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ES8604179A1 - Procedimiento para la preparacion de nuevos derivados tiazo-lidinicos - Google Patents

Procedimiento para la preparacion de nuevos derivados tiazo-lidinicos

Info

Publication number
ES8604179A1
ES8604179A1 ES544286A ES544286A ES8604179A1 ES 8604179 A1 ES8604179 A1 ES 8604179A1 ES 544286 A ES544286 A ES 544286A ES 544286 A ES544286 A ES 544286A ES 8604179 A1 ES8604179 A1 ES 8604179A1
Authority
ES
Spain
Prior art keywords
derivatives
procedure
preparation
new
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES544286A
Other languages
English (en)
Other versions
ES544286A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES8604179A1 publication Critical patent/ES8604179A1/es
Publication of ES544286A0 publication Critical patent/ES544286A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/18—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS DERIVADOS TIZAOLIDINICOS. CONSISTE EN N-ALQUILAR A UN DERIVADO TIZAOLIDINICO 2-SUSTITUIDO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN METANOL, ETANOL, ETER, EN PRESENCIA DE UN AGLUTINANTE DE ACIDOS COMO HIDROXIDOS METALICOS ALCALINOS, CARBONATOS, ALCOHOLATOS Y A LA TEMPERATURA DE EBULLICION DEL DISOLVENTE, PARA OBTENER DERIVADOS TIAZOLIDINICOS DE FORMULA (I). SIENDO: AR UN GRUPO 2-FURILO O UN GRUPO NAFTILO O PIRIDILO SUSTITUIDO POR UNO MAS ATOMOS DE HAL, Y OTROS; X, HAL O UN GRUPO ESTER REACTIVO; Y, N O CH Y Z CIANO O CARBAMOILO. SE UTILIZAN COMO AGENTES ANTI-ULCEROSOS.
ES544286A 1983-03-16 1985-06-17 Procedimiento para la preparacion de nuevos derivados tiazo-lidinicos Expired ES8604179A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU83888A HU188852B (en) 1983-03-16 1983-03-16 Process for producing thiazolidine derivatives active against gastric ulcer and intestinal ulcer

Publications (2)

Publication Number Publication Date
ES8604179A1 true ES8604179A1 (es) 1986-01-16
ES544286A0 ES544286A0 (es) 1986-01-16

Family

ID=10951891

Family Applications (2)

Application Number Title Priority Date Filing Date
ES530738A Granted ES530738A0 (es) 1983-03-16 1984-03-16 Procedimiento para la preparacion de nuevos derivados tiazolidinicos
ES544286A Expired ES8604179A1 (es) 1983-03-16 1985-06-17 Procedimiento para la preparacion de nuevos derivados tiazo-lidinicos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES530738A Granted ES530738A0 (es) 1983-03-16 1984-03-16 Procedimiento para la preparacion de nuevos derivados tiazolidinicos

Country Status (32)

Country Link
US (1) US4616025A (es)
JP (1) JPS59196877A (es)
KR (1) KR840008001A (es)
AT (1) AT383596B (es)
AU (1) AU559753B2 (es)
BE (1) BE899132A (es)
CA (1) CA1273933A (es)
CH (1) CH660592A5 (es)
CS (1) CS241074B2 (es)
DD (1) DD216929A5 (es)
DE (1) DE3409801A1 (es)
DK (1) DK143284A (es)
ES (2) ES530738A0 (es)
FI (1) FI79843C (es)
FR (1) FR2542740B1 (es)
GB (1) GB2140412B (es)
GR (1) GR81883B (es)
HU (1) HU188852B (es)
IE (1) IE57101B1 (es)
IL (1) IL71249A (es)
IN (1) IN157738B (es)
IT (1) IT1196048B (es)
LU (1) LU85248A1 (es)
NL (1) NL8400817A (es)
NO (1) NO162858C (es)
NZ (1) NZ207516A (es)
PL (2) PL142909B1 (es)
PT (1) PT78260B (es)
SE (1) SE455945B (es)
SU (2) SU1240355A3 (es)
YU (1) YU47384A (es)
ZA (1) ZA841938B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6051184A (ja) * 1983-08-30 1985-03-22 Fujimoto Seiyaku Kk Ν−シアノイミノチアゾリジン誘導体およびその製造法
US5204360A (en) * 1985-02-04 1993-04-20 Nihon Bayer Agrochem K.K. Heterocyclic compounds
JPH0730070B2 (ja) * 1985-10-03 1995-04-05 日本バイエルアグロケム株式会社 新規複素環式化合物
JPH0649699B2 (ja) * 1985-02-04 1994-06-29 日本バイエルアグロケム株式会社 ニトロメチレン誘導体、その製法及び殺虫剤
JPH066585B2 (ja) * 1985-02-04 1994-01-26 日本バイエルアグロケム株式会社 ニトロメチレン誘導体、その製法及び殺虫剤
US5001138B1 (en) * 1985-02-04 1998-01-20 Bayer Agrochem Kk Heterocyclic compounds
DE3681465D1 (es) * 1985-02-04 1991-10-24 Nihon Bayer Agrochem K.K., Tokio/Tokyo, Jp
USRE39130E1 (en) 1986-03-07 2006-06-13 Bayer Cropscience K.K. Heterocyclic compounds
JPH0717621B2 (ja) * 1986-03-07 1995-03-01 日本バイエルアグロケム株式会社 新規ヘテロ環式化合物
JP2607369B2 (ja) * 1987-02-20 1997-05-07 興和株式会社 新規な複素環化合物
US5122522A (en) * 1989-06-21 1992-06-16 The Trustees Of The University Of Pennsylvania Treatment and control of ocular development
ES2159661T3 (es) * 1989-06-21 2001-10-16 Univ Pennsylvania Utilizacion de un antagonista muscarinico para la preparacion de un medicamento para el tratamiento y control del desarrollo ocular.
HU207047B (en) * 1989-11-07 1993-03-01 Richter Gedeon Vegyeszet Process for producing new pyridine derivatives and pharmaceutical copositions comprising same
US5240918A (en) * 1992-03-24 1993-08-31 Egis Gyogyszergyar 2-(substituted imino)-thiazolidines and process for the preparation thereof
JP2721805B2 (ja) * 1994-07-22 1998-03-04 日本バイエルアグロケム株式会社 新規ヘテロ環式化合物
DE4427539A1 (de) * 1994-08-04 1996-02-08 Sueddeutsche Kalkstickstoff Verfahren zur Herstellung von 2-Cyaniminothiazolidin
DE4427569A1 (de) * 1994-08-04 1996-02-08 Bayer Ag Verfahren zur Herstellung von Cyanimino-1,3-thiazolidin
DE19904310A1 (de) * 1999-01-28 2000-08-03 Bayer Ag Verfahren zur Herstellung heterocyclischer Verbindungen
KR20020009570A (ko) * 1999-03-05 2002-02-01 도리이 신이찌로 니코틴성 아세틸콜린 α4β2 수용체의 활성화 작용을 가진헤테로시클릭 화합물
US6667401B2 (en) * 2000-01-19 2003-12-23 Bayer Aktiengesellschaft Method for producing heterocyclic compounds
IL158904A0 (en) * 2001-05-25 2004-05-12 Valley Forge Pharmaceuticals Pirenzepine ophthalmic gel
NZ539873A (en) * 2002-11-22 2008-09-26 Smithkline Beecham Corp Novel chemical compounds, thiazolidin-4-one, thiazol-4-one
JP4847314B2 (ja) * 2003-04-07 2011-12-28 コーティカル・ピーティーワイ・リミテッド 炎症性疾患を治療するための新規な方法
NZ590757A (en) * 2008-07-01 2014-05-30 Univ Gifu Novel imino derivative, process for production of the same, and pesticide comprising the same
ES2556470T3 (es) * 2011-09-02 2016-01-18 Bayer Intellectual Property Gmbh Procedimiento para preparar [3-[(6-cloro-3-piridinil)metil]-2-tiazolidiniliden]cianamida

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3264316A (en) * 1963-09-18 1966-08-02 Res Lab Dr C Janssen N V Certain 2-acylimino-3-substitutedthiazoline-4 compounds
DE2205745A1 (de) * 1972-02-08 1973-08-23 Thomae Gmbh Dr K Neue durch den n-cyaniminorest substituierten heterocyclen und verfahren zu ihrer herstellung
US4006156A (en) * 1975-06-27 1977-02-01 Shell Oil Company 3-Alkyl-2-(nitromethylene) thiazolidine
NL7704322A (nl) * 1976-05-03 1977-11-07 Merck & Co Inc Werkwijze voor het bereiden van 2-iminothiazo- lidinen en -thiazolinen.
JPS57171986A (en) * 1981-04-14 1982-10-22 Taiho Yakuhin Kogyo Kk Heterocylic ring compound containing sulfur
JPS5823682A (ja) * 1981-08-03 1983-02-12 Santen Pharmaceut Co Ltd 複素五員環化合物
DE3133918A1 (de) * 1981-08-27 1983-03-17 Bayer Ag, 5090 Leverkusen 2-arylhydrazino-2-thiazoline, acylderivate derselben, 2-arylazo-2-thiazoline, herstellungsverfahren und ihre verwendung zur bekaempfung von ekto- und endoparasiten
JPS58222886A (ja) * 1982-06-19 1983-12-24 Ricoh Co Ltd 感熱記録シ−ト
JPS5933267A (ja) * 1982-08-19 1984-02-23 Fujimoto Seiyaku Kk グアニジン誘導体およびその製造法

Also Published As

Publication number Publication date
IL71249A0 (en) 1984-06-29
IE840655L (en) 1984-09-16
GB8406790D0 (en) 1984-04-18
HU188852B (en) 1986-05-28
FR2542740B1 (fr) 1987-02-20
AT383596B (de) 1987-07-27
PL142749B1 (en) 1987-11-30
FI79843B (fi) 1989-11-30
IL71249A (en) 1987-02-27
SE455945B (sv) 1988-08-22
GB2140412A (en) 1984-11-28
FI841066A0 (fi) 1984-03-16
DE3409801A1 (de) 1984-09-20
AU559753B2 (en) 1987-03-19
CS188584A2 (en) 1985-06-13
BE899132A (fr) 1984-09-12
IN157738B (es) 1986-05-31
PT78260B (en) 1986-04-30
YU47384A (es) 1986-10-31
FI841066L (fi) 1984-09-17
NL8400817A (nl) 1984-10-16
JPS59196877A (ja) 1984-11-08
AU2583384A (en) 1984-09-20
LU85248A1 (fr) 1985-10-14
CH660592A5 (de) 1987-05-15
ES8601170A1 (es) 1985-11-01
IT1196048B (it) 1988-11-10
NO841002L (no) 1984-09-17
SU1240355A3 (ru) 1986-06-23
ES530738A0 (es) 1985-11-01
DD216929A5 (de) 1985-01-02
PL142909B1 (en) 1987-12-31
PL252129A1 (en) 1985-11-19
PT78260A (en) 1984-04-01
CA1273933A (en) 1990-09-11
US4616025A (en) 1986-10-07
FI79843C (fi) 1990-03-12
FR2542740A1 (fr) 1984-09-21
SE8401463L (sv) 1984-09-17
ZA841938B (en) 1985-05-29
PL246683A1 (en) 1985-07-16
CS241074B2 (en) 1986-03-13
DK143284A (da) 1984-09-17
GR81883B (es) 1984-12-12
SU1240356A3 (ru) 1986-06-23
IT8420057A0 (it) 1984-03-15
DK143284D0 (da) 1984-02-29
NZ207516A (en) 1986-06-11
NO162858B (no) 1989-11-20
ATA88284A (de) 1986-12-15
KR840008001A (ko) 1984-12-12
SE8401463D0 (sv) 1984-03-15
IE57101B1 (en) 1992-04-22
NO162858C (no) 1990-02-28
GB2140412B (en) 1987-02-11
ES544286A0 (es) 1986-01-16

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960401