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FI882059L - Menetelmä vierasproteiinien valmistamiseksi Streptomycessoluissa - Google Patents

Menetelmä vierasproteiinien valmistamiseksi Streptomycessoluissa Download PDF

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Publication number
FI882059L
FI882059L FI882059A FI882059A FI882059L FI 882059 L FI882059 L FI 882059L FI 882059 A FI882059 A FI 882059A FI 882059 A FI882059 A FI 882059A FI 882059 L FI882059 L FI 882059L
Authority
FI
Finland
Prior art keywords
foreign proteins
streptomyces cells
producing foreign
producing
streptomyces
Prior art date
Application number
FI882059A
Other languages
English (en)
Swedish (sv)
Other versions
FI882059A0 (fi
FI97549B (fi
FI97549C (fi
Inventor
Klaus-Peter Koller
Guenther Johannes Riess
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI882059A0 publication Critical patent/FI882059A0/fi
Publication of FI882059L publication Critical patent/FI882059L/fi
Publication of FI97549B publication Critical patent/FI97549B/fi
Application granted granted Critical
Publication of FI97549C publication Critical patent/FI97549C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
FI882059A 1987-05-05 1988-05-03 Menetelmä vierasproteiinien valmistamiseksi Streptomycessoluissa FI97549C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3714866 1987-05-05
DE19873714866 DE3714866A1 (de) 1987-05-05 1987-05-05 Verfahren zur herstellung von fremdproteinen in streptomyceten

Publications (4)

Publication Number Publication Date
FI882059A0 FI882059A0 (fi) 1988-05-03
FI882059L true FI882059L (fi) 1988-11-06
FI97549B FI97549B (fi) 1996-09-30
FI97549C FI97549C (fi) 1997-01-10

Family

ID=6326841

Family Applications (1)

Application Number Title Priority Date Filing Date
FI882059A FI97549C (fi) 1987-05-05 1988-05-03 Menetelmä vierasproteiinien valmistamiseksi Streptomycessoluissa

Country Status (19)

Country Link
EP (1) EP0289936B1 (fi)
JP (1) JP2671260B2 (fi)
KR (1) KR970001235B1 (fi)
CN (1) CN1029989C (fi)
AR (1) AR241658A1 (fi)
AT (1) ATE94905T1 (fi)
AU (1) AU612144B2 (fi)
CA (1) CA1338338C (fi)
DE (2) DE3714866A1 (fi)
DK (1) DK175525B1 (fi)
ES (1) ES2045004T3 (fi)
FI (1) FI97549C (fi)
HU (1) HU204094B (fi)
IE (1) IE62522B1 (fi)
IL (1) IL86277A0 (fi)
NO (1) NO178036C (fi)
NZ (1) NZ224464A (fi)
PT (1) PT87400B (fi)
ZA (1) ZA883168B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4012818A1 (de) 1990-04-21 1991-10-24 Hoechst Ag Verfahren zur herstellung von fremdproteinen in streptomyceten
US5426036A (en) * 1987-05-05 1995-06-20 Hoechst Aktiengesellschaft Processes for the preparation of foreign proteins in streptomycetes
ATE132531T1 (de) * 1988-11-03 1996-01-15 Hoechst Ag Verfahren zur herstellung eines insulin- vorprodukts in streptomyceten
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
DE3936876A1 (de) * 1989-11-06 1991-05-23 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3331860A1 (de) * 1983-09-03 1985-03-21 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von tendamistat
DE3418274A1 (de) * 1984-05-17 1985-11-21 Hoechst Ag, 6230 Frankfurt Signalpeptid fuer die exkretion von peptiden in streptomyceten
EP0196056B1 (en) * 1985-03-28 1991-05-22 Chiron Corporation Improved expression using fused genes providing for protein product
DE3707150A1 (de) * 1987-03-06 1988-09-15 Hoechst Ag Tendamistat-derivate
ATE132531T1 (de) * 1988-11-03 1996-01-15 Hoechst Ag Verfahren zur herstellung eines insulin- vorprodukts in streptomyceten

Also Published As

Publication number Publication date
IE62522B1 (en) 1995-02-08
AU612144B2 (en) 1991-07-04
CN1029989C (zh) 1995-10-11
DK175525B1 (da) 2004-11-22
IL86277A0 (en) 1988-11-15
KR970001235B1 (ko) 1997-02-04
ATE94905T1 (de) 1993-10-15
PT87400A (pt) 1989-05-31
AR241658A1 (es) 1992-10-30
NZ224464A (en) 1990-02-26
DE3714866A1 (de) 1988-11-24
CN88102568A (zh) 1988-11-23
DK241688A (da) 1988-11-06
EP0289936B1 (de) 1993-09-22
FI882059A0 (fi) 1988-05-03
PT87400B (pt) 1992-09-30
KR880014102A (ko) 1988-12-22
JPS63301793A (ja) 1988-12-08
DE3884261D1 (de) 1993-10-28
FI97549B (fi) 1996-09-30
IE881338L (en) 1988-11-05
NO178036B (no) 1995-10-02
JP2671260B2 (ja) 1997-10-29
EP0289936A3 (en) 1989-11-23
EP0289936A2 (de) 1988-11-09
AU1555988A (en) 1988-11-10
CA1338338C (en) 1996-05-21
HU204094B (en) 1991-11-28
NO178036C (no) 1996-01-10
NO881942D0 (no) 1988-05-04
ZA883168B (en) 1989-11-29
DK241688D0 (da) 1988-05-04
HUT46941A (en) 1988-12-28
ES2045004T3 (es) 1994-01-16
FI97549C (fi) 1997-01-10
NO881942L (no) 1988-11-07

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: HOECHST AKTIENGESELLSCHAFT