ES8201138A1 - Improved procedure for the preparation of carbostiril derivatives (Machine-translation by Google Translate, not legally binding) - Google Patents
Improved procedure for the preparation of carbostiril derivatives (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES8201138A1 ES8201138A1 ES498465A ES498465A ES8201138A1 ES 8201138 A1 ES8201138 A1 ES 8201138A1 ES 498465 A ES498465 A ES 498465A ES 498465 A ES498465 A ES 498465A ES 8201138 A1 ES8201138 A1 ES 8201138A1
- Authority
- ES
- Spain
- Prior art keywords
- translation
- derivatives
- machine
- legally binding
- google translate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- -1 ALCOHYL Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 1
- HSFWRNGVRCDJHI-UHFFFAOYSA-N Acetylene Chemical group C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical class O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical class O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDURE FOR THE OBTAINING OF CARBOSTIRILE DERIVATIVES FROM FORMULA (I), WHERE W IS A VINYLENE GROUP; D IS ALCOHYLENE, HYDROXIALCOHYLENE OR XYLYLENE; R1 IS HYDROGEN OR ALCOHYL; R2 IS CYCLOALCOHYL, ARYL, ARALCOHYL, HETEROARYL OR HETEROARALCOHYL, AND R3 AND R4 MAY BE HYDROGEN, HALOGEN, ALCOHYL, AMINO, NITRO OR ACETYLAMINE. IT CONSISTS IN REACTION A CARBOSTYRILE OF FORMULA (II), WHERE AND IS A HALOGEN OR A RADICAR ESTER OF SULPHONYL ACID, WITH A METALLIC SALT OF FORMULA (III), WHETHER IT IS A METAL TO CALINO OR ALKALINE TERRAIN. THE REACTION IS CARRIED OUT IN A SUITABLE ANHYDROUS SOLVENT, IN THE PRESENCE OF AN ALKALINE BASE AND AT A TEMPERATURE BETWEEN 0 C AND THE BOILING TEMPERATURE OF THE SOLVENT. OF APPLICATION FOR ITS POSITIVE INOTHROP EFFECT AND FOR ITS ANTITHROMBOTIC PROPERTIES. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792928583 DE2928583A1 (en) | 1979-07-14 | 1979-07-14 | Substd. alkoxy-carbostyril derivs prodn. - e.g. by cyclising 2-carboxyethyl-1-aminobenzene derivs., useful as antithrombotic and positive inotropic agents |
| FI792426A FI70408C (en) | 1979-07-14 | 1979-08-03 | FRAMEWORK FOR THERAPEUTIC ACTIVATION OF ACTIVE THERAPEUTIC CARBOSTYRILDERIVAT |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES498465A0 ES498465A0 (en) | 1981-12-01 |
| ES8201138A1 true ES8201138A1 (en) | 1981-12-01 |
Family
ID=25779992
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES491859A Granted ES491859A0 (en) | 1979-07-14 | 1980-05-27 | IMPROVED PROCEDURE FOR THE PREPARATION OF CARBOSTIRILE DERIVATIVES |
| ES498466A Expired ES8201139A1 (en) | 1979-07-14 | 1981-01-13 | Improved procedure for the preparation of carbostiril derivatives (Machine-translation by Google Translate, not legally binding) |
| ES498465A Expired ES8201138A1 (en) | 1979-07-14 | 1981-01-13 | Improved procedure for the preparation of carbostiril derivatives (Machine-translation by Google Translate, not legally binding) |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES491859A Granted ES491859A0 (en) | 1979-07-14 | 1980-05-27 | IMPROVED PROCEDURE FOR THE PREPARATION OF CARBOSTIRILE DERIVATIVES |
| ES498466A Expired ES8201139A1 (en) | 1979-07-14 | 1981-01-13 | Improved procedure for the preparation of carbostiril derivatives (Machine-translation by Google Translate, not legally binding) |
Country Status (5)
| Country | Link |
|---|---|
| AT (1) | AT375648B (en) |
| CA (1) | CA1156657A (en) |
| ES (3) | ES491859A0 (en) |
| GR (1) | GR67622B (en) |
| PT (1) | PT71530B (en) |
-
1980
- 1980-04-21 GR GR61730A patent/GR67622B/el unknown
- 1980-05-27 ES ES491859A patent/ES491859A0/en active Granted
- 1980-06-11 AT AT306480A patent/AT375648B/en not_active IP Right Cessation
- 1980-07-10 PT PT7153080A patent/PT71530B/en unknown
- 1980-07-11 CA CA000355992A patent/CA1156657A/en not_active Expired
-
1981
- 1981-01-13 ES ES498466A patent/ES8201139A1/en not_active Expired
- 1981-01-13 ES ES498465A patent/ES8201138A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES498466A0 (en) | 1981-12-01 |
| AT375648B (en) | 1984-08-27 |
| ATA306480A (en) | 1984-01-15 |
| ES8200660A1 (en) | 1981-11-01 |
| ES8201139A1 (en) | 1981-12-01 |
| GR67622B (en) | 1981-08-31 |
| ES498465A0 (en) | 1981-12-01 |
| CA1156657A (en) | 1983-11-08 |
| PT71530A (en) | 1980-08-01 |
| PT71530B (en) | 1981-12-11 |
| ES491859A0 (en) | 1981-11-01 |
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