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FI900296A0 - Foerfarande foer framstaellning av pre- insulin. - Google Patents

Foerfarande foer framstaellning av pre- insulin.

Info

Publication number
FI900296A0
FI900296A0 FI900296A FI900296A FI900296A0 FI 900296 A0 FI900296 A0 FI 900296A0 FI 900296 A FI900296 A FI 900296A FI 900296 A FI900296 A FI 900296A FI 900296 A0 FI900296 A0 FI 900296A0
Authority
FI
Finland
Prior art keywords
insulin
acid
residue
amino
redox system
Prior art date
Application number
FI900296A
Other languages
English (en)
Other versions
FI900296A7 (fi
Inventor
Michael Doerschug
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI900296A0 publication Critical patent/FI900296A0/fi
Publication of FI900296A7 publication Critical patent/FI900296A7/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Glass Compositions (AREA)
  • Steroid Compounds (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FI900296A 1989-01-21 1990-01-18 Menetelmä esi-insuliinin valmistamiseksi FI900296A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3901719A DE3901719A1 (de) 1989-01-21 1989-01-21 Verfahren zur herstellung eines insulinvorlaeufers

Publications (2)

Publication Number Publication Date
FI900296A0 true FI900296A0 (fi) 1990-01-18
FI900296A7 FI900296A7 (fi) 1990-07-22

Family

ID=6372512

Family Applications (1)

Application Number Title Priority Date Filing Date
FI900296A FI900296A7 (fi) 1989-01-21 1990-01-18 Menetelmä esi-insuliinin valmistamiseksi

Country Status (17)

Country Link
EP (1) EP0381958B1 (fi)
JP (1) JPH02233699A (fi)
AT (1) ATE126808T1 (fi)
AU (1) AU624894B2 (fi)
CA (1) CA2008245A1 (fi)
DE (2) DE3901719A1 (fi)
DK (1) DK0381958T3 (fi)
ES (1) ES2078249T3 (fi)
FI (1) FI900296A7 (fi)
GR (1) GR3017591T3 (fi)
HU (1) HU208704B (fi)
IE (1) IE900217L (fi)
IL (1) IL93115A (fi)
NO (1) NO178861C (fi)
NZ (1) NZ232178A (fi)
PT (1) PT92907B (fi)
ZA (1) ZA90396B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3901718A1 (de) * 1989-01-21 1990-07-26 Hoechst Ag Verfahren zur renaturierung falscher rekombinanten von insulinvorlaeufern
WO1992004382A1 (en) * 1990-09-05 1992-03-19 Bunge (Australia) Pty. Ltd. Solubilization of proteins in active forms
ATE148710T1 (de) * 1992-12-02 1997-02-15 Hoechst Ag Verfahren zur gewinnung von proinsulin mit korrekt verbundenen cystinbrücken
CA2208095C (en) * 1994-12-29 2006-11-28 Bio-Technology General Corp. Generation of human insulin
KR100253916B1 (ko) * 1997-12-29 2000-05-01 김충환 사람 인슐린 전구체의 제조방법
EP1242610A1 (en) 1999-12-22 2002-09-25 Novo Nordisk A/S Method for extractive refolding of scrambledsingle-chain polypeptides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1154435A (en) * 1980-03-27 1983-09-27 Bruce H. Frank Process for producing an insulin precursor
DE3501641A1 (de) * 1985-01-19 1986-07-24 Hoechst Ag, 6230 Frankfurt Verfahren zur gewinnung von insulin-vorlaeufern aus reaktionsgemischen, die bei der faltung von insulin-vorlaeufern aus den entsprechenden s-sulfonaten anfallen
DE3901718A1 (de) * 1989-01-21 1990-07-26 Hoechst Ag Verfahren zur renaturierung falscher rekombinanten von insulinvorlaeufern

Also Published As

Publication number Publication date
IL93115A (en) 1995-07-31
DE3901719A1 (de) 1990-07-26
IE900217L (en) 1990-07-21
DE59009540D1 (de) 1995-09-28
NO900278D0 (no) 1990-01-19
NO178861C (no) 1996-06-19
ES2078249T3 (es) 1995-12-16
PT92907A (pt) 1990-07-31
EP0381958B1 (de) 1995-08-23
HUT54389A (en) 1991-02-28
ATE126808T1 (de) 1995-09-15
IL93115A0 (en) 1990-11-05
EP0381958A2 (de) 1990-08-16
NO178861B (no) 1996-03-11
HU208704B (en) 1993-12-28
PT92907B (pt) 1995-12-29
AU4862190A (en) 1990-07-26
CA2008245A1 (en) 1990-07-21
ZA90396B (en) 1990-09-26
JPH02233699A (ja) 1990-09-17
NZ232178A (en) 1991-10-25
GR3017591T3 (en) 1995-12-31
HU900197D0 (en) 1990-03-28
NO900278L (no) 1990-07-23
FI900296A7 (fi) 1990-07-22
EP0381958A3 (de) 1991-07-24
AU624894B2 (en) 1992-06-25
DK0381958T3 (da) 1995-12-18

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Legal Events

Date Code Title Description
FA Application withdrawn [patent]

Owner name: HOECHST AKTIENGESELLSCHAFT