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ES557703A0 - Un procedimiento para preparar 5,8,13,14-tetrahido-(9- y 12 -hidroxi)-14-metilben (5,6)-isoindolo (2,1-b)isoquinolin-8,13-diona - Google Patents

Un procedimiento para preparar 5,8,13,14-tetrahido-(9- y 12 -hidroxi)-14-metilben (5,6)-isoindolo (2,1-b)isoquinolin-8,13-diona

Info

Publication number
ES557703A0
ES557703A0 ES557703A ES557703A ES557703A0 ES 557703 A0 ES557703 A0 ES 557703A0 ES 557703 A ES557703 A ES 557703A ES 557703 A ES557703 A ES 557703A ES 557703 A0 ES557703 A0 ES 557703A0
Authority
ES
Spain
Prior art keywords
tetrahido
hidroxi
isoindolo
methylben
diona
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES557703A
Other languages
English (en)
Other versions
ES8801212A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES8801212A1 publication Critical patent/ES8801212A1/es
Publication of ES557703A0 publication Critical patent/ES557703A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES557703A 1985-05-29 1987-08-31 Un procedimiento para preparar 5,8,13,14-tetrahido-(9- y 12 -hidroxi)-14-metilben (5,6)-isoindolo (2,1-b)isoquinolin-8,13-diona Expired ES8801212A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858513460A GB8513460D0 (en) 1985-05-29 1985-05-29 Chemical compounds

Publications (2)

Publication Number Publication Date
ES8801212A1 ES8801212A1 (es) 1988-01-01
ES557703A0 true ES557703A0 (es) 1988-01-01

Family

ID=10579796

Family Applications (2)

Application Number Title Priority Date Filing Date
ES555407A Expired ES8800942A1 (es) 1985-05-29 1986-05-28 Un procedimiento para preparar derivados de isoquinolina
ES557703A Expired ES8801212A1 (es) 1985-05-29 1987-08-31 Un procedimiento para preparar 5,8,13,14-tetrahido-(9- y 12 -hidroxi)-14-metilben (5,6)-isoindolo (2,1-b)isoquinolin-8,13-diona

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES555407A Expired ES8800942A1 (es) 1985-05-29 1986-05-28 Un procedimiento para preparar derivados de isoquinolina

Country Status (18)

Country Link
US (1) US4900737A (es)
JP (1) JPS6212778A (es)
KR (1) KR860009015A (es)
BE (1) BE904835A (es)
CH (2) CH668596A5 (es)
DE (1) DE3617938A1 (es)
DK (1) DK246986A (es)
ES (2) ES8800942A1 (es)
FI (1) FI862277A7 (es)
FR (1) FR2584072B1 (es)
GB (2) GB8513460D0 (es)
IT (1) IT1191931B (es)
NL (1) NL8601381A (es)
NO (1) NO862120L (es)
NZ (1) NZ216338A (es)
PH (2) PH24002A (es)
SE (2) SE8602434L (es)
ZA (1) ZA864015B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK616087A (da) * 1986-11-27 1988-05-28 Glaxo Group Ltd Isoquinolinderivater og farmaceutiske praeparater indeholdende dem
GB8800312D0 (en) * 1988-01-07 1988-02-10 Glaxo Group Ltd Process
FR2801309B1 (fr) * 1999-11-18 2002-01-04 Adir Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN114805204B (zh) * 2022-04-01 2023-09-15 云南师范大学 一种制备4-碘异喹啉-1(2h)-酮类化合物的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029659A (en) * 1971-03-29 1977-06-14 Omnium Chimique Societe Anonyme N-disubstituted aminoethyl esters of 11-methoxy-raubasinic acid
US3894029A (en) * 1971-08-26 1975-07-08 Basf Ag Production of camptothecin and camptothecin-like compounds
US3903276A (en) * 1972-03-20 1975-09-02 American Home Prod N-carboxymethyl-N-substituted glycinate esters of 3-hydroxy-1,4-benzodiazepin-2-ones for inducing a calming effect
US4301285A (en) * 1980-10-02 1981-11-17 American Home Products Corporation Sydnonimine CNS stimulants
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
DK158666C (da) * 1982-11-04 1990-11-19 Glaxo Group Ltd Analogifremgangsmaade til fremstilling af 5,14-dihydrobenz-oe5,6aa-isoindolooe2,1-baa-isoquinolin-8,13-dion
DE3576066D1 (de) * 1984-05-03 1990-03-29 Glaxo Group Ltd Isochinolinderivate.

Also Published As

Publication number Publication date
FR2584072B1 (fr) 1991-04-19
BE904835A (fr) 1986-11-28
CH671959A5 (es) 1989-10-13
ES8801212A1 (es) 1988-01-01
SE8602434D0 (sv) 1986-05-28
IT1191931B (it) 1988-03-31
AU591905B2 (en) 1989-12-21
SE8602434L (sv) 1986-11-30
GB2175587B (en) 1989-10-11
JPS6212778A (ja) 1987-01-21
KR860009015A (ko) 1986-12-19
CH668596A5 (de) 1989-01-13
GB8513460D0 (en) 1985-07-03
DK246986D0 (da) 1986-05-27
NO862120L (no) 1986-12-01
NZ216338A (en) 1989-03-29
IT8648070A0 (it) 1986-05-28
SE8904107D0 (sv) 1989-12-05
DE3617938A1 (de) 1986-12-04
FR2584072A1 (fr) 1987-01-02
DK246986A (da) 1986-11-30
PH24002A (en) 1990-02-09
US4900737A (en) 1990-02-13
SE464523B (sv) 1991-05-06
NL8601381A (nl) 1986-12-16
ZA864015B (en) 1988-01-27
GB2175587A (en) 1986-12-03
ES8800942A1 (es) 1987-12-01
GB8612950D0 (en) 1986-07-02
FI862277A7 (fi) 1986-11-30
FI862277A0 (fi) 1986-05-29
ES555407A0 (es) 1987-12-01
PH24375A (en) 1990-06-13
AU5807386A (en) 1986-12-04

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