ES8401930A1 - Un procedimiento para preparar derivados de amida del acido nitrobenzoico. - Google Patents
Un procedimiento para preparar derivados de amida del acido nitrobenzoico.Info
- Publication number
- ES8401930A1 ES8401930A1 ES517866A ES517866A ES8401930A1 ES 8401930 A1 ES8401930 A1 ES 8401930A1 ES 517866 A ES517866 A ES 517866A ES 517866 A ES517866 A ES 517866A ES 8401930 A1 ES8401930 A1 ES 8401930A1
- Authority
- ES
- Spain
- Prior art keywords
- acid amide
- nitrobenzoic acid
- amide derivatives
- nitrobenzoic
- sensitizer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/40—2,5-Pyrrolidine-diones
- C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/16—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE AMIDA DEL ACIDO NITROBENZOICO Y DE SUS SALES DE ADICION DE ACIDO FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE N VALE 1 O 2 Y A PUEDE SER VARIOS TIPOS DE RADICALES.CONSISTE EN LA REACCION DE UN ACIDO NITROBENZOICO DE FORMULA (II), O UN DERIVADO REACTIVO DEL MISMO, CON POLIAMIDA DE FORMULA H2N-A-NH2, EN LAS QUE A Y N TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE APROTICO INERTE, EN PRESENCIA DE UN AGENTE CONDENSANTE, A UNA TEMPERATURA ENTRE LA AMBIENTE Y50JC.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO RADIOSENSIBILIZADORES, PARA EL TRATAMIENTO DEL CANCER.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56191228A JPS5892644A (ja) | 1981-11-26 | 1981-11-26 | 新規なニトロ安息香酸アミド誘導体およびそれを含有する放射線増感剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES517866A0 ES517866A0 (es) | 1984-01-01 |
| ES8401930A1 true ES8401930A1 (es) | 1984-01-01 |
Family
ID=16271022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES517866A Expired ES8401930A1 (es) | 1981-11-26 | 1982-11-26 | Un procedimiento para preparar derivados de amida del acido nitrobenzoico. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4474814A (es) |
| EP (1) | EP0081726B1 (es) |
| JP (1) | JPS5892644A (es) |
| KR (1) | KR860001389B1 (es) |
| AU (1) | AU537424B2 (es) |
| CA (1) | CA1191158A (es) |
| DE (1) | DE3264142D1 (es) |
| ES (1) | ES8401930A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0428849A3 (en) * | 1989-09-28 | 1991-07-31 | Hoechst Aktiengesellschaft | Retroviral protease inhibitors |
| KR100544019B1 (ko) * | 2000-12-14 | 2006-01-20 | 주식회사 효성 | 작업성과 도전성이 우수한 도전사 |
| BRPI0512235A (pt) | 2004-06-18 | 2008-02-19 | Ambrx Inc | polipeptìdeos ligadores de antìgenos e seus usos |
| EP2192922A4 (en) | 2007-09-17 | 2010-09-29 | Univ California | INTERNATIONALIZING HUMAN MONOCLONAL ANTIBODIES TO PROMOTE IN SITU ON PROSTATAZELLES |
| ES2975747T3 (es) | 2015-11-30 | 2024-07-12 | Univ California | Administración de carga útil específica de tumor y activación inmunitaria utilizando un anticuerpo humano que se dirige a un antígeno de superficie celular de tumor altamente específico |
| US12049511B2 (en) | 2016-11-10 | 2024-07-30 | Fortis Therapeutics, Inc. | Engineered CD46-specific effector cells and uses thereof in the treatment of cancer |
| US11434301B2 (en) | 2016-11-11 | 2022-09-06 | The Regents Of The University Of California | Anti-CD46 antibodies and methods of use |
| IL312067B2 (en) | 2018-12-21 | 2025-08-01 | Avidity Biosciences Inc | Anti-transferrin receptor antibodies and uses thereof |
| IL296387B2 (en) | 2020-03-19 | 2024-08-01 | Avidity Biosciences Inc | Preparations and methods for the treatment of facial, back and arm muscle atrophy |
| KR20220161378A (ko) | 2020-03-27 | 2022-12-06 | 어비디티 바이오사이언시스 인크. | 근이영양증의 치료용 조성물 및 방법 |
| CN116419747B (zh) | 2020-08-07 | 2025-10-17 | 福蒂斯治疗公司 | 靶向cd46的免疫偶联物及其使用方法 |
| IL311452A (en) | 2021-09-16 | 2024-05-01 | Avidity Biosciences Inc | Compositions and methods of treating facioscapulohumeral muscular dystrophy |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3022268A (en) * | 1958-07-17 | 1962-02-20 | Du Pont | Polyethylene composition |
| BE637259A (es) * | 1962-09-11 | |||
| US3499031A (en) * | 1967-01-03 | 1970-03-03 | Monsanto Co | Diamine process |
| US4009208A (en) * | 1970-08-07 | 1977-02-22 | Sterling Drug Inc. | N,n'-heptamethylenebis(4-methoxybenzamide) |
| US4058523A (en) * | 1974-10-14 | 1977-11-15 | Chugai Seiyaku Kabushiki Kaisha | Bis(benzamido)-benzene derivatives |
-
1981
- 1981-11-26 JP JP56191228A patent/JPS5892644A/ja active Granted
-
1982
- 1982-11-23 US US06/444,339 patent/US4474814A/en not_active Expired - Fee Related
- 1982-11-24 AU AU90848/82A patent/AU537424B2/en not_active Ceased
- 1982-11-25 CA CA000416376A patent/CA1191158A/en not_active Expired
- 1982-11-25 KR KR8205321A patent/KR860001389B1/ko not_active Expired
- 1982-11-26 DE DE8282110963T patent/DE3264142D1/de not_active Expired
- 1982-11-26 ES ES517866A patent/ES8401930A1/es not_active Expired
- 1982-11-26 EP EP82110963A patent/EP0081726B1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| KR840002345A (ko) | 1984-06-25 |
| DE3264142D1 (de) | 1985-07-18 |
| EP0081726B1 (en) | 1985-06-12 |
| JPS6351144B2 (es) | 1988-10-13 |
| KR860001389B1 (ko) | 1986-09-22 |
| US4474814A (en) | 1984-10-02 |
| CA1191158A (en) | 1985-07-30 |
| AU537424B2 (en) | 1984-06-21 |
| ES517866A0 (es) | 1984-01-01 |
| JPS5892644A (ja) | 1983-06-02 |
| AU9084882A (en) | 1983-06-02 |
| EP0081726A1 (en) | 1983-06-22 |
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