ES496167A0 - Perfeccionamientos en o relacionados con compuestos organi- cos - Google Patents
Perfeccionamientos en o relacionados con compuestos organi- cosInfo
- Publication number
- ES496167A0 ES496167A0 ES496167A ES496167A ES496167A0 ES 496167 A0 ES496167 A0 ES 496167A0 ES 496167 A ES496167 A ES 496167A ES 496167 A ES496167 A ES 496167A ES 496167 A0 ES496167 A0 ES 496167A0
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- optionally
- alkyl
- hydroxy
- aralkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7907800A NL7907800A (nl) | 1979-10-23 | 1979-10-23 | Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8106894A1 ES8106894A1 (es) | 1981-09-16 |
| ES496167A0 true ES496167A0 (es) | 1981-09-16 |
Family
ID=19834064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES496167A Granted ES496167A0 (es) | 1979-10-23 | 1980-10-22 | Perfeccionamientos en o relacionados con compuestos organi- cos |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US4425353A (es) |
| EP (1) | EP0028717B1 (es) |
| JP (1) | JPS5686164A (es) |
| AT (1) | ATE8990T1 (es) |
| AU (1) | AU539310B2 (es) |
| CA (1) | CA1155840A (es) |
| DE (1) | DE3068961D1 (es) |
| DK (1) | DK435380A (es) |
| ES (1) | ES496167A0 (es) |
| FI (1) | FI67373C (es) |
| IE (1) | IE50667B1 (es) |
| IL (1) | IL61324A (es) |
| MY (1) | MY8700184A (es) |
| NL (1) | NL7907800A (es) |
| NZ (1) | NZ195329A (es) |
| PT (1) | PT71949B (es) |
| ZA (1) | ZA806528B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4579950A (en) * | 1982-08-20 | 1986-04-01 | Hoechst-Roussel Pharmaceuticals Inc. | Intermediates for spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine] compounds |
| JPH01102077A (ja) * | 1987-09-24 | 1989-04-19 | Hoechst Roussel Pharmaceut Inc | 2,6‐メタノピロロ‐3‐ベンズアゾジン類 |
| DE4121821A1 (de) * | 1991-07-02 | 1993-01-14 | Boehringer Ingelheim Kg | Neue benzomorphane und ihre verwendung als arzneimittel |
| DE19528472A1 (de) * | 1995-08-03 | 1997-02-06 | Boehringer Ingelheim Kg | Neues Verfahren zur Herstellung von Norbenzomorphan einer Zwischenstufe bei Herstellung von pharmazeutisch wertvollen Benzomorphanderivaten, insbesondere von (-)-(1R,5S,S"R)-3'-Hydroxy-2-(2-methoxypropyl-)-5,9,9-trimethyl-6,7 benzomorphan |
| AU9621598A (en) | 1997-10-20 | 1999-05-10 | Novo Nordisk A/S | Luteinising hormone antagonists useful for treatment of estrogen deficiencies, or as a contraceptive |
| US6136980A (en) * | 1998-05-01 | 2000-10-24 | Boehringer Ingelheim Kg | Method of preparing norbenzomorphane as an intermediate in the preparation of pharmaceutically useful benzomorphane derivatives, in particular (-)-(1R,5S,2"R)-3'-hydroxy-2-(2-methoxypropyl)-5,9,9-trimethyl-6,7-benzo morphane |
| AU3885901A (en) * | 1999-09-21 | 2001-04-24 | Emory University | Methods and compositions for treating platelet-related disorders |
| US6495694B2 (en) * | 2000-06-16 | 2002-12-17 | Boehringer Ingelheim Pharma Kg | Efficient separation of enantiomers of piperidone derivatives by precipitation of the desired eantiomer during in situ racemization of the unwanted enantiomer |
| WO2013167963A1 (en) | 2012-05-11 | 2013-11-14 | Purdue Pharma L.P. | Benzomorphan compounds as opioid receptors modulators |
| CA2890655A1 (en) | 2012-11-09 | 2014-05-15 | Purdue Pharma L.P. | Benzomorphan analogs and the use thereof |
| US9056836B2 (en) | 2013-01-31 | 2015-06-16 | Purdue Pharma L.P. | Benzomorphan analogs and the use thereof |
| MA39956A (fr) | 2014-05-06 | 2015-11-12 | Purdue Pharma Lp | Analogues du benzomorphane et leur utilisation |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL130089C (es) | 1963-11-07 | |||
| US4087532A (en) | 1974-03-09 | 1978-05-02 | Boehringer Ingelheim Gmbh | Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof |
| GB1513961A (en) * | 1975-02-25 | 1978-06-14 | Acf Chemiefarma Nv | 6,7-benzomorphans method for their preparation and intermediates |
| DE2716687A1 (de) | 1977-04-15 | 1978-10-19 | Boehringer Sohn Ingelheim | 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel |
| US4202897A (en) * | 1977-07-25 | 1980-05-13 | Sandoz, Inc. | Prolactin secretion inhibitors |
| IT8049377A0 (it) | 1979-08-03 | 1980-07-30 | Sandoz Ag | Medicamento a base di composti triciclici per inibire la secrezione dell'ormone luteinizzante(caso 1005224) |
-
1979
- 1979-10-23 NL NL7907800A patent/NL7907800A/nl not_active Application Discontinuation
-
1980
- 1980-10-13 DE DE8080106213T patent/DE3068961D1/de not_active Expired
- 1980-10-13 EP EP80106213A patent/EP0028717B1/en not_active Expired
- 1980-10-13 AT AT80106213T patent/ATE8990T1/de active
- 1980-10-14 DK DK435380A patent/DK435380A/da not_active Application Discontinuation
- 1980-10-14 FI FI803237A patent/FI67373C/fi not_active IP Right Cessation
- 1980-10-21 CA CA000362879A patent/CA1155840A/en not_active Expired
- 1980-10-21 AU AU63540/80A patent/AU539310B2/en not_active Ceased
- 1980-10-21 IL IL61324A patent/IL61324A/xx unknown
- 1980-10-21 NZ NZ195329A patent/NZ195329A/en unknown
- 1980-10-22 IE IE2188/80A patent/IE50667B1/en unknown
- 1980-10-22 ES ES496167A patent/ES496167A0/es active Granted
- 1980-10-22 JP JP14887180A patent/JPS5686164A/ja active Pending
- 1980-10-22 PT PT71949A patent/PT71949B/pt unknown
- 1980-10-23 ZA ZA00806528A patent/ZA806528B/xx unknown
-
1981
- 1981-07-13 US US06/282,799 patent/US4425353A/en not_active Expired - Fee Related
- 1981-07-13 US US06/283,084 patent/US4406904A/en not_active Expired - Fee Related
-
1987
- 1987-12-30 MY MY184/87A patent/MY8700184A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3068961D1 (en) | 1984-09-20 |
| FI803237L (fi) | 1981-04-24 |
| FI67373B (fi) | 1984-11-30 |
| NZ195329A (en) | 1984-05-31 |
| ES8106894A1 (es) | 1981-09-16 |
| US4406904A (en) | 1983-09-27 |
| EP0028717B1 (en) | 1984-08-15 |
| EP0028717A1 (en) | 1981-05-20 |
| IL61324A (en) | 1985-03-31 |
| JPS5686164A (en) | 1981-07-13 |
| MY8700184A (en) | 1987-12-31 |
| PT71949A (en) | 1981-08-19 |
| IE802188L (en) | 1981-04-23 |
| IE50667B1 (en) | 1986-06-11 |
| DK435380A (da) | 1981-04-24 |
| CA1155840A (en) | 1983-10-25 |
| PT71949B (en) | 1981-12-17 |
| AU539310B2 (en) | 1984-09-20 |
| AU6354080A (en) | 1981-04-30 |
| US4425353A (en) | 1984-01-10 |
| NL7907800A (nl) | 1981-04-27 |
| ATE8990T1 (de) | 1984-09-15 |
| IL61324A0 (en) | 1980-12-31 |
| ZA806528B (en) | 1982-06-30 |
| FI67373C (fi) | 1985-03-11 |
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