ES528122A0 - Procedimiento de preparacion de derivados de yantina como divisional de la solicitud de patente de invencion numero 515.936,solicitada el 24 de septiembre de 1982)(como divisional de la patente numero 515.936) - Google Patents
Procedimiento de preparacion de derivados de yantina como divisional de la solicitud de patente de invencion numero 515.936,solicitada el 24 de septiembre de 1982)(como divisional de la patente numero 515.936)Info
- Publication number
- ES528122A0 ES528122A0 ES528122A ES528122A ES528122A0 ES 528122 A0 ES528122 A0 ES 528122A0 ES 528122 A ES528122 A ES 528122A ES 528122 A ES528122 A ES 528122A ES 528122 A0 ES528122 A0 ES 528122A0
- Authority
- ES
- Spain
- Prior art keywords
- divisional
- omega
- atoms
- yantina
- september
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000018569 Respiratory Tract disease Diseases 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000000414 obstructive effect Effects 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
- C07C29/10—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C31/34—Halogenated alcohols
- C07C31/42—Polyhydroxylic acyclic alcohols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/16—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/20—Free hydroxyl or mercaptan
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Epoxy Compounds (AREA)
- Saccharide Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813138397 DE3138397A1 (de) | 1981-09-26 | 1981-09-26 | "arzneimittel, darin enthaltene vicinale dihydroxyalkylxanthine und herstellungsverfahren fuer diese xanthinverbindungen" |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES528122A0 true ES528122A0 (es) | 1984-08-01 |
| ES8406479A1 ES8406479A1 (es) | 1984-08-01 |
Family
ID=6142714
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES515936A Expired ES8606346A1 (es) | 1981-09-26 | 1982-09-24 | "procedimiento de preparacion de derivados de xantina". |
| ES528122A Expired ES8406479A1 (es) | 1981-09-26 | 1983-12-16 | Procedimiento de preparacion de derivados de yantina como divisional de la solicitud de patente de invencion numero 515.936,solicitada el 24 de septiembre de 1982)(como divisional de la patente numero 515.936) |
| ES528123A Expired ES8407048A1 (es) | 1981-09-26 | 1983-12-16 | Procedimiento de preparacion de derivados de xantina (como divisional de la solicitud de patente de invencion no.515936, solicitada el 24.9.82) |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES515936A Expired ES8606346A1 (es) | 1981-09-26 | 1982-09-24 | "procedimiento de preparacion de derivados de xantina". |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES528123A Expired ES8407048A1 (es) | 1981-09-26 | 1983-12-16 | Procedimiento de preparacion de derivados de xantina (como divisional de la solicitud de patente de invencion no.515936, solicitada el 24.9.82) |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US4616020A (es) |
| EP (1) | EP0075850B1 (es) |
| JP (1) | JP2550301B2 (es) |
| KR (1) | KR880002300B1 (es) |
| AT (1) | ATE17005T1 (es) |
| AU (1) | AU554227B2 (es) |
| CA (1) | CA1286292C (es) |
| DE (2) | DE3138397A1 (es) |
| DK (1) | DK148844C (es) |
| ES (3) | ES8606346A1 (es) |
| FI (1) | FI73681C (es) |
| GR (1) | GR76734B (es) |
| HU (1) | HU186125B (es) |
| IE (1) | IE53911B1 (es) |
| IL (1) | IL66864A0 (es) |
| NO (1) | NO158678C (es) |
| PT (1) | PT75604B (es) |
| ZA (1) | ZA827012B (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4636507A (en) * | 1984-04-30 | 1987-01-13 | Hoechst-Roussel Pharmaceuticals Inc. | Host defense mechanism enhancement |
| DE3525801A1 (de) * | 1985-07-19 | 1987-01-22 | Hoechst Ag | Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung |
| CA1332939C (en) * | 1986-08-07 | 1994-11-08 | Henrich Hasko Paradies | 2,5,6-substituted-n -alkylpyrimidines |
| FR2611716A1 (fr) * | 1987-03-06 | 1988-09-09 | Uriach Cia Sa J | Derives de diisobutylxanthine substituee en position 7 utiles comme bronchodilatateurs, procede pour leur preparation et composition pharmaceutique les contenant |
| JP2661666B2 (ja) * | 1988-02-19 | 1997-10-08 | ヘキスト薬品工業株式会社 | 抗消化性潰瘍剤 |
| DE4109169A1 (de) * | 1991-03-20 | 1992-09-24 | Koehler Chemie Dr Franz | Wasserloesliche nicht ionische roentgenkontrastmittel sowie mittel und verfahren zu ihrer herstellung |
| US5342841A (en) * | 1992-03-12 | 1994-08-30 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivatives |
| US5473070A (en) * | 1992-11-16 | 1995-12-05 | Cell Therapeutics, Inc. | Substituted long chain alcohol xanthine compounds |
| US6469017B1 (en) * | 1998-01-16 | 2002-10-22 | Cell Therapeutics, Inc. | Method of inhibiting interleukin-12 signaling |
| GB9312853D0 (en) * | 1993-06-22 | 1993-08-04 | Euro Celtique Sa | Chemical compounds |
| US5446046A (en) * | 1993-10-28 | 1995-08-29 | University Of Florida Research Foundation | A1 adenosine receptor agonists and antagonists as diuretics |
| US5736528A (en) * | 1993-10-28 | 1998-04-07 | University Of Florida Research Foundation, Inc. | N6 -(epoxynorborn-2-yl) adenosines as A1 adenosine receptor agonists |
| US5922751A (en) * | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
| US5591776A (en) * | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
| ATE247655T1 (de) * | 1994-12-13 | 2003-09-15 | Euro Celtique Sa | Dreifachsubstituierte thioxanthine |
| EP0814809B1 (en) * | 1994-12-13 | 2003-08-13 | Euroceltique S.A. | Aryl thioxanthines |
| US6166041A (en) * | 1995-10-11 | 2000-12-26 | Euro-Celtique, S.A. | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma |
| US6075016A (en) * | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
| US5864037A (en) * | 1996-06-06 | 1999-01-26 | Euro-Celtique, S.A. | Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity |
| US5789416B1 (en) * | 1996-08-27 | 1999-10-05 | Cv Therapeutics Inc | N6 mono heterocyclic substituted adenosine derivatives |
| US6576619B2 (en) | 1999-05-24 | 2003-06-10 | Cv Therapeutics, Inc. | Orally active A1 adenosine receptor agonists |
| CN1482913A (zh) * | 2000-09-08 | 2004-03-17 | CV���ƹ�˾ | 作为抗心律失常药的嘌呤核苷 |
| JP4483683B2 (ja) | 2005-04-28 | 2010-06-16 | 日立工機株式会社 | 連ねじドライバ |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2575344A (en) * | 1946-03-01 | 1951-11-20 | State Of Iowa | Dihydroxypropyl theophylline |
| US2517410A (en) * | 1947-08-15 | 1950-08-01 | Searle & Co | Hydroxy alkyl xanthines and the production thereof |
| DE2335170C2 (de) * | 1973-07-11 | 1989-07-20 | Hoechst Ag, 6230 Frankfurt | 1,3-Dialkyl-7-(hydroxyalkyl)-xanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| DE1911279A1 (de) * | 1969-03-05 | 1970-11-12 | Eckert Dr Theodor | Verfahren zur Erhoehung der Resorptionsfaehigkeit von Arzneistoffen |
| US4031218A (en) * | 1976-04-28 | 1977-06-21 | Mallinckrodt, Inc. | 7-(2,3-Dihydroxypropyl-1,3-di-n-propylxanthine and a pharmaceutical composition containing same useful as a bronchial muscle relaxant |
| US4397779A (en) * | 1978-08-09 | 1983-08-09 | Baxter Travenol Laboratories, Inc. | Preparation of xanthine tracers |
| IL59664A0 (en) * | 1979-04-05 | 1980-06-30 | Wuelfing J Kg | Xanthine derivatives,process for their preparation and their use in pharmaceutical compositions |
| IT1195267B (it) * | 1980-04-15 | 1988-10-12 | Abc Ist Biolog Chem Spa | Derivati teofillinmetildiossolanici,procedimento per la loro preparazione e relative composizioni farmaceutiche |
-
1981
- 1981-09-26 DE DE19813138397 patent/DE3138397A1/de not_active Withdrawn
-
1982
- 1982-09-17 US US06/420,932 patent/US4616020A/en not_active Expired - Lifetime
- 1982-09-22 EP EP82108751A patent/EP0075850B1/de not_active Expired
- 1982-09-22 AT AT82108751T patent/ATE17005T1/de not_active IP Right Cessation
- 1982-09-22 DE DE8282108751T patent/DE3268041D1/de not_active Expired
- 1982-09-23 PT PT75604A patent/PT75604B/pt unknown
- 1982-09-23 FI FI823274A patent/FI73681C/fi not_active IP Right Cessation
- 1982-09-24 DK DK426982A patent/DK148844C/da not_active IP Right Cessation
- 1982-09-24 KR KR8204320A patent/KR880002300B1/ko not_active Expired
- 1982-09-24 GR GR69358A patent/GR76734B/el unknown
- 1982-09-24 IL IL66864A patent/IL66864A0/xx not_active IP Right Cessation
- 1982-09-24 ZA ZA827012A patent/ZA827012B/xx unknown
- 1982-09-24 JP JP57165147A patent/JP2550301B2/ja not_active Expired - Lifetime
- 1982-09-24 ES ES515936A patent/ES8606346A1/es not_active Expired
- 1982-09-24 HU HU823086A patent/HU186125B/hu not_active IP Right Cessation
- 1982-09-24 NO NO823239A patent/NO158678C/no unknown
- 1982-09-24 IE IE2322/82A patent/IE53911B1/en not_active IP Right Cessation
- 1982-09-24 AU AU88663/82A patent/AU554227B2/en not_active Ceased
- 1982-09-24 CA CA000412172A patent/CA1286292C/en not_active Expired - Fee Related
-
1983
- 1983-12-16 ES ES528122A patent/ES8406479A1/es not_active Expired
- 1983-12-16 ES ES528123A patent/ES8407048A1/es not_active Expired
-
1986
- 1986-04-04 US US06/848,139 patent/US4713455A/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES528122A0 (es) | Procedimiento de preparacion de derivados de yantina como divisional de la solicitud de patente de invencion numero 515.936,solicitada el 24 de septiembre de 1982)(como divisional de la patente numero 515.936) | |
| ES2107866T3 (es) | Compuestos de (5,6)-dihidronaftalenilo sustituidos con actividad retinoide. | |
| IL83905A (en) | Substituted phenylalkylamines, their preparation and psychostimulating pharmaceutical compositions comprising same | |
| ES537300A0 (es) | Procedimiento para la preparacion de gangliosidos y sus derivados administrables por nebulizacion | |
| ES2051834T3 (es) | El uso de tetrahidrobenzeno(c,d)indol-6 carboxamidas para la preparacion de un medicamento para el tratamiento de la ansiedad. | |
| SE8700714D0 (sv) | Anvendning av substituerade 4-fenyl-4-oxo-2-butensyraderivat for framstellning av lekemedel for behandling av sjukdomar i matsmeltningskanalen och som antiulcerost lekemedel | |
| ES2053668T3 (es) | Derivados de poliamina como agentes antineoplasicos. | |
| SE8500996D0 (sv) | Method of treatment | |
| FR2445330A1 (fr) | Derives du 11-bromo-14,15-dioxo-e-homo-eburnane leur preparation et leur utilisation comme medicament | |
| IL79910A (en) | 5,7-dihydro-6-(thi)oxopyrrolo(2,3-f)benzimidazole,-benzothiazole and-benzoxazoles,6-imines thereof,their preparation and pharmaceutical compositions containing them | |
| ES2059348T3 (es) | Composicion farmaceutica para el tratamiento de cataratas. | |
| FR2379532A1 (fr) | Nouveaux derives de l'acide oxamique, leur preparation et leur application comme medicaments | |
| KR910015301A (ko) | 수면 무호흡증의 치료방법 | |
| KR880013562A (ko) | 7-티아프로스타글란딘e₁ 또는 그의 유도체를 함유하는 당뇨병치료 조성물 | |
| FR2448544A1 (fr) | Derives de thiazole et leur application en therapeutique | |
| SE8005309L (sv) | Nya 5alfa-pregnan-20-ol-derivat och salter derav med syror, sett for framstellning samt anvendning derav sasom lekemedel samt kompositioner innehallande dessa foreningar | |
| FR2391992A1 (fr) | Nouveaux derives du benzocycloheptene, leur preparation et leur application comme medicaments | |
| FR2432507A1 (fr) | Nouveaux sels de sulfonium, leur preparation et leur application comme medicaments | |
| SE8306884D0 (sv) | Akrylsyraderivat innehallande en syrehaltig heterocykel till anvendning som lekemedel, nya industriprodukter och framstellningsforfarande | |
| FR2401923A1 (fr) | Nouvelles octahydropyrazinopyrimidinones 2,3,4,7,8,9-substituees, procede de preparation de ces derives et leur application en tant que medicaments |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20041102 |