[go: up one dir, main page]

ES446075A1 - A PROCEDURE FOR THE PREPARATION OF ORAL DOSAGE UNITS WITH PROLONGED RELEASE OF THE THERAPEUTICALLY ACTIVE COMPONENT. - Google Patents

A PROCEDURE FOR THE PREPARATION OF ORAL DOSAGE UNITS WITH PROLONGED RELEASE OF THE THERAPEUTICALLY ACTIVE COMPONENT.

Info

Publication number
ES446075A1
ES446075A1 ES446075A ES446075A ES446075A1 ES 446075 A1 ES446075 A1 ES 446075A1 ES 446075 A ES446075 A ES 446075A ES 446075 A ES446075 A ES 446075A ES 446075 A1 ES446075 A1 ES 446075A1
Authority
ES
Spain
Prior art keywords
procedure
preparation
active component
oral dosage
therapeutically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES446075A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Priority claimed from KR7600645A external-priority patent/KR800001387B1/en
Publication of ES446075A1 publication Critical patent/ES446075A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus

Landscapes

  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Solid pharmaceutical formulations are described which have a sustained release effect and which are buoyant in gastric juice. The formulation is present in the form of a homogeneous mixture. This mixture contains at least one therapeutic active compound, up to 80% by weight of therapeutically inert, pharmaceutically acceptable auxiliary substances, up to 60% by weight of a fatty material having a specific weight less than 1 and such a proportion of a hydrocolloid or of a mixture of hydrocolloids, incorporated into the formulation essentially in the dry form, that, after contact with the gastric juice, a layer which is impermeable to water is generated on the surface of this homogeneous mixture.
ES446075A 1975-03-17 1976-03-16 A PROCEDURE FOR THE PREPARATION OF ORAL DOSAGE UNITS WITH PROLONGED RELEASE OF THE THERAPEUTICALLY ACTIVE COMPONENT. Expired ES446075A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US55910775A 1975-03-17 1975-03-17
US65800376A 1976-02-13 1976-02-13
KR7600645A KR800001387B1 (en) 1975-03-17 1976-03-16 Process for preparing sustained release formulation

Publications (1)

Publication Number Publication Date
ES446075A1 true ES446075A1 (en) 1977-09-16

Family

ID=27348140

Family Applications (1)

Application Number Title Priority Date Filing Date
ES446075A Expired ES446075A1 (en) 1975-03-17 1976-03-16 A PROCEDURE FOR THE PREPARATION OF ORAL DOSAGE UNITS WITH PROLONGED RELEASE OF THE THERAPEUTICALLY ACTIVE COMPONENT.

Country Status (21)

Country Link
JP (1) JPS51115910A (en)
AR (1) AR222624A1 (en)
AT (1) AT353415B (en)
AU (1) AU505355B2 (en)
CA (1) CA1073358A (en)
CH (1) CH630257A5 (en)
DD (1) DD124102A5 (en)
DE (1) DE2611041A1 (en)
DK (1) DK148344C (en)
ES (1) ES446075A1 (en)
FR (1) FR2304354A1 (en)
GB (1) GB1546448A (en)
GR (1) GR60341B (en)
IE (1) IE43083B1 (en)
LU (1) LU74558A1 (en)
MC (1) MC1101A1 (en)
NL (1) NL190313C (en)
NZ (1) NZ180321A (en)
PH (1) PH14927A (en)
PT (1) PT64907B (en)
SE (1) SE433804B (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ197543A (en) * 1980-07-02 1984-12-14 Commw Scient Ind Res Org Controlled release compositions for inclusion in intraruminal devices
CH649215A5 (en) * 1981-04-29 1985-05-15 Hoffmann La Roche PHARMACEUTICAL PREPARATIONS.
CH652025A5 (en) * 1981-09-14 1985-10-31 Hoffmann La Roche Pharmaceutical preparation.
US4421736A (en) * 1982-05-20 1983-12-20 Merrel Dow Pharmaceuticals Inc. Sustained release diethylpropion compositions
GB2154874B (en) * 1984-02-29 1987-11-04 Sandoz Ltd Bromoscriptine compositions
CH666406A5 (en) * 1984-02-29 1988-07-29 Sandoz Ag METHOD FOR PRODUCING microcapsules BROMOKRIPTINMESYLAT AS PHARMACOLOGICAL ACTIVE INCLUDED.
AU4064285A (en) * 1984-03-21 1985-10-11 American Home Products Corporation Sustained release pharmaceutical capsules
JPS6143108A (en) * 1984-08-03 1986-03-01 Nippon Shinyaku Co Ltd Medicinal drug and its preparation
HU195729B (en) * 1985-02-05 1988-07-28 Sandoz Ag Process for producing pharmaceutical compositions containing 9,10-dihydro-ergot-alkaloides
GB8524135D0 (en) * 1985-10-01 1985-11-06 Sandoz Ltd Darodipine compositions
NL194822C (en) * 1985-10-01 2003-04-03 Novartis Ag Preparation for oral administration with controlled release and method for its preparation.
US4786503A (en) * 1987-04-06 1988-11-22 Alza Corporation Dosage form comprising parallel lamine
US4814178A (en) * 1987-07-01 1989-03-21 Sanford Bolton Floating sustained release therapeutic compositions
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
IE64128B1 (en) * 1990-02-26 1995-07-12 Byrne Rynne Holdings Ltd A pharmaceutical composition
UA37214C2 (en) * 1991-01-30 2001-05-15 Дзе Веллкам Фаундейшн Лімітед TABLETS DISPERSED IN WATER AND METHOD OF PREPARATION
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
JP2626248B2 (en) * 1991-04-08 1997-07-02 日本新薬株式会社 Capsule
ATE173159T1 (en) * 1992-03-25 1998-11-15 Depomed Systems Inc ORAL MEDICINAL DOSAGE FORMS BASED ON HYDROXYETHYL CELLULOSE WITH DELAYED RELEASE
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
WO1995011667A1 (en) * 1993-10-29 1995-05-04 R.P. Scherer Corporation Gelatin capsule fill able to foam
US5888540A (en) * 1993-10-29 1999-03-30 Sugden; Keith Pharmaceutical products
CA2174777A1 (en) * 1993-10-29 1995-05-04 Keith Sugden Gelatin capsule fill able to foam
US5919491A (en) * 1994-05-13 1999-07-06 Smithkline Beecham Corporation Method and composition for increasing calcium uptake
JPH10509981A (en) * 1994-12-01 1998-09-29 サイバス ファーマシューティカル，インコーポレイティド Sustained drug delivery using powdered hydrocolloid rubber obtainable from higher plants
FR2820319B3 (en) * 2001-02-08 2003-12-05 Ellipse Pharmaceuticals PROCESS FOR PRODUCING A FLOATING TABLET INCLUDING ALFUZOSINE AND TABLET OBTAINED
FR2820318B1 (en) * 2001-02-08 2005-12-23 Ellipse Pharmaceuticals METHOD FOR MANUFACTURING A FLOATING COMPRESSOR INCLUDING AN ACTIVE INGREDIENT AND A COMPRESS OBTAINED
EP1245227A1 (en) 2001-03-31 2002-10-02 Jagotec Ag A pharmaceutical tablet system that floats in the stomach for programmed release of active substance and process of producing buoyant material contained in same
FR2874325B1 (en) * 2004-08-19 2006-10-20 Sanofi Synthelabo PHARMACEUTICAL COMPOSITION IN THE FORM OF A GASTRIC RESISTANCE COMPRESSOR CONTAINING ALFUZOSIN
WO2026022379A1 (en) * 2024-07-26 2026-01-29 Inkvivo Technologies Sa Gastroretentive formulations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1059624B (en) * 1954-11-11 1959-06-18 Dr Knut Jacobus Sundman Process for the production of medicaments dispersed in a carrier substance in dosed form
JPS5512411B2 (en) * 1974-03-12 1980-04-02
DE2439538C3 (en) * 1974-08-17 1980-07-17 Ludwig Heumann & Co Gmbh, 8500 Nuernberg Process for the manufacture of orally administered drugs with delayed release of action

Also Published As

Publication number Publication date
DK113676A (en) 1976-09-18
PH14927A (en) 1982-01-29
GB1546448A (en) 1979-05-23
LU74558A1 (en) 1977-09-27
NL190313C (en) 1994-01-17
DE2611041A1 (en) 1976-10-14
DE2611041C2 (en) 1988-06-09
DD124102A5 (en) 1977-02-02
MC1101A1 (en) 1977-02-04
PT64907A (en) 1976-04-01
CH630257A5 (en) 1982-06-15
AR222624A1 (en) 1981-06-15
GR60341B (en) 1978-05-17
AT353415B (en) 1979-11-12
ATA192276A (en) 1979-04-15
IE43083L (en) 1976-09-17
NL190313B (en) 1993-08-16
NZ180321A (en) 1978-06-20
JPS51115910A (en) 1976-10-13
DK148344B (en) 1985-06-17
FR2304354B1 (en) 1979-04-27
SE433804B (en) 1984-06-18
IE43083B1 (en) 1980-12-17
DK148344C (en) 1985-11-04
PT64907B (en) 1978-03-24
AU1204976A (en) 1977-09-22
CA1073358A (en) 1980-03-11
JPS638084B2 (en) 1988-02-19
SE7603325L (en) 1976-09-18
NL7602776A (en) 1976-09-21
FR2304354A1 (en) 1976-10-15
AU505355B2 (en) 1979-11-15

Similar Documents

Publication Publication Date Title
ES446075A1 (en) A PROCEDURE FOR THE PREPARATION OF ORAL DOSAGE UNITS WITH PROLONGED RELEASE OF THE THERAPEUTICALLY ACTIVE COMPONENT.
ES8200558A1 (en) Pharmaceutical composition in the form of a polyacrylate film, and its preparation.
SE8303531D0 (en) PHARMACEUTICAL COMPOSITION
NO178095C (en) Process for the preparation of a wrapped pharmaceutical retarding composition
ES424533A1 (en) Slow release pharmaceutical compositions
DE3271829D1 (en) An allergen dry powder composition and process for its preparation
EP0350701A3 (en) Pharmaceutical cmpositions for oral administration having analgesic and anti-inflammatory activity, possessing excellent palatability and being free of irritating effects on mucous membranes
AR013506A1 (en) USE OF A PHARMACEUTICAL COMPOSITION FOR THE MANUFACTURE OF A MEDICINAL PRODUCT TO BE USED IN THE TREATMENT OF DISEASES OF PULMONARCHRONIC OBSTRUCTION AND OF A KIT INCLUDING FORMOTEROL OR A SALT OR SOLVATE OF THE SAME AND BUDESONIDE
AR031682A1 (en) PHARMACEUTICAL COMPOSITIONS
DK0724885T3 (en) Pernasal composition and pernasal preparation containing this
SE8001599L (en) TRANSDERMAL MEDICATION SYSTEM FOR ISOSORBID DINITRATE
IE791806L (en) Gastroprotective mollusc extract
KR910005858A (en) Fatty acid therapy
ES8400028A1 (en) PREPARATION METHOD OF AN ANHYDRA THIXOTROPIC COMPOSITION.
ES2078838A1 (en) PROCEDURE FOR PREPARING A CLOZAPINE BASED COMPOSITION.
DK78487D0 (en) PHARMACEUTICAL PREPARATION CONTAINING A WATER-INFLUENTING POLYMER MATERIAL
Axelsen et al. Papillary necrosis in the Gunn rat: Rapid induction by analgesics
JPS554397A (en) Novel n11benzoylln22phenyll1*33diaminopropane 22ol*its manufacture and medicine containing it for therapy of acute and chronic gastritis
DK0483320T3 (en) Prolonged-release pharmaceutical compositions for oral administration and methods for their preparation
GB976096A (en) Pharmaceutical compositions
MX9303582A (en) A FORM OF PHARMACEUTICAL DOSE UNIT OF THE SOFT GELATIN CAPSULE TYPE CONTAINING LYSINE CLONIXINATE AND A PROCEDURE FOR ITS PREPARATION.
JPS5616408A (en) Composition for drug
EP0073758A1 (en) TREATING VIRUS INFECTIONS LIKE ACNE, DERMATITIS AND ARTHRITIS.
KR970009798A (en) How to Use Iron Chelation Compounds to Reduce Free Radical Damage in Mammals
NL7104752A (en) Anti-alcoholic compsns contng calcium 5-buty