ES8604548A1 - Procedimiento para preparar nuevos derivados de acidos feni-laceticos - Google Patents
Procedimiento para preparar nuevos derivados de acidos feni-laceticosInfo
- Publication number
- ES8604548A1 ES8604548A1 ES545883A ES545883A ES8604548A1 ES 8604548 A1 ES8604548 A1 ES 8604548A1 ES 545883 A ES545883 A ES 545883A ES 545883 A ES545883 A ES 545883A ES 8604548 A1 ES8604548 A1 ES 8604548A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- group
- phenylacetic
- carbon atoms
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical class OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 3
- YZCKVEUIGOORGS-UHFFFAOYSA-N Hydrogen atom Chemical compound [H] YZCKVEUIGOORGS-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Glass Compositions (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
- Lubricants (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE ACIDOS FENILACETICOS, DE FORMULA GENERAL (I), EN LA QUE R1 SIGNIFICA UN GRUPO ALQUILENIMINO CON 4 A 6 ATOMOS DE CARBONO, NO RAMIFICADO; R2 SIGNIFICA UN ATOMO DE HIDROGENO O HALOGENO; R3 SIGNIFICA UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO DE 1 A 7 ATOMOS DE CARBONO; R4 SIGNIFICA UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO DE 1 A 3 ATOMOS DE CARBONO; Y W SIGNIFICA UN GRUPO METILO O FORMILO, Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. CONSISTE EN REDUCIR UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE R1, R2, R4 Y W TIENEN LOS SIGNIFICADOS YA MENCIONADOS; E Y SIGNIFICA UN GRUPO DE FORMULA (III). DE APLICACION EN EL TRATAMIENTO DE LA DIABETES MELLITUS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833347565 DE3347565A1 (de) | 1983-12-30 | 1983-12-30 | Neue phenylessigsaeurederivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE19853522604 DE3522604A1 (de) | 1983-12-30 | 1985-06-25 | Neue feste formen von 2-(gamma)thoxy-4-(n-(1-(2-piperidino-phenyl)-3-methyl-1-butyl)-aminocarbonylmethyl)-benzoesaeure, diese formen enthaltende arzneimittel und verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8604548A1 true ES8604548A1 (es) | 1986-02-01 |
| ES545883A0 ES545883A0 (es) | 1986-02-01 |
Family
ID=37847099
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES539078A Expired ES8605500A1 (es) | 1983-12-30 | 1984-12-27 | Procedimiento para preparar derivados de acidos fenilaceticos. |
| ES545881A Expired ES8604546A1 (es) | 1983-12-30 | 1985-08-05 | Procedimiento para preparar nuevos derivados de acidos feni-laceticos |
| ES545879A Expired ES8604544A1 (es) | 1983-12-30 | 1985-08-05 | Procedimiento para preparar nuevos derivados de acidos feni-laceticos |
| ES545883A Expired ES8604548A1 (es) | 1983-12-30 | 1985-08-05 | Procedimiento para preparar nuevos derivados de acidos feni-laceticos |
| ES545882A Expired ES8604547A1 (es) | 1983-12-30 | 1985-08-05 | Procedimiento para preparar nuevos derivados de acidos feni-laceticos |
| ES545880A Expired ES8604545A1 (es) | 1983-12-30 | 1985-08-05 | Procedimiento para preparar nuevos derivados de acidos feni-laceticos |
| ES556495A Expired ES8802145A1 (es) | 1983-12-30 | 1986-06-24 | Procedimiento para preparar dos nuevas formas solidas de acido 2-etoxi-4-(n-(1-(2-piperidino-fenil)-3-metil-1-butil)-aminocarbonilmetil)-benzoico |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES539078A Expired ES8605500A1 (es) | 1983-12-30 | 1984-12-27 | Procedimiento para preparar derivados de acidos fenilaceticos. |
| ES545881A Expired ES8604546A1 (es) | 1983-12-30 | 1985-08-05 | Procedimiento para preparar nuevos derivados de acidos feni-laceticos |
| ES545879A Expired ES8604544A1 (es) | 1983-12-30 | 1985-08-05 | Procedimiento para preparar nuevos derivados de acidos feni-laceticos |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES545882A Expired ES8604547A1 (es) | 1983-12-30 | 1985-08-05 | Procedimiento para preparar nuevos derivados de acidos feni-laceticos |
| ES545880A Expired ES8604545A1 (es) | 1983-12-30 | 1985-08-05 | Procedimiento para preparar nuevos derivados de acidos feni-laceticos |
| ES556495A Expired ES8802145A1 (es) | 1983-12-30 | 1986-06-24 | Procedimiento para preparar dos nuevas formas solidas de acido 2-etoxi-4-(n-(1-(2-piperidino-fenil)-3-metil-1-butil)-aminocarbonilmetil)-benzoico |
Country Status (26)
| Country | Link |
|---|---|
| EP (2) | EP0147850B1 (es) |
| JP (2) | JPH0623200B2 (es) |
| KR (1) | KR900005320B1 (es) |
| AT (1) | ATE44027T1 (es) |
| AU (2) | AU577815B2 (es) |
| BG (1) | BG61519B2 (es) |
| CA (2) | CA1225398A (es) |
| CS (1) | CS409791A3 (es) |
| DD (1) | DD231348A5 (es) |
| DE (4) | DE3347565A1 (es) |
| DK (2) | DK167439B1 (es) |
| ES (7) | ES8605500A1 (es) |
| FI (2) | FI80447C (es) |
| GR (2) | GR82614B (es) |
| HK (1) | HK87492A (es) |
| HU (1) | HU194548B (es) |
| IE (1) | IE57700B1 (es) |
| IL (2) | IL73963A (es) |
| LU (1) | LU90301I2 (es) |
| MX (1) | MX9202772A (es) |
| NL (1) | NL980034I1 (es) |
| NO (3) | NO162819C (es) |
| NZ (2) | NZ210657A (es) |
| PT (2) | PT79772B (es) |
| SG (1) | SG55492G (es) |
| ZA (2) | ZA8410103B (es) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3523466A1 (de) * | 1985-07-01 | 1987-01-08 | Thomae Gmbh Dr K | Neue phenylessigsaeurederivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE3347565A1 (de) * | 1983-12-30 | 1985-07-11 | Thomae Gmbh Dr K | Neue phenylessigsaeurederivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| SG43036A1 (en) * | 1991-06-21 | 1997-10-17 | Thomae Gmbh Dr K | (S) (+) -2-ethoxy-4-[N-[1-(2-piperidino-phenyl)-3-methyl- 1-buthyl]aminocarbony methyl] - benzoic a cid |
| EP0965591B1 (de) * | 1991-06-21 | 2002-09-04 | Boehringer Ingelheim Pharma KG | Verfahren zur Herstellung von (S)-3-Methyl-1-(2-piperidino-phenyl)-1-butylamin |
| FR2763590B1 (fr) * | 1997-05-22 | 2000-03-24 | Synthelabo | Derives d'acides[[[(arylmethyl)amino]carbonyl] alkyl]- aromatiques, leur preparation et leur application en therapeutique |
| EP1741445B1 (en) | 2000-01-21 | 2013-08-14 | Novartis AG | Combinations comprising dipeptidylpeptidase-IV inhibitors and antidiabetic agents |
| US20040102477A1 (en) * | 2002-08-23 | 2004-05-27 | Dr. Reddy's Laboratories Limited | Polymorphic forms of (S)-Repaglinide and the processes for preparation thereof |
| US7915421B2 (en) | 2003-05-14 | 2011-03-29 | Cilag Ltd. | Method for preparing phenyl acetic acid derivatives |
| AU2003237595A1 (en) * | 2003-05-26 | 2004-12-13 | Biocon Limited | Process for the preparation of s(+)-2-ethoxy-4-(n-{1-(2-piperidinophelyl)-3-methyl-1- butyl} aminocarbonylmethyl)benzoic acid derivatives |
| WO2004108673A2 (en) * | 2003-06-09 | 2004-12-16 | Boehringer Ingelheim International Gmbh | Inhibitors of papilloma virus |
| FR2875805B1 (fr) * | 2004-09-27 | 2006-12-29 | Genfit S A | Composes derives de n-(benzyl) phenylacetamide substitues, preparation et utilisations |
| CN1305863C (zh) * | 2004-12-27 | 2007-03-21 | 浙江大学 | (s)－异丙基－(2－哌啶)苯基－甲基胺的合成方法 |
| GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
| EA015735B1 (ru) | 2005-09-14 | 2011-10-31 | Такеда Фармасьютикал Компани Лимитед | Фармацевтические композиции на основе 2-[[6-[(3r)-3-амино-1-пиперидинил]-3,4-дигидро-3-метил-2,4-диоксо-1(2н)-пиримидинил]метил]бензонитрила |
| EP2177221A1 (en) | 2008-10-20 | 2010-04-21 | Krka Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of substantially optically pure Repaglinide and precursors thereof |
| EA201101621A1 (ru) | 2009-05-15 | 2012-05-30 | Новартис Аг | Производные бензоксазолона в качестве ингибиторов альдостеронсинтазы |
| SG175925A1 (en) | 2009-05-15 | 2011-12-29 | Novartis Ag | Aryl pyridine as aldosterone synthase inhibitors |
| SI2435409T1 (sl) | 2009-05-28 | 2014-12-31 | Novartis Ag | Substituirani aminopropionski derivati kot inhibitorji neprilizina |
| EA201101672A1 (ru) | 2009-05-28 | 2012-06-29 | Новартис Аг | Замещенные производные аминомасляной кислоты в качестве ингибиторов неприлизина |
| WO2011041293A1 (en) | 2009-09-30 | 2011-04-07 | Takeda Pharmaceutical Company Limited | Pyrazolo [1, 5-a] pyrimidine derivatives as apoptosis signal-regulating kinase 1 inhibitors |
| WO2011061168A1 (en) | 2009-11-17 | 2011-05-26 | Novartis Ag | Aryl-pyridine derivatives as aldosterone synthase inhibitors |
| JO2967B1 (en) | 2009-11-20 | 2016-03-15 | نوفارتس ايه جي | Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors |
| US8575160B2 (en) | 2009-11-30 | 2013-11-05 | Novartis Ag | Imidazole derivatives as aldosterone synthase inhibitors |
| CN102834393B (zh) | 2010-02-03 | 2015-07-22 | 武田药品工业株式会社 | 细胞凋亡信号调节激酶1抑制剂 |
| US8877815B2 (en) | 2010-11-16 | 2014-11-04 | Novartis Ag | Substituted carbamoylcycloalkyl acetic acid derivatives as NEP |
| US8673974B2 (en) | 2010-11-16 | 2014-03-18 | Novartis Ag | Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors |
| WO2012095548A2 (es) | 2011-01-13 | 2012-07-19 | Centro De Investigación Biomédica En Red De Enfermedades Neurodegenerativas (Ciberned) | Compuestos para el tratamiento de enfermedades neurodegenerativas |
| UY35144A (es) | 2012-11-20 | 2014-06-30 | Novartis Ag | Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca |
| JP6295277B2 (ja) | 2013-02-14 | 2018-03-14 | ノバルティス アーゲー | Ｎｅｐ（中性エンドペプチダーゼ）阻害剤としての置換ビスフェニルブタン酸ホスホン酸誘導体 |
| JP2016527249A (ja) | 2013-07-25 | 2016-09-08 | ノバルティス アーゲー | 合成アペリンポリペプチドのバイオコンジュゲート |
| AU2014293386B2 (en) | 2013-07-25 | 2016-11-17 | Novartis Ag | Cyclic polypeptides for the treatment of heart failure |
| BR112017014194A2 (pt) | 2015-01-23 | 2018-01-09 | Novartis Ag | conjugados de ácido graxo de apelina sintéticos com meia-vida melhorada |
| UY38072A (es) | 2018-02-07 | 2019-10-01 | Novartis Ag | Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3100575A1 (de) * | 1981-01-10 | 1982-09-02 | Dr. Karl Thomae Gmbh, 7950 Biberach | "neue benzoesaeuren, ihre herstellung und ihre verwendung als arzneimittel" |
| DE3100535A1 (de) * | 1981-01-10 | 1982-08-12 | Dr. Karl Thomae Gmbh, 7950 Biberach | "neue carbonsaeure-derivate, ihre herstellung und ihre verwendung als arzneimittel" |
| DE3375783D1 (en) * | 1982-07-06 | 1988-04-07 | Thomae Gmbh Dr K | Phenyl-acetic-acid derivatives, their preparation and pharmaceutical compostions containing them |
| FR2554875B1 (fr) * | 1983-11-10 | 1986-02-28 | Dba | Amplificateur hydraulique de freinage |
| DE3347565A1 (de) * | 1983-12-30 | 1985-07-11 | Thomae Gmbh Dr K | Neue phenylessigsaeurederivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE3523466A1 (de) * | 1985-07-01 | 1987-01-08 | Thomae Gmbh Dr K | Neue phenylessigsaeurederivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
-
1983
- 1983-12-30 DE DE19833347565 patent/DE3347565A1/de not_active Withdrawn
-
1984
- 1984-12-20 DK DK613184A patent/DK167439B1/da active Protection Beyond IP Right Term
- 1984-12-20 NZ NZ210657A patent/NZ210657A/xx unknown
- 1984-12-24 JP JP59272685A patent/JPH0623200B2/ja not_active Expired - Lifetime
- 1984-12-27 EP EP84116359A patent/EP0147850B1/de not_active Expired
- 1984-12-27 DE DE1998175044 patent/DE19875044I2/de active Active
- 1984-12-27 AT AT84116359T patent/ATE44027T1/de active
- 1984-12-27 ES ES539078A patent/ES8605500A1/es not_active Expired
- 1984-12-27 DE DE8484116359T patent/DE3478682D1/de not_active Expired
- 1984-12-28 IL IL73963A patent/IL73963A/xx not_active IP Right Cessation
- 1984-12-28 KR KR1019840008504A patent/KR900005320B1/ko not_active Expired
- 1984-12-28 FI FI845145A patent/FI80447C/fi active IP Right Grant
- 1984-12-28 DD DD84272061A patent/DD231348A5/de not_active IP Right Cessation
- 1984-12-28 GR GR82614A patent/GR82614B/el unknown
- 1984-12-28 AU AU37210/84A patent/AU577815B2/en not_active Expired
- 1984-12-28 PT PT79772A patent/PT79772B/pt unknown
- 1984-12-28 CA CA000471120A patent/CA1225398A/en not_active Expired
- 1984-12-28 NO NO845282A patent/NO162819C/no not_active IP Right Cessation
- 1984-12-28 IE IE3349/84A patent/IE57700B1/en not_active IP Right Cessation
- 1984-12-28 HU HU844870A patent/HU194548B/hu unknown
- 1984-12-28 ZA ZA8410103A patent/ZA8410103B/xx unknown
-
1985
- 1985-06-25 DE DE19853522604 patent/DE3522604A1/de not_active Withdrawn
- 1985-08-05 ES ES545881A patent/ES8604546A1/es not_active Expired
- 1985-08-05 ES ES545879A patent/ES8604544A1/es not_active Expired
- 1985-08-05 ES ES545883A patent/ES8604548A1/es not_active Expired
- 1985-08-05 ES ES545882A patent/ES8604547A1/es not_active Expired
- 1985-08-05 ES ES545880A patent/ES8604545A1/es not_active Expired
-
1986
- 1986-06-10 EP EP86107890A patent/EP0207331B1/de not_active Expired - Lifetime
- 1986-06-16 GR GR861558A patent/GR861558B/el unknown
- 1986-06-23 FI FI862650A patent/FI82689C/fi not_active IP Right Cessation
- 1986-06-24 NO NO862532A patent/NO168302C/no not_active IP Right Cessation
- 1986-06-24 AU AU59139/86A patent/AU583631B2/en not_active Expired
- 1986-06-24 DK DK296686A patent/DK167573B1/da not_active IP Right Cessation
- 1986-06-24 ES ES556495A patent/ES8802145A1/es not_active Expired
- 1986-06-24 JP JP61148027A patent/JPH0739405B2/ja not_active Expired - Lifetime
- 1986-06-24 NZ NZ216640A patent/NZ216640A/xx unknown
- 1986-06-24 PT PT82832A patent/PT82832B/pt unknown
- 1986-06-24 CA CA000512269A patent/CA1292000C/en not_active Expired - Lifetime
- 1986-06-24 ZA ZA864695A patent/ZA864695B/xx unknown
- 1986-06-24 IL IL79217A patent/IL79217A/xx not_active IP Right Cessation
-
1991
- 1991-12-27 CS CS914097A patent/CS409791A3/cs unknown
-
1992
- 1992-05-25 SG SG554/92A patent/SG55492G/en unknown
- 1992-06-10 MX MX9202772A patent/MX9202772A/es unknown
- 1992-11-05 HK HK874/92A patent/HK87492A/xx not_active IP Right Cessation
-
1994
- 1994-01-24 BG BG098407A patent/BG61519B2/bg unknown
-
1998
- 1998-10-21 LU LU90301C patent/LU90301I2/fr unknown
- 1998-11-18 NL NL980034C patent/NL980034I1/nl unknown
-
1999
- 1999-07-20 NO NO1999016C patent/NO1999016I1/no unknown
Also Published As
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