ES434842A1 - Procedure for the preparation of esters of the oxima of erythromycin. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of esters of the oxima of erythromycin. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES434842A1 ES434842A1 ES434842A ES434842A ES434842A1 ES 434842 A1 ES434842 A1 ES 434842A1 ES 434842 A ES434842 A ES 434842A ES 434842 A ES434842 A ES 434842A ES 434842 A1 ES434842 A1 ES 434842A1
- Authority
- ES
- Spain
- Prior art keywords
- erythromycin
- translation
- esters
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title abstract 6
- 229960003276 erythromycin Drugs 0.000 title abstract 3
- 150000002148 esters Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- MCJGNVYPOGVAJF-UHFFFAOYSA-N quinolin-8-ol Chemical compound C1=CN=C2C(O)=CC=CC2=C1 MCJGNVYPOGVAJF-UHFFFAOYSA-N 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
Landscapes
- Saccharide Compounds (AREA)
Abstract
Procedure for the preparation of esters of erythromycin oxine, characterized in that the erythromycin oxine is reacted with the corresponding acid chloride, aliphatic or aromatic, in a medium consisting of an anhydrous organic solvent inert towards the reaction, in the presence of an alkali metal salt and bringing the reaction to room temperature, to obtain a compound of structural formula (I), defined in the present specification, in which R1 can be an aliphatic or aromatic acyl radical and R2 can be hydrogen or a radical aliphatic or aromatic acyl. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES434842A ES434842A1 (en) | 1975-02-19 | 1975-02-19 | Procedure for the preparation of esters of the oxima of erythromycin. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES434842A ES434842A1 (en) | 1975-02-19 | 1975-02-19 | Procedure for the preparation of esters of the oxima of erythromycin. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES434842A1 true ES434842A1 (en) | 1976-12-01 |
Family
ID=8468656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES434842A Expired ES434842A1 (en) | 1975-02-19 | 1975-02-19 | Procedure for the preparation of esters of the oxima of erythromycin. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES434842A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0033255A1 (en) * | 1980-01-11 | 1981-08-05 | Roussel-Uclaf | Oximes derived from erythromycin A, their preparation, their application in pharmaceuticals and pharmaceutical compositions containing them |
| WO1999025723A1 (en) * | 1997-11-17 | 1999-05-27 | Abbott Laboratories | Chemical synthesis of 6-o-alkyl erythromycin a |
-
1975
- 1975-02-19 ES ES434842A patent/ES434842A1/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0033255A1 (en) * | 1980-01-11 | 1981-08-05 | Roussel-Uclaf | Oximes derived from erythromycin A, their preparation, their application in pharmaceuticals and pharmaceutical compositions containing them |
| WO1999025723A1 (en) * | 1997-11-17 | 1999-05-27 | Abbott Laboratories | Chemical synthesis of 6-o-alkyl erythromycin a |
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