FI883997L - Förfarande för framställning av terapeutiskt användbara substituerade 2-fenyl-4-kinolinkarboxylsyror - Google Patents

Förfarande för framställning av terapeutiskt användbara substituerade 2-fenyl-4-kinolinkarboxylsyror Download PDF

Info

Publication number: FI883997L
Authority: FI; Finland
Prior art keywords: phenyl; therapeutically useful; quinolinecarboxylic acids; useful substituted; preparing therapeutically
Prior art date: 1987-08-31

Application number

FI883997A

Other languages

English (en)

Finnish (fi)

Other versions

FI92692C (sv

FI883997A0 (sv

FI92692B (sv

Inventor

Leslie H Sutherland

Adolph E Sloboda

Ralph Grassing Child

John F Poletto

Dennis W Powell

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-08-31

Filing date

1988-08-30

Publication date

1989-03-01

1988-08-30 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1988-08-30 Publication of FI883997A0 publication Critical patent/FI883997A0/sv

1989-03-01 Publication of FI883997L publication Critical patent/FI883997L/sv

1994-09-15 Application granted granted Critical

1994-09-15 Publication of FI92692B publication Critical patent/FI92692B/sv

1994-12-27 Publication of FI92692C publication Critical patent/FI92692C/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Quinoline Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

FI883997A 1987-08-31 1988-08-30 Förfarande för framställning av terapeutiskt användbara substituerade 2-fenyl-4-kinolinkarboxylsyror FI92692C (sv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US9099687		1987-08-31
US07/090,996 US4847381A (en)	1987-08-31	1987-08-31	2-Phenyl-4-quinoline carboxylic acids

Publications (4)

Publication Number	Publication Date
FI883997A0 FI883997A0 (sv)	1988-08-30
FI883997L true FI883997L (sv)	1989-03-01
FI92692B FI92692B (sv)	1994-09-15
FI92692C FI92692C (sv)	1994-12-27

Family

ID=22225261

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI883997A FI92692C (sv)	1987-08-31	1988-08-30	Förfarande för framställning av terapeutiskt användbara substituerade 2-fenyl-4-kinolinkarboxylsyror

Country Status (24)

Country	Link
US (1)	US4847381A (sv)
EP (1)	EP0305952B1 (sv)
JP (1)	JP2760379B2 (sv)
KR (1)	KR970005909B1 (sv)
AR (1)	AR245698A1 (sv)
AT (1)	ATE90079T1 (sv)
AU (1)	AU613661B2 (sv)
CA (1)	CA1333606C (sv)
CS (1)	CS274434B2 (sv)
DD (1)	DD282225A5 (sv)
DE (1)	DE3881456T2 (sv)
DK (1)	DK169473B1 (sv)
ES (1)	ES2058191T3 (sv)
FI (1)	FI92692C (sv)
GR (1)	GR3008033T3 (sv)
HU (1)	HU202498B (sv)
IE (1)	IE65148B1 (sv)
IL (1)	IL87457A (sv)
NO (1)	NO174961C (sv)
NZ (1)	NZ225924A (sv)
PH (1)	PH26258A (sv)
PL (1)	PL156232B1 (sv)
PT (1)	PT88365B (sv)
ZA (1)	ZA886443B (sv)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4968701A (en) *	1988-04-26	1990-11-06	E. I. Du Pont De Nemours And Company	4-Quinoline carboxylic acid derivatives useful as immunosuppressive agents
US4918077A (en) *	1989-01-25	1990-04-17	E. I. Du Pont De Nemours & Co., Inc.	3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents
US5204329A (en) *	1990-06-11	1993-04-20	Du Pont Merck Pharmaceutical Company	Treatment of organ transplantation rejection
US5135934A (en) *	1990-07-06	1992-08-04	Du Pont Merck Pharmaceutical Company	3-phenyl-5,6-dihydrobenz(c) acridine-7-carboxylic acids and related compounds as immunosuppressive agents
US5409886A (en) *	1993-02-18	1995-04-25	Mitsui Toatsu Chemicals, Incorporated	3-pyrroline-2-one derivatives and herbicidal compositions containing same
US5428040A (en) *	1993-08-31	1995-06-27	The Du Pont Merck Pharmaceutical Company	Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents
US5578609A (en) *	1994-03-25	1996-11-26	The Dupont Merck Pharmaceutical Company	2-carbocyclic and 2-heterocyclic quinoline-4-carboxylic acids and salts thereof useful as immunosuppressive agents
ID18663A (id)	1996-04-12	1998-04-30	Novartis Ag	Komposisi farmasi berlapis enterik
US6172084B1 (en)	1997-06-19	2001-01-09	Sepracor, Inc.	Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6103905A (en) *	1997-06-19	2000-08-15	Sepracor, Inc.	Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6376670B1 (en)	1997-06-19	2002-04-23	Sepracor Inc.	Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6207679B1 (en)	1997-06-19	2001-03-27	Sepracor, Inc.	Antimicrobial agents uses and compositions related thereto
AU2108099A (en) *	1998-01-30	1999-08-16	Procept, Inc.	Immunosuppressive agents
SE9901366D0 (sv) *	1999-04-16	1999-04-16	Pharmacia & Upjohn Ab	Injector device and method for its operation
US20020121638A1 (en) *	2000-06-30	2002-09-05	Vladimir Grushin	Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such compounds
WO2009016812A1 (ja) *	2007-07-27	2009-02-05	Kowa Company, Ltd.	２－フェニルキノリン－４－カルボン酸誘導体を有効成分とする貧血の予防及び／又は治療剤
AU2014352920A1 (en)	2013-11-22	2016-06-23	Genzyme Corporation	Novel methods for treating neurodegenerative diseases

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2776290A (en) *		1957-01-01		Hydroxy cevchoninates and carboxylic
US2008923A (en) *	1931-07-09	1935-07-23	Graham Patmore L	Cinchoninic acid salts of piperazines
US2077903A (en) *	1933-12-15	1937-04-20	Gen Aniline Works Inc	Process of preparing 3-amino-quinolines
US2486440A (en) *	1946-01-10	1949-11-01	Gen Aniline & Film Corp	Production of phenazonium dyestuff images
BE502610A (sv) *	1950-04-18
US2888346A (en) *	1955-08-22	1959-05-26	Gen Aniline & Film Corp	Ultra-violet absorbing compounds
DE1049701B (sv) *	1957-02-21
FR6592M (sv) *	1967-10-31	1968-12-30
BE794945A (fr) *	1972-02-04	1973-08-02	Sandoz Sa	Application de derives de la quinoleine pour stabiliser des matieres organiques contre les effets de la lumiere ultraviolette
US4009020A (en) *	1975-05-06	1977-02-22	Amchem Products, Inc.	Method of regulating plant growth
SU1109402A1 (ru) *	1982-10-12	1984-08-23	Предприятие П/Я Р-6496	Способ получени производных 2-(хинолил-4)-5-арилоксазола
ZA845594B (en) *	1983-07-22	1986-03-26	Du Pont	Phenylquinolinecarboxylic acids and derivatives as antitumor agents
US4680299A (en) *	1984-04-30	1987-07-14	E.I. Du Pont De Nemours And Company	2-phenyl-4-quinolinecarboxylic acids and pharmaceutical compositions thereof

1987
- 1987-08-31 US US07/090,996 patent/US4847381A/en not_active Expired - Lifetime
1988
- 1988-08-15 IL IL8745788A patent/IL87457A/en not_active IP Right Cessation
- 1988-08-24 NZ NZ225924A patent/NZ225924A/en unknown
- 1988-08-29 PT PT88365A patent/PT88365B/pt not_active IP Right Cessation
- 1988-08-29 EP EP88114061A patent/EP0305952B1/en not_active Expired - Lifetime
- 1988-08-29 ES ES88114061T patent/ES2058191T3/es not_active Expired - Lifetime
- 1988-08-29 PH PH37473A patent/PH26258A/en unknown
- 1988-08-29 AT AT88114061T patent/ATE90079T1/de active
- 1988-08-29 DE DE88114061T patent/DE3881456T2/de not_active Expired - Fee Related
- 1988-08-29 CA CA000575951A patent/CA1333606C/en not_active Expired - Fee Related
- 1988-08-30 NO NO883865A patent/NO174961C/no not_active IP Right Cessation
- 1988-08-30 JP JP63213853A patent/JP2760379B2/ja not_active Expired - Lifetime
- 1988-08-30 AR AR88311798A patent/AR245698A1/es active
- 1988-08-30 AU AU21678/88A patent/AU613661B2/en not_active Ceased
- 1988-08-30 ZA ZA886443A patent/ZA886443B/xx unknown
- 1988-08-30 KR KR1019880011111A patent/KR970005909B1/ko not_active Expired - Fee Related
- 1988-08-30 IE IE262888A patent/IE65148B1/en not_active IP Right Cessation
- 1988-08-30 HU HU884489A patent/HU202498B/hu not_active IP Right Cessation
- 1988-08-30 FI FI883997A patent/FI92692C/sv not_active IP Right Cessation
- 1988-08-30 DK DK482688A patent/DK169473B1/da not_active IP Right Cessation
- 1988-08-31 CS CS587588A patent/CS274434B2/cs unknown
- 1988-08-31 PL PL1988274471A patent/PL156232B1/pl unknown
- 1988-08-31 DD DD88319347A patent/DD282225A5/de not_active IP Right Cessation
1993
- 1993-06-03 GR GR930400370T patent/GR3008033T3/el unknown

Also Published As

Publication number	Publication date
DK482688A (da)	1989-03-01
EP0305952B1 (en)	1993-06-02
AU2167888A (en)	1989-03-02
FI92692C (sv)	1994-12-27
PL156232B1 (en)	1992-02-28
PT88365A (pt)	1989-06-30
AU613661B2 (en)	1991-08-08
PL274471A1 (en)	1989-05-02
EP0305952A1 (en)	1989-03-08
ATE90079T1 (de)	1993-06-15
IE65148B1 (en)	1995-10-04
IE882628L (en)	1989-02-28
NO174961B (no)	1994-05-02
CS587588A2 (en)	1990-06-13
GR3008033T3 (sv)	1993-09-30
CA1333606C (en)	1994-12-20
ES2058191T3 (es)	1994-11-01
KR970005909B1 (ko)	1997-04-22
FI883997A0 (sv)	1988-08-30
PH26258A (en)	1992-04-01
NO883865D0 (no)	1988-08-30
CS274434B2 (en)	1991-04-11
NZ225924A (en)	1991-07-26
KR890003703A (ko)	1989-04-17
DE3881456T2 (de)	1994-01-13
JP2760379B2 (ja)	1998-05-28
HU202498B (en)	1991-03-28
JPH01110673A (ja)	1989-04-27
AR245698A1 (es)	1994-02-28
DE3881456D1 (de)	1993-07-08
DK169473B1 (da)	1994-11-07
DK482688D0 (da)	1988-08-30
IL87457A (en)	1994-08-26
HUT48597A (en)	1989-06-28
IL87457A0 (en)	1989-01-31
US4847381A (en)	1989-07-11
NO174961C (no)	1994-08-10
NO883865L (no)	1989-03-01
ZA886443B (en)	1989-04-26
PT88365B (pt)	1995-03-31
DD282225A5 (de)	1990-09-05
FI92692B (sv)	1994-09-15

Publication	Publication Date	Title
FI885409A7 (sv)	1989-05-24	Förfarande för framställning av nya terapeutiskt användbara pyridazinaminderivat
FI883388L (sv)	1989-01-18	Förfarande för framställning av nya terapeutiskt användbara peptider
FI883249A7 (sv)	1989-01-11	Förfarande för framställning av terapeutiskt användbara 3-desmetylmevalonsyraderivat
PT88596A (pt)	1988-10-01	Process for preparing 2-anilinopyrimidine derivatives useful aspesticidas
PT86866A (pt)	1988-03-01	Process for preparing piperazinyl-heterocyclic compounds
NO176758C (no)	1995-05-24	Analogifremgangsmåte for fremstilling av terapeutiske anvendbare tetrazolyl-bifenylylmetyl-pyrimidiner
FI883064A7 (sv)	1988-12-25	Förfarande för framställning av terapeutiskt användbara heterocykliska föreningar
FI881180L (sv)	1988-09-14	Förfarande för framställning av terapeutiskt användbara tetrahydronaftalenderivat
FI882638L (sv)	1988-12-06	Förfarande för framställning av terapeutiskt användbara boraminosyraderivat
FI880816A7 (sv)	1988-09-24	Förfarande för framställning av nya terapeutiskt användbara kinoxalinderivat
FI875024A7 (sv)	1988-05-15	Förfarande för framställning av terapeutiskt användbara 1-alkyl-6-halogentetrahydronaftalenderivat
FI883426L (sv)	1989-01-21	Förfarande för framställning av en terapeutiskt användbar pentasackarid
FI883997L (sv)	1989-03-01	Förfarande för framställning av terapeutiskt användbara substituerade 2-fenyl-4-kinolinkarboxylsyror
FI884627A7 (sv)	1989-04-10	Förfarande för framställning av nya terapeutiskt användbara dideoxicytidinderivat
FI883603A7 (sv)	1989-02-04	Förfarande för framställning av terapeutiskt användbara 1,4-dihydropyridinderivat
FI893883A7 (sv)	1989-08-17	Förfarande för framställning av terapeutiskt aktiva 7-tetrahydronaftyridin-6-fluor-1,4-dihydro-4-oxo-kinolin-3-karboxylsyror
FI902435A7 (sv)	1990-11-17	Förfarande för framställning av 2-asylalkanoinsyror
FI883672A7 (sv)	1989-02-08	Förfarande för framställning av terapeutiskt användbara aminoalkoxifenylderivat
FI884553A7 (sv)	1989-04-06	Analogiförfarande för framställning av terapeutiskt användbara 9-aminotetrahydroakridinderivat
NO174959C (no)	1994-08-10	Analogifremgangsmåte for fremstilling av terapeutisk aktive N-aminobutyl-N-fenyl-arylamidderivater
FI880467A7 (sv)	1988-08-05	Förfarande för framställning av terapeutiskt användbara substituerade 3,4-dihydro-2H-benzopyraner
FI881525A7 (sv)	1988-10-02	Förfarande för framställning av nya terapeutiskt användbara N-arylpiperazinacetamidderivat
FI885560A7 (sv)	1988-11-30	Förfarande för framställning av nya terapeutiskt användbara bisfenylalkylpiperazinderivat
FI880716A7 (sv)	1988-08-18	Förfarande för framställning av terapeutiskt användbara arylpiperazinylalkylenfenylsubstituerade heterocykliska föreningar
FI893003L (sv)	1989-12-21	Förfarande för framställning av terapeutiskt användbara neplanocinderivat

Legal Events

Date	Code	Title	Description
1994-08-16	BB	Publication of examined application
2004-08-31	MM	Patent lapsed	Owner name: AMERICAN CYANAMID COMPANY