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ES8200370A1 - Procedimiento para la preparacion de nuevas cefalosporinas - Google Patents

Procedimiento para la preparacion de nuevas cefalosporinas

Info

Publication number
ES8200370A1
ES8200370A1 ES491775A ES491775A ES8200370A1 ES 8200370 A1 ES8200370 A1 ES 8200370A1 ES 491775 A ES491775 A ES 491775A ES 491775 A ES491775 A ES 491775A ES 8200370 A1 ES8200370 A1 ES 8200370A1
Authority
ES
Spain
Prior art keywords
formula
preparation
pharmaceutical compositions
compositions containing
cephalosporin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES491775A
Other languages
English (en)
Other versions
ES491775A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES8200370A1 publication Critical patent/ES8200370A1/es
Publication of ES491775A0 publication Critical patent/ES491775A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

PROCEDIMIENTKO PARA LA OBTENCION DE CEFALOSPORINAS DE FORMULA (I), DONDE A, D, E, Y Y R SON DIRENTES RADICALES. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN DERIVADO DE PIPERIDINA DE FORMULA (III), DONDE B ES EL GRUPO -NCO O UN DERIVADO REACTIVO DEL GRUPO -NHCOOH. LA REACCION SE LLEVA A CABO A UNA TEMPERATURA COMPRENDIDA ENTRE -20 Y 50C. Y EN UN MARGEN DE PH COMPRENDIDO ENTRE 2 Y 9. LOS COMPUESTOS ASI OBTENIDOS PUEDEN TRANSFORMARSE POSTERIORMENTE EN EL ACIDO CARBOXILICO LIBRE, EN SUS ESTERES O EN SUS SALES. DE APLICACION COMO ANTIBIOTICO.
ES491775A 1979-06-21 1980-05-23 Procedimiento para la preparacion de nuevas cefalosporinas Granted ES491775A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792924948 DE2924948A1 (de) 1979-06-21 1979-06-21 Neue cephalosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES8200370A1 true ES8200370A1 (es) 1981-10-16
ES491775A0 ES491775A0 (es) 1981-10-16

Family

ID=6073715

Family Applications (4)

Application Number Title Priority Date Filing Date
ES491775A Granted ES491775A0 (es) 1979-06-21 1980-05-23 Procedimiento para la preparacion de nuevas cefalosporinas
ES498522A Granted ES498522A0 (es) 1979-06-21 1981-01-15 Procedimiento para la preparacion de nuevas cefalosporinas
ES498521A Expired ES8200691A1 (es) 1979-06-21 1981-01-15 Procedimiento para la preparacion de nuevas cefalosporinas
ES498520A Granted ES498520A0 (es) 1979-06-21 1981-01-15 Procedimiento para la preparacion de nuevas cefalosporinas

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES498522A Granted ES498522A0 (es) 1979-06-21 1981-01-15 Procedimiento para la preparacion de nuevas cefalosporinas
ES498521A Expired ES8200691A1 (es) 1979-06-21 1981-01-15 Procedimiento para la preparacion de nuevas cefalosporinas
ES498520A Granted ES498520A0 (es) 1979-06-21 1981-01-15 Procedimiento para la preparacion de nuevas cefalosporinas

Country Status (19)

Country Link
US (2) US4316898A (es)
EP (1) EP0021176B1 (es)
JP (1) JPS567791A (es)
AT (1) ATE5886T1 (es)
AU (1) AU536982B2 (es)
CA (1) CA1146537A (es)
DE (2) DE2924948A1 (es)
DK (1) DK261780A (es)
ES (4) ES491775A0 (es)
FI (1) FI68840C (es)
GR (1) GR68107B (es)
HU (1) HU184793B (es)
IE (1) IE49922B1 (es)
IL (1) IL60366A (es)
NO (1) NO801848L (es)
NZ (1) NZ194103A (es)
PH (1) PH17717A (es)
PT (1) PT71440B (es)
ZA (1) ZA803710B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5643288A (en) * 1979-09-18 1981-04-21 Meiji Seika Kaisha Ltd Cephalosporin derivative and its preparation
DE3007685A1 (de) * 1980-02-29 1981-10-01 Dr. Karl Thomae Gmbh, 7950 Biberach Neue cephylosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3038501A1 (de) * 1980-10-11 1982-05-19 Dr. Karl Thomae Gmbh, 7950 Biberach Neue cephalosporine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel
EP0053276A3 (de) * 1980-12-02 1983-08-03 Dr. Karl Thomae GmbH Neue Cephalosporine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3047082A1 (de) * 1980-12-13 1982-07-29 Dr. Karl Thomae Gmbh, 7950 Biberach Neue cephalosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3134776A1 (de) * 1981-09-02 1983-03-10 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 6(alpha)-methoxy-penicilline, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CN102675342A (zh) * 2011-03-15 2012-09-19 四平市精细化学品有限公司 7β-氨基-7α-甲氧基-3-[（1-甲基-1H-四唑-5-基）硫甲基]-3-头孢烯-4-羧酸二苯甲酯的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR208171A1 (es) * 1972-09-29 1976-12-09 Ciba Geigy Ag Procedimiento para la obtencion de nuevos derivados del acido cef-3-em-4-carboxilico
DE2710979A1 (de) * 1977-03-14 1978-09-21 Merck Patent Gmbh Lactame, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
DE2650826A1 (de) * 1976-11-06 1978-05-11 Merck Patent Gmbh Cephemderivate
DE2828261A1 (de) * 1978-06-28 1980-01-10 Thomae Gmbh Dr K Neue penicilline, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
FI801979A7 (fi) 1980-12-22
AU536982B2 (en) 1984-05-31
ES8200690A1 (es) 1981-11-01
CA1146537A (en) 1983-05-17
FI68840C (fi) 1985-11-11
DE2924948A1 (de) 1981-01-22
ES491775A0 (es) 1981-10-16
EP0021176B1 (de) 1984-01-18
IE801289L (en) 1980-12-21
PT71440A (de) 1980-07-01
ATE5886T1 (de) 1984-02-15
IL60366A (en) 1984-02-29
AU5947180A (en) 1981-01-08
PH17717A (en) 1984-11-21
IL60366A0 (en) 1980-09-16
US4388315A (en) 1983-06-14
US4316898A (en) 1982-02-23
ZA803710B (en) 1982-02-24
EP0021176A3 (en) 1981-12-23
GR68107B (es) 1981-10-30
EP0021176A2 (de) 1981-01-07
HU184793B (en) 1984-10-29
ES498521A0 (es) 1981-11-01
DE3066148D1 (en) 1984-02-23
NO801848L (no) 1980-12-22
NZ194103A (en) 1984-07-06
ES498520A0 (es) 1981-11-01
PT71440B (de) 1981-10-23
ES8200691A1 (es) 1981-11-01
DK261780A (da) 1980-12-22
FI68840B (fi) 1985-07-31
JPS567791A (en) 1981-01-27
ES8200692A1 (es) 1981-11-01
IE49922B1 (en) 1986-01-08
ES498522A0 (es) 1981-11-01

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