ES8103054A1 - Procedimiento para la preparacion de nuevas 2-fenilimino- imidazolidinas disustituidas en 3,4 - Google Patents
Procedimiento para la preparacion de nuevas 2-fenilimino- imidazolidinas disustituidas en 3,4Info
- Publication number
- ES8103054A1 ES8103054A1 ES486967A ES486967A ES8103054A1 ES 8103054 A1 ES8103054 A1 ES 8103054A1 ES 486967 A ES486967 A ES 486967A ES 486967 A ES486967 A ES 486967A ES 8103054 A1 ES8103054 A1 ES 8103054A1
- Authority
- ES
- Spain
- Prior art keywords
- fluoro
- acid addition
- group
- imidazolidines
- phenylimino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 3,4-Disubstituted 2-phenylimino-imidazolidines Chemical class 0.000 title abstract 13
- 239000002253 acid Substances 0.000 title abstract 5
- 150000003839 salts Chemical class 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 238000007792 addition Methods 0.000 abstract 4
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- HKWFCVUHNYCCNR-UHFFFAOYSA-N 1-n-(4,5-dihydro-1h-imidazol-2-yl)-4-fluorobenzene-1,3-diamine Chemical compound C1=C(F)C(N)=CC(N=C2NCCN2)=C1 HKWFCVUHNYCCNR-UHFFFAOYSA-N 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O ammonium group Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- NHDLMBUAIWPQQA-UHFFFAOYSA-N n-(4-fluoro-3-nitrophenyl)-4,5-dihydro-1h-imidazol-2-amine Chemical compound C1=C(F)C([N+](=O)[O-])=CC(NC=2NCCN=2)=C1 NHDLMBUAIWPQQA-UHFFFAOYSA-N 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Luminescent Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Photoreceptors In Electrophotography (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE 2-FENILIMINO-IMIDAZOLIDINAS DISUSTITUIDAS EN 3.4 DE FORMULA GENERAL: *FORMULA*, ASI COMO DE SUS SALES POR ADICCION DE ACIDOS. Z REPRESENTA DISTINTOS TIPOS DE RADICALES. SE OBTIENE HACIENDO REACCIONAR UN COMPUESTO DE FORMULA: *FORMULA* DONDE X E Y PUEDEN SER IGUALES O DIFERENTES Y REPRESENTA ATOMOS O RADICALES DIVERSOS, CON ETILEN DIAMINA TRRANSFORMANDOSE EN EL COMPUESTO DESEADO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS Y TERAPEUTICAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782854659 DE2854659A1 (de) | 1978-12-18 | 1978-12-18 | Neue 3,4-disubstituierte 2-phenylimino-imidazolidine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8103054A1 true ES8103054A1 (es) | 1981-02-16 |
| ES486967A0 ES486967A0 (es) | 1981-02-16 |
Family
ID=6057553
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES486971A Expired ES8100272A1 (es) | 1978-12-18 | 1979-12-17 | Procedimiento para la preparacion de una nueva 2-(4-fluoro-3-amino fenilimino)-imidazolidina |
| ES486970A Granted ES486970A0 (es) | 1978-12-18 | 1979-12-17 | Procedimiento para la preparacion de nuevas 2-fenilimino-i- midazolidinas disustituidas en 3,4 |
| ES486967A Granted ES486967A0 (es) | 1978-12-18 | 1979-12-17 | Procedimiento para la preparacion de nuevas 2-fenilimino- imidazolidinas disustituidas en 3,4 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES486971A Expired ES8100272A1 (es) | 1978-12-18 | 1979-12-17 | Procedimiento para la preparacion de una nueva 2-(4-fluoro-3-amino fenilimino)-imidazolidina |
| ES486970A Granted ES486970A0 (es) | 1978-12-18 | 1979-12-17 | Procedimiento para la preparacion de nuevas 2-fenilimino-i- midazolidinas disustituidas en 3,4 |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0012822B1 (es) |
| JP (1) | JPS5583754A (es) |
| AT (1) | ATE1903T1 (es) |
| AU (1) | AU526539B2 (es) |
| CA (1) | CA1112648A (es) |
| DE (2) | DE2854659A1 (es) |
| DK (1) | DK146821C (es) |
| ES (3) | ES8100272A1 (es) |
| FI (1) | FI68814C (es) |
| GR (1) | GR73913B (es) |
| IE (1) | IE49239B1 (es) |
| IL (1) | IL58971A (es) |
| NO (1) | NO148555C (es) |
| NZ (1) | NZ192426A (es) |
| PH (1) | PH22130A (es) |
| PT (1) | PT70592A (es) |
| YU (1) | YU41901B (es) |
| ZA (1) | ZA796832B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2933930A1 (de) * | 1979-08-22 | 1981-03-12 | C.H. Boehringer Sohn, 6507 Ingelheim | 2-(2-chlor-4-cyclopropyl-phenylimino)-imidazolidin, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben. |
| HU192986B (en) * | 1984-05-23 | 1987-08-28 | Egyt Gyogyszervegyeszeti Gyar | Process for production of imidasodiline derivatives |
| CA2196792A1 (en) | 1994-08-04 | 1996-02-15 | Yoon T. Jeon | Novel benzimidazole derivatives |
| DE19514579A1 (de) | 1995-04-20 | 1996-10-24 | Boehringer Ingelheim Kg | Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz |
| DK0944603T3 (da) * | 1996-11-25 | 2003-06-16 | Procter & Gamble | Fremgangsmåde til fremstilling af 2-amino-2-imidazolin-, guanidin- og 2-amino-3,4,5,6-tetrahydropyrimidin-derivater |
| US6495583B1 (en) | 1997-03-25 | 2002-12-17 | Synaptic Pharmaceutical Corporation | Benzimidazole derivatives |
| US6066740A (en) * | 1997-11-25 | 2000-05-23 | The Procter & Gamble Company | Process for making 2-amino-2-imidazoline, guanidine and 2-amino-3,4,5,6-tetrahydropyrimidine derivatives |
| CN111303038A (zh) * | 2020-03-18 | 2020-06-19 | 滨州德润化工有限责任公司 | 一种油田水处理用缓蚀剂两性咪唑啉制作工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL123037C (es) * | 1963-10-04 | |||
| FR1506407A (fr) * | 1965-10-01 | 1967-12-22 | Boehringer Sohn Ingelheim | Procédé pour fabriquer des dérivés du 2-anilino-1, 3-diazacyclopentène-(2) |
| DE1545628A1 (de) * | 1965-10-01 | 1970-06-25 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von blutdrucksenkend und sedativ wirksamen Derivaten des 2-(2-Halogenanilino)-1,3-diazacyclopentens-(2) |
| AT278775B (de) * | 1967-01-19 | 1970-02-10 | Chinoin Gyogyszer Es Vegyeszet | Verfahren zur Herstellung von Δ<2>-Imidazolinderivaten und ihren Salzen |
| AT330769B (de) * | 1974-04-05 | 1976-07-26 | Chemie Linz Ag | Verfahren zur herstellung von 2-arylamino- 2-imidazolin-derivaten und ihren salzen |
| DE2806775A1 (de) * | 1978-02-17 | 1979-08-30 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
-
1978
- 1978-12-18 DE DE19782854659 patent/DE2854659A1/de not_active Withdrawn
-
1979
- 1979-11-08 AT AT79104381T patent/ATE1903T1/de not_active IP Right Cessation
- 1979-11-08 EP EP79104381A patent/EP0012822B1/de not_active Expired
- 1979-11-08 DE DE7979104381T patent/DE2964166D1/de not_active Expired
- 1979-11-28 GR GR60628A patent/GR73913B/el unknown
- 1979-12-13 PT PT70592A patent/PT70592A/pt unknown
- 1979-12-17 AU AU53893/79A patent/AU526539B2/en not_active Ceased
- 1979-12-17 DK DK537179A patent/DK146821C/da not_active IP Right Cessation
- 1979-12-17 ES ES486971A patent/ES8100272A1/es not_active Expired
- 1979-12-17 NO NO794114A patent/NO148555C/no unknown
- 1979-12-17 YU YU3089/79A patent/YU41901B/xx unknown
- 1979-12-17 IE IE2447/79A patent/IE49239B1/en unknown
- 1979-12-17 FI FI793948A patent/FI68814C/fi not_active IP Right Cessation
- 1979-12-17 ES ES486970A patent/ES486970A0/es active Granted
- 1979-12-17 IL IL58971A patent/IL58971A/xx unknown
- 1979-12-17 CA CA342,041A patent/CA1112648A/en not_active Expired
- 1979-12-17 ES ES486967A patent/ES486967A0/es active Granted
- 1979-12-17 NZ NZ192426A patent/NZ192426A/en unknown
- 1979-12-17 JP JP16289679A patent/JPS5583754A/ja active Granted
- 1979-12-18 ZA ZA00796832A patent/ZA796832B/xx unknown
-
1983
- 1983-03-22 PH PH28680A patent/PH22130A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT70592A (de) | 1980-01-01 |
| ES8102100A1 (es) | 1980-12-16 |
| NO148555C (no) | 1983-11-23 |
| DE2964166D1 (en) | 1983-01-05 |
| IE49239B1 (en) | 1985-09-04 |
| ATE1903T1 (de) | 1982-12-15 |
| IL58971A0 (en) | 1980-03-31 |
| GR73913B (es) | 1984-05-22 |
| AU5389379A (en) | 1980-06-26 |
| CA1112648A (en) | 1981-11-17 |
| EP0012822B1 (de) | 1982-12-01 |
| DK146821C (da) | 1984-06-25 |
| EP0012822A1 (de) | 1980-07-09 |
| DK146821B (da) | 1984-01-16 |
| FI68814B (fi) | 1985-07-31 |
| NO794114L (no) | 1980-06-19 |
| IE792447L (en) | 1980-06-18 |
| NO148555B (no) | 1983-07-25 |
| NZ192426A (en) | 1984-07-06 |
| PH22130A (en) | 1988-06-01 |
| YU308979A (en) | 1983-04-30 |
| ES486970A0 (es) | 1980-12-16 |
| FI68814C (fi) | 1985-11-11 |
| FI793948A7 (fi) | 1980-06-19 |
| JPH0118071B2 (es) | 1989-04-03 |
| YU41901B (en) | 1988-02-29 |
| DK537179A (da) | 1980-06-19 |
| AU526539B2 (en) | 1983-01-20 |
| ES486971A0 (es) | 1980-11-01 |
| ES486967A0 (es) | 1981-02-16 |
| ES8100272A1 (es) | 1980-11-01 |
| ZA796832B (en) | 1981-08-26 |
| IL58971A (en) | 1984-03-30 |
| DE2854659A1 (de) | 1980-07-10 |
| JPS5583754A (en) | 1980-06-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IE791565L (en) | Crop cutting apparatus | |
| ES8102100A1 (es) | Procedimiento para la preparacion de nuevas 2-fenilimino-i- midazolidinas disustituidas en 3,4 | |
| EP0046337A3 (en) | Triazole compounds, a process for preparing them, their use as plant and pharmaceutical fungicides and as plant growth regulators and compositions containing them | |
| ES8707723A1 (es) | Un procedimiento para la preparacion de derivados de 1,5-benzotiazepina | |
| DE3272824D1 (en) | Novel substituted imidazoles and triazoles, fungicidal compositions containing them, the use thereof for combating fungi and processes for the preparation of intermediates for making the imidazoles and triazoles | |
| BR8603787A (pt) | Compostos heterociclicos,e,processo de sua preparacao e aplicacao | |
| ES8102110A1 (es) | Procedimiento para la preparacion de acido 1,2,3-tiadiazol- 5-il-tioglicolico | |
| ES2042514T3 (es) | Procedimiento para preparar acidos alfa-amino-alquil-fosfonicos. | |
| ES481603A1 (es) | Un procedimiento para la preparacion de un derivado de la hidantoina. | |
| GB1428893A (en) | Fungicidal compositions based on organic phosphites | |
| KR870003055A (ko) | 살충성 화합물 | |
| GB2102002B (en) | Herbically active derivatives of n-alkyl-substituted amino methyl phosphonic acid and process for preparing same | |
| ES443472A1 (es) | Un procedimiento para la preparacion de nuevas tidiazolili- midazolinas. | |
| HUT45016A (en) | Herbicides containing as active substance derivatives of piridil-phenil-ether and process for production of these derivatives | |
| ATE25680T1 (de) | Verfahren zur herstellung von 4-amino-5-dialkoxy- methylpyrimidinderivaten. | |
| FR2429789A1 (fr) | Synthese totale de la substance utero-evacuante d,l-zoapatanol, derivee de la plante zoapatle | |
| JPS5545633A (en) | N-substituted alkylene-bisdithiocarbamate | |
| GB1322528A (en) | Insecticidal and fungicidal compositions and methods using the thiophosphate esters | |
| ES8405397A1 (es) | Procedimiento para la preparacion de esteres de acido lisergico. |