ES8104323A1 - Un procedimiento para obtener 2,6-diaminonebularinas - Google Patents
Un procedimiento para obtener 2,6-diaminonebularinasInfo
- Publication number
- ES8104323A1 ES8104323A1 ES490101A ES490101A ES8104323A1 ES 8104323 A1 ES8104323 A1 ES 8104323A1 ES 490101 A ES490101 A ES 490101A ES 490101 A ES490101 A ES 490101A ES 8104323 A1 ES8104323 A1 ES 8104323A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- image
- compound
- amino
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- RTRQQBHATOEIAF-UUOKFMHZSA-N acadesine Chemical compound NC1=C(C(=O)N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 RTRQQBHATOEIAF-UUOKFMHZSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
- Luminescent Compositions (AREA)
Abstract
PROCEDIMIENTO PARA OBTENER 2,6-DIAMINONEBULARINAS, DE FORMULA (I), EN DONDE R ES FENILO, QUE PUEDE ESTAR SUSTITUIDO; O SU SAL DE ADICION DE ACIDO. COMPRENDE HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA *FORMULA*; R ELEVADO A 1, R ELEVADO A 2 Y R ELEVADO A 3, INDEPENDIENTEMENTE UNO DE OTRO, SON HIDROXILO; X ES AMINO QUE PUEDE ESTAR SUSTITUIDO, O ALCOHILO INFERIOR. ESTOS COMPUESTOS TIENEN ACCION SOBRE LA CORONARIA COMO VASODILATADORES Y COMO INHIBIDORES DE LA AGRUPACION DE PLAQUETAS. *FORMULA* T
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3956279A JPS55130998A (en) | 1979-04-02 | 1979-04-02 | N2-substituted 2,6-diaminonebularin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES490101A0 ES490101A0 (es) | 1981-04-01 |
| ES8104323A1 true ES8104323A1 (es) | 1981-04-01 |
Family
ID=12556512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES490101A Expired ES8104323A1 (es) | 1979-04-02 | 1980-03-31 | Un procedimiento para obtener 2,6-diaminonebularinas |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4293690A (es) |
| EP (1) | EP0017465A1 (es) |
| JP (1) | JPS55130998A (es) |
| AU (1) | AU5698280A (es) |
| DK (1) | DK134580A (es) |
| ES (1) | ES8104323A1 (es) |
| FI (1) | FI801033A7 (es) |
| GR (1) | GR67615B (es) |
| IL (1) | IL59602A0 (es) |
| NO (1) | NO800868L (es) |
| NZ (1) | NZ193324A (es) |
| PH (1) | PH15849A (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56152437U (es) * | 1980-04-14 | 1981-11-14 | ||
| JPS60193997A (ja) * | 1984-03-14 | 1985-10-02 | Sumitomo Chem Co Ltd | 新規シアノイミダゾ−ルリボヌクレオシド誘導体およびその製造法 |
| US5063233A (en) * | 1986-11-14 | 1991-11-05 | Ciba-Geigy Corporation | N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists |
| US4954504A (en) * | 1986-11-14 | 1990-09-04 | Ciba-Geigy Corporation | N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity |
| US4968697A (en) * | 1987-02-04 | 1990-11-06 | Ciba-Geigy Corporation | 2-substituted adenosine 5'-carboxamides as antihypertensive agents |
| WO1991010671A1 (en) * | 1990-01-11 | 1991-07-25 | Isis Pharmaceuticals, Inc. | Compositions and methods for detecting and modulating rna activity and gene expression |
| US6262241B1 (en) | 1990-08-13 | 2001-07-17 | Isis Pharmaceuticals, Inc. | Compound for detecting and modulating RNA activity and gene expression |
| DE19718065A1 (de) * | 1997-04-29 | 1998-11-05 | Henkel Kgaa | Reinigungsmittel für nachvernetzende Polyurethan-Hotmelts |
| ES2192495B1 (es) * | 2002-03-21 | 2005-02-16 | Universidad De Barcelona | Nuevo uso terapeutico del ribosido de 5-aminoimidazol-4-carboxamida (acadesina). |
| JP2005530772A (ja) * | 2002-05-09 | 2005-10-13 | ミモトープス・プロプライエタリー・リミテッド | アミノ酸類縁体 |
| WO2005097140A2 (en) * | 2004-04-02 | 2005-10-20 | Adenosine Therapeutics, Llc | Selective antagonists of a2a adenosine receptors |
| CN119792485B (zh) * | 2025-03-17 | 2025-06-24 | 温州医科大学附属口腔医院 | 一种抑菌促修复水凝胶敷料及制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3134778A (en) * | 1963-08-20 | 1964-05-26 | Smith Kline French Lab | 2,5,7-triamino-4-phenyl (or thienyl)-pyrimido[4,5-d]pyrimidines |
| FR1535561A (fr) * | 1966-06-18 | 1968-08-09 | Ajinomoto Kk | Méthode de préparation de l'adénine, de ses dérivés et intermédiaires |
| US3857842A (en) * | 1970-05-06 | 1974-12-31 | Sagami Chem Res | Process for preparing purine compounds by reaction of a carbonitrile with formic acid |
| US3826803A (en) * | 1972-02-17 | 1974-07-30 | Icn Pharmaceuticals | Arabinofuranosyl-8-azaadenines |
| DE2359536C2 (de) * | 1972-12-08 | 1984-08-02 | Takeda Chemical Industries, Ltd., Osaka | 2,6-Diaminonebularinderivate |
| US4056674A (en) * | 1973-07-06 | 1977-11-01 | Icn Pharmaceuticals, Inc. | Derivatives of 3-deazaguanine |
| JPS5461194A (en) * | 1977-10-21 | 1979-05-17 | Takeda Chem Ind Ltd | Preparation of n22substituted 2*66diaminonebularin |
-
1979
- 1979-04-02 JP JP3956279A patent/JPS55130998A/ja active Pending
-
1980
- 1980-03-12 IL IL59602A patent/IL59602A0/xx unknown
- 1980-03-25 NO NO800868A patent/NO800868L/no unknown
- 1980-03-28 US US06/136,072 patent/US4293690A/en not_active Expired - Lifetime
- 1980-03-28 DK DK134580A patent/DK134580A/da unknown
- 1980-03-31 AU AU56982/80A patent/AU5698280A/en not_active Abandoned
- 1980-03-31 GR GR61579A patent/GR67615B/el unknown
- 1980-03-31 ES ES490101A patent/ES8104323A1/es not_active Expired
- 1980-04-01 EP EP80301024A patent/EP0017465A1/en not_active Withdrawn
- 1980-04-01 PH PH23848A patent/PH15849A/en unknown
- 1980-04-01 FI FI801033A patent/FI801033A7/fi not_active Application Discontinuation
- 1980-04-01 NZ NZ193324A patent/NZ193324A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU5698280A (en) | 1980-10-09 |
| NO800868L (no) | 1980-10-03 |
| US4293690A (en) | 1981-10-06 |
| NZ193324A (en) | 1982-09-07 |
| IL59602A0 (en) | 1980-06-30 |
| ES490101A0 (es) | 1981-04-01 |
| PH15849A (en) | 1983-04-13 |
| FI801033A7 (fi) | 1981-01-01 |
| EP0017465A1 (en) | 1980-10-15 |
| GR67615B (es) | 1981-08-31 |
| DK134580A (da) | 1980-10-03 |
| JPS55130998A (en) | 1980-10-11 |
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