FI905839L - Menetelmä uusien terapeuttisesti käyttökelpoisten trisyklisten, typpipitoisten yhdisteiden valmistamiseksi - Google Patents

Menetelmä uusien terapeuttisesti käyttökelpoisten trisyklisten, typpipitoisten yhdisteiden valmistamiseksi Download PDF

Info

Publication number: FI905839L
Authority: FI; Finland
Prior art keywords: containing compounds; therapeutically useful; preparing novel; novel therapeutically; tricyclic nitrogen
Prior art date: 1989-11-28

Application number

FI905839A

Other languages

English (en)

Swedish (sv)

Other versions

FI905839A0 (fi

FI98367B (fi

FI98367C (fi

Inventor

Jacob Berger

Robin D Clark

Richard M Eglen

William L Smith

Klaus K Weinhardt

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-28

Filing date

1990-11-27

Publication date

1991-05-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23755479&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI905839(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-11-27 Application filed by Syntex Inc filed Critical Syntex Inc

1990-11-27 Publication of FI905839A0 publication Critical patent/FI905839A0/fi

1991-05-29 Publication of FI905839L publication Critical patent/FI905839L/fi

1997-02-28 Publication of FI98367B publication Critical patent/FI98367B/fi

1997-06-10 Application granted granted Critical

1997-06-10 Publication of FI98367C publication Critical patent/FI98367C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Anesthesiology (AREA)
Nutrition Science (AREA)
Otolaryngology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Saccharide Compounds (AREA)

FI905839A 1989-11-28 1990-11-27 Menetelmä uusien terapeuttisesti käyttökelpoisten trisyklisten, typpipitoisten yhdisteiden valmistamiseksi FI98367C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US44208289A	1989-11-28	1989-11-28
US44208289		1989-11-28

Publications (4)

Publication Number	Publication Date
FI905839A0 FI905839A0 (fi)	1990-11-27
FI905839L true FI905839L (fi)	1991-05-29
FI98367B FI98367B (fi)	1997-02-28
FI98367C FI98367C (fi)	1997-06-10

Family

ID=23755479

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI905839A FI98367C (fi)	1989-11-28	1990-11-27	Menetelmä uusien terapeuttisesti käyttökelpoisten trisyklisten, typpipitoisten yhdisteiden valmistamiseksi

Country Status (23)

Country	Link
US (1)	US5202333A (fi)
EP (1)	EP0430190B1 (fi)
JP (1)	JPH0662607B2 (fi)
KR (1)	KR970007917B1 (fi)
AT (1)	ATE124698T1 (fi)
AU (1)	AU642178B2 (fi)
BR (1)	BR1100680A (fi)
CA (1)	CA2030718C (fi)
DE (2)	DE122005000027I2 (fi)
DK (1)	DK0430190T3 (fi)
ES (1)	ES2075121T3 (fi)
FI (1)	FI98367C (fi)
HK (1)	HK36097A (fi)
HU (1)	HU218654B (fi)
IE (1)	IE68434B1 (fi)
IL (2)	IL96486A (fi)
LU (1)	LU91162I2 (fi)
NL (1)	NL300194I1 (fi)
NO (2)	NO175309C (fi)
NZ (1)	NZ236225A (fi)
PL (3)	PL166277B1 (fi)
PT (1)	PT96001B (fi)
ZA (1)	ZA909529B (fi)

Families Citing this family (74)

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WO2019038656A1 (en)	2017-08-21	2019-02-28	Leiutis Pharmaceuticals Pvt, Ltd	NEW TRIPLE COMBINATION FORMULATIONS FOR ANTIEMETIC THERAPY
EP4385497A1 (en)	2022-12-12	2024-06-19	Alfred E. Tiefenbacher (GmbH & Co. KG)	Antioxidant-free fixed dose combination of netupitant and palonosetron
EP4633612A1 (en)	2022-12-12	2025-10-22	Alfred E. Tiefenbacher (GmbH & Co. KG)	Fixed dose combination comprising netupitant and palonosetron
EP4633608A1 (en)	2022-12-12	2025-10-22	Alfred E. Tiefenbacher (GmbH & Co. KG)	Antioxidant-free fixed dose combination of netupitant and palonosetron
EP4385500A1 (en)	2022-12-12	2024-06-19	Alfred E. Tiefenbacher (GmbH & Co. KG)	Fixed dose combination comprising netupitant and palonosetron

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US3896132A (en) *	1969-08-19	1975-07-22	Hoffmann La Roche	Process for preparing 1,2,3,8,9,9a-hexahydro-5,6-dialkoxy-1-alkyl-benzo(d,e)quinolin-7-ore compounds
US4309543A (en) *	1980-03-17	1982-01-05	Dynapol	Process for preparing cyclic amides
EP0093488A3 (en) *	1982-03-18	1984-05-23	Beecham Group Plc	Nortropyl benzopyrrolinone compounds, process for their preparation and pharmaceutical compositions containing them
US4571396A (en) *	1984-04-16	1986-02-18	Warner-Lambert Company	Antibacterial agents
WO1988004292A1 (en) *	1986-12-11	1988-06-16	The Upjohn Company	Antipsychotic amino-polyhydro-benz-(iso)quinolines and intermediates
ATE108791T1 (de) *	1987-11-04	1994-08-15	Beecham Group Plc	Neue 4-oxobenzotriazine und 4-oxochinazoline.
NZ236225A (en) *	1989-11-28	1992-09-25	Syntex Inc	Azabicyclic-substituted isoquinoline derivatives, intermediates and pharmaceutical compositions
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US5189041A (en) *	1990-11-16	1993-02-23	Syntex (U.S.A.) Inc.	Tricyclic 5-ht3 receptor antagonists

1990
- 1990-11-27 NZ NZ236225A patent/NZ236225A/en unknown
- 1990-11-27 IL IL9648690A patent/IL96486A/en active Protection Beyond IP Right Term
- 1990-11-27 DE DE200512000027 patent/DE122005000027I2/de active Active
- 1990-11-27 EP EP90122689A patent/EP0430190B1/en not_active Expired - Lifetime
- 1990-11-27 PL PL90303661A patent/PL166277B1/pl unknown
- 1990-11-27 HU HU670/90A patent/HU218654B/hu active Protection Beyond IP Right Term
- 1990-11-27 FI FI905839A patent/FI98367C/fi active Protection Beyond IP Right Term
- 1990-11-27 AU AU66963/90A patent/AU642178B2/en not_active Expired
- 1990-11-27 IL IL11062290A patent/IL110622A/en not_active IP Right Cessation
- 1990-11-27 NO NO905120A patent/NO175309C/no not_active IP Right Cessation
- 1990-11-27 DK DK90122689.4T patent/DK0430190T3/da active
- 1990-11-27 JP JP2328764A patent/JPH0662607B2/ja not_active Expired - Fee Related
- 1990-11-27 PT PT96001A patent/PT96001B/pt not_active IP Right Cessation
- 1990-11-27 PL PL90303660A patent/PL166267B1/pl unknown
- 1990-11-27 AT AT90122689T patent/ATE124698T1/de active
- 1990-11-27 DE DE69020694T patent/DE69020694T2/de not_active Expired - Lifetime
- 1990-11-27 CA CA002030718A patent/CA2030718C/en not_active Expired - Lifetime
- 1990-11-27 KR KR1019900019275A patent/KR970007917B1/ko not_active Expired - Lifetime
- 1990-11-27 PL PL90287961A patent/PL166272B1/pl unknown
- 1990-11-27 ZA ZA909529A patent/ZA909529B/xx unknown
- 1990-11-27 IE IE426990A patent/IE68434B1/en not_active IP Right Cessation
- 1990-11-27 ES ES90122689T patent/ES2075121T3/es not_active Expired - Lifetime
1991
- 1991-05-22 US US07/704,565 patent/US5202333A/en not_active Expired - Lifetime
1997
- 1997-03-20 HK HK36097A patent/HK36097A/en not_active IP Right Cessation
- 1997-05-08 BR BR1100680-3A patent/BR1100680A/pt active IP Right Grant
2005
- 2005-04-18 LU LU91162C patent/LU91162I2/fr unknown
- 2005-04-20 NL NL300194C patent/NL300194I1/nl unknown
- 2005-09-21 NO NO2005023C patent/NO2005023I2/no unknown

Also Published As

Publication number	Publication date
NO905120D0 (no)	1990-11-27
KR910009699A (ko)	1991-06-28
EP0430190A3 (en)	1992-01-22
HUT56368A (en)	1991-08-28
NO2005023I1 (no)	2005-10-03
LU91162I2 (fr)	2005-06-20
PL287961A1 (en)	1991-12-02
HU907660D0 (en)	1991-06-28
DE69020694D1 (de)	1995-08-10
NO2005023I2 (no)	2009-10-05
IL96486A0 (en)	1991-08-16
CA2030718A1 (en)	1991-05-29
ATE124698T1 (de)	1995-07-15
NL300194I2 (nl)	2005-07-01
NO175309B (no)	1994-06-20
PL166272B1 (pl)	1995-04-28
KR970007917B1 (ko)	1997-05-17
IL110622A (en)	1995-03-30
EP0430190A2 (en)	1991-06-05
HK36097A (en)	1997-03-27
NL300194I1 (nl)	2005-07-01
IE904269A1 (en)	1991-06-05
FI905839A0 (fi)	1990-11-27
PL166277B1 (pl)	1995-04-28
EP0430190B1 (en)	1995-07-05
IL96486A (en)	1995-03-30
HU218654B (hu)	2000-10-28
JPH03176486A (ja)	1991-07-31
ZA909529B (en)	1992-08-26
PT96001B (pt)	1998-01-30
FI98367B (fi)	1997-02-28
NO905120L (no)	1991-05-29
PL166267B1 (pl)	1995-04-28
FI98367C (fi)	1997-06-10
BR1100680A (pt)	2000-02-08
IE68434B1 (en)	1996-06-12
ES2075121T3 (es)	1995-10-01
DE122005000027I2 (de)	2006-03-16
JPH0662607B2 (ja)	1994-08-17
NO175309C (no)	1994-09-28
DE69020694T2 (de)	1996-01-18
DE122005000027I1 (de)	2005-08-04
PT96001A (pt)	1991-09-30
NZ236225A (en)	1992-09-25
US5202333A (en)	1993-04-13
AU642178B2 (en)	1993-10-14
AU6696390A (en)	1991-06-06
DK0430190T3 (da)	1995-08-21
CA2030718C (en)	1998-05-12

Publication	Publication Date	Title
FI905839L (fi)	1991-05-29	Menetelmä uusien terapeuttisesti käyttökelpoisten trisyklisten, typpipitoisten yhdisteiden valmistamiseksi
PT86866A (pt)	1988-03-01	Process for preparing piperazinyl-heterocyclic compounds
FI906438L (fi)	1991-06-30	Menetelmä uusien, terapeuttisesti käyttökelpoisten A-nor-steroidi-3-karboksyylihappojohdannaisten valmistamiseksi
FI20000648A7 (fi)	2000-03-20	Menetelmä terapeuttisesti käyttökelpoisen yhdisteen valmistamiseksi, joka sisältää 1-okso-2-isokinoliiniin perustuvan keskuksen
FI906045A7 (fi)	1991-06-09	Typpipitoisia spirosyklisiä yhdisteitä
FI885409A7 (fi)	1989-05-24	Menetelmä uusien terapeuttisesti käyttökelpoisten pyridatsiiniamiinijohdannaisten valmistamiseksi
FI883632L (fi)	1989-02-05	Menetelmä uusien, terapeuttisesti käyttökelpoisten eetterien valmistamiseksi
FI893405L (fi)	1989-07-13	Menetelmä kinoloniyhdisteiden valmistamiseksi
FI916017L (fi)	1992-06-22	Menetelmä terapeuttisesti käyttökelpoisten amino- ja nitrosubstituoitujen trisyklisten yhdisteiden valmistamiseksi
PT87218A (pt)	1988-05-01	Process for preparing substituted pyrroles
FI880467A7 (fi)	1988-08-05	Menetelmä terapeuttisesti käyttökelpoisten substituoitujen 3,4-dihydro-2H-bentsopyraanien valmistamiseksi
FI881525A7 (fi)	1988-10-02	Menetelmä uusien terapeuttisesti käyttökelpoisten N-aryylipiperatsiiniasetamidijohdannaisten valmistamiseksi
FI885560A7 (fi)	1988-11-30	Menetelmä uusien terapeuttisesti käyttökelpoisten bisfenyylialkyylipiperatsiinijohdannaisten valmistamiseksi
FI880468A7 (fi)	1988-08-05	Menetelmä terapeuttisesti käyttökelpoisten N-bentsopyranyylilaktaamien valmistamiseksi
FI911420L (fi)	1991-09-27	Menetelmä terapeuttisesti käyttökelpoisten yhdisteiden valmistamiseksi
FI895800A7 (fi)	1990-06-09	Menetelmä uusien a-syano-b-oksopropioniamidien valmistamiseksi
FI960332A7 (fi)	1996-01-24	Menetelmä substituoitujan 4,6-diamino-5-syanopyrinidiinien valmistamiseksi
FI901775A7 (fi)	1990-10-07	Menetelmä uusien terapeuttisesti käyttökelpoisten tiourasiilijohdannaisten valmistamiseksi
FI872249A7 (fi)	1987-11-24	Menetelmä dopamiini- -hydroksylaasia inhiboivien yhdisteiden valmistamiseksi.
FI902110A7 (fi)	1990-10-30	Menetelmä peneemiyhdisteiden valmistamiseksi
FI903754A7 (fi)	1991-01-28	Menetelmä terapeuttisesti käyttökelpoisten lysogangliosidijohdannaisten valmistamiseksi
FI901098A7 (fi)	1990-09-04	N-allyylimetatrifluorometyylianiliinin valmistusmenetelmä
FI905255A7 (fi)	1991-04-26	Menetelmä uusien terapeuttisesti käyttökelpoisten triatsolojohdannaisten valmistamiseksi
FI904359A7 (fi)	1991-03-07	Menetelmä uusien terapeuttisesti käyttökelpoisten substituoitujen aminopyridiinien valmistamiseksi
FI922342A7 (fi)	1992-05-22	Menetelmä terapeuttisesti käyttökelpoisten 3-fenyyliglutarimidijohdannaisten valmistamiseksi

Legal Events

Date	Code	Title	Description
1997-02-03	BB	Publication of examined application
2004-08-31	FG	Patent granted	Owner name: SYNTEX (U.S.A.) INC.
2005-04-18	SPCF	Supplementary protection certificate application filed	Spc suppl protection certif: L20050012
2005-06-29	PC	Transfer of assignment of patent	Owner name: ROCHE PALO ALTO LLC Free format text: ROCHE PALO ALTO LLC
2008-10-15	SPCG	Supplementary protection certificate granted	Spc suppl protection certif: NUMBER:225