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ES8306479A1 - "procedimiento de obtencion de 2-amino-4-hidroxi-5-halogenopirimidinas". - Google Patents

"procedimiento de obtencion de 2-amino-4-hidroxi-5-halogenopirimidinas".

Info

Publication number
ES8306479A1
ES8306479A1 ES82515190A ES515190A ES8306479A1 ES 8306479 A1 ES8306479 A1 ES 8306479A1 ES 82515190 A ES82515190 A ES 82515190A ES 515190 A ES515190 A ES 515190A ES 8306479 A1 ES8306479 A1 ES 8306479A1
Authority
ES
Spain
Prior art keywords
amino
preparation
halo
hydroxy
pyrimidine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES82515190A
Other languages
English (en)
Other versions
ES515190A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ES8306479A1 publication Critical patent/ES8306479A1/es
Publication of ES515190A0 publication Critical patent/ES515190A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE 2-AMINO-4-HIIDROXI-5-HALOGENO-PIRIMIDINAS, DE FORMULA GENERAL (I), EN LA QUE R SIGNIFICA UN GRUPO ALQUILO CON 1 A 4 ATOMOS DE CARBONO O UN GRUPO FENILO; Y X REPRESENTA BROMO O YODO. CONSISTE EN HALOGENAR UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE R TIENE EL SIGNIFICADO YA INDICADO, CON UNA SOLUCION ACIDA DE LOS COMPLEJOS HALOIDEOS DE INTERHALOGENOS. DE APLICACION EN PREPARADOS FARMACEUTICOS PARA COMBATIR LOS VIRUS Y TAMBIEN COMO ESTIMULANTE PARA LA FORMACION DE INTERFERONA.
ES515190A 1981-08-28 1982-08-23 "procedimiento de obtencion de 2-amino-4-hidroxi-5-halogenopirimidinas". Granted ES515190A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU812482A HU187355B (en) 1981-08-28 1981-08-28 Process for preparing 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives

Publications (2)

Publication Number Publication Date
ES8306479A1 true ES8306479A1 (es) 1983-06-01
ES515190A0 ES515190A0 (es) 1983-06-01

Family

ID=10959594

Family Applications (1)

Application Number Title Priority Date Filing Date
ES515190A Granted ES515190A0 (es) 1981-08-28 1982-08-23 "procedimiento de obtencion de 2-amino-4-hidroxi-5-halogenopirimidinas".

Country Status (10)

Country Link
JP (1) JPS5874671A (es)
BE (1) BE894193A (es)
CH (1) CH648833A5 (es)
ES (1) ES515190A0 (es)
FI (1) FI822818A7 (es)
FR (1) FR2512021B1 (es)
GB (1) GB2107309B (es)
HU (1) HU187355B (es)
IT (1) IT1190971B (es)
SU (1) SU1132789A3 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495558B1 (en) 1999-01-22 2002-12-17 Amgen Inc. Kinase inhibitors
EP1144390A2 (en) * 1999-01-22 2001-10-17 Amgen Inc., Kinase inhibitors

Also Published As

Publication number Publication date
HU187355B (en) 1985-12-28
GB2107309B (en) 1985-05-30
FR2512021B1 (fr) 1985-08-09
FI822818A0 (fi) 1982-08-12
SU1132789A3 (ru) 1984-12-30
IT1190971B (it) 1988-02-24
GB2107309A (en) 1983-04-27
ES515190A0 (es) 1983-06-01
JPS5874671A (ja) 1983-05-06
IT8222986A1 (it) 1984-02-26
BE894193A (fr) 1983-02-25
IT8222986A0 (it) 1982-08-26
FR2512021A1 (fr) 1983-03-04
FI822818L (fi) 1983-03-01
FI822818A7 (fi) 1983-03-01
CH648833A5 (de) 1985-04-15

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