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ES8106501A1 - Procedimiento de preparacion de compuestos 1(2h)-isoquinolo-nicos y similares - Google Patents

Procedimiento de preparacion de compuestos 1(2h)-isoquinolo-nicos y similares

Info

Publication number
ES8106501A1
ES8106501A1 ES494891A ES494891A ES8106501A1 ES 8106501 A1 ES8106501 A1 ES 8106501A1 ES 494891 A ES494891 A ES 494891A ES 494891 A ES494891 A ES 494891A ES 8106501 A1 ES8106501 A1 ES 8106501A1
Authority
ES
Spain
Prior art keywords
formula
compounds
procedure
similar
isoquinolo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES494891A
Other languages
English (en)
Other versions
ES494891A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Maruko Pharmaceutical Co Ltd
Taiho Pharmaceutical Co Ltd
Original Assignee
Maruko Pharmaceutical Co Ltd
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maruko Pharmaceutical Co Ltd, Taiho Pharmaceutical Co Ltd filed Critical Maruko Pharmaceutical Co Ltd
Publication of ES494891A0 publication Critical patent/ES494891A0/es
Publication of ES8106501A1 publication Critical patent/ES8106501A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR COMPUESTOS 1(2H)-ISOQUINOLONICOS DE FORMULA (I). CONSISTE EN HACER REACCIONAR UNA (1(2H)-ISOQUINOLONA SUSTITUIDA DE FORMULA (II), EN DONDE Y Y R1 TIENEN LOS SIGNIFICADOS YA DEFINIDOS, DISUELTA EN UN DISOLVENTE ORGANICO EN PRESENCIA DE UN CATALIZADOR BASICO, CON UN HALURO AMINOALQUIL SUSTITUIDO DE FORMULA (III), EN EL CUAL X REPRESENTA UN ATOMO DE HALOGENO TAL COMO CLORO, BROMO O SIMILARES, Y Z R2 Y R3 TIENEN LOS SIGNIFICADOS YA INDICADOS, CALENTANDO LA MEZCLA A UNA TEMPERATURA DE UNOS 80 A 140 GC. DE USO EN PREPARADOS FARMACEUTICOS CON ACTIVIDADES ANALGESICAS, INHIBIDORAS DE LAS SECRECIONES GASTRICAS, ANTIDEPRESORAS, ANTIHISTAMINICAS, ANTICLORINERGICAS Y ANTIULCERA. *FORMULA*
ES494891A 1979-08-21 1980-08-21 Procedimiento de preparacion de compuestos 1(2h)-isoquinolo-nicos y similares Expired ES8106501A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10549779A JPS5677261A (en) 1979-08-21 1979-08-21 1 2h isoquinolone derivative and its acid addition salt

Publications (2)

Publication Number Publication Date
ES494891A0 ES494891A0 (es) 1981-09-01
ES8106501A1 true ES8106501A1 (es) 1981-09-01

Family

ID=14409228

Family Applications (1)

Application Number Title Priority Date Filing Date
ES494891A Expired ES8106501A1 (es) 1979-08-21 1980-08-21 Procedimiento de preparacion de compuestos 1(2h)-isoquinolo-nicos y similares

Country Status (10)

Country Link
JP (1) JPS5677261A (es)
AU (1) AU532023B2 (es)
CA (1) CA1153763A (es)
CH (1) CH646953A5 (es)
DE (1) DE3031574A1 (es)
ES (1) ES8106501A1 (es)
FR (1) FR2463766A1 (es)
GB (1) GB2058783B (es)
IT (1) IT1188988B (es)
NL (1) NL8004736A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2098980B (en) * 1981-03-28 1985-05-15 Taiho Pharmaceutical Co Ltd 1(2h)-isoquinolone compounds and acid addition salts thereof
JPS58164577A (ja) * 1982-03-24 1983-09-29 Taiho Yakuhin Kogyo Kk ４―ベンジル―１―（２ｈ）イソキノロン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3600394A (en) * 1968-05-17 1971-08-17 Searle & Co 2-aminoalkyl-3-arylisocarbostyrils
SE368009B (es) * 1971-09-16 1974-06-17 Kabi Ab
US3928612A (en) * 1974-10-02 1975-12-23 American Home Prod 1,2-Dihydro- and 1,2,3,4-tetrahydro-1-oxo-3-isoquinolinecarboxylic acid derivatives as anti-allergic agents

Also Published As

Publication number Publication date
ES494891A0 (es) 1981-09-01
IT8049519A0 (it) 1980-08-19
GB2058783B (en) 1983-04-07
DE3031574A1 (de) 1981-03-12
JPS5677261A (en) 1981-06-25
IT8049519A1 (it) 1982-02-19
IT1188988B (it) 1988-01-28
GB2058783A (en) 1981-04-15
AU6160980A (en) 1981-04-09
FR2463766A1 (fr) 1981-02-27
FR2463766B1 (es) 1983-09-02
AU532023B2 (en) 1983-09-15
CA1153763A (en) 1983-09-13
NL8004736A (nl) 1981-02-24
CH646953A5 (de) 1984-12-28

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