FI883603A7 - Menetelmä terapeuttisesti käyttökelpoisten 1,4-dihydropyridiinijohdannaisten valmistamiseksi - Google Patents
Menetelmä terapeuttisesti käyttökelpoisten 1,4-dihydropyridiinijohdannaisten valmistamiseksiInfo
- Publication number
- FI883603A7 FI883603A7 FI883603A FI883603A FI883603A7 FI 883603 A7 FI883603 A7 FI 883603A7 FI 883603 A FI883603 A FI 883603A FI 883603 A FI883603 A FI 883603A FI 883603 A7 FI883603 A7 FI 883603A7
- Authority
- FI
- Finland
- Prior art keywords
- therapeutically useful
- dihydropyridine derivatives
- preparing therapeutically
- preparing
- dihydropyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP87401799A EP0302980B1 (fr) | 1987-08-03 | 1987-08-03 | 1,4-Dihydropyridines, leur procédé de préparation et leur application comme médicaments |
| EP87401799 | 1987-08-03 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI883603A0 FI883603A0 (fi) | 1988-08-01 |
| FI883603A7 true FI883603A7 (fi) | 1989-02-04 |
| FI91406B FI91406B (fi) | 1994-03-15 |
| FI91406C FI91406C (fi) | 1994-06-27 |
Family
ID=8198243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI883603A FI91406C (fi) | 1987-08-03 | 1988-08-01 | Menetelmä terapeuttisesti käyttökelpoisten 1,4-dihydropyridiinijohdannaisten valmistamiseksi |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US4952592A (fi) |
| EP (1) | EP0302980B1 (fi) |
| JP (1) | JPH0733383B2 (fi) |
| KR (1) | KR960001724B1 (fi) |
| CN (1) | CN1038587C (fi) |
| AT (1) | ATE61588T1 (fi) |
| BE (1) | BE1001055A4 (fi) |
| CA (2) | CA1306261C (fi) |
| CH (1) | CH675999A5 (fi) |
| CZ (1) | CZ282077B6 (fi) |
| DD (1) | DD282008A5 (fi) |
| DE (2) | DE3768658D1 (fi) |
| DK (1) | DK430288A (fi) |
| ES (1) | ES2007543A6 (fi) |
| FI (1) | FI91406C (fi) |
| GB (1) | GB2208861B (fi) |
| GR (2) | GR880100507A (fi) |
| HU (1) | HU204523B (fi) |
| IE (1) | IE60358B1 (fi) |
| IL (1) | IL87321A (fi) |
| IN (1) | IN167550B (fi) |
| IS (1) | IS1549B (fi) |
| IT (1) | IT1235013B (fi) |
| LU (1) | LU87297A1 (fi) |
| MA (1) | MA21344A1 (fi) |
| NO (1) | NO170934C (fi) |
| NZ (1) | NZ225661A (fi) |
| PH (1) | PH25645A (fi) |
| PT (1) | PT88173B (fi) |
| RU (1) | RU2036922C1 (fi) |
| SK (1) | SK541388A3 (fi) |
| TN (1) | TNSN88081A1 (fi) |
| YU (1) | YU46547B (fi) |
| ZA (1) | ZA885684B (fi) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5242933A (en) * | 1990-07-10 | 1993-09-07 | Adir Et Compagnie | Piperidine, tetrahydropyridine and pyrrolidine compounds |
| EP0854721B1 (en) * | 1995-08-02 | 2001-10-24 | Smithkline Beecham Corporation | Endothelin receptor antagonists |
| RU2168987C2 (ru) * | 1997-04-15 | 2001-06-20 | Санкт-Петербургская Государственная Химико-Фармацевтическая Академия | Гипотензивное средство |
| RU2155036C2 (ru) * | 1998-11-11 | 2000-08-27 | Азад Зияд Оглы Абышев | Средство для лечения ишемической болезни сердца |
| IT1304513B1 (it) * | 1998-12-30 | 2001-03-19 | Endura Spa | Processo per la sintesi di 5-(alfa-idrossialchil)benzo(1,3)diossoli. |
| BR0109991A (pt) * | 2000-04-11 | 2003-05-27 | Sankyo Co | Composição farmacêutica |
| RU2187303C2 (ru) * | 2000-10-12 | 2002-08-20 | Азад Зияд Оглы Абышев | Способ получения таблеток диуманкала - forte по 0,01 г |
| BR0313593A (pt) | 2002-08-19 | 2005-07-12 | Pfizer Prod Inc | Terapia de combinação para doenças hiperproliferativas |
| KR20070054644A (ko) * | 2004-07-26 | 2007-05-29 | 액테리온 파마슈티칼 리미티드 | 미립자 제형으로 흡입된 일로프로스트에 의한 폐고혈압의치료 |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| EP2111863B1 (en) | 2005-10-26 | 2012-03-28 | Asahi Kasei Pharma Corporation | Fasudil in combination with bosentan for the treament of pulmonary arterial hypertension |
| EP2351569B1 (en) | 2005-10-26 | 2012-08-22 | Asahi Kasei Pharma Corporation | Fasudil in combination therapies for the treatment of pulmonary arterial hypertension |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| TW200736245A (en) * | 2005-11-29 | 2007-10-01 | Sankyo Co | Acid addition salts of optically active dihydropyridine derivatives |
| TW200806648A (en) * | 2005-11-29 | 2008-02-01 | Sankyo Co | Acid addition salts of dihydropyridine derivatives |
| US7919506B2 (en) | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
| ATE547394T1 (de) | 2006-12-01 | 2012-03-15 | Bristol Myers Squibb Co | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen |
| WO2012037665A1 (en) | 2010-09-24 | 2012-03-29 | Oral Delivery Technology Ltd. | Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions |
| CA2909442A1 (en) | 2013-04-17 | 2014-10-23 | Pfizer Inc. | N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| HUE069590T2 (hu) | 2019-01-18 | 2025-03-28 | Astrazeneca Ab | PCSK9-gátló 6'-[[(1s,3s)-3-[[5-(difluormetoxi)-2-pirimidinil]amino]ciklopentil]amino][1(2h ),3'-bipiridin]-2-on és alkalmazására szolgáló eljárások |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3441648A (en) * | 1967-02-07 | 1969-04-29 | Smithkline Corp | Compositions and methods for lowering blood pressure with 1,4-dihydropyridines |
| US4031104A (en) * | 1972-04-18 | 1977-06-21 | Bayer Aktiengesellschaft | 1,4-Dihydropyridine carboxylic acid esters |
| JPS5978186A (ja) * | 1982-10-27 | 1984-05-04 | Yoshitomi Pharmaceut Ind Ltd | 1,4−ジヒドロピリジン−3,5−ジカルボン酸エステル誘導体 |
| ES531033A0 (es) * | 1984-03-27 | 1985-09-01 | Inst Investigacion Desarrollo | Un procedimiento para la preparacion de nuevas 1,4-dihidropirinas-4-(polioxialquilfenil)-sustituidas |
| IE57810B1 (en) * | 1984-03-27 | 1993-04-21 | Delagrange Lab | 1,4-dihydropyridine derivatives,their preparation and their use |
| JPH068294B2 (ja) * | 1985-02-26 | 1994-02-02 | 富山化学工業株式会社 | 新規な1,4−ジヒドロピリジン誘導体およびその塩 |
| EP0174131A3 (en) * | 1984-09-01 | 1989-06-07 | FISONS plc | Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them |
| JPH01207267A (ja) * | 1987-03-05 | 1989-08-21 | Yamanouchi Pharmaceut Co Ltd | ピリジン誘導体及び該化合物を含有する肝疾患治療剤 |
-
1987
- 1987-08-03 DE DE8787401799T patent/DE3768658D1/de not_active Expired - Lifetime
- 1987-08-03 AT AT87401799T patent/ATE61588T1/de active
- 1987-08-03 EP EP87401799A patent/EP0302980B1/fr not_active Expired - Lifetime
-
1988
- 1988-07-27 LU LU87297A patent/LU87297A1/fr unknown
- 1988-07-29 YU YU147088A patent/YU46547B/sh unknown
- 1988-07-29 DE DE3825962A patent/DE3825962A1/de not_active Withdrawn
- 1988-07-29 CA CA000573422A patent/CA1306261C/fr not_active Expired - Lifetime
- 1988-08-01 MA MA21587A patent/MA21344A1/fr unknown
- 1988-08-01 JP JP63192591A patent/JPH0733383B2/ja not_active Expired - Lifetime
- 1988-08-01 FI FI883603A patent/FI91406C/fi not_active IP Right Cessation
- 1988-08-01 DD DD88318537A patent/DD282008A5/de not_active IP Right Cessation
- 1988-08-01 NO NO883406A patent/NO170934C/no unknown
- 1988-08-02 IS IS3378A patent/IS1549B/is unknown
- 1988-08-02 GB GB8818356A patent/GB2208861B/en not_active Expired - Lifetime
- 1988-08-02 SK SK5413-88A patent/SK541388A3/sk unknown
- 1988-08-02 GR GR880100507A patent/GR880100507A/el unknown
- 1988-08-02 CZ CS885413A patent/CZ282077B6/cs not_active IP Right Cessation
- 1988-08-02 ES ES8802413A patent/ES2007543A6/es not_active Expired
- 1988-08-02 TN TNTNSN88081A patent/TNSN88081A1/fr unknown
- 1988-08-02 BE BE8800893A patent/BE1001055A4/fr not_active IP Right Cessation
- 1988-08-02 US US07/227,373 patent/US4952592A/en not_active Expired - Fee Related
- 1988-08-02 NZ NZ225661A patent/NZ225661A/xx unknown
- 1988-08-02 DK DK430288A patent/DK430288A/da not_active Application Discontinuation
- 1988-08-02 KR KR1019880009867A patent/KR960001724B1/ko not_active Expired - Fee Related
- 1988-08-02 PT PT88173A patent/PT88173B/pt not_active IP Right Cessation
- 1988-08-02 CN CN88106537A patent/CN1038587C/zh not_active Expired - Fee Related
- 1988-08-02 HU HU884065A patent/HU204523B/hu not_active IP Right Cessation
- 1988-08-02 IL IL87321A patent/IL87321A/xx not_active IP Right Cessation
- 1988-08-02 IE IE236488A patent/IE60358B1/en not_active IP Right Cessation
- 1988-08-02 IT IT8848259A patent/IT1235013B/it active
- 1988-08-02 CH CH2922/88A patent/CH675999A5/fr not_active IP Right Cessation
- 1988-08-03 ZA ZA885684A patent/ZA885684B/xx unknown
- 1988-08-03 PH PH37337A patent/PH25645A/en unknown
- 1988-08-03 IN IN556/MAS/88A patent/IN167550B/en unknown
-
1990
- 1990-08-28 CA CA000615848A patent/CA1306262C/fr not_active Expired - Lifetime
-
1991
- 1991-05-22 GR GR91400660T patent/GR3001984T3/el unknown
-
1992
- 1992-03-31 RU SU925011204A patent/RU2036922C1/ru active
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| PC | Transfer of assignment of patent |
Owner name: ALMIRALL-PRODESFARMA S.A. |
|
| TC | Name/ company changed in patent |
Owner name: ALMIRALL-PRODESFARMA S.A. |
|
| MM | Patent lapsed |
Owner name: ALMIRALL-PRODESFARMA S.A. |