0 - Substituerte chinolinderivater, fremgangsmåte for deres fremstilling og deres anvendelse - Google Patents

Substituerte chinolinderivater, fremgangsmåte for deres fremstilling og deres anvendelse

Info

Publication number
NO953204D0
NO953204D0 NO953204A NO953204A NO953204D0 NO 953204 D0 NO953204 D0 NO 953204D0 NO 953204 A NO953204 A NO 953204A NO 953204 A NO953204 A NO 953204A NO 953204 D0 NO953204 D0 NO 953204D0
Authority
NO
Norway
Prior art keywords
alkyl
cooh
cycloalkyl
preparation
formula
Prior art date
Application number
NO953204A
Other languages
English (en)
Other versions
NO953204L (no
NO306296B1 (no
Inventor
Reinhard Kirsch
Jorg-Peter Kleim
Gunther Riess
Manfred Rosner
Irvin Winkler
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO953204D0 publication Critical patent/NO953204D0/no
Publication of NO953204L publication Critical patent/NO953204L/no
Publication of NO306296B1 publication Critical patent/NO306296B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
NO953204A 1994-08-16 1995-08-15 Substituerte kinolinderivater og deres anvendelse samt legemidler inneholdende derilvatene NO306296B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4428932A DE4428932A1 (de) 1994-08-16 1994-08-16 Substituierte-Chinolinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung

Publications (3)

Publication Number Publication Date
NO953204D0 true NO953204D0 (no) 1995-08-15
NO953204L NO953204L (no) 1996-02-19
NO306296B1 NO306296B1 (no) 1999-10-18

Family

ID=6525747

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953204A NO306296B1 (no) 1994-08-16 1995-08-15 Substituerte kinolinderivater og deres anvendelse samt legemidler inneholdende derilvatene

Country Status (24)

Country Link
US (1) US5798365A (no)
EP (1) EP0697405B1 (no)
JP (1) JP3860618B2 (no)
KR (1) KR960007567A (no)
CN (1) CN1123275A (no)
AT (1) ATE222239T1 (no)
AU (1) AU710238B2 (no)
CA (1) CA2156128A1 (no)
CZ (1) CZ209095A3 (no)
DE (2) DE4428932A1 (no)
DK (1) DK0697405T3 (no)
ES (1) ES2179857T3 (no)
FI (1) FI953841L (no)
HR (1) HRP950446A2 (no)
HU (1) HUT73133A (no)
IL (1) IL114937A0 (no)
NO (1) NO306296B1 (no)
NZ (1) NZ272730A (no)
PL (1) PL310030A1 (no)
PT (1) PT697405E (no)
SI (1) SI9500260A (no)
SK (1) SK100695A3 (no)
TW (1) TW407151B (no)
ZA (1) ZA956798B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7397363B2 (en) * 1993-06-08 2008-07-08 Raymond Anthony Joao Control and/or monitoring apparatus and method
US6658833B2 (en) * 2000-11-09 2003-12-09 Bestrake, Llc Collector and separator apparatus for lawn and garden
AU2005316739A1 (en) * 2004-12-13 2006-06-22 Galileo Pharmaceuticals, Inc. Spiro derivatives as lipoxygenase inhibitors
DE102008022221A1 (de) * 2008-05-06 2009-11-12 Universität des Saarlandes Inhibitoren der humanen Aldosteronsynthase CYP11B2
CA2802492C (en) * 2010-07-02 2018-10-16 Gilead Sciences, Inc. 2-quinolinyl-acetic acid derivatives as hiv antiviral compounds
ES2634490T3 (es) 2010-07-02 2017-09-28 Gilead Sciences, Inc. Derivados de ácido napht-2-ylacetico para tratar el sida
AP2013007249A0 (en) 2011-04-21 2013-11-30 Gilead Sciences Inc Benzothiazole compounds and their pharmaceutical use
WO2013103724A1 (en) 2012-01-04 2013-07-11 Gilead Sciences, Inc. 2- (tert - butoxy) -2- (7 -methylquinolin- 6 - yl) acetic acid derivatives for treating aids
WO2013103738A1 (en) 2012-01-04 2013-07-11 Gilead Sciences, Inc. Napthalene acetic acid derivatives against hiv infection
PH12014500842A1 (en) 2012-04-20 2014-06-09 Gilead Sciences Inc Benzothiazol-6-yl acetic acid derivatives and their use for treating an hiv infection
EP4452255A4 (en) * 2021-12-23 2025-12-31 The Katholieke Univ Leuven SPIROS AND ASSOCIATED ANALOGUES TO INHIBIT YAP/TAZ-TEAD

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2101335A1 (en) * 1991-03-14 1992-09-15 Paul Adrian Aristoff Reissert compounds as anti-hiv agents
DE4142322A1 (de) * 1991-12-20 1993-07-01 Hoechst Ag Chinoxaline, verfahren zu ihrer herstellung und ihreverwendung
TW304945B (no) * 1992-06-27 1997-05-11 Hoechst Ag

Also Published As

Publication number Publication date
HU9502403D0 (en) 1995-10-30
DE4428932A1 (de) 1996-02-22
PT697405E (pt) 2002-12-31
SK100695A3 (en) 1996-06-05
CA2156128A1 (en) 1996-02-17
CN1123275A (zh) 1996-05-29
FI953841A0 (fi) 1995-08-14
JPH0859621A (ja) 1996-03-05
DE59510318D1 (de) 2002-09-19
TW407151B (en) 2000-10-01
CZ209095A3 (en) 1996-03-13
ATE222239T1 (de) 2002-08-15
FI953841A7 (fi) 1996-02-17
HRP950446A2 (en) 1997-08-31
EP0697405A1 (de) 1996-02-21
ZA956798B (en) 1996-03-19
EP0697405B1 (de) 2002-08-14
SI9500260A (en) 1996-02-29
NZ272730A (en) 1998-01-26
NO953204L (no) 1996-02-19
AU2853195A (en) 1996-02-29
AU710238B2 (en) 1999-09-16
US5798365A (en) 1998-08-25
IL114937A0 (en) 1995-12-08
HUT73133A (en) 1996-06-28
FI953841L (fi) 1996-02-17
NO306296B1 (no) 1999-10-18
ES2179857T3 (es) 2003-02-01
JP3860618B2 (ja) 2006-12-20
KR960007567A (ko) 1996-03-22
DK0697405T3 (da) 2002-12-16
PL310030A1 (en) 1996-02-19

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN FEBRUARY 2002