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FI944729L - Perhydroisoindolijohdannaiset substanssi P:n antagonisteina - Google Patents

Perhydroisoindolijohdannaiset substanssi P:n antagonisteina Download PDF

Info

Publication number
FI944729L
FI944729L FI944729A FI944729A FI944729L FI 944729 L FI944729 L FI 944729L FI 944729 A FI944729 A FI 944729A FI 944729 A FI944729 A FI 944729A FI 944729 L FI944729 L FI 944729L
Authority
FI
Finland
Prior art keywords
antagonists
substance
perhydroisoindole derivatives
perhydroisoindole
derivatives
Prior art date
Application number
FI944729A
Other languages
English (en)
Swedish (sv)
Other versions
FI944729A0 (fi
FI105023B (fi
Inventor
Daniel Achard
Serge Grisoni
Jean-Luc Malleron
Jean-Francois Peyronel
Michael Tabart
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI944729A0 publication Critical patent/FI944729A0/fi
Publication of FI944729L publication Critical patent/FI944729L/fi
Application granted granted Critical
Publication of FI105023B publication Critical patent/FI105023B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI944729A 1992-04-10 1994-10-07 Menetelmä terapeuttisesti käyttökelpoisten difenyyli-4-perhydroisoindolijohdannaisten valmistamiseksi FI105023B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR929204390A FR2689888B1 (fr) 1992-04-10 1992-04-10 Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR9204390 1992-04-10
FR9300352 1993-01-15
PCT/FR1993/000352 WO1993021155A1 (fr) 1992-04-10 1993-04-08 Derives de perhydroisoindole comme antagonistes de la substance p

Publications (3)

Publication Number Publication Date
FI944729A0 FI944729A0 (fi) 1994-10-07
FI944729L true FI944729L (fi) 1994-10-07
FI105023B FI105023B (fi) 2000-05-31

Family

ID=9428707

Family Applications (1)

Application Number Title Priority Date Filing Date
FI944729A FI105023B (fi) 1992-04-10 1994-10-07 Menetelmä terapeuttisesti käyttökelpoisten difenyyli-4-perhydroisoindolijohdannaisten valmistamiseksi

Country Status (24)

Country Link
US (1) US5484804A (fi)
EP (1) EP0635003B1 (fi)
JP (1) JP3205557B2 (fi)
KR (1) KR950700880A (fi)
AT (1) ATE167472T1 (fi)
AU (1) AU667214B2 (fi)
CA (1) CA2133840A1 (fi)
CZ (1) CZ284213B6 (fi)
DE (1) DE69319235T2 (fi)
DK (1) DK0635003T3 (fi)
ES (1) ES2118232T3 (fi)
FI (1) FI105023B (fi)
FR (1) FR2689888B1 (fi)
HU (1) HUT71354A (fi)
IL (1) IL105255A (fi)
MX (1) MX9301986A (fi)
NO (1) NO300417B1 (fi)
NZ (1) NZ251730A (fi)
PL (1) PL172754B1 (fi)
RU (1) RU2127260C1 (fi)
SK (1) SK279032B6 (fi)
TW (1) TW234119B (fi)
WO (1) WO1993021155A1 (fi)
ZA (1) ZA932527B (fi)

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* Cited by examiner, † Cited by third party
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FR2700472B1 (fr) 1993-01-19 1995-02-17 Rhone Poulenc Rorer Sa Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2.
FR2703679B1 (fr) * 1993-04-05 1995-06-23 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2709752B1 (fr) * 1993-07-30 1995-10-06 Rhone Poulenc Rorer Sa Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2710913B1 (fr) * 1993-10-07 1995-11-24 Rhone Poulenc Rorer Sa Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
TW365603B (en) * 1993-07-30 1999-08-01 Rhone Poulenc Rorer Sa Novel perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them
FR2710842B1 (fr) * 1993-10-07 1995-11-24 Rhone Poulenc Rorer Sa Nouvelle application thérapeutique de dérivés de perhydroisoindole.
FR2725900B1 (fr) * 1994-10-21 1997-07-18 Sanofi Sa Utilisation d'antagonistes des recepteurs nk1 pour la preparation de medicaments a action cardioregulatrice
FR2727411B1 (fr) * 1994-11-30 1997-01-03 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent
US6096776A (en) * 1995-01-17 2000-08-01 Qlt Phototherapeutics, Inc. Green porphyrins as immunomodulators
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DE19636150A1 (de) * 1996-09-06 1998-03-12 Asta Medica Ag N-substituierte Indol-3-glyoxylamide mit antiasthmatischer, antiallergischer und immunsuppressiver/immunmodulierender Wirkung
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Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
FR514273A (fr) * 1920-04-23 1921-03-07 Georges Loutz Bougie d'allumage électrique pour moteurs à explosions
US4042707A (en) * 1976-02-19 1977-08-16 E. I. Du Pont De Nemours And Company 3α-Arylhydroisoindoles
FR2654725B1 (fr) * 1989-11-23 1992-02-14 Rhone Poulenc Sante Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2676442B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2689889B1 (fr) * 1992-04-10 1994-06-10 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, et leur preparation.

Also Published As

Publication number Publication date
FI944729A0 (fi) 1994-10-07
FI105023B (fi) 2000-05-31
CZ248294A3 (en) 1995-11-15
EP0635003B1 (fr) 1998-06-17
US5484804A (en) 1996-01-16
SK279032B6 (sk) 1998-05-06
AU3956593A (en) 1993-11-18
DE69319235T2 (de) 1999-01-07
PL172754B1 (pl) 1997-11-28
ES2118232T3 (es) 1998-09-16
FR2689888B1 (fr) 1994-06-10
RU94045855A (ru) 1996-09-10
HUT71354A (en) 1995-11-28
IL105255A (en) 1997-02-18
ATE167472T1 (de) 1998-07-15
MX9301986A (es) 1994-05-31
NO300417B1 (no) 1997-05-26
JPH07505410A (ja) 1995-06-15
DE69319235D1 (de) 1998-07-23
WO1993021155A1 (fr) 1993-10-28
ZA932527B (en) 1993-11-08
RU2127260C1 (ru) 1999-03-10
FR2689888A1 (fr) 1993-10-15
JP3205557B2 (ja) 2001-09-04
NO943692L (no) 1994-10-03
NZ251730A (en) 1995-08-28
DK0635003T3 (da) 1999-02-15
AU667214B2 (en) 1996-03-14
NO943692D0 (no) 1994-10-03
IL105255A0 (en) 1993-08-18
EP0635003A1 (fr) 1995-01-25
CZ284213B6 (cs) 1998-09-16
TW234119B (fi) 1994-11-11
CA2133840A1 (fr) 1993-10-28
SK122094A3 (en) 1995-05-10
HU9402911D0 (en) 1995-01-30
KR950700880A (ko) 1995-02-20

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