PT88365A - Processo para a preparacao de acidos 2-fenil-4-quinolino-carboxilicos substituidos - Google Patents

Processo para a preparacao de acidos 2-fenil-4-quinolino-carboxilicos substituidos

Info

Publication number: PT88365A
Authority: PT; Portugal
Prior art keywords: kinolino; phenyl; substituted; preparation; carboxylic acid
Prior art date: 1987-08-31

Application number

PT88365A

Other languages

English (en)

Other versions

PT88365B (pt

Inventor

Leslie H Sutherland

Adolph E Sloboda

Ralph Grassing Child

John F Poletto

Dennis W Powell

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-08-31

Filing date

1988-08-29

Publication date

1989-06-30

1988-08-29 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1989-06-30 Publication of PT88365A publication Critical patent/PT88365A/pt

1995-03-31 Publication of PT88365B publication Critical patent/PT88365B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Quinoline Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

PT88365A 1987-08-31 1988-08-29 Processo para a preparacao de acidos 2-fenil-4-quinolino-carboxilicos substituidos PT88365B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/090,996 US4847381A (en)	1987-08-31	1987-08-31	2-Phenyl-4-quinoline carboxylic acids

Publications (2)

Publication Number	Publication Date
PT88365A true PT88365A (pt)	1989-06-30
PT88365B PT88365B (pt)	1995-03-31

Family

ID=22225261

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT88365A PT88365B (pt)	1987-08-31	1988-08-29	Processo para a preparacao de acidos 2-fenil-4-quinolino-carboxilicos substituidos

Country Status (24)

Country	Link
US (1)	US4847381A (pt)
EP (1)	EP0305952B1 (pt)
JP (1)	JP2760379B2 (pt)
KR (1)	KR970005909B1 (pt)
AR (1)	AR245698A1 (pt)
AT (1)	ATE90079T1 (pt)
AU (1)	AU613661B2 (pt)
CA (1)	CA1333606C (pt)
CS (1)	CS274434B2 (pt)
DD (1)	DD282225A5 (pt)
DE (1)	DE3881456T2 (pt)
DK (1)	DK169473B1 (pt)
ES (1)	ES2058191T3 (pt)
FI (1)	FI92692C (pt)
GR (1)	GR3008033T3 (pt)
HU (1)	HU202498B (pt)
IE (1)	IE65148B1 (pt)
IL (1)	IL87457A (pt)
NO (1)	NO174961C (pt)
NZ (1)	NZ225924A (pt)
PH (1)	PH26258A (pt)
PL (1)	PL156232B1 (pt)
PT (1)	PT88365B (pt)
ZA (1)	ZA886443B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4968701A (en) *	1988-04-26	1990-11-06	E. I. Du Pont De Nemours And Company	4-Quinoline carboxylic acid derivatives useful as immunosuppressive agents
US4918077A (en) *	1989-01-25	1990-04-17	E. I. Du Pont De Nemours & Co., Inc.	3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents
US5204329A (en) *	1990-06-11	1993-04-20	Du Pont Merck Pharmaceutical Company	Treatment of organ transplantation rejection
US5135934A (en) *	1990-07-06	1992-08-04	Du Pont Merck Pharmaceutical Company	3-phenyl-5,6-dihydrobenz(c) acridine-7-carboxylic acids and related compounds as immunosuppressive agents
US5409886A (en) *	1993-02-18	1995-04-25	Mitsui Toatsu Chemicals, Incorporated	3-pyrroline-2-one derivatives and herbicidal compositions containing same
US5428040A (en) *	1993-08-31	1995-06-27	The Du Pont Merck Pharmaceutical Company	Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents
US5578609A (en) *	1994-03-25	1996-11-26	The Dupont Merck Pharmaceutical Company	2-carbocyclic and 2-heterocyclic quinoline-4-carboxylic acids and salts thereof useful as immunosuppressive agents
ID18663A (id) *	1996-04-12	1998-04-30	Novartis Ag	Komposisi farmasi berlapis enterik
US6207679B1 (en)	1997-06-19	2001-03-27	Sepracor, Inc.	Antimicrobial agents uses and compositions related thereto
US6376670B1 (en)	1997-06-19	2002-04-23	Sepracor Inc.	Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6103905A (en) *	1997-06-19	2000-08-15	Sepracor, Inc.	Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6172084B1 (en)	1997-06-19	2001-01-09	Sepracor, Inc.	Quinoline-indole antimicrobial agents, uses and compositions related thereto
WO1999038846A1 (en) *	1998-01-30	1999-08-05	Procept, Inc.	Immunosuppressive agents
SE9901366D0 (sv) *	1999-04-16	1999-04-16	Pharmacia & Upjohn Ab	Injector device and method for its operation
US20020121638A1 (en) *	2000-06-30	2002-09-05	Vladimir Grushin	Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such compounds
WO2009016812A1 (ja) *	2007-07-27	2009-02-05	Kowa Company, Ltd.	２－フェニルキノリン－４－カルボン酸誘導体を有効成分とする貧血の予防及び／又は治療剤
US20160287549A1 (en)	2013-11-22	2016-10-06	Genzyme Corporation	Novel methods for treating neurodegenerative diseases

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2776290A (en) *		1957-01-01		Hydroxy cevchoninates and carboxylic
US2008923A (en) *	1931-07-09	1935-07-23	Graham Patmore L	Cinchoninic acid salts of piperazines
US2077903A (en) *	1933-12-15	1937-04-20	Gen Aniline Works Inc	Process of preparing 3-amino-quinolines
US2486440A (en) *	1946-01-10	1949-11-01	Gen Aniline & Film Corp	Production of phenazonium dyestuff images
BE502610A (pt) *	1950-04-18
US2888346A (en) *	1955-08-22	1959-05-26	Gen Aniline & Film Corp	Ultra-violet absorbing compounds
DE1049701B (pt) *	1957-02-21
FR6592M (pt) *	1967-10-31	1968-12-30
BE794945A (fr) *	1972-02-04	1973-08-02	Sandoz Sa	Application de derives de la quinoleine pour stabiliser des matieres organiques contre les effets de la lumiere ultraviolette
US4009020A (en) *	1975-05-06	1977-02-22	Amchem Products, Inc.	Method of regulating plant growth
SU1109402A1 (ru) *	1982-10-12	1984-08-23	Предприятие П/Я Р-6496	Способ получени производных 2-(хинолил-4)-5-арилоксазола
ZA845594B (en) *	1983-07-22	1986-03-26	Du Pont	Phenylquinolinecarboxylic acids and derivatives as antitumor agents
US4680299A (en) *	1984-04-30	1987-07-14	E.I. Du Pont De Nemours And Company	2-phenyl-4-quinolinecarboxylic acids and pharmaceutical compositions thereof

1987
- 1987-08-31 US US07/090,996 patent/US4847381A/en not_active Expired - Lifetime
1988
- 1988-08-15 IL IL8745788A patent/IL87457A/en not_active IP Right Cessation
- 1988-08-24 NZ NZ225924A patent/NZ225924A/en unknown
- 1988-08-29 PH PH37473A patent/PH26258A/en unknown
- 1988-08-29 EP EP88114061A patent/EP0305952B1/en not_active Expired - Lifetime
- 1988-08-29 AT AT88114061T patent/ATE90079T1/de active
- 1988-08-29 PT PT88365A patent/PT88365B/pt not_active IP Right Cessation
- 1988-08-29 DE DE88114061T patent/DE3881456T2/de not_active Expired - Fee Related
- 1988-08-29 ES ES88114061T patent/ES2058191T3/es not_active Expired - Lifetime
- 1988-08-29 CA CA000575951A patent/CA1333606C/en not_active Expired - Fee Related
- 1988-08-30 KR KR1019880011111A patent/KR970005909B1/ko not_active Expired - Fee Related
- 1988-08-30 FI FI883997A patent/FI92692C/fi not_active IP Right Cessation
- 1988-08-30 IE IE262888A patent/IE65148B1/en not_active IP Right Cessation
- 1988-08-30 AU AU21678/88A patent/AU613661B2/en not_active Ceased
- 1988-08-30 ZA ZA886443A patent/ZA886443B/xx unknown
- 1988-08-30 DK DK482688A patent/DK169473B1/da not_active IP Right Cessation
- 1988-08-30 NO NO883865A patent/NO174961C/no not_active IP Right Cessation
- 1988-08-30 AR AR88311798A patent/AR245698A1/es active
- 1988-08-30 HU HU884489A patent/HU202498B/hu not_active IP Right Cessation
- 1988-08-30 JP JP63213853A patent/JP2760379B2/ja not_active Expired - Lifetime
- 1988-08-31 DD DD88319347A patent/DD282225A5/de not_active IP Right Cessation
- 1988-08-31 CS CS587588A patent/CS274434B2/cs unknown
- 1988-08-31 PL PL1988274471A patent/PL156232B1/pl unknown
1993
- 1993-06-03 GR GR930400370T patent/GR3008033T3/el unknown

Also Published As

Publication number	Publication date
NO883865L (no)	1989-03-01
ATE90079T1 (de)	1993-06-15
HU202498B (en)	1991-03-28
GR3008033T3 (pt)	1993-09-30
NO174961B (no)	1994-05-02
NZ225924A (en)	1991-07-26
AU613661B2 (en)	1991-08-08
NO174961C (no)	1994-08-10
AU2167888A (en)	1989-03-02
FI92692B (fi)	1994-09-15
EP0305952A1 (en)	1989-03-08
IL87457A0 (en)	1989-01-31
HUT48597A (en)	1989-06-28
JP2760379B2 (ja)	1998-05-28
CS587588A2 (en)	1990-06-13
DE3881456D1 (de)	1993-07-08
FI883997L (fi)	1989-03-01
PT88365B (pt)	1995-03-31
KR890003703A (ko)	1989-04-17
CS274434B2 (en)	1991-04-11
FI883997A0 (fi)	1988-08-30
ES2058191T3 (es)	1994-11-01
FI92692C (fi)	1994-12-27
PL274471A1 (en)	1989-05-02
IE882628L (en)	1989-02-28
IE65148B1 (en)	1995-10-04
ZA886443B (en)	1989-04-26
US4847381A (en)	1989-07-11
NO883865D0 (no)	1988-08-30
DK169473B1 (da)	1994-11-07
IL87457A (en)	1994-08-26
DD282225A5 (de)	1990-09-05
DK482688D0 (da)	1988-08-30
DE3881456T2 (de)	1994-01-13
KR970005909B1 (ko)	1997-04-22
AR245698A1 (es)	1994-02-28
PL156232B1 (en)	1992-02-28
JPH01110673A (ja)	1989-04-27
CA1333606C (en)	1994-12-20
DK482688A (da)	1989-03-01
PH26258A (en)	1992-04-01
EP0305952B1 (en)	1993-06-02

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PT88044A (pt)	1989-06-30	Processo para a preparacao de acidos tetra-hidrocarbazole-1-alcanoicos
PT83179B (pt)	1989-03-30	Processo para a preparacao de carbinois aril-piperidinicos
PT89264A (pt)	1989-12-29	Processo para a preparacao de compostos azabiciclicos
PT82769B (pt)	1988-04-21	Processo para a preparacao de derivados de acidos tiazolidino-4(s)-caboxilicos
BR8804284A (pt)	1989-03-21	Processo para a preparacao de acidos etercarboxilicos
PT88365A (pt)	1989-06-30	Processo para a preparacao de acidos 2-fenil-4-quinolino-carboxilicos substituidos
PT83180B (pt)	1989-03-30	Processo para a preparacao de esteres aril-piperidinicos
BR8801269A (pt)	1988-10-25	Processo para a preparacao de um composto de ciano-imidazol
PT83332A (pt)	1986-10-01	Processo aperfeicoado para a preparacao de acido tetrafluorobenzoico
PT88180A (pt)	1989-06-30	Processo para a preparacao de derivados alquilaminoalcoxifenilo
PT89039A (pt)	1988-12-01	Processo para a preparacao de l-ramnose
BR8803678A (pt)	1989-02-14	Processo para a preparacao de polieteramidas
PT88078A (pt)	1989-06-30	Processo para a preparacao de acidos quinolonocarboxilicos
PT82245B (pt)	1988-02-17	Processo para a preparacao de 2-amino-6-cloropurina
PT88924A (pt)	1988-12-01	Processo para a preparacao de derivados de ginkgolidos
PT88990A (pt)	1989-11-30	Processo para a preparacao de novos acidos aza-cicloalquil-alcano-difosfonicos
BR8806351A (pt)	1989-08-22	Processo para a preparacao de fenil-ureias
BR8806834A (pt)	1989-08-29	Processo para a preparacao de resorcinol
PT89237A (pt)	1989-12-29	Processo para a preparacao de compostos beta-lactamicos
BR8602094A (pt)	1987-01-06	Processo para a preparacao de benzotiazolsulfenamidas
PT83154B (pt)	1989-03-30	Processo para a preparacao de quinolizino-sulfonamidas
PT89291A (pt)	1989-12-29	Processo para a preparacao de compostos de acidos 1-benzo-oxacicloalquil-piridinocarboxilicos hidrogenados

Legal Events

Date	Code	Title	Description
1995-03-31	FG3A	Patent granted, date of granting	Effective date: 19940919
2002-07-31	MM3A	Annulment or lapse	Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20020331

Date

Code

Title

Description

1995-03-31

FG3A

Patent granted, date of granting

Effective date: 19940919

2002-07-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20020331