ES497425A0 - Un metodo de preparacion de un anticuerpo monoclonal. - Google Patents

Un metodo de preparacion de un anticuerpo monoclonal.

Info

Publication number: ES497425A0
Authority: ES; Spain
Prior art keywords: monoclonal antibody; preparing; hybrid; caf; immunized
Prior art date: 1979-12-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES497425A

Other languages

English (en)

Other versions

ES8303097A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Ortho Pharmaceutical Corp

Original Assignee

Ortho Pharmaceutical Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-12-04

Filing date

1980-12-03

Publication date

1982-12-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22277974&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES497425(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1980-12-03 Application filed by Ortho Pharmaceutical Corp filed Critical Ortho Pharmaceutical Corp

1982-12-16 Publication of ES497425A0 publication Critical patent/ES497425A0/es

1983-02-16 Publication of ES8303097A1 publication Critical patent/ES8303097A1/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hybrid Cells (AREA)

ES497425A 1979-12-04 1980-12-03 Un metodo de preparacion de un anticuerpo monoclonal. Expired ES8303097A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/100,072 US4364935A (en)	1979-12-04	1979-12-04	Monoclonal antibody to a human prothymocyte antigen and methods of preparing same

Publications (2)

Publication Number	Publication Date
ES497425A0 true ES497425A0 (es)	1982-12-16
ES8303097A1 ES8303097A1 (es)	1983-02-16

Family

ID=22277974

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES497425A Expired ES8303097A1 (es)	1979-12-04	1980-12-03	Un metodo de preparacion de un anticuerpo monoclonal.

Country Status (22)

Country	Link
US (1)	US4364935A (es)
EP (1)	EP0030815B1 (es)
JP (2)	JPS5695123A (es)
AT (1)	ATE13317T1 (es)
AU (1)	AU545223B2 (es)
CA (1)	CA1183470A (es)
DE (2)	DE3070655D1 (es)
DK (1)	DK153954C (es)
ES (1)	ES8303097A1 (es)
FI (1)	FI75365C (es)
GR (1)	GR72923B (es)
HK (1)	HK24386A (es)
IE (1)	IE50725B1 (es)
IL (1)	IL61624A (es)
MY (1)	MY8600519A (es)
NO (1)	NO159888C (es)
NZ (1)	NZ195647A (es)
PH (1)	PH17510A (es)
PT (1)	PT72146B (es)
SG (1)	SG7386G (es)
YU (1)	YU45078B (es)
ZA (1)	ZA807567B (es)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
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US4806349A (en) *	1979-12-04	1989-02-21	Ortho Pharmaceutical Corporation	Hybrid cell line for producing monoclonal antibody to a human prothymocyte antigen, antibody, and methods
US4582797A (en) *	1980-09-25	1986-04-15	The Salk Institute For Biological Studies	Monoclonal antibodies specific for human hematopoietic cell surface glycoproteins
JPS5823847B2 (ja) *	1981-02-06	1983-05-18	株式会社林原生物化学研究所	抗ヒト蛋白質抗体の製造方法
DE3105150A1 (de) *	1981-02-12	1982-08-19	Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG, 6380 Bad Homburg	Herstellung von anti-t-lymphozyten-globulin.
US4434156A (en)	1981-10-26	1984-02-28	The Salk Institute For Biological Studies	Monoclonal antibodies specific for the human transferrin receptor glycoprotein
USRE32011E (en) *	1981-12-14	1985-10-22	Scripps Clinic And Research Foundation	Ultrapurification of factor VIII using monoclonal antibodies
EP0103632B1 (en) *	1982-03-15	1990-12-19	The Trustees Of Columbia University In The City Of New York	Method for introducing cloned, amplifiable genes into eucaryotic cells and for producing proteinaceous products
US4443427A (en) *	1982-06-21	1984-04-17	Sidney Farber Cancer Institute, Inc.	Monoclonal antibody
US4579827A (en) *	1983-03-11	1986-04-01	Sloan-Kettering Institute For Cancer Research	Monoclonal antibodies to human gastrointestinal cancers and hybridoma method of production of the monoclonal antibodies
JPS60231699A (ja) *	1983-11-09	1985-11-18	Aichiken	正常及び悪性ヒト造血器細胞に対するモノクローナル抗体
FR2560212B1 (fr) *	1984-02-24	1989-12-29	Unicet	Anticorps monoclonaux contre l'interferon a2 et hybridomes produisant de tels anticorps
US5431897A (en) *	1985-04-19	1995-07-11	Sloan-Kettering Institute For Cancer Research	Method of imaging colorectal carcinoma lesion and composition for use therein
US4705687A (en) *	1985-06-17	1987-11-10	Ortho Pharmaceutical (Canada) Ltd.	Treatment of autoimmune diseases such as rheumatoid arthritis with suppressor factor
US4970299A (en) *	1986-07-03	1990-11-13	Sloan-Kettering Institute For Cancer Research	Monoclonal antibodies selective for prostate cancer
US5601819A (en) *	1988-08-11	1997-02-11	The General Hospital Corporation	Bispecific antibodies for selective immune regulation and for selective immune cell binding
CA2310805A1 (en) *	1997-11-24	1999-06-03	Johnson T. Wong	Methods for treatment of hiv or other infections using a t cell or viral activator and anti-retroviral combination therapy
FR2878852B1 (fr) *	2000-09-28	2007-02-23	Imtix Sangstat	Procede de production d'immunoglobulines anti-thymocytes humains
US7653260B2 (en)	2004-06-17	2010-01-26	Carl Zeis MicroImaging GmbH	System and method of registering field of view
US8582924B2 (en)	2004-06-30	2013-11-12	Carl Zeiss Microimaging Gmbh	Data structure of an image storage and retrieval system
US9486524B2 (en) *	2006-09-01	2016-11-08	Genticel	Composition for eliciting a specific CTL response, comprising a lympho-ablative compound and a molecule that contains antigenic sequences and targets professional antigen presenting cells
WO2011028952A1 (en)	2009-09-02	2011-03-10	Xencor, Inc.	Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
AU2011283694B2 (en)	2010-07-29	2017-04-13	Xencor, Inc.	Antibodies with modified isoelectric points
US12466897B2 (en)	2011-10-10	2025-11-11	Xencor, Inc.	Heterodimeric human IgG1 polypeptides with isoelectric point modifications
US10851178B2 (en)	2011-10-10	2020-12-01	Xencor, Inc.	Heterodimeric human IgG1 polypeptides with isoelectric point modifications
US10131710B2 (en)	2013-01-14	2018-11-20	Xencor, Inc.	Optimized antibody variable regions
US10738132B2 (en)	2013-01-14	2020-08-11	Xencor, Inc.	Heterodimeric proteins
US11053316B2 (en)	2013-01-14	2021-07-06	Xencor, Inc.	Optimized antibody variable regions
US9605084B2 (en)	2013-03-15	2017-03-28	Xencor, Inc.	Heterodimeric proteins
US9701759B2 (en)	2013-01-14	2017-07-11	Xencor, Inc.	Heterodimeric proteins
US10487155B2 (en)	2013-01-14	2019-11-26	Xencor, Inc.	Heterodimeric proteins
US10968276B2 (en)	2013-03-12	2021-04-06	Xencor, Inc.	Optimized anti-CD3 variable regions
US9738722B2 (en)	2013-01-15	2017-08-22	Xencor, Inc.	Rapid clearance of antigen complexes using novel antibodies
US10106624B2 (en)	2013-03-15	2018-10-23	Xencor, Inc.	Heterodimeric proteins
EP3421495A3 (en)	2013-03-15	2019-05-15	Xencor, Inc.	Modulation of t cells with bispecific antibodies and fc fusions
US10519242B2 (en)	2013-03-15	2019-12-31	Xencor, Inc.	Targeting regulatory T cells with heterodimeric proteins
US10858417B2 (en)	2013-03-15	2020-12-08	Xencor, Inc.	Heterodimeric proteins
US10675352B2 (en)	2014-02-14	2020-06-09	Centrose, Llc	Extracellular targeted drug conjugates
LT3122781T (lt)	2014-03-28	2020-03-25	Xencor, Inc.	Bispecifiniai antikūnai, kurie jungiasi prie cd38 ir cd3
US10259887B2 (en)	2014-11-26	2019-04-16	Xencor, Inc.	Heterodimeric antibodies that bind CD3 and tumor antigens
TN2017000223A1 (en)	2014-11-26	2018-10-19	Xencor Inc	Heterodimeric antibodies that bind cd3 and tumor antigens
IL252467B (en)	2014-11-26	2022-06-01	Xencor Inc	Heterodimeric antibodies that bind cd3 and cd38
US10428155B2 (en)	2014-12-22	2019-10-01	Xencor, Inc.	Trispecific antibodies
US10227411B2 (en)	2015-03-05	2019-03-12	Xencor, Inc.	Modulation of T cells with bispecific antibodies and FC fusions
KR20180085800A (ko)	2015-12-07	2018-07-27	젠코어 인코포레이티드	Cd3 및 psma에 결합하는 이종이합체성 항체
MA45255A (fr)	2016-06-14	2019-04-17	Xencor Inc	Anticorps inhibiteurs de points de contrôle bispécifiques
CA3029328A1 (en)	2016-06-28	2018-01-04	Xencor, Inc.	Heterodimeric antibodies that bind somatostatin receptor 2
US10793632B2 (en)	2016-08-30	2020-10-06	Xencor, Inc.	Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
JP7142630B2 (ja)	2016-10-14	2022-09-27	ゼンコアインコーポレイテッド	ＩＬ１５／ＩＬ１５Ｒαヘテロ二量体ＦＣ－融合タンパク質
AU2018291497A1 (en)	2017-06-30	2020-01-16	Xencor, Inc.	Targeted heterodimeric Fc fusion proteins containing IL-15/IL-15Ra and antigen binding domains
US11312770B2 (en)	2017-11-08	2022-04-26	Xencor, Inc.	Bispecific and monospecific antibodies using novel anti-PD-1 sequences
US10981992B2 (en)	2017-11-08	2021-04-20	Xencor, Inc.	Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
JP7765181B2 (ja)	2017-12-19	2025-11-06	ゼンコアインコーポレイテッド	改変されたｉｌ－２ｆｃ融合タンパク質
US10982006B2 (en)	2018-04-04	2021-04-20	Xencor, Inc.	Heterodimeric antibodies that bind fibroblast activation protein
CA3097741A1 (en)	2018-04-18	2019-10-24	Xencor, Inc.	Tim-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and tim-3 antigen binding domains
CN112867734A (zh)	2018-04-18	2021-05-28	Xencor股份有限公司	包含IL-15/IL-15Ra Fc融合蛋白和PD-1抗原结合结构域的靶向PD-1的异源二聚体融合蛋白及其用途
AU2019355971B2 (en)	2018-10-03	2025-05-08	Xencor, Inc.	IL-12 heterodimeric Fc-fusion proteins
BR112021016955A2 (pt)	2019-03-01	2021-11-23	Xencor Inc	Composição, composição de ácido nucleico, composição de vetor de expressão, vetor de expressão, célula hospedeira, métodos de produção de um domínio de ligação de membro de família 3 de pirofosfatase/fosfodiesterase de ectonucleotídeo e de tratamento de um câncer, anticorpo anti-enpp3, e, anticorpo heterodimérico
US11919956B2 (en)	2020-05-14	2024-03-05	Xencor, Inc.	Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3
US11739144B2 (en)	2021-03-09	2023-08-29	Xencor, Inc.	Heterodimeric antibodies that bind CD3 and CLDN6
KR20230154311A (ko)	2021-03-10	2023-11-07	젠코어 인코포레이티드	Cd3 및 gpc3에 결합하는 이종이량체 항체
CN114085818A (zh) *	2021-11-19	2022-02-25	蔡开来	一种抗大熊猫Thy1单克隆抗体及其杂交瘤细胞株和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4196265A (en) *	1977-06-15	1980-04-01	The Wistar Institute	Method of producing antibodies
US4172124A (en) *	1978-04-28	1979-10-23	The Wistar Institute	Method of producing tumor antibodies
US4284412A (en) *	1979-07-13	1981-08-18	Ortho Diagnostics, Inc.	Method and apparatus for automated identification and enumeration of specified blood cell subclasses

1979
- 1979-12-04 US US06/100,072 patent/US4364935A/en not_active Expired - Lifetime
1980
- 1980-11-21 CA CA000365175A patent/CA1183470A/en not_active Expired
- 1980-11-25 NZ NZ195647A patent/NZ195647A/en unknown
- 1980-12-02 GR GR63536A patent/GR72923B/el unknown
- 1980-12-03 FI FI803757A patent/FI75365C/fi not_active IP Right Cessation
- 1980-12-03 AU AU65012/80A patent/AU545223B2/en not_active Expired
- 1980-12-03 PH PH24938A patent/PH17510A/en unknown
- 1980-12-03 DE DE8080304350T patent/DE3070655D1/de not_active Expired
- 1980-12-03 ES ES497425A patent/ES8303097A1/es not_active Expired
- 1980-12-03 PT PT72146A patent/PT72146B/pt unknown
- 1980-12-03 EP EP80304350A patent/EP0030815B1/en not_active Expired
- 1980-12-03 IL IL61624A patent/IL61624A/xx not_active IP Right Cessation
- 1980-12-03 IE IE2511/80A patent/IE50725B1/en not_active IP Right Cessation
- 1980-12-03 NO NO803661A patent/NO159888C/no not_active IP Right Cessation
- 1980-12-03 DK DK517380A patent/DK153954C/da not_active IP Right Cessation
- 1980-12-03 ZA ZA00807567A patent/ZA807567B/xx unknown
- 1980-12-03 AT AT80304350T patent/ATE13317T1/de not_active IP Right Cessation
- 1980-12-03 YU YU3067/80A patent/YU45078B/xx unknown
- 1980-12-03 DE DE198080304350T patent/DE30815T1/de active Pending
- 1980-12-04 JP JP17032780A patent/JPS5695123A/ja active Granted
1986
- 1986-01-23 SG SG73/86A patent/SG7386G/en unknown
- 1986-04-03 HK HK243/86A patent/HK24386A/en not_active IP Right Cessation
- 1986-12-30 MY MY519/86A patent/MY8600519A/xx unknown
1988
- 1988-05-17 JP JP63118392A patent/JPS6413988A/ja active Granted

Also Published As

Publication number	Publication date
US4364935A (en)	1982-12-21
NZ195647A (en)	1984-07-06
FI75365C (fi)	1988-06-09
NO159888B (no)	1988-11-07
GR72923B (es)	1984-01-11
YU306780A (en)	1984-04-30
FI803757L (fi)	1981-06-05
HK24386A (en)	1986-04-11
IE50725B1 (en)	1986-06-25
EP0030815B1 (en)	1985-05-15
DE3070655D1 (en)	1985-06-20
JPS649999B2 (es)	1989-02-21
FI75365B (fi)	1988-02-29
PH17510A (en)	1984-09-07
EP0030815A3 (en)	1981-12-30
AU6501280A (en)	1981-06-11
CA1183470A (en)	1985-03-05
NO803661L (no)	1981-06-05
DK517380A (da)	1981-06-05
IL61624A (en)	1984-07-31
MY8600519A (en)	1986-12-31
JPS6413988A (en)	1989-01-18
AU545223B2 (en)	1985-07-04
ES8303097A1 (es)	1983-02-16
ATE13317T1 (de)	1985-06-15
DK153954C (da)	1989-02-20
DK153954B (da)	1988-09-26
SG7386G (en)	1986-11-21
PT72146A (en)	1981-01-01
YU45078B (en)	1992-03-10
DE30815T1 (de)	1984-07-19
PT72146B (en)	1982-07-05
JPS5695123A (en)	1981-08-01
JPH0159870B2 (es)	1989-12-20
IE802511L (en)	1981-06-04
IL61624A0 (en)	1981-01-30
NO159888C (no)	1989-02-15
ZA807567B (en)	1982-07-28
EP0030815A2 (en)	1981-06-24

Publication	Publication Date	Title
ES497425A0 (es)	1982-12-16	Un metodo de preparacion de un anticuerpo monoclonal.
ES498360A0 (es)	1982-12-16	Un metodo de preparacion de un anticuerpo monoclonal.
ES490943A0 (es)	1981-05-16	Un metodo para la preparacion de un anticuerpo monoclonico.
ES497422A0 (es)	1982-12-16	Un metodo de preparacion de un inticuerpo monocloral.
ES489757A0 (es)	1981-04-16	Un metodo para la preparacion de un anticuerpo monoclonico.
ES497424A0 (es)	1983-01-01	Un metodo de preparacion de un anticuerpo monoclonal.
ES497423A0 (es)	1982-12-16	Un anticuerpo monoclonico